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Item Type | Name |
Academic Article
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Kit inhibitor APcK110 induces apoptosis and inhibits proliferation of acute myeloid leukemia cells.
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Academic Article
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Kit inhibitor APcK110 extends survival in an AML xenograft mouse model.
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Concept
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Pyridines
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Academic Article
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Phase 1 study of lonafarnib (SCH 66336) and imatinib mesylate in patients with chronic myeloid leukemia who have failed prior single-agent therapy with imatinib.
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Academic Article
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WP1066 disrupts Janus kinase-2 and induces caspase-dependent apoptosis in acute myelogenous leukemia cells.
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Academic Article
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WP1066, a novel JAK2 inhibitor, suppresses proliferation and induces apoptosis in erythroid human cells carrying the JAK2 V617F mutation.
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Academic Article
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Treatment of FLT3-ITD-positive acute myeloid leukemia relapsing after allogeneic stem cell transplantation with sorafenib.
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Academic Article
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Patterns of molecular response to and relapse after combination of sorafenib, idarubicin, and cytarabine in patients with FLT3 mutant acute myeloid leukemia.
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Academic Article
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Phase I and pharmacodynamic study of Triapine, a novel ribonucleotide reductase inhibitor, in patients with advanced leukemia.
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Academic Article
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Clinical activity of farnesyl transferase inhibitors in hematologic malignancies: possible mechanisms of action.
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Academic Article
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Phase I/II study of combination therapy with sorafenib, idarubicin, and cytarabine in younger patients with acute myeloid leukemia.
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Academic Article
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Pilot study of lonafarnib, a farnesyl transferase inhibitor, in patients with chronic myeloid leukemia in the chronic or accelerated phase that is resistant or refractory to imatinib therapy.
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Academic Article
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Potential role of sorafenib in the treatment of acute myeloid leukemia.
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Academic Article
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Phase I study of sorafenib in patients with refractory or relapsed acute leukemias.
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Academic Article
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ATF4 induction through an atypical integrated stress response to ONC201 triggers p53-independent apoptosis in hematological malignancies.
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Academic Article
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Durable Remissions with Ivosidenib in IDH1-Mutated Relapsed or Refractory AML.
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Academic Article
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Mitochondrial ClpP-Mediated Proteolysis Induces Selective Cancer Cell Lethality.
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Academic Article
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Ivosidenib induces deep durable remissions in patients with newly diagnosed IDH1-mutant acute myeloid leukemia.
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Academic Article
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Isavuconazole as Primary Antifungal Prophylaxis in Patients With Acute Myeloid Leukemia or Myelodysplastic Syndrome: An Open-label, Prospective, Phase 2 Study.
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Academic Article
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Molecular mechanisms mediating relapse following ivosidenib monotherapy in IDH1-mutant relapsed or refractory AML.
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Academic Article
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Ivosidenib or enasidenib combined with intensive chemotherapy in patients with newly diagnosed AML: a phase 1 study.
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Academic Article
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Mutant Isocitrate Dehydrogenase 1 Inhibitor Ivosidenib in Combination With Azacitidine for Newly Diagnosed Acute Myeloid Leukemia.
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Academic Article
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Leukemia stemness and co-occurring mutations drive resistance to IDH inhibitors in acute myeloid leukemia.
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