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DONEHOWER, LAWRENCE

One or more keywords matched the following items that are connected to DONEHOWER, LAWRENCE

Item Type	Name
Academic Article	Does p53 affect organismal aging?
Academic Article	p53: guardian AND suppressor of longevity?
Academic Article	The impact of altered p53 dosage on hematopoietic stem cell dynamics during aging.
Academic Article	Tumor suppressor dosage regulates stem cell dynamics during aging.
Academic Article	Generation and characterization of p53 mutant mice.
Academic Article	Decline and fall of the tumor suppressor.
Academic Article	Altered senescence, apoptosis, and DNA damage response in a mutant p53 model of accelerated aging.
Academic Article	Widespread and tissue specific age-related DNA methylation changes in mice.
Academic Article	Impact papers on aging in 2009.
Academic Article	Insights into aging obtained from p53 mutant mouse models.
Academic Article	Rapamycin as longevity enhancer and cancer preventative agent in the context of p53 deficiency.
Academic Article	Aging hematopoietic stem cells decline in function and exhibit epigenetic dysregulation.
Academic Article	DeltaNp63alpha overexpression induces downregulation of Sirt1 and an accelerated aging phenotype in the mouse.
Academic Article	Altered mammary gland development in the p53+/m mouse, a model of accelerated aging.
Academic Article	Analysis of cellular senescence in culture in vivo: the senescence-associated beta-galactosidase assay.
Academic Article	How does suppression of IGF-1 signaling by DNA damage affect aging and longevity?
Academic Article	Timed somatic deletion of p53 in mice reveals age-associated differences in tumor progression.
Academic Article	Longevity regulation in flies: a role for p53.
Academic Article	Using mice to examine p53 functions in cancer, aging, and longevity.
Academic Article	Mdm2-p53 signaling regulates epidermal stem cell senescence and premature aging phenotypes in mouse skin.
Academic Article	p53 mutant mice that display early ageing-associated phenotypes.
Academic Article	Augmented cancer resistance and DNA damage response phenotypes in PPM1D null mice.
Academic Article	Aging-associated truncated form of p53 interacts with wild-type p53 and alters p53 stability, localization, and activity.
Concept	Cellular Senescence
Concept	Aging, Premature
Concept	Skin Aging
Concept	Aging
Academic Article	REG? deficiency promotes premature aging via the casein kinase 1 pathway.
Academic Article	Enhanced inflammation and attenuated tumor suppressor pathways are associated with oncogene-induced lung tumors in aged mice.
Grant	The effects of Age on Cancer Signaling Pathways in Mice
Grant	Biology of Aging Training Grant
Grant	P53 and Organismal Aging

Search Criteria

Aging