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CARTER, BING Z
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CARTER, BING Z
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Concept
Caspases
Academic Article
Small-molecule XIAP inhibitors derepress downstream effector caspases and induce apoptosis of acute myeloid leukemia cells.
Academic Article
XIAP antisense oligonucleotide (AEG35156) achieves target knockdown and induces apoptosis preferentially in CD34+38- cells in a phase 1/2 study of patients with relapsed/refractory AML.
Academic Article
XIAP downregulation promotes caspase-dependent inhibition of proteasome activity in AML cells.
Academic Article
Triptolide induces caspase-dependent cell death mediated via the mitochondrial pathway in leukemic cells.
Academic Article
Apoptosis in leukemias: regulation and therapeutic targeting.
Academic Article
Apoptosis repressor with caspase recruitment domain modulates second mitochondrial-derived activator of caspases mimetic-induced cell death through BIRC2/MAP3K14 signalling in acute myeloid leukaemia.
Academic Article
Nickel pyrithione induces apoptosis in chronic myeloid leukemia cells resistant to imatinib via both Bcr/Abl-dependent and Bcr/Abl-independent mechanisms.
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Caspases