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MANCINI, MICHAEL

One or more keywords matched the following properties of MANCINI, MICHAEL

Property	Value
keywords	microscopy, estrogen receptor, androgen receptor, high content analysis, high content screening, monoclonal antibodies, hybridomas, image analysis, drug screening, endocrine disrupting chemicals

One or more keywords matched the following items that are connected to MANCINI, MICHAEL

Item Type	Name
Academic Article	Ligand-mediated assembly and real-time cellular dynamics of estrogen receptor alpha-coactivator complexes in living cells.
Academic Article	Subnuclear trafficking of estrogen receptor-alpha and steroid receptor coactivator-1.
Academic Article	FRAP reveals that mobility of oestrogen receptor-alpha is ligand- and proteasome-dependent.
Academic Article	Coactivators enable glucocorticoid receptor recruitment to fine-tune estrogen receptor transcriptional responses.
Academic Article	Regulation of SRC-3 intercompartmental dynamics by estrogen receptor and phosphorylation.
Academic Article	Estrogen-receptor-alpha exchange and chromatin dynamics are ligand- and domain-dependent.
Academic Article	High-resolution, high-throughput microscopy analyses of nuclear receptor and coregulator function.
Academic Article	Growth factor-induced resistance to tamoxifen is associated with a mutation of estrogen receptor alpha and its phosphorylation at serine 305.
Academic Article	Resistance to antiestrogen arzoxifene is mediated by overexpression of cyclin D1.
Academic Article	Ligand-induced large-scale chromatin dynamics as a biosensor for the detection of estrogen receptor subtype selective ligands.
Academic Article	High content imaging-based assay to classify estrogen receptor-a ligands based on defined mechanistic outcomes.
Academic Article	Peptidylarginine deiminase 2-catalyzed histone H3 arginine 26 citrullination facilitates estrogen receptor a target gene activation.
Academic Article	Activation of estrogen receptor-alpha by E2 or EGF induces temporally distinct patterns of large-scale chromatin modification and mRNA transcription.
Academic Article	The hinge region of the human estrogen receptor determines functional synergy between AF-1 and AF-2 in the quantitative response to estradiol and tamoxifen.
Concept	Estrogens, Non-Steroidal
Concept	Estrogen Receptor Modulators
Concept	Estrogen Antagonists
Concept	Estrogen Receptor beta
Concept	Receptors, Estrogen
Concept	Estrogens
Concept	Estrogen Receptor alpha
Academic Article	Unraveling the regulatory connections between two controllers of breast cancer cell fate.
Academic Article	Defining estrogenic mechanisms of bisphenol A analogs through high throughput microscopy-based contextual assays.
Academic Article	Systems level-based RNAi screening by high content analysis identifies UBR5 as a regulator of estrogen receptor-a protein levels and activity.
Academic Article	Characterizing properties of non-estrogenic substituted bisphenol analogs using high throughput microscopy and image analysis.
Grant	Developmental Reprogramming of Prostate Carcinogenesis by BPA
Grant	Steroid Receptor Function and Nuclear Organization
Grant	High Content Analysis to Identify Biomarkers for Chemopreventive Drug Activity
Academic Article	Estrogen-induced transcription at individual alleles is independent of receptor level and active conformation but can be modulated by coactivators activity.
Academic Article	A Mechanistic High-Content Analysis Assay Using a Chimeric Androgen Receptor That Rapidly Characterizes Androgenic Chemicals.
Academic Article	Classification of estrogenic compounds by coupling high content analysis and machine learning algorithms.
Academic Article	Predicting the Estrogen Receptor Activity of Environmental Chemicals by Single-Cell Image Analysis and Data-driven Modeling.
Academic Article	Endocrine disrupting chemicals differentially alter intranuclear dynamics and transcriptional activation of estrogen receptor-a.
Academic Article	Quality Control for Single Cell Imaging Analytics Using Endocrine Disruptor-Induced Changes in Estrogen Receptor Expression.
Academic Article	Gene transcription regulation by ER at the single cell and allele level.
Academic Article	Characterization of flavonoids with potent and subtype-selective actions on estrogen receptors alpha and beta.

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Estrogens