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One or more keywords matched the following properties of FISHER, WILLIAM
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overview Dr. Fisher has focused his entire career on pancreatic cancer and is internationally known for his clinical work as a pancreatic surgeon, basic science research, and clinical research in pancreatic cancer. As Director of the Elkins Pancreas Center at Baylor College of Medicine (BCM) he has developed and coordinates all of the clinical care for a large pancreatic cancer patient population as well as all of the basic science and clinical research related to pancreatic cancer being performed at BCM. Dr. Fisher established a pancreatic cancer tissue resource and an extensive clinical database which serve as a vital resource for research. Dr. Fisher’s lab has studied the influence of gastrointestinal hormones, particularly somatostatin and its receptors, on pancreatic cancer growth, and the relationship between diabetes and pancreatic cancer. Dr. Fisher has also collaborated on projects examining the role PDX-1 as an oncogene, gene therapy, oncolytic virotherapy, vaccination with virus-like particles, and adoptive immunotherapy for pancreatic cancer. He is also actively collaborating with investigators in the Human Genome Sequencing Center at BCM on studies sequencing the genome of pancreatic cancer. Dr. Fisher leads a team of research clinicians dedicated to translating discoveries from the bench to the bedside and has served as principal investigator on more than 15 clinical trials for patients with pancreatic cancer.
One or more keywords matched the following items that are connected to FISHER, WILLIAM
Item TypeName
Academic Article Activation of somatostatin receptor subtype 2 inhibits insulin secretion in the isolated perfused human pancreas.
Academic Article Somatostatin receptor gene transfer inhibits established pancreatic cancer xenografts.
Academic Article Microarray analysis of somatostatin receptor 5-regulated gene expression profiles in murine pancreas.
Academic Article Somatostatin, somatostatin receptors, and pancreatic cancer.
Academic Article Characterization of somatostatin receptor expression in human pancreatic cancer using real-time RT-PCR.
Academic Article Signal transduction in human pancreatic cancer: roles of transforming growth factor beta, somatostatin receptors, and other signal intermediates.
Academic Article PDX-1 expression is associated with islet proliferation in vitro and in vivo.
Academic Article Association between somatostatin receptor 5 gene polymorphisms and pancreatic cancer risk and survival.
Academic Article The hypofunctional effect of P335L single nucleotide polymorphism on SSTR5 function.
Academic Article Transfection of SSTR-1 and SSTR-2 inhibits Panc-1 cell proliferation and renders Panc-1 cells responsive to somatostatin analogue.
Academic Article Somatostatin receptor-1 induces cell cycle arrest and inhibits tumor growth in pancreatic cancer.
Concept Somatostatin
Concept Receptors, Somatostatin
Academic Article Variable effect of streptozotocin-diabetes on the growth of hamster pancreatic cancer (H2T) in the Syrian hamster and nude mouse.
Academic Article Expression of the somatostatin receptor subtype-2 gene predicts response of human pancreatic cancer to octreotide.
Academic Article GI hormonal changes in diabetes influence pancreatic cancer growth.
Academic Article Expression of somatostatin receptor subtype 1-5 genes in human pancreatic cancer.
Grant Role of Somatostatin Receptors in Pancreatic Cancer
Search Criteria
  • Somatostatin