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ROSEN, JEFFREY

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Item Type	Name
Academic Article	Regulatory sequences involved in the hormonal control of casein gene expression.
Academic Article	Detection of casein messenger RNA in hormone-dependent mammary cancer by molecular hybridisation.
Academic Article	Inhibitory effect of cortisol in vitro on 2-deoxyglucose uptake and RNA and protein metabolism in lymphosarcoma P1798.
Academic Article	Inhibition of glucose uptake in lymphosarcoma P1798 by cortisol and its relationship to the biosynthesis of deoxyribonucleic acid.
Academic Article	Effects of cortisol on DNA metabolism in the sensitive and resistant lines of mouse lymphoma P1798.
Academic Article	A comparison of the effect of glucocorticoids on glucose uptake and hexokinase activity in lymphosarcoma P1798.
Academic Article	Quantitation of casein messenger ribonucleic acid sequences using a specific complementary DNA hybridization probe.
Academic Article	Comparative sequence analysis of the mRNAs coding for mouse and rat whey protein.
Academic Article	Localization of the casein gene family to a single mouse chromosome.
Academic Article	Difference between mammary epithelial cells from mature virgin and primiparous mice.
Academic Article	Jak2 is an essential tyrosine kinase involved in pregnancy-mediated development of mammary secretory epithelium.
Academic Article	Inducible dimerization of FGFR1: development of a mouse model to analyze progressive transformation of the mammary gland.
Academic Article	neu/ERBB2 cooperates with p53-172H during mammary tumorigenesis in transgenic mice.
Academic Article	Mechanisms of hormonal prevention of breast cancer.
Academic Article	Signal transducer and activator of transcription (Stat) 5 controls the proliferation and differentiation of mammary alveolar epithelium.
Academic Article	Conditional activation of fibroblast growth factor receptor (FGFR) 1, but not FGFR2, in prostate cancer cells leads to increased osteopontin induction, extracellular signal-regulated kinase activation, and in vivo proliferation.
Academic Article	Prostate-specific expression of p53(R172L) differentially regulates p21, Bax, and mdm2 to inhibit prostate cancer progression and prolong survival.
Academic Article	Distinct roles of fibroblast growth factor receptor 1 and 2 in regulating cell survival and epithelial-mesenchymal transition.
Academic Article	Hormone dependence in premalignant mammary progression.
Academic Article	p190-B RhoGAP regulates mammary ductal morphogenesis.
Academic Article	Identification of tumor-initiating cells in a p53-null mouse model of breast cancer.
Academic Article	Inducible prostate intraepithelial neoplasia with reversible hyperplasia in conditional FGFR1-expressing mice.
Academic Article	Lactogenic hormonal induction of long distance interactions between beta-casein gene regulatory elements.
Academic Article	Haploinsufficiency for p190B RhoGAP inhibits MMTV-Neu tumor progression.
Academic Article	CCAAT/enhancer binding protein beta regulates stem cell activity and specifies luminal cell fate in the mammary gland.
Academic Article	Cell cycle defects contribute to a block in hormone-induced mammary gland proliferation in CCAAT/enhancer-binding protein (C/EBPbeta)-null mice.
Academic Article	The pINDUCER lentiviral toolkit for inducible RNA interference in vitro and in vivo.
Academic Article	Prospective isolation and characterization of committed and multipotent progenitors from immortalized mouse mammary epithelial cells with morphogenic potential.
Academic Article	Progesterone receptor directly inhibits ?-casein gene transcription in mammary epithelial cells through promoting promoter and enhancer repressive chromatin modifications.
Academic Article	Activation of Wnt signaling by chemically induced dimerization of LRP5 disrupts cellular homeostasis.
Academic Article	Progesterone receptor repression of prolactin/signal transducer and activator of transcription 5-mediated transcription of the beta-casein gene in mammary epithelial cells.
Academic Article	On murine mammary epithelial stem cells: discovery, function, and current status.
Academic Article	Pregnancy-induced noncoding RNA (PINC) associates with polycomb repressive complex 2 and regulates mammary epithelial differentiation.
Academic Article	Pleiotropic effects of FGFR1 on cell proliferation, survival, and migration in a 3D mammary epithelial cell model.
Academic Article	WNT/beta-catenin mediates radiation resistance of mouse mammary progenitor cells.
Academic Article	P190-B Rho GTPase-activating protein overexpression disrupts ductal morphogenesis and induces hyperplastic lesions in the developing mammary gland.
Academic Article	FOXC2 expression links epithelial-mesenchymal transition and stem cell properties in breast cancer.
Academic Article	Integration of prolactin and glucocorticoid signaling at the beta-casein promoter and enhancer by ordered recruitment of specific transcription factors and chromatin modifiers.
Academic Article	Mammary tumour virus and casein gene transcription during mouse mammary development.
Academic Article	Crosstalk between the p190-B RhoGAP and IGF signaling pathways is required for embryonic mammary bud development.
Academic Article	Wnt/beta-catenin mediates radiation resistance of Sca1+ progenitors in an immortalized mammary gland cell line.
Academic Article	Fibroblast growth factor receptor 1-transformed mammary epithelial cells are dependent on RSK activity for growth and survival.
Academic Article	The DNA-damage effector checkpoint kinase 1 is essential for chromosome segregation and cytokinesis.
Academic Article	An intraductal human-in-mouse transplantation model mimics the subtypes of ductal carcinoma in situ.
Academic Article	A putative role for microRNA-205 in mammary epithelial cell progenitors.
Academic Article	Chk1 haploinsufficiency results in anemia and defective erythropoiesis.
Academic Article	The ups and downs of miR-205: identifying the roles of miR-205 in mammary gland development and breast cancer.
Academic Article	Fibroblast growth factor receptor signaling dramatically accelerates tumorigenesis and enhances oncoprotein translation in the mouse mammary tumor virus-Wnt-1 mouse model of breast cancer.
Academic Article	Genetic manipulation of individual somatic mammary cells in vivo reveals a master role of STAT5a in inducing alveolar fate commitment and lactogenesis even in the absence of ovarian hormones.
Academic Article	P190B RhoGAP has pro-tumorigenic functions during MMTV-Neu mammary tumorigenesis and metastasis.
Academic Article	Fibroblast growth factor receptor signaling is essential for normal mammary gland development and stem cell function.
Academic Article	P190A RhoGAP is required for mammary gland development.
Academic Article	Targeting CreER(T2) expression to keratin 8-expressing murine simple epithelia using bacterial artificial chromosome transgenesis.
Academic Article	Separation by cell size enriches for mammary stem cell repopulation activity.
Academic Article	Comparative biochemical studies of adriamycin and daunomycin in leukemic cells.
Academic Article	Comparison of the whey acidic protein genes of the rat and mouse.
Academic Article	Isolation and characterization of purified rat casein messenger ribonucleic acids.
Academic Article	A transgenic mouse model for mammary carcinogenesis.
Academic Article	Use of PRKO mice to study the role of progesterone in mammary gland development.
Academic Article	A beta-catenin survival signal is required for normal lobular development in the mammary gland.
Academic Article	Multispecies comparative analysis of a mammalian-specific genomic domain encoding secretory proteins.
Academic Article	Evidence that transgenes encoding components of the Wnt signaling pathway preferentially induce mammary cancers from progenitor cells.
Academic Article	Chk1 is haploinsufficient for multiple functions critical to tumor suppression.
Academic Article	Transcriptional profiling of mammary gland side population cells.
Academic Article	A critical role for the inflammatory response in a mouse model of preneoplastic progression.
Academic Article	Keratin 6 is not essential for mammary gland development.
Academic Article	Defining the ATM-mediated barrier to tumorigenesis in somatic mammary cells following ErbB2 activation.
Academic Article	Selective targeting of radiation-resistant tumor-initiating cells.
Academic Article	Thermal enhancement with optically activated gold nanoshells sensitizes breast cancer stem cells to radiation therapy.
Academic Article	Early-onset aging and defective DNA damage response in Cdc14b-deficient mice.
Academic Article	Altered differentiation and paracrine stimulation of mammary epithelial cell proliferation by conditionally activated Smoothened.
Academic Article	Identification and gene expression profiling of tumor-initiating cells isolated from human osteosarcoma cell lines in an orthotopic mouse model.
Academic Article	Comparative oncogenomics identifies breast tumors enriched in functional tumor-initiating cells.
Academic Article	Stem cell antigen-1 (sca-1) regulates mammary tumor development and cell migration.
Concept	Mammary Tumor Virus, Mouse
Concept	Mice, Knockout
Concept	Mice, Inbred NOD
Concept	Mice, Inbred BALB C
Concept	Mice, Inbred C3H
Concept	Mice, Nude
Concept	Mice, SCID
Concept	Mice, Inbred Strains
Concept	Mice
Concept	Mice, Mutant Strains
Concept	Mice, Inbred C57BL
Concept	Mice, Transgenic
Academic Article	Predicting drug responsiveness in human cancers using genetically engineered mice.
Academic Article	Epigenetic silencing of microRNA-203 is required for EMT and cancer stem cell properties.
Academic Article	Plk2 regulates mitotic spindle orientation and mammary gland development.
Academic Article	Wnt-responsive cancer stem cells are located close to distorted blood vessels and not in hypoxic regions in a p53-null mouse model of human breast cancer.
Academic Article	Paracrine signaling in mammary gland development: what can we learn about intratumoral heterogeneity?
Academic Article	STAT3 signaling is activated preferentially in tumor-initiating cells in claudin-low models of human breast cancer.
Academic Article	Transcriptomic classification of genetically engineered mouse models of breast cancer identifies human subtype counterparts.
Academic Article	The oncogenic STP axis promotes triple-negative breast cancer via degradation of the REST tumor suppressor.
Academic Article	Ror2 regulates branching, differentiation, and actin-cytoskeletal dynamics within the mammary epithelium.
Academic Article	Expression of miR-200c in claudin-low breast cancer alters stem cell functionality, enhances chemosensitivity and reduces metastatic potential.
Academic Article	Intratumoral heterogeneity in a Trp53-null mouse model of human breast cancer.
Academic Article	The increasing complexity of the cancer stem cell paradigm.
Academic Article	Modelling breast cancer: one size does not fit all.
Academic Article	Stop! In the name of transforming growth factor-beta: keeping estrogen receptor-alpha-positive mammary epithelial cells from proliferating.
Academic Article	Stem/progenitor cells in mouse mammary gland development and breast cancer.
Academic Article	Chk1 versus Cdc25: chking one's levels of cellular proliferation.
Academic Article	The role of C/EBPbeta in mammary gland development and breast cancer.
Academic Article	Pregnancy-induced changes in cell-fate in the mammary gland.
Academic Article	The mammary gland as a bioreactor: factors regulating the efficient expression of milk protein-based transgenes.
Academic Article	The regulation of mammary gland development by hormones, growth factors, and oncogenes.
Academic Article	Casein gene expression: from transfection to transgenics.
Academic Article	Long term effects of perinatal injection of estrogen and progesterone on the morphological and biochemical development of the mammary gland.
Academic Article	Engineering transgenes for use in the mammary gland.
Academic Article	Minireview: hormones and mammary cell fate--what will I become when I grow up?
Academic Article	Mammary gland macrophages: pleiotropic functions in mammary development.
Academic Article	Cross-species DNA copy number analyses identifies multiple 1q21-q23 subtype-specific driver genes for breast cancer.
Academic Article	The mammary stem cell hierarchy: a looking glass into heterogeneous breast cancer landscapes.
Academic Article	Mammary Stem Cells and Tumor-Initiating Cells Are More Resistant to Apoptosis and Exhibit Increased DNA Repair Activity in Response to DNA Damage.
Academic Article	PTEN is required to maintain luminal epithelial homeostasis and integrity in the adult mammary gland.
Academic Article	Upregulation of EGFR signaling is correlated with tumor stroma remodeling and tumor recurrence in FGFR1-driven breast cancer.
Academic Article	Oncogenic mTOR signalling recruits myeloid-derived suppressor cells to promote tumour initiation.
Academic Article	A Geometrically-Constrained Mathematical Model of Mammary Gland Ductal Elongation Reveals Novel Cellular Dynamics within the Terminal End Bud.
Academic Article	Genomic profiling of murine mammary tumors identifies potential personalized drug targets for p53-deficient mammary cancers.
Academic Article	TAp63 suppresses mammary tumorigenesis through regulation of the Hippo pathway.
Academic Article	Ror2-mediated alternative Wnt signaling regulates cell fate and adhesion during mammary tumor progression.
Academic Article	WNT-Mediated Regulation of FOXO1 Constitutes a Critical Axis Maintaining Pubertal Mammary Stem Cell Homeostasis.
Academic Article	Pharmacological targeting of MYC-regulated IRE1/XBP1 pathway suppresses MYC-driven breast cancer.
Academic Article	FGFR1-Activated Translation of WNT Pathway Components with Structured 5' UTRs Is Vulnerable to Inhibition of EIF4A-Dependent Translation Initiation.
Academic Article	miR-205 Regulates Basal Cell Identity and Stem Cell Regenerative Potential During Mammary Reconstitution.
Grant	Mouse Models of Metastatic Triple-Negative Breast Cancer for Therapeutic Testing
Grant	Hormonal Regulation of Breast Cancer
Grant	GORDON RESEARCH CONFERENCE ON HORMONE ACTION
Grant	Mouse Models of Human Breast Cancer
Grant	DEVELOPMENT OF A STOCHASTIC MOUSE TO STUDY BREAST CANCER
Academic Article	The MMTV-Wnt1 murine model produces two phenotypically distinct subtypes of mammary tumors with unique therapeutic responses to an EGFR inhibitor.
Academic Article	Immuno-subtyping of breast cancer reveals distinct myeloid cell profiles and immunotherapy resistance mechanisms.
Academic Article	Orthotopic Transplantation of Breast Tumors as Preclinical Models for Breast Cancer.
Academic Article	Protein quality control through endoplasmic reticulum-associated degradation maintains haematopoietic stem cell identity and niche interactions.
Academic Article	TIME Is a Great Healer-Targeting Myeloid Cells in the Tumor Immune Microenvironment to Improve Triple-Negative Breast Cancer Outcomes.
Academic Article	Spliceosome-targeted therapies trigger an antiviral immune response in triple-negative breast cancer.
Academic Article	CD8+ T cells inhibit metastasis and CXCL4 regulates its function.
Academic Article	Morphological screening of mesenchymal mammary tumor organoids to identify drugs that reverse epithelial-mesenchymal transition.
Academic Article	Resistance to natural killer cell immunosurveillance confers a selective advantage to polyclonal metastasis.
Academic Article	Tumor suppressor PLK2 may serve as a biomarker in triple-negative breast cancer for improved response to PLK1 therapeutics.
Academic Article	Chemotherapy Coupled to Macrophage Inhibition Induces T-cell and B-cell Infiltration and Durable Regression in Triple-Negative Breast Cancer.
Academic Article	LEF1 Drives a Central Memory Program and Supports Antitumor Activity of Natural Killer T Cells.
Academic Article	STAT5 confers lactogenic properties in breast tumorigenesis and restricts metastatic potential.
Academic Article	Targeted Inhibition of lncRNA Malat1 Alters the Tumor Immune Microenvironment in Preclinical Syngeneic Mouse Models of Triple-Negative Breast Cancer.
Academic Article	Targeting eIF4A triggers an interferon response to synergize with chemotherapy and suppress triple-negative breast cancer.

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