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FINNELL, RICHARD
One or more keywords matched the following items that are connected to FINNELL, RICHARD
Item TypeName
Academic Article Fuz regulates craniofacial development through tissue specific responses to signaling factors.
Academic Article Cardiovascular abnormalities in Folr1 knockout mice and folate rescue.
Academic Article Fuz controls the morphogenesis and differentiation of hair follicles through the formation of primary cilia.
Academic Article Retinoic acid-dependent signaling pathways and lineage events in the developing mouse spinal cord.
Academic Article Differentially expressed genes in embryonic cardiac tissues of mice lacking Folr1 gene activity.
Academic Article Novel folate binding protein-1 interactions in embryonic orofacial tissue.
Academic Article Defective sumoylation pathway directs congenital heart disease.
Academic Article Cannabinoid receptor 1 signaling in embryo neurodevelopment.
Concept Mice, Knockout
Concept Mice, Inbred C3H
Concept Mice, Inbred Strains
Concept Mice, Quaking
Concept Mice
Concept Mice, Neurologic Mutants
Concept Mice, Inbred DBA
Concept Mice, Mutant Strains
Concept Mice, Inbred C57BL
Concept Mice, Transgenic
Academic Article Transcriptional regulation of the novel Toll-like receptor Tlr13.
Academic Article Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Academic Article Disruption of the ATXN1-CIC complex causes a spectrum of neurobehavioral phenotypes in mice and humans.
Academic Article Teratogenicity of valproate conjugates with anticonvulsant activity in mice.
Academic Article Arsenic-induced gene expression changes in the neural tube of folate transport defective mouse embryos.
Academic Article HuR/methyl-HuR and AUF1 regulate the MAT expressed during liver proliferation, differentiation, and carcinogenesis.
Academic Article Preliminary evidence of phenytoin-induced alterations in embryonic gene expression in a mouse model.
Academic Article Microarray analysis of E9.5 reduced folate carrier (RFC1; Slc19a1) knockout embryos reveals altered expression of genes in the cubilin-megalin multiligand endocytic receptor complex.
Academic Article Biochemical and molecular teratology of fetal hydantoin syndrome.
Academic Article Lack of concordance between heat shock proteins and the development of tolerance to teratogen-induced neural tube defects.
Academic Article Neural and orofacial defects in Folp1 knockout mice [corrected].
Academic Article Fuz mutant mice reveal shared mechanisms between ciliopathies and FGF-related syndromes.
Academic Article Embryonic and maternal heat shock responses to a teratogenic hyperthermic insult.
Academic Article Stereoselective pharmacokinetic analysis of valnoctamide, a CNS-active chiral amide analogue of valproic acid, in dogs, rats, and mice.
Academic Article Enantioselective pharmacodynamic and pharmacokinetic analysis of two chiral CNS-active carbamate derivatives of valproic acid.
Academic Article Valproic acid-induced changes in gene expression during neurulation in a mouse model.
Academic Article Anticonvulsant profile and teratogenicity of 3,3-dimethylbutanoylurea: a potential for a second generation drug to valproic acid.
Academic Article A mouse model of hereditary folate malabsorption: deletion of the PCFT gene leads to systemic folate deficiency.
Academic Article S-Adenosylmethionine increases circulating very-low density lipoprotein clearance in non-alcoholic fatty liver disease.
Academic Article Phenytoin-induced teratogenesis: a molecular basis for the observed developmental delay during neurulation.
Academic Article Mthfr gene ablation enhances susceptibility to arsenic prenatal toxicity.
Academic Article Comparative pharmacodynamic and pharmacokinetic analysis of two anticonvulsant halo derivatives of 2,2,3,3-tetramethylcyclopropanecarboxamide, an amide of a cyclic analog of valproic acid.
Academic Article Mice lacking the folic acid-binding protein Folbp1 are defective in early embryonic development.
Academic Article Genetic basis of susceptibility to environmentally induced neural tube defects.
Academic Article Mouse fetal hydantoin syndrome: effects of maternal seizures.
Academic Article Folic acid protects SWV/Fnn embryo fibroblasts against arsenic toxicity.
Academic Article Autism-Like Behavior and Epigenetic Changes Associated with Autism as Consequences of In Utero Exposure to Environmental Pollutants in a Mouse Model.
Academic Article Identification of two putative novel folate receptor genes in humans and mouse.
Academic Article Developmental expression of morphoregulatory genes in the mouse embryo: an analytical approach using a novel technology.
Academic Article Stereoselective pharmacokinetics and pharmacodynamics of propylisopropyl acetamide, a CNS-active chiral amide analog of valproic acid.
Academic Article Arsenic-induced congenital malformations in genetically susceptible folate binding protein-2 knockout mice.
Academic Article Complementary DNA synthesis in situ: methods and applications.
Academic Article Common hierarchies of susceptibility to the induction of neural tube defects in mouse embryos by valproic acid and its 4-propyl-4-pentenoic acid metabolite.
Academic Article Genetic dissection of hyperthermia-induced neural tube defects in mice.
Academic Article Strain-dependent alterations in the expression of folate pathway genes following teratogenic exposure to valproic acid in a mouse model.
Academic Article Identification and characterization of the human and mouse SLC19A3 gene: a novel member of the reduced folate family of micronutrient transporter genes.
Academic Article C5a receptor signaling prevents folate deficiency-induced neural tube defects in mice.
Academic Article Rare LRP6 variants identified in spina bifida patients.
Academic Article Evaluation of stereoselective anticonvulsant, teratogenic, and pharmacokinetic profile of valnoctylurea (capuride): a chiral stereoisomer of valproic acid urea derivative.
Academic Article The transcobalamin receptor knockout mouse: a model for vitamin B12 deficiency in the central nervous system.
Academic Article Developmental consequences of in utero sodium arsenate exposure in mice with folate transport deficiencies.
Academic Article Mutations in planar cell polarity gene SCRIB are associated with spina bifida.
Academic Article Genetic differences in the duration of the lymphocyte heat shock response in mice.
Academic Article Preliminary evidence for a cocaine-induced embryopathy in mice.
Academic Article Renal tubular reabsorption of folate mediated by folate binding protein 1.
Academic Article Valproic acid-induced skeletal malformations: associated gene expression cascades.
Academic Article Evaluation of the antiallodynic, teratogenic and pharmacokinetic profile of stereoisomers of valnoctamide, an amide derivative of a chiral isomer of valproic acid.
Academic Article Folate transport gene inactivation in mice increases sensitivity to colon carcinogenesis.
Academic Article The heat shock response: potential to screen teratogens.
Academic Article The mammalian gene function resource: the International Knockout Mouse Consortium.
Academic Article Planar cell polarity genes Celsr1 and Vangl2 are necessary for kidney growth, differentiation, and rostrocaudal patterning.
Academic Article Spontaneous neural tube defects in splotch mice supplemented with selected micronutrients.
Academic Article Mapping a chromosomal locus for valproic acid-induced exencephaly in mice.
Academic Article Design and pharmacological activity of glycinamide and N-methoxy amide derivatives of analogs and constitutional isomers of valproic acid.
Academic Article Phenytoin-induced teratogenesis: a mouse model.
Academic Article Folate-regulated changes in gene expression in the anterior neural tube of folate binding protein-1 (Folbp1)-deficient murine embryos.
Academic Article Regulation of folate receptor 1 gene expression in the visceral endoderm.
Academic Article Clinical and experimental studies linking oxidative metabolism to phenytoin-induced teratogenesis.
Academic Article Genes encoding critical transcriptional activators for murine neural tube development and human spina bifida: a case-control study.
Academic Article The application of a chemical determination of N-homocysteinylation levels in developing mouse embryos: implication for folate responsive birth defects.
Academic Article Characterization of carbamazepine metabolism in a mouse model of carbamazepine teratogenicity.
Academic Article Potent anticonvulsant urea derivatives of constitutional isomers of valproic acid.
Academic Article Genetic or nutritional disorders in homocysteine or folate metabolism increase protein N-homocysteinylation in mice.
Academic Article Down regulation of sodium channels in nerve terminals of spontaneously epileptic mice.
Academic Article Effects of folate supplementation on the risk of spontaneous and induced neural tube defects in Splotch mice.
Academic Article Excess S-adenosylmethionine reroutes phosphatidylethanolamine towards phosphatidylcholine and triglyceride synthesis.
Academic Article Mouse Fkbp8 activity is required to inhibit cell death and establish dorso-ventral patterning in the posterior neural tube.
Academic Article Developmental outcome of levetiracetam, its major metabolite in humans, 2-pyrrolidinone N-butyric acid, and its enantiomer (R)-alpha-ethyl-oxo-pyrrolidine acetamide in a mouse model of teratogenicity.
Academic Article The planar cell polarity effector Fuz is essential for targeted membrane trafficking, ciliogenesis and mouse embryonic development.
Academic Article Transcriptional analyses of two mouse models of spina bifida.
Academic Article Untargeted metabolite profiling of murine embryos to reveal metabolic perturbations associated with neural tube closure defects.
Academic Article Protection from phenytoin-induced congenital malformations by coadministration of the antiepileptic drug stiripentol in a mouse model.
Academic Article Valproic acid-induced alterations in growth and neurotrophic factor gene expression in murine embryos [corrected].
Academic Article Preclinical evaluation of 2,2,3,3-tetramethylcyclopropanecarbonyl-urea, a novel, second generation to valproic acid, antiepileptic drug.
Academic Article Effect of treatment with phenobarbital and stiripentol on carbamazepine-induced teratogenicity and reactive metabolite formation.
Academic Article Protein-reactive metabolites of carbamazepine in mouse liver microsomes.
Academic Article Role of Folbp1 in the regional regulation of apoptosis and cell proliferation in the developing neural tube and craniofacies.
Academic Article Syntheses and evaluation of anticonvulsant profile and teratogenicity of novel amide derivatives of branched aliphatic carboxylic acids with 4-aminobenzensulfonamide.
Academic Article Anticonvulsant profile and teratogenicity of N-methyl-tetramethylcyclopropyl carboxamide: a new antiepileptic drug.
Academic Article Folate regulation of axonal regeneration in the rodent central nervous system through DNA methylation.
Academic Article Ribonucleotide reductase subunit R1: a gene conferring sensitivity to valproic acid-induced neural tube defects in mice.
Academic Article The fetal hydantoin syndrome: answers from a mouse model.
Academic Article Arsenic-induced alterations in embryonic transcription factor gene expression: implications for abnormal neural development.
Academic Article Effects of dietary folate intake and folate binding protein-1 (Folbp1) on urinary speciation of sodium arsenate in mice.
Academic Article Importance of folate-homocysteine homeostasis during early embryonic development.
Academic Article Papers from the Eighth International Neural Tube Defects Conference.
Academic Article Identification of vascular disruptor compounds by analysis in zebrafish embryos and mouse embryonic endothelial cells.
Academic Article A new partner for the international knockout mouse consortium.
Academic Article Characterization of the anticonvulsant profile and enantioselective pharmacokinetics of the chiral valproylamide propylisopropyl acetamide in rodents.
Academic Article Identification of novel CELSR1 mutations in spina bifida.
Academic Article Metabolite profiling of whole murine embryos reveals metabolic perturbations associated with maternal valproate-induced neural tube closure defects.
Academic Article Expression patterns of folate binding proteins one and two in the developing mouse embryo.
Academic Article Effects of prenatal cocaine exposure on embryonic expression of sonic hedgehog.
Academic Article Phenytoin-induced alterations in craniofacial gene expression.
Academic Article Developmental consequences of abnormal folate transport during murine heart morphogenesis.
Academic Article Autoantibodies against homocysteinylated protein in a mouse model of folate deficiency-induced neural tube defects.
Academic Article A screen for mutations in human homologues of mice exencephaly genes Tfap2alpha and Msx2 in patients with neural tube defects.
Academic Article Alpha-fluoro-2,2,3,3-tetramethylcyclopropanecarboxamide, a novel potent anticonvulsant derivative of a cyclic analogue of valproic acid.
Academic Article Rfx2 is required for spermatogenesis in the mouse.
Academic Article Molecular basis for skeletal variation: insights from developmental genetic studies in mice.
Academic Article Identification of a growth arrest specific (gas 5) gene by differential display as a candidate gene for determining susceptibility to hyperthermia-induced exencephaly in mice.
Academic Article Initial characterization of mice null for Lphn3, a gene implicated in ADHD and addiction.
Academic Article Folate modulates Hox gene-controlled skeletal phenotypes.
Academic Article Genetic and nutritional deficiencies in folate metabolism influence tumorigenicity in Apcmin/+ mice.
Academic Article State of the art in developmental toxicity screening methods and a way forward: a meeting report addressing embryonic stem cells, whole embryo culture, and zebrafish.
Academic Article Altered gene expression in murine branchial arches following in utero exposure to retinoic acid.
Academic Article Arsenic urinary speciation in Mthfr deficient mice injected with sodium arsenate.
Academic Article Strain differences in phenobarbital-induced teratogenesis in mice.
Academic Article Reproductive consequences of oral arsenate exposure during pregnancy in a mouse model.
Academic Article Strain differences in expression of the murine heat shock response: implications for abnormal neural development.
Academic Article Embryonic development of folate binding protein-1 (Folbp1) knockout mice: Effects of the chemical form, dose, and timing of maternal folate supplementation.
Academic Article Anticonvulsant activity, neural tube defect induction, mutagenicity and pharmacokinetics of a new potent antiepileptic drug, N-methoxy-2,2,3,3-tetramethylcyclopropane carboxamide.
Academic Article Comparative teratogenicity analysis of valnoctamide, risperidone, and olanzapine in mice.
Academic Article Gas chromatographic determination of novel valproyl taurinamide derivatives in mouse and dog plasma.
Academic Article Differences in the patterns of phenytoin-induced malformations following stiripentol coadministration in three inbred mouse strains.
Academic Article Strain differences in heat-induced neural tube defects in mice.
Academic Article Effect of stiripentol dose on phenytoin-induced teratogenesis in a mouse model.
Academic Article Congenital defects among the offspring of epileptic fathers: role of the genotype and phenytoin therapy in a mouse model.
Academic Article Neural tube and craniofacial defects with special emphasis on folate pathway genes.
Academic Article Variable patterns of malformation in the mouse fetal hydantoin syndrome.
Academic Article Functional regulation of P-glycoprotein at the blood-brain barrier in proton-coupled folate transporter (PCFT) mutant mice.
Academic Article 3-Methylcholanthrene and other aryl hydrocarbon receptor agonists directly activate estrogen receptor alpha.
Academic Article Analysis of select folate pathway genes, PAX3, and human T in a Midwestern neural tube defect population.
Academic Article Neurulation abnormalities secondary to altered gene expression in neural tube defect susceptible Splotch embryos.
Academic Article In vitro analysis of the murine heat shock response: implications for reproductive toxicology.
Academic Article Myo-inositol enhances teratogenicity of valproic acid in the mouse.
Academic Article Valproate-induced neural tube defects in folate-binding protein-2 (Folbp2) knockout mice.
Academic Article Arsenic-induced neural tube defects in mice: alterations in cell cycle gene expression.
Academic Article Arsenate-induced maternal glucose intolerance and neural tube defects in a mouse model.
Academic Article Pharmacodynamic and pharmacokinetic analysis of CNS-active constitutional isomers of valnoctamide and sec-butylpropylacetamide--Amide derivatives of valproic acid.
Academic Article Teratogenicity of carbamazepine-10, 11-epoxide and oxcarbazepine in the SWV mouse.
Academic Article Use of a novel genetic mouse model to investigate the role of folate in colitis-associated colon cancer.
Academic Article Seizure control following administration of anticonvulsant drugs in the quaking mouse.
Academic Article A critical role of noggin in developing folate-nonresponsive NTD in Fkbp8 -/- embryos.
Academic Article Folic acid in early pregnancy: a public health success story.
Academic Article Decreased muscarinic acetylcholine receptor number in the central nervous system of the tottering (tg/tg) mouse.
Academic Article Pathobiology and genetics of neural tube defects.
Academic Article Failure of epoxide formation to influence carbamazepine-induced teratogenesis in a mouse model.
Academic Article Investigation of the teratogenic effects of exercise on pregnancy outcome in mice.
Academic Article Cocaine selectively alters neurotransmitter receptor mRNAs in mouse embryos.
Academic Article DNA methylation in Folbp1 knockout mice supplemented with folic acid during gestation.
Academic Article Design and Comparative Evaluation of the Anticonvulsant Profile, Carbonic-Anhydrate Inhibition and Teratogenicity of Novel Carbamate Derivatives of Branched Aliphatic Carboxylic Acids with 4-Aminobenzensulfonamide.
Academic Article Variable patterns in anticonvulsant drug-induced malformations in mice: comparisons of phenytoin and phenobarbital.
Academic Article Anticonvulsant activity, teratogenicity and pharmacokinetics of novel valproyltaurinamide derivatives in mice.
Academic Article Stereoselective anticonvulsant and pharmacokinetic analysis of valnoctamide, a CNS-active derivative of valproic acid with low teratogenic potential.
Academic Article Effects of dietary folate intake and folate binding protein-2 (Folbp2) on urinary speciation of sodium arsenate in mice.
Academic Article Embryonic development in the reduced folate carrier knockout mouse is modulated by maternal folate supplementation.
Academic Article Folate-dependent methylation of septins governs ciliogenesis during neural tube closure.
Academic Article Regulation of Reduced Folate Carrier (RFC) by Vitamin D Receptor at the Blood-Brain Barrier.
Academic Article Formate rescues neural tube defects caused by mutations in Slc25a32.
Academic Article Dominant negative GPR161 rare variants are risk factors of human spina bifida.
Academic Article Teratogenicity of valproic acid and its constitutional isomer, amide derivative valnoctamide in mice.
Academic Article Combining mouse embryonic stem cells and zebrafish embryos to evaluate developmental toxicity of chemical exposure.
Academic Article Tissue biomechanics during cranial neural tube closure measured by Brillouin microscopy and optical coherence tomography.
Academic Article MicroRNA-197 controls ADAM10 expression to mediate MeCP2's role in the differentiation of neuronal progenitors.
Academic Article The TFAP2A-IRF6-GRHL3 genetic pathway is conserved in neurulation.
Grant INTERVENTION STRATEGIES FOR NON-FOLATE RESPONSIVE NEURAL TUBE DEFECTS
Grant THE HEAT SHOCK RESPONSE: POTENTIAL TO SCREEN TERATOGENS
Grant Genetic Regulation of Valproic Acid Teratogenicity
Grant FOLATE RECEPTORS IN CRANIOFACIAL MALFORMATIONS
Grant GENETIC REGULATION OF FOLATE RESPONSIVE BIRTH DEFECTS
Grant Folic Acid, Parental Mutation Rates and the Risk for Neural Tube Defects
Grant FOLATE RECEPTOR KNOCKOUTS, ARSENATE AND BIRTH DEFECTS
Concept Mouse Embryonic Stem Cells
Concept Mice, 129 Strain
Academic Article The interaction of maternal diabetes with mutations that affect folate metabolism and how they affect the development of neural tube defects in mice.
Academic Article Upregulation of reduced folate carrier by vitamin D enhances brain folate uptake in mice lacking folate receptor alpha.
Academic Article New myotonic dystrophy type 1 mouse model.
Academic Article Inhibiting MARSs reduces hyperhomocysteinemia-associated neural tube and congenital heart defects.
Academic Article FKBP8 variants are risk factors for spina bifida.
Academic Article MiR-302 Regulates Glycolysis to Control Cell-Cycle during Neural Tube Closure.
Academic Article Multimodal imaging system combining optical coherence tomography and Brillouin microscopy for neural tube imaging.
Academic Article Embryonic Hypotaurine Levels Contribute to Strain-Dependent Susceptibility in Mouse Models of Valproate-Induced Neural Tube Defects.
Academic Article CIC missense variants contribute to susceptibility for spina bifida.
Academic Article Dual functions of TET1 in germ layer lineage bifurcation distinguished by genomic context and dependence on 5-methylcytosine oxidation.
Academic Article A non-coding insertional mutation of Grhl2 causes gene over-expression and multiple structural anomalies including cleft palate, spina bifida and encephalocele.
Academic Article Dolutegravir-induced neural tube defects in mice are folate responsive.
Academic Article Disruption of Fuz in mouse embryos generates hypoplastic hindbrain development and reduced cranial nerve ganglia.
Academic Article A mutation in TBXT causes congenital vertebral malformations in humans and mice.
Academic Article Pax3 lineage-specific deletion of Gpr161 is associated with spinal neural tube and craniofacial malformations during embryonic development.
Academic Article Selective reprogramming of regulatory T cells in solid tumors can strongly enhance or inhibit tumor growth.
Academic Article Folate regulation of planar cell polarity pathway and F-actin through folate receptor alpha.
Academic Article The novel linkage between Fuz and Gpr161 genes regulates sonic hedgehog signaling during mouse embryonic development.
Academic Article Disruption of Fuz in mouse embryos generates hypoplastic hindbrain development and reduced cranial nerve ganglia.
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