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RUAN, KE-HE
One or more keywords matched the following items that are connected to RUAN, KE-HE
Item TypeName
Academic Article Role of Val509 in time-dependent inhibition of human prostaglandin H synthase-2 cyclooxygenase activity by isoform-selective agents.
Academic Article A profile of the residues in the first intracellular loop critical for Gs-mediated signaling of human prostacyclin receptor characterized by an integrative approach of NMR-experiment and mutagenesis.
Academic Article Characterization of the substrate mimic bound to engineered prostacyclin synthase in solution using high-resolution NMR spectroscopy and mutagenesis: implication of the molecular mechanism in biosynthesis of prostacyclin.
Academic Article A profile of the residues in the second extracellular loop that are critical for ligand recognition of human prostacyclin receptor.
Academic Article Involvement of non-conserved residues important for PGE2 binding to the constrained EP3 eLP2 using NMR and site-directed mutagenesis.
Academic Article Identification of residues important for ligand binding of thromboxane A2 receptor in the second extracellular loop using the NMR experiment-guided mutagenesis approach.
Academic Article Identification of the residues in the helix F/G loop important to catalytic function of membrane-bound prostacyclin synthase.
Concept Mutagenesis, Site-Directed
Concept Mutagenesis
Academic Article Identification of the two-phase mechanism of arachidonic acid regulating inflammatory prostaglandin E2 biosynthesis by targeting COX-2 and mPGES-1.
Academic Article The key residue within the second extracellular loop of human EP3 involved in selectively turning down PGE2- and retaining PGE1-mediated signaling in live cells.
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  • Mutagenesis