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ANDREEFF, MICHAEL
One or more keywords matched the following items that are connected to
ANDREEFF, MICHAEL
Item Type
Name
Academic Article
2-Cyano-3,12-dioxooleana-1,9-dien-28-imidazolide (CDDO-Im) directly targets mitochondrial glutathione to induce apoptosis in pancreatic cancer.
Academic Article
The synthetic triterpenoid 2-cyano-3,12-dioxooleana-1,9-dien-28-oic acid induces caspase-dependent and -independent apoptosis in acute myelogenous leukemia.
Concept
Caspases
Academic Article
Apoptosis repressor with caspase recruitment domain is regulated by MAPK/PI3K and confers drug resistance and survival advantage to AML.
Academic Article
Caspase 2 and caspase 3 protein levels as predictors of survival in acute myelogenous leukemia.
Academic Article
Drug-resistant breast carcinoma (MCF-7) cells are paradoxically sensitive to apoptosis.
Academic Article
Small-molecule XIAP inhibitors derepress downstream effector caspases and induce apoptosis of acute myeloid leukemia cells.
Academic Article
A novel ring-substituted diindolylmethane,1,1-bis[3'-(5-methoxyindolyl)]-1-(p-t-butylphenyl) methane, inhibits extracellular signal-regulated kinase activation and induces apoptosis in acute myelogenous leukemia.
Academic Article
XIAP antisense oligonucleotide (AEG35156) achieves target knockdown and induces apoptosis preferentially in CD34+38- cells in a phase 1/2 study of patients with relapsed/refractory AML.
Academic Article
E1A-mediated paclitaxel sensitization in HER-2/neu-overexpressing ovarian cancer SKOV3.ip1 through apoptosis involving the caspase-3 pathway.
Academic Article
Functional blocks in caspase activation pathways are common in leukemia and predict patient response to induction chemotherapy.
Academic Article
A method for functional evaluation of caspase activation pathways in intact lymphoid cells using electroporation-mediated protein delivery and flow cytometric analysis.
Academic Article
MDM2 antagonists induce p53-dependent apoptosis in AML: implications for leukemia therapy.
Academic Article
Apoptosis effector mechanisms: a requiem performed in different keys.
Academic Article
XIAP downregulation promotes caspase-dependent inhibition of proteasome activity in AML cells.
Academic Article
Novel triterpenoid CDDO-Me is a potent inducer of apoptosis and differentiation in acute myelogenous leukemia.
Academic Article
Reexpression of the tumor suppressor gene ARHI induces apoptosis in ovarian and breast cancer cells through a caspase-independent calpain-dependent pathway.
Academic Article
Apoptosis. Molecules and mechanisms.
Academic Article
Effects of the proteasome inhibitor, bortezomib, on apoptosis in isolated lymphocytes obtained from patients with chronic lymphocytic leukemia.
Academic Article
Triptolide induces caspase-dependent cell death mediated via the mitochondrial pathway in leukemic cells.
Academic Article
Apoptosis in leukemias: regulation and therapeutic targeting.
Academic Article
Apoptosis repressor with caspase recruitment domain modulates second mitochondrial-derived activator of caspases mimetic-induced cell death through BIRC2/MAP3K14 signalling in acute myeloid leukaemia.
Academic Article
Proliferation and apoptosis in acute and chronic leukemias and myelodysplastic syndrome.
Grant
Anti-Leukemic Activity of the Novel Triterpeniod CDDO
Search Criteria
Caspases