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MILLS, GORDON B

One or more keywords matched the following items that are connected to MILLS, GORDON B

Item Type	Name
Academic Article	BSTA promotes mTORC2-mediated phosphorylation of Akt1 to suppress expression of FoxC2 and stimulate adipocyte differentiation.
Academic Article	Telomere 3' overhang-specific DNA oligonucleotides induce autophagy in malignant glioma cells.
Academic Article	A plant triterpenoid, avicin D, induces autophagy by activation of AMP-activated protein kinase.
Academic Article	Autophagy-inducing agents augment the antitumor effect of telerase-selve oncolytic adenovirus OBP-405 on glioblastoma cells.
Academic Article	Dual targeting of AKT and mammalian target of rapamycin: a potential therapeutic approach for malignant peripheral nerve sheath tumor.
Concept	Sirolimus
Academic Article	LMW-E/CDK2 deregulates acinar morphogenesis, induces tumorigenesis, and associates with the activated b-Raf-ERK1/2-mTOR pathway in breast cancer patients.
Academic Article	Overcoming endocrine resistance due to reduced PTEN levels in estrogen receptor-positive breast cancer by co-targeting mammalian target of rapamycin, protein kinase B, or mitogen-activated protein kinase kinase.
Academic Article	Linking molecular therapeutics to molecular diagnostics: inhibition of the FRAP/RAFT/TOR component of the PI3K pathway preferentially blocks PTEN mutant cells in vitro and in vivo.
Academic Article	Insulin-like growth factor-I inhibits progesterone receptor expression in breast cancer cells via the phosphatidylinositol 3-kinase/Akt/mammalian target of rapamycin pathway: progesterone receptor as a potential indicator of growth factor activity in breast cancer.
Academic Article	Determinants of rapamycin sensitivity in breast cancer cells.
Academic Article	Targeting mammalian target of rapamycin synergistically enhances chemotherapy-induced cytotoxicity in breast cancer cells.
Academic Article	Synergistic augmentation of rapamycin-induced autophagy in malignant glioma cells by phosphatidylinositol 3-kinase/protein kinase B inhibitors.
Academic Article	The tumor suppressor gene ARHI regulates autophagy and tumor dormancy in human ovarian cancer cells.
Academic Article	Mammalian target of rapamycin activator RHEB is frequently overexpressed in human carcinomas and is critical and sufficient for skin epithelial carcinogenesis.
Academic Article	Rapamycin enhances apoptosis and increases sensitivity to cisplatin in vitro.
Academic Article	Cell cycle progression out of G1 sensitizes primary-cultured nontransformed T cells to TCR-mediated apoptosis.
Academic Article	Role of glycogen synthase kinase 3beta in rapamycin-mediated cell cycle regulation and chemosensitivity.
Academic Article	mTOR inhibition induces upstream receptor tyrosine kinase signaling and activates Akt.
Academic Article	Silencing mammalian target of rapamycin signaling by small interfering RNA enhances rapamycin-induced autophagy in malignant glioma cells.
Academic Article	Hyperactivation of phosphatidylinositol-3 kinase promotes escape from hormone dependence in estrogen receptor-positive human breast cancer.
Academic Article	PIK3CA/PTEN mutations and Akt activation as markers of sensitivity to allosteric mTOR inhibitors.
Academic Article	Mammalian target of rapamycin.
Academic Article	Preclinical testing of clinically applicable strategies for overcoming trastuzumab resistance caused by PTEN deficiency.
Academic Article	ATM signals to TSC2 in the cytoplasm to regulate mTORC1 in response to ROS.
Academic Article	PIK3CA mutations associated with gene signature of low mTORC1 signaling and better outcomes in estrogen receptor-positive breast cancer.
Academic Article	Rapamycin regulates stearoyl CoA desaturase 1 expression in breast cancer.
Academic Article	PTEN deficiency is fully penetrant for prostate adenocarcinoma in C57BL/6 mice via mTOR-dependent growth.
Academic Article	Open-label randomized clinical trial of standard neoadjuvant chemotherapy with paclitaxel followed by FEC versus the combination of paclitaxel and everolimus followed by FEC in women with triple receptor-negative breast cancer?.
Academic Article	Catalytic mTOR inhibitors can overcome intrinsic and acquired resistance to allosteric mTOR inhibitors.
Academic Article	Loss of progesterone receptor links to high proliferation and increases from primary to metastatic endometrial cancer lesions.
Academic Article	Inhibition of mTORC1/2 overcomes resistance to MAPK pathway inhibitors mediated by PGC1a and oxidative phosphorylation in melanoma.
Academic Article	Yes-associated protein 1 and transcriptional coactivator with PDZ-binding motif activate the mammalian target of rapamycin complex 1 pathway by regulating amino acid transporters in hepatocellular carcinoma.
Academic Article	A putative biomarker signature for clinically effective AKT inhibition: correlation of in vitro, in vivo and clinical data identifies the importance of modulation of the mTORC1 pathway.
Academic Article	Yes-associated protein 1 and transcriptional coactivator with PDZ-binding motif activate the mammalian target of rapamycin complex 1 pathway by regulating amino acid transporters in hepatocellular carcinoma
Academic Article	Mammalian target of rapamycin activator RHEB is frequently overexpressed in human carcinomas and is critical and sufficient for skin epithelial carcinogenesis (Cancer Research (2010) 70, (3287-3298) DOI
Academic Article	A Unified Approach to Targeting the Lysosome's Degradative and Growth Signaling Roles.
Academic Article	Systems biology approach reveals a link between mTORC1 and G2/M DNA damage checkpoint recovery.
Concept	Mechanistic Target of Rapamycin Complex 1
Concept	Mechanistic Target of Rapamycin Complex 2
Academic Article	Suppression of p16 Induces mTORC1-Mediated Nucleotide Metabolic Reprogramming.

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Sirolimus