Item Type | Name |
Academic Article
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Functional proteomics can define prognosis and predict pathologic complete response in patients with breast cancer.
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Concept
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Proteomics
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Academic Article
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Kinome siRNA-phosphoproteomic screen identifies networks regulating AKT signaling.
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Academic Article
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Coordinate phosphorylation of multiple residues on single AKT1 and AKT2 molecules.
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Academic Article
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Ischemia in tumors induces early and sustained phosphorylation changes in stress kinase pathways but does not affect global protein levels.
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Academic Article
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Analysis of molecular aberrations in ovarian cancer allows novel target identification.
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Academic Article
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Validation of reverse phase protein array for practical screening of potential biomarkers in serum and plasma: accurate detection of CA19-9 levels in pancreatic cancer.
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Academic Article
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Integrative analysis of cyclin protein levels identifies cyclin b1 as a classifier and predictor of outcomes in breast cancer.
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Academic Article
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Functional proteomics characterization of residual breast cancer after neoadjuvant systemic chemotherapy.
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Academic Article
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TCPA: a resource for cancer functional proteomics data.
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Academic Article
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Favorable modulation of benign breast tissue and serum risk biomarkers is associated with > 10 % weight loss in postmenopausal women.
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Academic Article
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Modeling precision treatment of breast cancer.
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Academic Article
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Proteomic characterization of breast cancer xenografts identifies early and late bevacizumab-induced responses and predicts effective drug combinations.
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Academic Article
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Promising directions for the diagnosis and management of gynecological cancers.
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Academic Article
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Individualized molecular medicine: linking functional proteomics to select therapeutics targeting the PI3K pathway for specific patients.
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Academic Article
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Functional proteomic profiling of AML predicts response and survival.
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Academic Article
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Integrative analysis of proteomic signatures, mutations, and drug responsiveness in the NCI 60 cancer cell line set.
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Academic Article
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Proteomic profiling identifies pathways dysregulated in non-small cell lung cancer and an inverse association of AMPK and adhesion pathways with recurrence.
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Academic Article
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Quantitative proteomic analysis in breast cancer.
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Academic Article
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Phosphoproteomic mass spectrometry profiling links Src family kinases to escape from HER2 tyrosine kinase inhibition.
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Academic Article
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A Technical Assessment of the Utility of Reverse Phase Protein Arrays for the Study of the Functional Proteome in Non-microdissected Human Breast Cancers.
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Academic Article
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Proteomic profiling identifies dysregulated pathways in small cell lung cancer and novel therapeutic targets including PARP1.
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Academic Article
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Predicting time to ovarian carcinoma recurrence using protein markers.
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Academic Article
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Future for ovarian cancer screening: novel markers from emerging technologies of transcriptional profiling and proteomics.
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Academic Article
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An integrative genomic and proteomic analysis of PIK3CA, PTEN, and AKT mutations in breast cancer.
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Academic Article
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A systems approach to analysis of molecular complexity in breast cancer.
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Academic Article
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Future of personalized medicine in oncology: a systems biology approach.
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Academic Article
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Functional proteomic analysis of advanced serous ovarian cancer using reverse phase protein array: TGF-beta pathway signaling indicates response to primary chemotherapy.
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Academic Article
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Identification of optimal drug combinations targeting cellular networks: integrating phospho-proteomics and computational network analysis.
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Academic Article
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Two phases of mitogenic signaling unveil roles for p53 and EGR1 in elimination of inconsistent growth signals.
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Academic Article
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A time-series DDP for functional proteomics profiles.
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Academic Article
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An epithelial-mesenchymal transition gene signature predicts resistance to EGFR and PI3K inhibitors and identifies Axl as a therapeutic target for overcoming EGFR inhibitor resistance.
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Academic Article
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Systematic analysis of genotype-specific drug responses in cancer.
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Academic Article
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Network inference using steady-state data and Goldbeter-Koshland kinetics. [corrected].
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Academic Article
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Proteomic classification of breast cancer.
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Academic Article
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Use of reverse phase protein microarrays and reference standard development for molecular network analysis of metastatic ovarian carcinoma.
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Academic Article
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Functional proteomics characterization of residual triple-negative breast cancer after standard neoadjuvant chemotherapy.
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Academic Article
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Elafin drives poor outcome in high-grade serous ovarian cancers and basal-like breast tumors.
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Academic Article
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A functional proteogenomic analysis of endometrioid and clear cell carcinomas using reverse phase protein array and mutation analysis: protein expression is histotype-specific and loss of ARID1A/BAF250a is associated with AKT phosphorylation.
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Academic Article
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Realizing the promise of reverse phase protein arrays for clinical, translational, and basic research: a workshop report: the RPPA (Reverse Phase Protein Array) society.
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Academic Article
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A pan-cancer proteomic perspective on The Cancer Genome Atlas.
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Academic Article
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Development of a robust classifier for quality control of reverse-phase protein arrays.
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Academic Article
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Molecular profiling of endometrial carcinoma precursor, primary and metastatic lesions suggests different targets for treatment in obese compared to non-obese patients.
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Academic Article
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An Integrated Molecular Analysis of Lung Adenocarcinomas Identifies Potential Therapeutic Targets among TTF1-Negative Tumors, Including DNA Repair Proteins and Nrf2.
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Academic Article
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A putative biomarker signature for clinically effective AKT inhibition: correlation of in vitro, in vivo and clinical data identifies the importance of modulation of the mTORC1 pathway.
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Academic Article
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Functional proteomics identifies miRNAs to target a p27/Myc/phospho-Rb signature in breast and ovarian cancer
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Academic Article
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Using reverse-phase protein arrays as pharmacodynamic assays for functional proteomics, biomarker discovery, and drug development in cancer
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Academic Article
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Applications of proteomics to clinical questions in breast cancer
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Academic Article
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Systematic Functional Annotation of Somatic Mutations in Cancer.
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Academic Article
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A-to-I RNA Editing Contributes to Proteomic Diversity in Cancer.
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Academic Article
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Clinical and genomic landscape of gastric cancer with a mesenchymal phenotype.
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Academic Article
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Functional proteomics identifies miRNAs to target a p27/Myc/phospho-Rb signature in breast and ovarian cancer.
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Academic Article
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Proteomic Characterization of Head and Neck Cancer Patient-Derived Xenografts.
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Academic Article
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New era of integrated cancer biomarker discovery using reverse-phase protein arrays.
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Academic Article
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Personalized Preclinical Trials in BRAF Inhibitor-Resistant Patient-Derived Xenograft Models Identify Second-Line Combination Therapies.
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Academic Article
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Functional proteomics identifies miRNAs to target a p27/Myc/phospho-Rb signature in breast and ovarian cancer.
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Academic Article
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Comprehensive Characterization of Molecular Differences in Cancer between Male and Female Patients.
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Academic Article
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Using reverse-phase protein arrays as pharmacodynamic assays for functional proteomics, biomarker discovery, and drug development in cancer.
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Academic Article
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Characterization of Human Cancer Cell Lines by Reverse-phase Protein Arrays.
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Academic Article
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Identifying Abundant Immunotherapy and Other Targets in Solid Tumors: Integrating RNA-seq and Mass Spectrometry Proteomics Data Sets.
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Academic Article
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Proteomic Features of Colorectal Cancer Identify Tumor Subtypes Independent of Oncogenic Mutations and Independently Predict Relapse-Free Survival.
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Academic Article
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Explore, Visualize, and Analyze Functional Cancer Proteomic Data Using the Cancer Proteome Atlas.
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Academic Article
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Multi-omics analysis reveals neoantigen-independent immune cell infiltration in copy-number driven cancers.
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Academic Article
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Implementation of a Multiplex and Quantitative Proteomics Platform for Assessing Protein Lysates Using DNA-Barcoded Antibodies.
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Academic Article
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Co-targeting BET and MEK as salvage therapy for MAPK and checkpoint inhibitor-resistant melanoma.
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Academic Article
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Dual Src and MEK Inhibition Decreases Ovarian Cancer Growth and Targets Tumor Initiating Stem-Like Cells.
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Academic Article
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Credentialing Individual Samples for Proteogenomic Analysis.
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Academic Article
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Personalized Integrated Network Modeling of the Cancer Proteome Atlas.
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Academic Article
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Combined MEK and BCL-2/XL Inhibition Is Effective in High-Grade Serous Ovarian Cancer Patient-Derived Xenograft Models and BIM Levels Are Predictive of Responsiveness.
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Academic Article
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TCPA v3.0: An Integrative Platform to Explore the Pan-Cancer Analysis of Functional Proteomic Data.
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Academic Article
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Identification and validation of a prognostic proteomic signature for cervical cancer.
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Academic Article
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Proteomics advances for precision therapy in ovarian cancer.
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Academic Article
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Predicting Cancer Cell Line Dependencies From the Protein Expression Data of Reverse-Phase Protein Arrays.
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Academic Article
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Which path to follow? Utilizing proteomics to improve therapy choices for breast cancer patients.
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Academic Article
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Multiplex digital spatial profiling of proteins and RNA in fixed tissue.
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Academic Article
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Proteomic analysis of circulating extracellular vesicles identifies potential markers of breast cancer progression, recurrence, and response.
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Academic Article
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Analysis of mutational and proteomic heterogeneity of gastric cancer suggests an effective pipeline to monitor post-treatment tumor burden using circulating tumor DNA.
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Academic Article
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Phase 2 study of buparlisib (BKM120), a pan-class I PI3K inhibitor, in patients with metastatic triple-negative breast cancer.
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Academic Article
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Large-Scale Characterization of Drug Responses of Clinically Relevant Proteins in Cancer Cell Lines.
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Academic Article
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Genomic, Transcriptomic, and Proteomic Profiling of Metastatic Breast Cancer.
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Academic Article
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Spatially interacting phosphorylation sites and mutations in cancer.
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Academic Article
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A Modified Nucleoside 6-Thio-2'-Deoxyguanosine Exhibits Antitumor Activity in Gliomas.
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Academic Article
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Mechanical Stress Signaling in Pancreatic Cancer Cells Triggers p38 MAPK- and JNK-Dependent Cytoskeleton Remodeling and Promotes Cell Migration via Rac1/cdc42/Myosin II.
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Academic Article
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Characterization of anticancer drug resistance by reverse-phase protein array: new targets and strategies.
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Academic Article
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Proteo-genomic characterization of virus-associated liver cancers reveals potential subtypes and therapeutic targets.
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Academic Article
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A multi-omic analysis of MCF10A cells provides a resource for integrative assessment of ligand-mediated molecular and phenotypic responses.
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Academic Article
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Stiff matrix induces exosome secretion to promote tumour growth.
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Academic Article
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Multiplatform Analysis of Intratumoral PTEN Heterogeneity in Melanoma.
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Academic Article
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BRD4 inhibition impairs DNA mismatch repair, induces mismatch repair mutation signatures and creates therapeutic vulnerability to immune checkpoint blockade in MMR-proficient tumors.
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