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One or more keywords matched the following items that are connected to ANDREEFF, MICHAEL
Item TypeName
Academic Article 2-Cyano-3,12-dioxooleana-1,9-dien-28-imidazolide (CDDO-Im) directly targets mitochondrial glutathione to induce apoptosis in pancreatic cancer.
Academic Article The synthetic triterpenoid 2-cyano-3,12-dioxooleana-1,9-dien-28-oic acid induces caspase-dependent and -independent apoptosis in acute myelogenous leukemia.
Concept Caspases
Academic Article Apoptosis repressor with caspase recruitment domain is regulated by MAPK/PI3K and confers drug resistance and survival advantage to AML.
Academic Article Caspase 2 and caspase 3 protein levels as predictors of survival in acute myelogenous leukemia.
Academic Article Drug-resistant breast carcinoma (MCF-7) cells are paradoxically sensitive to apoptosis.
Academic Article Small-molecule XIAP inhibitors derepress downstream effector caspases and induce apoptosis of acute myeloid leukemia cells.
Academic Article A novel ring-substituted diindolylmethane,1,1-bis[3'-(5-methoxyindolyl)]-1-(p-t-butylphenyl) methane, inhibits extracellular signal-regulated kinase activation and induces apoptosis in acute myelogenous leukemia.
Academic Article XIAP antisense oligonucleotide (AEG35156) achieves target knockdown and induces apoptosis preferentially in CD34+38- cells in a phase 1/2 study of patients with relapsed/refractory AML.
Academic Article E1A-mediated paclitaxel sensitization in HER-2/neu-overexpressing ovarian cancer SKOV3.ip1 through apoptosis involving the caspase-3 pathway.
Academic Article Functional blocks in caspase activation pathways are common in leukemia and predict patient response to induction chemotherapy.
Academic Article A method for functional evaluation of caspase activation pathways in intact lymphoid cells using electroporation-mediated protein delivery and flow cytometric analysis.
Academic Article MDM2 antagonists induce p53-dependent apoptosis in AML: implications for leukemia therapy.
Academic Article Apoptosis effector mechanisms: a requiem performed in different keys.
Academic Article XIAP downregulation promotes caspase-dependent inhibition of proteasome activity in AML cells.
Academic Article Novel triterpenoid CDDO-Me is a potent inducer of apoptosis and differentiation in acute myelogenous leukemia.
Academic Article Reexpression of the tumor suppressor gene ARHI induces apoptosis in ovarian and breast cancer cells through a caspase-independent calpain-dependent pathway.
Academic Article Apoptosis. Molecules and mechanisms.
Academic Article Effects of the proteasome inhibitor, bortezomib, on apoptosis in isolated lymphocytes obtained from patients with chronic lymphocytic leukemia.
Academic Article Triptolide induces caspase-dependent cell death mediated via the mitochondrial pathway in leukemic cells.
Academic Article Apoptosis in leukemias: regulation and therapeutic targeting.
Academic Article Apoptosis repressor with caspase recruitment domain modulates second mitochondrial-derived activator of caspases mimetic-induced cell death through BIRC2/MAP3K14 signalling in acute myeloid leukaemia.
Academic Article Proliferation and apoptosis in acute and chronic leukemias and myelodysplastic syndrome.
Grant Anti-Leukemic Activity of the Novel Triterpeniod CDDO
Search Criteria
  • Caspases