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WARGO, JENNIFER
One or more keywords matched the following items that are connected to WARGO, JENNIFER
Item TypeName
Concept Melanoma
Concept Melanoma, Experimental
Academic Article Systematic identification of signaling pathways with potential to confer anticancer drug resistance.
Academic Article Role of dendritic cell phenotype, determinant spreading, and negative costimulatory blockade in dendritic cell-based melanoma immunotherapy.
Academic Article Both CD4 and CD8 T cells mediate equally effective in vivo tumor treatment when engineered with a highly avid TCR targeting tyrosinase.
Academic Article A TCR targeting the HLA-A*0201-restricted epitope of MAGE-A3 recognizes multiple epitopes of the MAGE-A antigen superfamily in several types of cancer.
Academic Article RAF inhibitor resistance is mediated by dimerization of aberrantly spliced BRAF(V600E).
Academic Article BRAF inhibition increases tumor infiltration by T cells and enhances the antitumor activity of adoptive immunotherapy in mice.
Academic Article BRAF inhibition is associated with enhanced melanoma antigen expression and a more favorable tumor microenvironment in patients with metastatic melanoma.
Academic Article Potential role of 5-aza-2'-deoxycytidine induced MAGE-A4 expression in immunotherapy for anaplastic thyroid cancer.
Academic Article MAP kinase pathway alterations in BRAF-mutant melanoma patients with acquired resistance to combined RAF/MEK inhibition.
Academic Article COT drives resistance to RAF inhibition through MAP kinase pathway reactivation.
Academic Article Metastatic tumors in the pancreas in the modern era.
Academic Article Tumour micro-environment elicits innate resistance to RAF inhibitors through HGF secretion.
Academic Article Case records of the Massachusetts General Hospital. Case 21-2013. A 68-year-old man with metastatic melanoma.
Academic Article Hypoxia induces phenotypic plasticity and therapy resistance in melanoma via the tyrosine kinase receptors ROR1 and ROR2.
Academic Article A melanocyte lineage program confers resistance to MAP kinase pathway inhibition.
Academic Article Enhanced tumor responses to dendritic cells in the absence of CD8-positive cells.
Academic Article Surgical management of melanoma.
Academic Article Selective BRAFV600E inhibition enhances T-cell recognition of melanoma without affecting lymphocyte function.
Academic Article A landscape of driver mutations in melanoma.
Academic Article Oncogenic BRAF(V600E) promotes stromal cell-mediated immunosuppression via induction of interleukin-1 in melanoma.
Academic Article The activation of MAPK in melanoma cells resistant to BRAF inhibition promotes PD-L1 expression that is reversible by MEK and PI3K inhibition.
Academic Article An ultraviolet-radiation-independent pathway to melanoma carcinogenesis in the red hair/fair skin background.
Academic Article Elucidating distinct roles for NF1 in melanomagenesis.
Academic Article BCL2A1 is a lineage-specific antiapoptotic melanoma oncogene that confers resistance to BRAF inhibition.
Academic Article Oncogenic BRAF regulates oxidative metabolism via PGC1a and MITF.
Academic Article Natural killer cells play a critical role in the immune response following immunization with melanoma-antigen-engineered dendritic cells.
Academic Article Melanoma genome sequencing reveals frequent PREX2 mutations.
Academic Article Oncogenic NRAS signaling differentially regulates survival and proliferation in melanoma.
Academic Article TORC1 suppression predicts responsiveness to RAF and MEK inhibition in BRAF-mutant melanoma.
Academic Article PDGFRa up-regulation mediated by sonic hedgehog pathway activation leads to BRAF inhibitor resistance in melanoma cells with BRAF mutation.
Academic Article A melanoma cell state distinction influences sensitivity to MAPK pathway inhibitors.
Academic Article Response to BRAF inhibition in melanoma is enhanced when combined with immune checkpoint blockade.
Academic Article Clinical profiling of BCL-2 family members in the setting of BRAF inhibition offers a rationale for targeting de novo resistance using BH3 mimetics.
Academic Article Effective innate and adaptive antimelanoma immunity through localized TLR7/8 activation.
Academic Article The immune microenvironment confers resistance to MAPK pathway inhibitors through macrophage-derived TNFa.
Academic Article Inhibition of mTORC1/2 overcomes resistance to MAPK pathway inhibitors mediated by PGC1a and oxidative phosphorylation in melanoma.
Academic Article Clinical utility of a blood-based BRAF(V600E) mutation assay in melanoma.
Academic Article EPHA2 is a mediator of vemurafenib resistance and a novel therapeutic target in melanoma.
Academic Article Combining targeted therapy and immune checkpoint inhibitors in the treatment of metastatic melanoma.
Academic Article Co-clinical assessment identifies patterns of BRAF inhibitor resistance in melanoma.
Academic Article Use of clinical next-generation sequencing to identify melanomas harboring SMARCB1 mutations.
Academic Article MITF Modulates Therapeutic Resistance through EGFR Signaling.
Academic Article Does It MEK a Difference? Understanding Immune Effects of Targeted Therapy.
Academic Article Downregulation of the Ubiquitin Ligase RNF125 Underlies Resistance of Melanoma Cells to BRAF Inhibitors via JAK1 Deregulation.
Academic Article Utility of BRAF V600E Immunohistochemistry Expression Pattern as a Surrogate of BRAF Mutation Status in 154 Patients with Advanced Melanoma.
Academic Article BRAF Inhibition Generates a Host-Tumor Niche that Mediates Therapeutic Escape.
Academic Article Landscape of Targeted Anti-Cancer Drug Synergies in Melanoma Identifies a Novel BRAF-VEGFR/PDGFR Combination Treatment.
Academic Article Novel Treatments in Development for Melanoma.
Academic Article Loss of PTEN Promotes Resistance to T Cell-Mediated Immunotherapy.
Academic Article Inhibiting Drivers of Non-mutational Drug Tolerance Is a Salvage Strategy for Targeted Melanoma Therapy.
Academic Article sFRP2 in the aged microenvironment drives melanoma metastasis and therapy resistance.
Academic Article Clinicopathological features and clinical outcomes associated with TP53 and BRAFNon-V600 mutations in cutaneous melanoma patients.
Academic Article Clinicopathological features and clinical outcomes associated with TP53 and BRAFN on- V 600 mutations in cutaneous melanoma patients
Academic Article SFRP2 in the aged microenvironment drives melanoma metastasis and therapy resistance
Academic Article Fibronectin induction abrogates the BRAF inhibitor response of BRAF V600E/PTEN-null melanoma cells
Academic Article EPHA2 is a mediator of vemurafenib resistance and a novel therapeutic target in melanoma
Academic Article Landscape of targeted anti-cancer drug synergies in melanoma identifies a novel BRAF-VEGFR/PDGFR combination treatment
Academic Article Inhibiting Drivers of Non-mutational Drug Tolerance Is a Salvage Strategy for Targeted Melanoma Therapy
Academic Article Downregulation of the Ubiquitin Ligase RNF125 Underlies Resistance of Melanoma Cells to BRAF Inhibitors via JAK1 Deregulation
Academic Article Combining targeted therapy and immune checkpoint inhibitors in the treatment of metastatic melanoma
Academic Article Distinct clinical patterns and immune infiltrates are observed at time of progression on targeted therapy versus immune checkpoint blockade for melanoma
Academic Article Human melanoma immunotherapy using tumor antigen-specific T cells generated in humanized mice
Academic Article Uveal melanoma
Academic Article Hypoxia-driven mechanism of vemurafenib resistance in melanoma
Academic Article Combining checkpoint inhibitors and BRAF-targeted agents against metastatic melanoma
Academic Article Association of Vitamin D levels with outcome in patients with melanoma after adjustment for C-reactive protein
Academic Article Future perspectives in melanoma research
Academic Article Association of Vitamin D Levels With Outcome in Patients With Melanoma After Adjustment For C-Reactive Protein.
Academic Article Association between Body Mass Index, C-Reactive Protein Levels, and Melanoma Patient Outcomes.
Academic Article The RNA-binding Protein MEX3B Mediates Resistance to Cancer Immunotherapy by Downregulating HLA-A Expression.
Academic Article Association of body-mass index and outcomes in patients with metastatic melanoma treated with targeted therapy, immunotherapy, or chemotherapy: a retrospective, multicohort analysis.
Academic Article Combining checkpoint inhibitors and BRAF-targeted agents against metastatic melanoma.
Academic Article Evidence of synergy with combined BRAF-targeted therapy and immune checkpoint blockade for metastatic melanoma.
Academic Article Human melanoma immunotherapy using tumor antigen-specific T cells generated in humanized mice.
Academic Article The state of melanoma: challenges and opportunities.
Academic Article Analysis of Immune Signatures in Longitudinal Tumor Samples Yields Insight into Biomarkers of Response and Mechanisms of Resistance to Immune Checkpoint Blockade.
Academic Article Corrigendum: sFRP2 in the aged microenvironment drives melanoma metastasis and therapy resistance.
Academic Article Hypoxia-Driven Mechanism of Vemurafenib Resistance in Melanoma.
Academic Article Distinct clinical patterns and immune infiltrates are observed at time of progression on targeted therapy versus immune checkpoint blockade for melanoma.
Academic Article Clinical, Molecular, and Immune Analysis of Dabrafenib-Trametinib Combination Treatment for BRAF Inhibitor-Refractory Metastatic Melanoma: A Phase 2 Clinical Trial.
Academic Article Uveal melanoma: From diagnosis to treatment and the science in between.
Academic Article Targeting mitochondrial biogenesis to overcome drug resistance to MAPK inhibitors.
Academic Article Update on use of aldesleukin for treatment of high-risk metastatic melanoma.
Academic Article Loss of IFN-? Pathway Genes in Tumor Cells as a Mechanism of Resistance to Anti-CTLA-4 Therapy.
Academic Article Point of care assessment of melanoma tumor signaling and metastatic burden from ?NMR analysis of tumor fine needle aspirates and peripheral blood.
Academic Article Novel algorithmic approach predicts tumor mutation load and correlates with immunotherapy clinical outcomes using a defined gene mutation set.
Academic Article Future perspectives in melanoma research : Meeting report from the "Melanoma Bridge". Napoli, December 1st-4th 2015.
Academic Article Interaction of molecular alterations with immune response in melanoma.
Academic Article Targeting endothelin receptor signalling overcomes heterogeneity driven therapy failure.
Academic Article Immunotherapy resistance: the answers lie ahead - not in front - of us.
Academic Article Feasibility of Ultra-High-Throughput Functional Screening of Melanoma Biopsies for Discovery of Novel Cancer Drug Combinations.
Academic Article An adaptive signaling network in melanoma inflammatory niches confers tolerance to MAPK signaling inhibition.
Academic Article Biomarker Accessible and Chemically Addressable Mechanistic Subtypes of BRAF Melanoma.
Academic Article Parallel profiling of immune infiltrate subsets in uveal melanoma versus cutaneous melanoma unveils similarities and differences: A pilot study.
Academic Article Distinct Cellular Mechanisms Underlie Anti-CTLA-4 and Anti-PD-1 Checkpoint Blockade.
Academic Article Tumor-associated B-cells induce tumor heterogeneity and therapy resistance.
Academic Article Genomic and immune heterogeneity are associated with differential responses to therapy in melanoma.
Academic Article RAF Inhibitor Therapy Promotes Melanocytic Antigen Expression and Enhanced Anti-Tumor Immunity in Melanoma.
Academic Article Metastatic melanoma with balloon/histiocytoid cytomorphology after treatment with immunotherapy: A histologic mimic and diagnostic pitfall.
Academic Article Prospective Analysis of Adoptive TIL Therapy in Patients with Metastatic Melanoma: Response, Impact of Anti-CTLA4, and Biomarkers to Predict Clinical Outcome.
Academic Article Neoadjuvant plus adjuvant dabrafenib and trametinib versus standard of care in patients with high-risk, surgically resectable melanoma: a single-centre, open-label, randomised, phase 2 trial.
Academic Article Granulomatous/sarcoid-like lesions associated with checkpoint inhibitors: a marker of therapy response in a subset of melanoma patients.
Academic Article A Preexisting Rare PIK3CAE545K Subpopulation Confers Clinical Resistance to MEK plus CDK4/6 Inhibition in NRAS Melanoma and Is Dependent on S6K1 Signaling.
Academic Article A phase II study of combined therapy with a BRAF inhibitor (vemurafenib) and interleukin-2 (aldesleukin) in patients with metastatic melanoma.
Academic Article Genetic and Genomic Characterization of 462 Melanoma Patient-Derived Xenografts, Tumor Biopsies, and Cell Lines.
Academic Article A Comprehensive Patient-Derived Xenograft Collection Representing the Heterogeneity of Melanoma.
Academic Article Future perspectives in melanoma research "Melanoma Bridge", Napoli, November 30th-3rd December 2016.
Academic Article Immune Checkpoint Blockade across the Cancer Care Continuum.
Academic Article Combined Analysis of Antigen Presentation and T-cell Recognition Reveals Restricted Immune Responses in Melanoma.
Academic Article A PAX3/BRN2 rheostat controls the dynamics of BRAF mediated MITF regulation in MITFhigh /AXLlow melanoma.
Academic Article Remodeling of the Collagen Matrix in Aging Skin Promotes Melanoma Metastasis and Affects Immune Cell Motility.
Academic Article Anti-CTLA-4 Immunotherapy Does Not Deplete FOXP3+ Regulatory T Cells (Tregs) in Human Cancers.
Academic Article Combination Immunotherapy Development in Melanoma.
Academic Article Defining T Cell States Associated with Response to Checkpoint Immunotherapy in Melanoma.
Academic Article Defining T Cell States Associated with Response to Checkpoint Immunotherapy in Melanoma.
Academic Article Neoadjuvant immune checkpoint blockade in high-risk resectable melanoma.
Academic Article Author Correction: Neoadjuvant immune checkpoint blockade in high-risk resectable melanoma.
Academic Article Publisher Correction: Neoadjuvant immune checkpoint blockade in high-risk resectable melanoma.
Academic Article Comparison of immune infiltrates in melanoma and pancreatic cancer highlights VISTA as a potential target in pancreatic cancer.
Academic Article Molecular Profiling Reveals Unique Immune and Metabolic Features of Melanoma Brain Metastases.
Concept Melanoma-Specific Antigens
Concept gp100 Melanoma Antigen
Academic Article Neoadjuvant therapy for melanoma: is it ready for prime time?
Academic Article Role of Immune Response, Inflammation, and Tumor Immune Response-Related Cytokines/Chemokines in Melanoma Progression.
Academic Article Neoadjuvant systemic therapy in melanoma: recommendations of the International Neoadjuvant Melanoma Consortium.
Academic Article Prognostic model for patient survival in primary anorectal mucosal melanoma: stage at presentation determines relevance of histopathologic features.
Academic Article Sustained Type I interferon signaling as a mechanism of resistance to PD-1 blockade.
Academic Article Functional annotation of melanoma risk loci identifies novel susceptibility genes.
Academic Article Tertiary lymphoid structures improve immunotherapy and survival in melanoma.
Academic Article B cells and tertiary lymphoid structures promote immunotherapy response.
Academic Article Toxicity of Immune Checkpoint Inhibitors: Considerations for the Surgeon.
Academic Article Cumulative Incidence and Predictors of CNS Metastasis for Patients With American Joint Committee on Cancer 8th Edition Stage III Melanoma.
Academic Article Circulating Tumor Cells and Early Relapse in Node-positive Melanoma.
Academic Article Stroma remodeling and reduced cell division define durable response to PD-1 blockade in melanoma.
Academic Article Author Correction: Tertiary lymphoid structures improve immunotherapy and survival in melanoma.
Academic Article Spatially resolved analyses link genomic and immune diversity and reveal unfavorable neutrophil activation in melanoma.
Academic Article Gut Microbiome Modulation Via Fecal Microbiota Transplant to Augment Immunotherapy in Patients with Melanoma or Other Cancers.
Academic Article Melanoma Evolves Complete Immunotherapy Resistance through the Acquisition of a Hypermetabolic Phenotype.
Academic Article Neoadjuvant Therapy for Melanoma: A U.S. Food and Drug Administration-Melanoma Research Alliance Public Workshop.
Academic Article Fecal microbiota transplant promotes response in immunotherapy-refractory melanoma patients.
Academic Article Anti-tumour immunity induces aberrant peptide presentation in melanoma.
Academic Article Tumor-infiltrating mast cells are associated with resistance to anti-PD-1 therapy.
Academic Article Pathological response and survival with neoadjuvant therapy in melanoma: a pooled analysis from the International Neoadjuvant Melanoma Consortium (INMC).
Academic Article Identification of bacteria-derived HLA-bound peptides in melanoma.
Academic Article Nodal Recurrence is a Primary Driver of Early Relapse for Patients with Sentinel Lymph Node-Positive Melanoma in the Modern Therapeutic Era.
Academic Article Resolution of tissue signatures of therapy response in patients with recurrent GBM treated with neoadjuvant anti-PD1.
Academic Article Gut microbiota signatures are associated with toxicity to combined CTLA-4 and PD-1 blockade.
Academic Article Microbiota triggers STING-type I IFN-dependent monocyte reprogramming of the tumor microenvironment.
Academic Article Identification of MicroRNA-mRNA Networks in Melanoma and Their Association with PD-1 Checkpoint Blockade Outcomes.
Academic Article Short-term treatment with multi-drug regimens combining BRAF/MEK-targeted therapy and immunotherapy results in durable responses in Braf-mutated melanoma.
Academic Article Utilization and evolving prescribing practice of opioid and non-opioid analgesics in patients undergoing lymphadenectomy for cutaneous malignancy.
Academic Article Evaluation of Plasma IL-6 in Patients with Melanoma as a Prognostic and Checkpoint Immunotherapy Predictive Biomarker.
Academic Article Dietary fiber and probiotics influence the gut microbiome and melanoma immunotherapy response.
Academic Article Tumor MHC Class I Expression Associates with Intralesional IL2 Response in Melanoma.
Academic Article Neoadjuvant Systemic Therapy (NAST) in Patients with Melanoma: Surgical Considerations by the International Neoadjuvant Melanoma Consortium (INMC).
Academic Article Mechanisms of immune activation and regulation: lessons from melanoma.
Academic Article Outcomes After Sphincter-Sparing Local Therapy for Anorectal Melanoma: 1989 to 2020.
Academic Article Combined tumor and immune signals from genomes or transcriptomes predict outcomes of checkpoint inhibition in melanoma.
Academic Article Neoadjuvant therapy for melanoma: rationale for neoadjuvant therapy and pivotal clinical trials.
Academic Article Neoadjuvant therapy for melanoma: new and evolving concepts.
Academic Article Correction to: Neoadjuvant Systemic Therapy (NAST) in Patients with Melanoma: Surgical Considerations by the International Neoadjuvant Melanoma Consortium (INMC).
Academic Article Androgen receptor blockade promotes response to BRAF/MEK-targeted therapy.
Academic Article Multi-modal molecular programs regulate melanoma cell state.
Academic Article Neoadjuvant relatlimab and nivolumab in resectable melanoma.
Academic Article Obesity Is Associated with Altered Tumor Metabolism in Metastatic Melanoma.
Academic Article Diet-driven microbial ecology underpins associations between cancer immunotherapy outcomes and the gut microbiome.
Academic Article Fucosylation of HLA-DRB1 regulates CD4+ T cell-mediated anti-melanoma immunity and enhances immunotherapy efficacy.
Academic Article Microparticle-Delivered Cxcl9 Prolongs Braf Inhibitor Efficacy in Melanoma.
Academic Article Author Correction: Neoadjuvant relatlimab and nivolumab in resectable melanoma.
Academic Article Neoadjuvant chemotherapy plus nivolumab with or without ipilimumab in operable non-small cell lung cancer: the phase 2 platform NEOSTAR trial.
Academic Article Concurrent intrathecal and intravenous nivolumab in leptomeningeal disease: phase 1 trial interim results.
Academic Article Melanoma metastatic to the adrenal gland: An update on the role of adrenalectomy in multidisciplinary management.
Academic Article Targeting PD-L2-RGMb overcomes microbiome-related immunotherapy resistance.
Academic Article Presence of Circulating Tumor Cells Predates Imaging Detection of Relapse in Patients with Stage III Melanoma.
Academic Article Gut Microbiome in Patients With Early-Stage and Late-Stage Melanoma.
Academic Article Timing is Everything: Neoadjuvant Versus Adjuvant Immunotherapy in Patients with Resectable Metastatic Melanoma.
Academic Article Correction: Timing is Everything: Neoadjuvant Versus Adjuvant Immunotherapy in Patients with Resectable Metastatic Melanoma.
Academic Article Androgen drives melanoma invasiveness and metastatic spread by inducing tumorigenic fucosylation.
Academic Article Randomized Placebo-Controlled, Biomarker-Stratified Phase Ib Microbiome Modulation in Melanoma: Impact of Antibiotic Preconditioning on Microbiome and Immunity.
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  • Melanoma