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WARGO, JENNIFER

One or more keywords matched the following items that are connected to WARGO, JENNIFER

Item Type	Name
Concept	Indoles
Academic Article	RAF inhibitor resistance is mediated by dimerization of aberrantly spliced BRAF(V600E).
Academic Article	BRAF inhibition increases tumor infiltration by T cells and enhances the antitumor activity of adoptive immunotherapy in mice.
Academic Article	BRAF inhibition is associated with enhanced melanoma antigen expression and a more favorable tumor microenvironment in patients with metastatic melanoma.
Academic Article	Potential role of 5-aza-2'-deoxycytidine induced MAGE-A4 expression in immunotherapy for anaplastic thyroid cancer.
Academic Article	COT drives resistance to RAF inhibition through MAP kinase pathway reactivation.
Academic Article	Tumour micro-environment elicits innate resistance to RAF inhibitors through HGF secretion.
Academic Article	Hypoxia induces phenotypic plasticity and therapy resistance in melanoma via the tyrosine kinase receptors ROR1 and ROR2.
Academic Article	EGFR-mediated re-activation of MAPK signaling contributes to insensitivity of BRAF mutant colorectal cancers to RAF inhibition with vemurafenib.
Academic Article	Oncogenic BRAF(V600E) promotes stromal cell-mediated immunosuppression via induction of interleukin-1 in melanoma.
Academic Article	An ultraviolet-radiation-independent pathway to melanoma carcinogenesis in the red hair/fair skin background.
Academic Article	Elucidating distinct roles for NF1 in melanomagenesis.
Academic Article	Oncogenic BRAF regulates oxidative metabolism via PGC1a and MITF.
Academic Article	TORC1 suppression predicts responsiveness to RAF and MEK inhibition in BRAF-mutant melanoma.
Academic Article	PDGFRa up-regulation mediated by sonic hedgehog pathway activation leads to BRAF inhibitor resistance in melanoma cells with BRAF mutation.
Academic Article	A melanoma cell state distinction influences sensitivity to MAPK pathway inhibitors.
Academic Article	Response to BRAF inhibition in melanoma is enhanced when combined with immune checkpoint blockade.
Academic Article	Clinical profiling of BCL-2 family members in the setting of BRAF inhibition offers a rationale for targeting de novo resistance using BH3 mimetics.
Academic Article	EPHA2 is a mediator of vemurafenib resistance and a novel therapeutic target in melanoma.
Academic Article	MITF Modulates Therapeutic Resistance through EGFR Signaling.
Academic Article	BRAF Inhibition Generates a Host-Tumor Niche that Mediates Therapeutic Escape.
Academic Article	Landscape of Targeted Anti-Cancer Drug Synergies in Melanoma Identifies a Novel BRAF-VEGFR/PDGFR Combination Treatment.
Academic Article	sFRP2 in the aged microenvironment drives melanoma metastasis and therapy resistance.
Academic Article	Hypoxia-Driven Mechanism of Vemurafenib Resistance in Melanoma.
Academic Article	Interaction of molecular alterations with immune response in melanoma.
Academic Article	Feasibility of Ultra-High-Throughput Functional Screening of Melanoma Biopsies for Discovery of Novel Cancer Drug Combinations.

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