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WIERDA, WILLIAM G

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Item Type	Name
Academic Article	Amphotericin B lipid complex as prophylaxis of invasive fungal infections in patients with acute myelogenous leukemia and myelodysplastic syndrome undergoing induction chemotherapy.
Academic Article	Prediction model for mortality after intracranial hemorrhage in patients with leukemia.
Academic Article	Multiple-dose granulocyte-macrophage-colony-stimulating factor plus 23-valent polysaccharide pneumococcal vaccine in patients with chronic lymphocytic leukemia: a prospective, randomized trial of safety and immunogenicity.
Academic Article	HLA homozygosity and haplotype bias among patients with chronic lymphocytic leukemia: implications for disease control by physiological immune surveillance.
Academic Article	Generation of functional CLL-specific cord blood CTL using CD40-ligated CLL APC.
Academic Article	Increased expression of CD152 (CTLA-4) by normal T lymphocytes in untreated patients with B-cell chronic lymphocytic leukemia.
Academic Article	Phase II study of alemtuzumab in combination with pentostatin in patients with T-cell neoplasms.
Academic Article	The great imitator: systemic nocardiosis mimicking Richter's transformation in relapsed chronic lymphocytic leukemia.
Concept	Leukemia, Hairy Cell
Concept	Precursor Cell Lymphoblastic Leukemia-Lymphoma
Concept	Leukemia, T-Cell
Concept	Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
Concept	Leukemia, Megakaryoblastic, Acute
Concept	Leukemia, Radiation-Induced
Concept	Leukemia, B-Cell
Concept	Leukemia, Myelomonocytic, Chronic
Concept	Leukemia, Myeloid, Accelerated Phase
Concept	Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative
Concept	Myeloid-Lymphoid Leukemia Protein
Concept	Leukemia, Promyelocytic, Acute
Concept	Leukemia, Lymphoid
Concept	Leukemia, Myeloid
Concept	Leukemia
Concept	Leukemia, Myeloid, Acute
Concept	Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Concept	Leukemia, Prolymphocytic, T-Cell
Concept	Precursor B-Cell Lymphoblastic Leukemia-Lymphoma
Concept	Leukemia, Lymphocytic, Chronic, B-Cell
Concept	Leukemia, Prolymphocytic
Concept	Leukemia, Myeloid, Chronic-Phase
Concept	Graft vs Leukemia Effect
Academic Article	Isoform-selective phosphoinositide 3'-kinase inhibitors inhibit CXCR4 signaling and overcome stromal cell-mediated drug resistance in chronic lymphocytic leukemia: a novel therapeutic approach.
Academic Article	B-cell antigen receptor signaling enhances chronic lymphocytic leukemia cell migration and survival: specific targeting with a novel spleen tyrosine kinase inhibitor, R406.
Academic Article	Diverse marrow stromal cells protect CLL cells from spontaneous and drug-induced apoptosis: development of a reliable and reproducible system to assess stromal cell adhesion-mediated drug resistance.
Academic Article	Impaired bactericidal but not fungicidal activity of polymorphonuclear neutrophils in patients with chronic lymphocytic leukemia.
Academic Article	Targeting BTK with ibrutinib in relapsed chronic lymphocytic leukemia.
Academic Article	Phase I-II clinical trial of oxaliplatin, fludarabine, cytarabine, and rituximab therapy in aggressive relapsed/refractory chronic lymphocytic leukemia or Richter syndrome.
Academic Article	Therapy-related myeloid neoplasms following fludarabine, cyclophosphamide, and rituximab (FCR) treatment in patients with chronic lymphocytic leukemia/small lymphocytic lymphoma.
Academic Article	Ibrutinib as initial therapy for elderly patients with chronic lymphocytic leukaemia or small lymphocytic lymphoma: an open-label, multicentre, phase 1b/2 trial.
Academic Article	Three-year follow-up of treatment-na?ve and previously treated patients with CLL and SLL receiving single-agent ibrutinib.
Academic Article	Chronic lymphocytic leukemia.
Academic Article	Gene therapy of hematologic malignancies.
Academic Article	Plasma interleukin 8 level predicts for survival in chronic lymphocytic leukaemia.
Academic Article	Treatment of Philadelphia chromosome-positive chronic myelogenous leukemia with weekly polyethylene glycol formulation of interferon-alpha-2b and low-dose cytosine arabinoside.
Academic Article	Changes associated with the development of resistance to imatinib (STI571) in two leukemia cell lines expressing p210 Bcr/Abl protein.
Academic Article	Increased mitochondrial biogenesis in primary leukemia cells: the role of endogenous nitric oxide and impact on sensitivity to fludarabine.
Academic Article	Adaptive randomized study of idarubicin and cytarabine alone or with interleukin-11 as induction therapy in patients aged 50 or above with acute myeloid leukemia or high-risk myelodysplastic syndromes.
Academic Article	Adult acute megakaryocytic leukemia: an analysis of 37 patients treated at M.D. Anderson Cancer Center.
Academic Article	Eradication of minimal residual disease in hairy cell leukemia.
Academic Article	Chemoimmunotherapy with hyper-CVAD plus rituximab for the treatment of adult Burkitt and Burkitt-type lymphoma or acute lymphoblastic leukemia.
Academic Article	T-cell large granular lymphocytic (T-LGL) leukemia: experience in a single institution over 8 years.
Academic Article	Gene therapy and active immune therapy of hematologic malignancies.
Academic Article	The natural history of fludarabine-refractory chronic lymphocytic leukemia patients who fail alemtuzumab or have bulky lymphadenopathy.
Academic Article	Chronic myeloid leukemia and gastrointestinal stromal tumor: simultaneous presentation.
Academic Article	Customized oligonucleotide array-based comparative genomic hybridization as a clinical assay for genomic profiling of chronic lymphocytic leukemia.
Academic Article	High-level expression of the T-cell chemokines CCL3 and CCL4 by chronic lymphocytic leukemia B cells in nurselike cell cocultures and after BCR stimulation.
Academic Article	Effective treatment of acute promyelocytic leukemia with all-trans-retinoic acid, arsenic trioxide, and gemtuzumab ozogamicin.
Academic Article	Caspase-8 dependent histone acetylation by a novel proteasome inhibitor, NPI-0052: a mechanism for synergy in leukemia cells.
Academic Article	Significance of suboptimal response to imatinib, as defined by the European LeukemiaNet, in the long-term outcome of patients with early chronic myeloid leukemia in chronic phase.
Academic Article	Eltrombopag, a second-generation thrombopoietin receptor agonist, for chronic lymphocytic leukemia-associated ITP.
Academic Article	Phase I and pharmacologic study of SNS-032, a potent and selective Cdk2, 7, and 9 inhibitor, in patients with advanced chronic lymphocytic leukemia and multiple myeloma.
Academic Article	Clinical impact of dose reductions and interruptions of second-generation tyrosine kinase inhibitors in patients with chronic myeloid leukaemia.
Academic Article	Immunohistochemical detection of ZAP70 in chronic lymphocytic leukemia predicts immunoglobulin heavy chain gene mutation status and time to progression.
Academic Article	Chemoimmunotherapy with a modified hyper-CVAD and rituximab regimen improves outcome in de novo Philadelphia chromosome-negative precursor B-lineage acute lymphoblastic leukemia.
Academic Article	Intensive chemotherapy does not benefit most older patients (age 70 years or older) with acute myeloid leukemia.
Academic Article	Chemoimmunotherapy with O-FC in previously untreated patients with chronic lymphocytic leukemia.
Academic Article	Cyclophosphamide, fludarabine, alemtuzumab, and rituximab as salvage therapy for heavily pretreated patients with chronic lymphocytic leukemia.
Academic Article	Ofatumumab is active in patients with fludarabine-refractory CLL irrespective of prior rituximab: results from the phase 2 international study.
Academic Article	Treatment with lenalidomide modulates T-cell immunophenotype and cytokine production in patients with chronic lymphocytic leukemia.
Academic Article	Bax and Bak are required for apogossypolone, a BH3-mimetic, induced apoptosis in chronic lymphocytic leukemia cells.
Academic Article	CARs in chronic lymphocytic leukemia -- ready to drive.
Academic Article	Genomic variation by whole-genome SNP mapping arrays predicts time-to-event outcome in patients with chronic lymphocytic leukemia: a comparison of CLL and HapMap genotypes.
Academic Article	Lenalidomide-induced graft-vs.-Leukemia effect in a patient with chronic lymphocytic leukemia who relapsed after allogeneic stem cell transplant.
Academic Article	Treatment of philadelphia chromosome-positive, accelerated-phase chronic myelogenous leukemia with imatinib mesylate.
Academic Article	Prognostic significance of cytogenetic clonal evolution in patients with chronic myelogenous leukemia on imatinib mesylate therapy.
Academic Article	High expression of activation-induced cytidine deaminase (AID) and splice variants is a distinctive feature of poor-prognosis chronic lymphocytic leukemia.
Academic Article	Prediction of initial cytogenetic response for subsequent major and complete cytogenetic response to imatinib mesylate therapy in patients with Philadelphia chromosome-positive chronic myelogenous leukemia.
Academic Article	Immunologic monitoring in chronic lymphocytic leukemia.
Academic Article	Yttrium-90 ibritumomab tiuxetan radioimmunotherapy in Richter syndrome.
Academic Article	Fludarabine and mitoxantrone for patients with chronic lymphocytic leukemia.
Academic Article	Chronic lymphocytic leukemia B cells of more than 1% of patients express virtually identical immunoglobulins.
Academic Article	Chemoimmunotherapy with fludarabine, cyclophosphamide, and rituximab for relapsed and refractory chronic lymphocytic leukemia.
Academic Article	Early results of a chemoimmunotherapy regimen of fludarabine, cyclophosphamide, and rituximab as initial therapy for chronic lymphocytic leukemia.
Academic Article	Significance of myelofibrosis in early chronic-phase, chronic myelogenous leukemia on imatinib mesylate therapy.
Academic Article	Novel immune-based treatment strategies for chronic lymphocytic leukemia.
Academic Article	Mechanisms of cell death of chronic lymphocytic leukemia lymphocytes by RNA-directed agent, 8-NH2-adenosine.
Academic Article	Clofarabine and cytarabine combination as induction therapy for acute myeloid leukemia (AML) in patients 50 years of age or older.
Academic Article	Results of intensive chemotherapy in 998 patients age 65 years or older with acute myeloid leukemia or high-risk myelodysplastic syndrome: predictive prognostic models for outcome.
Academic Article	Results of a randomized study of 3 schedules of low-dose decitabine in higher-risk myelodysplastic syndrome and chronic myelomonocytic leukemia.
Academic Article	Analysis of human leukaemias and lymphomas using extensive immunophenotypes from an antibody microarray.
Academic Article	Simplified sensitive method for the detection of B-cell clonality in lymphoid malignancies.
Academic Article	Prognostic nomogram and index for overall survival in previously untreated patients with chronic lymphocytic leukemia.
Academic Article	A pilot study of imatinib, low-dose cytarabine and idarubicin for patients with chronic myeloid leukemia in myeloid blast phase.
Academic Article	Overexpression of the CXCR5 chemokine receptor, and its ligand, CXCL13 in B-cell chronic lymphocytic leukemia.
Academic Article	Identification and validation of biomarkers of IgV(H) mutation status in chronic lymphocytic leukemia using microfluidics quantitative real-time polymerase chain reaction technology.
Academic Article	Dynamics of BCR-ABL kinase domain mutations in chronic myeloid leukemia after sequential treatment with multiple tyrosine kinase inhibitors.
Academic Article	Assessment of chronic lymphocytic leukemia and small lymphocytic lymphoma by absolute lymphocyte counts in 2,126 patients: 20 years of experience at the University of Texas M.D. Anderson Cancer Center.
Academic Article	Phase 1 study of the histone deacetylase inhibitor vorinostat (suberoylanilide hydroxamic acid [SAHA]) in patients with advanced leukemias and myelodysplastic syndromes.
Academic Article	A prognostic score for patients with lower risk myelodysplastic syndrome.
Academic Article	Soluble syndecan-1 (sCD138) as a prognostic factor independent of mutation status in patients with chronic lymphocytic leukemia.
Academic Article	The prognostic significance of serum beta2 microglobulin levels in acute myeloid leukemia and prognostic scores predicting survival: analysis of 1,180 patients.
Academic Article	Use of IGHV3-21 in chronic lymphocytic leukemia is associated with high-risk disease and reflects antigen-driven, post-germinal center leukemogenic selection.
Academic Article	AT-101 induces apoptosis in CLL B cells and overcomes stromal cell-mediated Mcl-1 induction and drug resistance.
Academic Article	Relevance of the immunoglobulin VH somatic mutation status in patients with chronic lymphocytic leukemia treated with fludarabine, cyclophosphamide, and rituximab (FCR) or related chemoimmunotherapy regimens.
Academic Article	Chemoimmunotherapy may overcome the adverse prognostic significance of 11q deletion in previously untreated patients with chronic lymphocytic leukemia.
Academic Article	Mechanism of action of SNS-032, a novel cyclin-dependent kinase inhibitor, in chronic lymphocytic leukemia.
Academic Article	A phase 2 study of yttrium-90 ibritumomab tiuxetan (Zevalin) in patients with chronic lymphocytic leukemia.
Academic Article	Influence of bone marrow stromal microenvironment on forodesine-induced responses in CLL primary cells.
Academic Article	Genome-wide DNA methylation profiling of chronic lymphocytic leukemia allows identification of epigenetically repressed molecular pathways with clinical impact.
Academic Article	Predictors and outcome of acute kidney injury in patients with acute myelogenous leukemia or high-risk myelodysplastic syndrome.
Academic Article	Homoharringtonine reduced Mcl-1 expression and induced apoptosis in chronic lymphocytic leukemia.
Academic Article	LDOC1 mRNA is differentially expressed in chronic lymphocytic leukemia and predicts overall survival in untreated patients.
Academic Article	Killing of chronic lymphocytic leukemia by the combination of fludarabine and oxaliplatin is dependent on the activity of XPF endonuclease.
Academic Article	The phosphoinositide 3'-kinase delta inhibitor, CAL-101, inhibits B-cell receptor signaling and chemokine networks in chronic lymphocytic leukemia.
Academic Article	Multivariable model for time to first treatment in patients with chronic lymphocytic leukemia.
Academic Article	Array comparative genomic hybridization analysis identifies recurrent gain of chromosome 2p25.3 involving the ACP1 and MYCN genes in chronic lymphocytic leukemia.
Academic Article	Histone deacetylases mediate the silencing of miR-15a, miR-16, and miR-29b in chronic lymphocytic leukemia.
Academic Article	The prognostic difference of monoallelic versus biallelic deletion of 13q in chronic lymphocytic leukemia.
Academic Article	The Bruton tyrosine kinase inhibitor PCI-32765 thwarts chronic lymphocytic leukemia cell survival and tissue homing in vitro and in vivo.
Academic Article	Making advances in first-line chronic lymphocytic leukemia treatment.
Academic Article	Prognostic factors associated with disease progression and overall survival in patients with myelodysplastic syndromes treated with decitabine.
Academic Article	Phase II study of lenalidomide and rituximab as salvage therapy for patients with relapsed or refractory chronic lymphocytic leukemia.
Academic Article	Acquisition of cytogenetic abnormalities in patients with IPSS defined lower-risk myelodysplastic syndrome is associated with poor prognosis and transformation to acute myelogenous leukemia.
Academic Article	Lenalidomide induces long-lasting responses in elderly patients with chronic lymphocytic leukemia.
Academic Article	Statin and aspirin use is associated with improved outcome of FCR therapy in relapsed/refractory chronic lymphocytic leukemia.
Academic Article	Correlation between FDG/PET, histology, characteristics, and survival in 332 patients with chronic lymphoid leukemia.
Academic Article	Eradication of bone marrow minimal residual disease may prompt early treatment discontinuation in CLL.
Academic Article	Safety and activity of ibrutinib plus rituximab for patients with high-risk chronic lymphocytic leukaemia: a single-arm, phase 2 study.
Academic Article	Immunotherapy of chronic lymphocytic leukemia.
Academic Article	Complete cytogenetic and molecular responses to interferon-alpha-based therapy for chronic myelogenous leukemia are associated with excellent long-term prognosis.
Academic Article	In vivo activation of signal transducer and activator of transcription 1 after CD154 gene therapy for chronic lymphocytic leukemia is associated with clinical and immunologic response.
Academic Article	Effects of age on prognosis with imatinib mesylate therapy for patients with Philadelphia chromosome-positive chronic myelogenous leukemia.
Academic Article	Alemtuzumab as treatment for residual disease after chemotherapy in patients with chronic lymphocytic leukemia.
Academic Article	Survival advantage with imatinib mesylate therapy in chronic-phase chronic myelogenous ;eukemia (CML-CP) after IFN-alpha failure and in late CML-CP, comparison with historical controls.
Academic Article	Phase I and pharmacokinetic study of a low-clearance, unilamellar liposomal formulation of lurtotecan, a topoisomerase 1 inhibitor, in patients with advanced leukemia.
Academic Article	Central nervous system relapse in two patients with chronic myelogenous leukemia in myeloid blastic phase on imatinib mesylate therapy.
Academic Article	Genetics and molecular biology of chronic lymphocytic leukemia.
Academic Article	Phase 1 study of ABT-751, a novel microtubule inhibitor, in patients with refractory hematologic malignancies.
Academic Article	Evolution of treatment strategies in chronic lymphocytic leukemia. Part 2 of a 3-Part series: Advances in the treatment of hematologic malignancies.
Academic Article	T-cell prolymphocytic leukemia: a single-institution experience.
Academic Article	Triapine and cytarabine is an active combination in patients with acute leukemia or myelodysplastic syndrome.
Academic Article	Initial therapy for patients with chronic lymphocytic leukemia.
Academic Article	Activity of alemtuzumab in patients with CD52-positive acute leukemia.
Academic Article	Phase 1/2 study of the combination of 5-aza-2'-deoxycytidine with valproic acid in patients with leukemia.
Academic Article	Immune anaemias in patients with chronic lymphocytic leukaemia treated with fludarabine, cyclophosphamide and rituximab--incidence and predictors.
Academic Article	Safety and clinical activity of the combination of 5-azacytidine, valproic acid, and all-trans retinoic acid in acute myeloid leukemia and myelodysplastic syndrome.
Academic Article	Valganciclovir prevents cytomegalovirus reactivation in patients receiving alemtuzumab-based therapy.
Academic Article	Pilot experience with continuous infusion alemtuzumab in patients with fludarabine-refractory chronic lymphocytic leukemia.
Academic Article	Phase I-II study of oxaliplatin, fludarabine, cytarabine, and rituximab combination therapy in patients with Richter's syndrome or fludarabine-refractory chronic lymphocytic leukemia.
Academic Article	Long-term results of the fludarabine, cyclophosphamide, and rituximab regimen as initial therapy of chronic lymphocytic leukemia.
Academic Article	A phase I and pharmacokinetic study of XK469R (NSC 698215), a quinoxaline phenoxypropionic acid derivative, in patients with refractory acute leukemia.
Academic Article	Effective elimination of fludarabine-resistant CLL cells by PEITC through a redox-mediated mechanism.
Academic Article	Imatinib mesylate dose escalation is associated with durable responses in patients with chronic myeloid leukemia after cytogenetic failure on standard-dose imatinib therapy.
Academic Article	Other malignancies in chronic lymphocytic leukemia/small lymphocytic lymphoma.
Academic Article	Characteristics associated with important clinical end points in patients with chronic lymphocytic leukemia at initial treatment.
Academic Article	New prognostic factors in chronic lymphocytic leukemia.
Academic Article	De novo deletion 17p13.1 chronic lymphocytic leukemia shows significant clinical heterogeneity: the M. D. Anderson and Mayo Clinic experience.
Academic Article	Chronic lymphocytic leukemia: treatment options for patients with refractory disease.
Academic Article	Fludarabine, cyclophosphamide, mitoxantrone plus rituximab (FCM-R) in frontline CLL <70 Years.
Academic Article	Phase 1 multicenter study of vincristine sulfate liposomes injection and dexamethasone in adults with relapsed or refractory acute lymphoblastic leukemia.
Academic Article	Pim kinase inhibitor, SGI-1776, induces apoptosis in chronic lymphocytic leukemia cells.
Academic Article	Phase 1/2 study of lumiliximab combined with fludarabine, cyclophosphamide, and rituximab in patients with relapsed or refractory chronic lymphocytic leukemia.
Academic Article	p53 expression by immunohistochemistry is an important determinant of survival in patients with chronic lymphocytic leukemia receiving frontline chemo-immunotherapy.
Academic Article	Circulating CD52 and CD20 levels at end of treatment predict for progression and survival in patients with chronic lymphocytic leukaemia treated with fludarabine, cyclophosphamide and rituximab (FCR).
Academic Article	Ofatumumab as single-agent CD20 immunotherapy in fludarabine-refractory chronic lymphocytic leukemia.
Academic Article	Alemtuzumab by continuous intravenous infusion followed by subcutaneous injection plus rituximab in the treatment of patients with chronic lymphocytic leukemia recurrence.
Academic Article	microRNA fingerprinting of CLL patients with chromosome 17p deletion identify a miR-21 score that stratifies early survival.
Academic Article	Richter's transformation in chronic lymphocytic leukemia.
Academic Article	First report of phase 2 study of dasatinib with hyper-CVAD for the frontline treatment of patients with Philadelphia chromosome-positive (Ph+) acute lymphoblastic leukemia.
Academic Article	Role of CD20 monoclonal antibodies in previously untreated chronic lymphocytic leukemia.
Academic Article	High serum thymidine kinase 1 level predicts poorer survival in patients with chronic lymphocytic leukemia.
Academic Article	A phase I study of immune gene therapy for patients with CLL using a membrane-stable, humanized CD154.
Academic Article	Chronic lymphocytic leukemia: new concepts for future therapy.
Academic Article	Predictive factors for outcome and response in patients treated with second-generation tyrosine kinase inhibitors for chronic myeloid leukemia in chronic phase after imatinib failure.
Academic Article	What is the best frontline therapy for patients with CLL and 17p deletion?
Academic Article	Substantial susceptibility of chronic lymphocytic leukemia to BCL2 inhibition: results of a phase I study of navitoclax in patients with relapsed or refractory disease.
Academic Article	Predicting survival of patients with hypocellular myelodysplastic syndrome: development of a disease-specific prognostic score system.
Academic Article	Analysis of outcomes in adolescents and young adults with chronic myelogenous leukemia treated with upfront tyrosine kinase inhibitor therapy.
Academic Article	Selective, novel spleen tyrosine kinase (Syk) inhibitors suppress chronic lymphocytic leukemia B-cell activation and migration.
Academic Article	Azacitidine in fludarabine-refractory chronic lymphocytic leukemia: a phase II study.
Academic Article	Prognostic value of miR-155 in individuals with monoclonal B-cell lymphocytosis and patients with B chronic lymphocytic leukemia.
Academic Article	Myelosuppression after frontline fludarabine, cyclophosphamide, and rituximab in patients with chronic lymphocytic leukemia: analysis of persistent and new-onset cytopenia.
Academic Article	Immunotherapy for chronic lymphocytic leukemia in the era of BTK inhibitors.
Academic Article	A phase I and pharmacodynamic study of AT9283, a small-molecule inhibitor of aurora kinases in patients with relapsed/refractory leukemia or myelofibrosis.
Academic Article	Stimulation of the B-cell receptor activates the JAK2/STAT3 signaling pathway in chronic lymphocytic leukemia cells.
Academic Article	Kinetics of CLL cells in tissues and blood during therapy with the BTK inhibitor ibrutinib.
Academic Article	CD40-ligand (CD154) gene therapy for chronic lymphocytic leukemia.
Academic Article	Experience with alemtuzumab plus rituximab in patients with relapsed and refractory lymphoid malignancies.
Academic Article	Fractionated cyclophosphamide, vincristine, liposomal daunorubicin, and dexamethasone plus rituximab and granulocyte-macrophage-colony stimulating factor (GM-CSF) alternating with methotrexate and cytarabine plus rituximab and GM-CSF in patients with Richter syndrome or fludarabine-refractory chronic lymphocytic leukemia.
Academic Article	Bone marrow purging studies in acute myelogenous leukemia using the recombinant anti-CD33 immunotoxin HuM195/rGel.
Academic Article	The significance of myelosuppression during therapy with imatinib mesylate in patients with chronic myelogenous leukemia in chronic phase.
Academic Article	Results of a phase 1-2 study of clofarabine in combination with cytarabine (ara-C) in relapsed and refractory acute leukemias.
Academic Article	Cell death of bioenergetically compromised and transcriptionally challenged CLL lymphocytes by chlorinated ATP.
Academic Article	A proof-of-principle pharmacokinetic, pharmacodynamic, and clinical study with purine nucleoside phosphorylase inhibitor immucillin-H (BCX-1777, forodesine).
Academic Article	CXCR4 is a prognostic marker in acute myelogenous leukemia.
Academic Article	Phase I/II study of the mammalian target of rapamycin inhibitor everolimus (RAD001) in patients with relapsed or refractory hematologic malignancies.
Academic Article	The haematopoietic cell transplantation comorbidity index score is predictive of early death and survival in patients over 60 years of age receiving induction therapy for acute myeloid leukaemia.
Academic Article	Chronic lymphocytic leukaemia CD20 expression is dependent on the genetic subtype: a study of quantitative flow cytometry and fluorescent in-situ hybridization in 510 patients.
Academic Article	Prognostic significance of CD20 expression in adults with de novo precursor B-lineage acute lymphoblastic leukemia.
Academic Article	Clofarabine combinations as acute myeloid leukemia salvage therapy.
Academic Article	Therapeutic advances in leukemia and myelodysplastic syndrome over the past 40 years.
Academic Article	Bleeding diathesis in patients with chronic myelogenous leukemia receiving dasatinib therapy.
Academic Article	Long-term outcome of patients with chronic myeloid leukemia treated with second-generation tyrosine kinase inhibitors after imatinib failure is predicted by the in vitro sensitivity of BCR-ABL kinase domain mutations.
Academic Article	Investigational immunotherapeutics for B-cell malignancies.
Academic Article	Failure is not fatal: long-term remission in refractory acute myeloid leukemia (AML) after graft failure of cord blood stem cells.
Academic Article	Self-administered, subcutaneous alemtuzumab to treat residual disease in patients with chronic lymphocytic leukemia.
Academic Article	CCL3 (MIP-1a) plasma levels and the risk for disease progression in chronic lymphocytic leukemia.
Academic Article	Lenalidomide as initial therapy of elderly patients with chronic lymphocytic leukemia.
Academic Article	Frontline chemoimmunotherapy with fludarabine, cyclophosphamide, alemtuzumab, and rituximab for high-risk chronic lymphocytic leukemia.
Academic Article	A two-gene signature, SKI and SLAMF1, predicts time-to-treatment in previously untreated patients with chronic lymphocytic leukemia.
Academic Article	Pneumonia during remission induction chemotherapy in patients with acute leukemia.
Academic Article	Clinical characteristics, response to therapy, and survival of African American patients diagnosed with chronic lymphocytic leukemia: joint experience of the MD Anderson Cancer Center and Duke University Medical Center.
Academic Article	The Spiegelmer NOX-A12, a novel CXCL12 inhibitor, interferes with chronic lymphocytic leukemia cell motility and causes chemosensitization.
Academic Article	Lenalidomide and rituximab for the initial treatment of patients with chronic lymphocytic leukemia: a multicenter clinical-translational study from the chronic lymphocytic leukemia research consortium.
Academic Article	CD40 activation does not protect chronic lymphocytic leukemia B cells from apoptosis induced by cytotoxic T lymphocytes.
Academic Article	Imatinib mesylate therapy improves survival in patients with newly diagnosed Philadelphia chromosome-positive chronic myelogenous leukemia in the chronic phase: comparison with historic data.
Academic Article	A retrospective comparison of three sequential groups of patients with Recurrent/Refractory chronic lymphocytic leukemia treated with fludarabine-based regimens.
Academic Article	Nonstochastic pairing of immunoglobulin heavy and light chains expressed by chronic lymphocytic leukemia B cells is predicated on the heavy chain CDR3.
Academic Article	Lenalidomide induces complete and partial remissions in patients with relapsed and refractory chronic lymphocytic leukemia.
Academic Article	The antileukemia activity of a human anti-CD40 antagonist antibody, HCD122, on human chronic lymphocytic leukemia cells.
Academic Article	Gossypol, a BH3 mimetic, induces apoptosis in chronic lymphocytic leukemia cells.
Academic Article	Relative value of ZAP-70, CD38, and immunoglobulin mutation status in predicting aggressive disease in chronic lymphocytic leukemia.
Academic Article	New aspects of the treatment of chronic lymphocytic leukemia.
Academic Article	Fludarabine, cyclophosphamide, and rituximab chemoimmunotherapy is highly effective treatment for relapsed patients with CLL.
Academic Article	Stromal cells modulate TCL1 expression, interacting AP-1 components and TCL1-targeting micro-RNAs in chronic lymphocytic leukemia.
Academic Article	Signal transducer and activator of transcription (STAT)-3 regulates microRNA gene expression in chronic lymphocytic leukemia cells.
Academic Article	Evaluation of bendamustine in combination with fludarabine in primary chronic lymphocytic leukemia cells.
Academic Article	Critical appraisal of the role of rituximab in the treatment of patients with previously untreated or treated chronic lymphocytic leukemia (CLL).
Academic Article	Fludarabine, cyclophosphamide and rituximab plus granulocyte macrophage colony-stimulating factor as frontline treatment for patients with chronic lymphocytic leukemia.
Academic Article	Impact of bone marrow stromal cells on Bcl-2 family members in chronic lymphocytic leukemia.
Academic Article	The PI3-kinase delta inhibitor idelalisib (GS-1101) targets integrin-mediated adhesion of chronic lymphocytic leukemia (CLL) cell to endothelial and marrow stromal cells.
Academic Article	Population pharmacokinetics of ofatumumab in patients with chronic lymphocytic leukemia, follicular lymphoma, and rheumatoid arthritis.
Academic Article	STAT3-activated GM-CSFRa translocates to the nucleus and protects CLL cells from apoptosis.
Academic Article	Outcomes of first-line treatment for chronic lymphocytic leukemia with 17p deletion.
Academic Article	Validation of ZAP-70 methylation and its relative significance in predicting outcome in chronic lymphocytic leukemia.
Academic Article	A prognostic model of therapy-related myelodysplastic syndrome for predicting survival and transformation to acute myeloid leukemia.
Academic Article	The use of obinutuzumab in chronic lymphocytic leukemia.
Academic Article	FCR and bevacizumab treatment in patients with relapsed chronic lymphocytic leukemia.
Academic Article	Long-term results of first salvage treatment in CLL patients treated initially with FCR (fludarabine, cyclophosphamide, rituximab).
Academic Article	Second cancers in patients with chronic lymphocytic leukemia who received frontline fludarabine, cyclophosphamide and rituximab therapy: distribution and clinical outcomes.
Academic Article	A phase II study of the combination of rituximab and granulocyte macrophage colony stimulating factor as treatment of patients with chronic lymphocytic leukemia.
Academic Article	Ibrutinib: a paradigm shift in management of CLL.
Academic Article	Progress in novel cellular therapy options for chronic lymphocytic leukemia: the M D Anderson perspective.
Academic Article	Regulation of Mcl-1 expression in context to bone marrow stromal microenvironment in chronic lymphocytic leukemia.
Academic Article	Trisomy 12 is associated with an abbreviated redistribution lymphocytosis during treatment with the BTK inhibitor ibrutinib in patients with chronic lymphocytic leukaemia.
Academic Article	Expression of executioner procaspases and their activation by a procaspase-activating compound in chronic lymphocytic leukemia cells.
Academic Article	Proteasome inhibitor carfilzomib complements ibrutinib's action in chronic lymphocytic leukemia.
Academic Article	Outcomes of patients with chronic lymphocytic leukemia after discontinuing ibrutinib.
Academic Article	High fluorescence in situ hybridization percentage of deletion 11q in patients with chronic lymphocytic leukemia is an independent predictor of adverse outcome.
Academic Article	Aberrant LPL Expression, Driven by STAT3, Mediates Free Fatty Acid Metabolism in CLL Cells.
Academic Article	Chronic lymphocytic leukemia/small lymphocytic lymphoma, version 1.2015.
Academic Article	Ofatumumab monotherapy in fludarabine-refractory chronic lymphocytic leukemia: final results from a pivotal study.
Academic Article	Second cancers and Richter transformation are the leading causes of death in patients with trisomy 12 chronic lymphocytic leukemia.
Academic Article	Three newly approved drugs for chronic lymphocytic leukemia: incorporating ibrutinib, idelalisib, and obinutuzumab into clinical practice.
Academic Article	Ofatumumab retreatment and maintenance in fludarabine-refractory chronic lymphocytic leukaemia patients.
Academic Article	Pharmacological and Protein Profiling Suggests Venetoclax (ABT-199) as Optimal Partner with Ibrutinib in Chronic Lymphocytic Leukemia.
Academic Article	Outcomes of Patients With Chronic Lymphocytic Leukemia and Richter's Transformation After Transplantation Failure.
Academic Article	The phosphoinositide-3-kinase (PI3K)-delta and gamma inhibitor, IPI-145 (Duvelisib), overcomes signals from the PI3K/AKT/S6 pathway and promotes apoptosis in CLL.
Academic Article	Analysis of class I and II histone deacetylase gene expression in human leukemia.
Academic Article	Updates to the management of chronic lymphocytic leukemia.
Academic Article	Sleeping Beauty Transposition of Chimeric Antigen Receptors Targeting Receptor Tyrosine Kinase-Like Orphan Receptor-1 (ROR1) into Diverse Memory T-Cell Populations.
Academic Article	Complex karyotype is a stronger predictor than del(17p) for an inferior outcome in relapsed or refractory chronic lymphocytic leukemia patients treated with ibrutinib-based regimens.
Academic Article	Fludarabine, cyclophosphamide, and multiple-dose rituximab as frontline therapy for chronic lymphocytic leukemia.
Academic Article	Epstein-Barr Virus MicroRNAs are Expressed in Patients with Chronic Lymphocytic Leukemia and Correlate with Overall Survival.
Academic Article	Improvement in clinical outcome of FLT3 ITD mutated acute myeloid leukemia patients over the last one and a half decade.
Academic Article	Long-term follow-up of a phase 2 study of chemotherapy plus dasatinib for the initial treatment of patients with Philadelphia chromosome-positive acute lymphoblastic leukemia.
Academic Article	Combination of hyper-CVAD with ponatinib as first-line therapy for patients with Philadelphia chromosome-positive acute lymphoblastic leukaemia: a single-centre, phase 2 study.
Academic Article	Fludarabine, cyclophosphamide, and rituximab treatment achieves long-term disease-free survival in IGHV-mutated chronic lymphocytic leukemia.
Academic Article	Eliminating minimal residual disease as a therapeutic end point: working toward cure for patients with CLL.
Academic Article	Isolation of a novel chronic lymphocytic leukemic (CLL) cell line and development of an in vivo mouse model of CLL.
Academic Article	Sequential azacitidine and lenalidomide in patients with high-risk myelodysplastic syndromes and acute myeloid leukaemia: a single-arm, phase 1/2 study.
Academic Article	Long-term molecular and cytogenetic response and survival outcomes with imatinib 400 mg, imatinib 800 mg, dasatinib, and nilotinib in patients with chronic-phase chronic myeloid leukaemia: retrospective analysis of patient data from five clinical trials.
Academic Article	Minimal residual disease assessed by multi-parameter flow cytometry is highly prognostic in adult patients with acute lymphoblastic leukaemia.
Academic Article	Acalabrutinib (ACP-196) in Relapsed Chronic Lymphocytic Leukemia.
Academic Article	Ofatumumab and Lenalidomide for Patients with Relapsed or Refractory Chronic Lymphocytic Leukemia: Correlation between Responses and Immune Characteristics.
Academic Article	Incidence and prognostic impact of other cancers in a population of long-term survivors of chronic lymphocytic leukemia.
Academic Article	Clonal evolution in patients with chronic lymphocytic leukaemia developing resistance to BTK inhibition.
Academic Article	High-level ROR1 associates with accelerated disease progression in chronic lymphocytic leukemia.
Academic Article	Frontline therapy with high-dose imatinib versus second generation tyrosine kinase inhibitor in patients with chronic-phase chronic myeloid leukemia-a propensity score analysis
Academic Article	Second cancers and Richter transformation are the leading causes of death in patients with trisomy 12 chronic lymphocytic leukemia
Academic Article	ATM function and its relationship with ATM gene mutations in chronic lymphocytic leukemia with the recurrent deletion (11q22.3-23.2)
Academic Article	Refractory chronic lymphocytic leukemia
Academic Article	Fludarabine, cyclophosphamide, and rituximab treatment achieves long-Term disease-free survival in IGHV-mutated chronic lymphocytic leukemia
Academic Article	Epstein-Barr Virus MicroRNAs are Expressed in Patients with Chronic Lymphocytic Leukemia and Correlate with Overall Survival
Academic Article	Three Newly Approved Drugs for Chronic Lymphocytic Leukemia
Academic Article	Outcomes for patients with chronic lymphocytic leukemia and acute leukemia or myelodysplastic syndrome
Academic Article	A phase II study of the combination of rituximab and granulocyte macrophage colony stimulating factor as treatment of patients with chronic lymphocytic leukemia
Academic Article	Salvage chemoimmunotherapy for patients with relapsed/refractory chronic lymphocytic leukemia
Academic Article	Fludarabine, cyclophosphamide, and multiple-dose rituximab as frontline therapy for chronic lymphocytic leukemia
Academic Article	Acalabrutinib (ACP-196) in relapsed chronic lymphocytic leukemia
Academic Article	Complex karyotype is a stronger predictor than del(17p) for an inferior outcome in relapsed or refractory chronic lymphocytic leukemia patients treated with ibrutinib-based regimens
Academic Article	Preclinical combination of TP-0903, an AXL inhibitor and B-PAC-1, a procaspase-activating compound with ibrutinib in chronic lymphocytic leukemia
Academic Article	Minimal residual disease provides treatment focus for next chronic lymphocytic leukemia advances
Academic Article	Î²₂-microglobulin normalization within 6 months of ibrutinib-based treatment is associated with superior progression-free survival in patients with chronic lymphocytic leukemia
Academic Article	Highlights of the 6th Young Investigators' Meeting on chronic lymphocytic leukemia
Academic Article	Incidence and prognostic impact of other cancers in a population of long-term survivors of chronic lymphocytic leukemia
Academic Article	Long-term follow-up of a phase 2 study of chemotherapy plus dasatinib for the initial treatment of patients with Philadelphia chromosome-positive acute lymphoblastic leukemia
Academic Article	Chronic lymphocytic leukemias
Academic Article	Membranoproliferative glomerulonephritis and acute renal failure in a patient with chronic lymphocytic leukemia
Academic Article	FCR and bevacizumab treatment in patients with relapsed chronic lymphocytic leukemia
Academic Article	Isolation of a novel chronic lymphocytic leukemic (CLL) cell line and development of an in vivo mouse model of CLL
Academic Article	Buparlisib, a PI3K inhibitor, demonstrates acceptable tolerability and preliminary activity in a phase I trial of patients with advanced leukemias
Academic Article	Ofatumumab monotherapy in fludarabine-refractory chronic lymphocytic leukemia
Academic Article	Combination of Pim kinase inhibitors and Bcl-2 antagonists in chronic lymphocytic leukemia cells
Academic Article	Associations of ofatumumab exposure and treatment outcomes in patients with untreated CLL receiving chemoimmunotherapy
Academic Article	Pharmacological and protein profiling suggests venetoclax (ABT-199) as optimal partner with ibrutinib in chronic lymphocytic leukemia
Academic Article	At high levels, constitutively activated STAT3 induces apoptosis of chronic lymphocytic leukemia cells
Academic Article	Reactivation of smac-mediated apoptosis in chronic lymphocytic leukemia cells
Academic Article	Autoimmune cytopenias in patients with chronic lymphocytic leukemia treated with ibrutinib
Academic Article	Ofatumumab and lenalidomide for patients with relapsed or refractory chronic lymphocytic leukemia
Academic Article	A clinical trial for patients with acute myeloid leukemia or myelodysplastic syndromes not eligible for standard clinical trials
Academic Article	Clinical and molecular characteristics of XPO1 mutations in patients with chronic lymphocytic leukemia
Academic Article	A complementary role of multiparameter flow cytometry and high-throughput sequencing for minimal residual disease detection in chronic lymphocytic leukemia
Academic Article	Second cancers in patients with chronic lymphocytic leukemia who received frontline fludarabine, cyclophosphamide and rituximab therapy
Academic Article	Functional differences between IgM and IgD signaling in chronic lymphocytic leukemia
Academic Article	CD154 (CD40-LIGAND) gene therapy for chronic lymphocytic leukemia leads to in vivo activation of the stat1 signaling pathway
Academic Article	Erratum
Academic Article	Analysis of class i and II histone deacetylase gene expression in human leukemia
Academic Article	Carfilzomib triggers cell death in chronic lymphocytic leukemia by inducing proapoptotic and endoplasmic reticulum stress responses
Academic Article	Patient Characteristics and Outcomes in Adolescents and Young Adults (AYA) With Acute Myeloid Leukemia (AML)
Academic Article	Improvement in clinical outcome of FLT3 ITD mutated acute myeloid leukemia patients over the last one and a half decade
Academic Article	A clinical trial for patients with acute myeloid leukemia or myelodysplastic syndromes not eligible for standard clinical trials.
Academic Article	A clinical trial for patients with acute myeloid leukemia or myelodysplastic syndromes not eligible for standard clinical trials.
Academic Article	Cord blood NK cells engineered to express IL-15 and a CD19-targeted CAR show long-term persistence and potent antitumor activity.
Academic Article	B-cell Receptor Signaling Regulates Metabolism in Chronic Lymphocytic Leukemia.
Academic Article	Venetoclax for chronic lymphocytic leukaemia progressing after ibrutinib: an interim analysis of a multicentre, open-label, phase 2 trial.
Academic Article	Venetoclax for patients with chronic lymphocytic leukemia who progressed during or after idelalisib therapy.
Academic Article	Outcomes for patients with chronic lymphocytic leukemia and acute leukemia or myelodysplastic syndrome.
Academic Article	Combination of Pim kinase inhibitors and Bcl-2 antagonists in chronic lymphocytic leukemia cells.
Academic Article	A complementary role of multiparameter flow cytometry and high-throughput sequencing for minimal residual disease detection in chronic lymphocytic leukemia: an European Research Initiative on CLL study.
Academic Article	Targeting BCL2 with Venetoclax in Relapsed Chronic Lymphocytic Leukemia.
Academic Article	Patient Characteristics and Outcomes in Adolescents and Young Adults (AYA) With Acute Myeloid Leukemia (AML).
Academic Article	Analysis of 2013 European LeukaemiaNet (ELN) responses in chronic phase CML across four frontline TKI modalities and impact on clinical outcomes.
Academic Article	Autoimmune cytopenias in patients with chronic lymphocytic leukemia treated with ibrutinib.
Academic Article	Carfilzomib Triggers Cell Death in Chronic Lymphocytic Leukemia by Inducing Proapoptotic and Endoplasmic Reticulum Stress Responses.
Academic Article	At High Levels, Constitutively Activated STAT3 Induces Apoptosis of Chronic Lymphocytic Leukemia Cells.
Academic Article	?2 -microglobulin normalization within 6 months of ibrutinib-based treatment is associated with superior progression-free survival in patients with chronic lymphocytic leukemia.
Academic Article	Preclinical combination of TP-0903, an AXL inhibitor and B-PAC-1, a procaspase-activating compound with ibrutinib in chronic lymphocytic leukemia.
Academic Article	Reactivation of Smac-mediated apoptosis in chronic lymphocytic leukemia cells: mechanistic studies of Smac mimetic.
Academic Article	Associations of ofatumumab exposure and treatment outcomes in patients with untreated CLL receiving chemoimmunotherapy.
Academic Article	Minimal Residual Disease Provides Treatment Focus for Next Chronic Lymphocytic Leukemia Advances.
Academic Article	A phase I-II trial of fludarabine, bendamustine and rituximab (FBR) in previously treated patients with CLL.
Academic Article	Membranoproliferative glomerulonephritis and acute renal failure in a patient with chronic lymphocytic leukemia: Response to obinutuzumab.
Academic Article	Phase I trials using Sleeping Beauty to generate CD19-specific CAR T cells.
Academic Article	Frontline therapy with high-dose imatinib versus second generation tyrosine kinase inhibitor in patients with chronic-phase chronic myeloid leukemia - a propensity score analysis.
Academic Article	Venetoclax in relapsed or refractory chronic lymphocytic leukaemia with 17p deletion: a multicentre, open-label, phase 2 study.
Academic Article	Outcomes of patients with chronic lymphocytic leukemia treated with first-line idelalisib plus rituximab after cessation of treatment for toxicity.
Academic Article	Clinical and molecular characteristics of XPO1 mutations in patients with chronic lymphocytic leukemia.
Academic Article	ATM function and its relationship with ATM gene mutations in chronic lymphocytic leukemia with the recurrent deletion (11q22.3-23.2).
Academic Article	Extended Treatment with Single-Agent Ibrutinib at the 420 mg Dose Leads to Durable Responses in Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma.
Academic Article	Ibrutinib Therapy Increases T Cell Repertoire Diversity in Patients with Chronic Lymphocytic Leukemia.
Academic Article	Leukemia cell proliferation and death in chronic lymphocytic leukemia patients on therapy with the BTK inhibitor ibrutinib.
Academic Article	Long-term Follow-up of Treatment with Ibrutinib and Rituximab in Patients with High-Risk Chronic Lymphocytic Leukemia.
Academic Article	Economic Burden of Chronic Lymphocytic Leukemia in the Era of Oral Targeted Therapies in the United States.
Academic Article	Constitutive Phosphorylation of STAT3 by the CK2-BLNK-CD5 Complex.
Academic Article	Comparison of Acalabrutinib, A Selective Bruton Tyrosine Kinase Inhibitor, with Ibrutinib in Chronic Lymphocytic Leukemia Cells.
Academic Article	Leukemia-cell proliferation and disease progression in patients with early stage chronic lymphocytic leukemia.
Academic Article	Idelalisib and bendamustine combination is synergistic and increases DNA damage response in chronic lymphocytic leukemia cells.
Academic Article	Functional Differences between IgM and IgD Signaling in Chronic Lymphocytic Leukemia.
Academic Article	Buparlisib, a PI3K inhibitor, demonstrates acceptable tolerability and preliminary activity in a phase I trial of patients with advanced leukemias.
Academic Article	PET-positive lymphadenopathy in CLL-Not always Richter transformation.
Academic Article	Chronic myeloid leukemia among patients with a history of prior malignancies: A tale of dual survivorship.
Academic Article	Dynamic changes in CCL3 and CCL4 plasma concentrations in patients with chronic lymphocytic leukaemia managed with observation.
Academic Article	Long-term outcome of acute promyelocytic leukemia treated with all-trans-retinoic acid, arsenic trioxide, and gemtuzumab.
Academic Article	Duvelisib treatment is associated with altered expression of apoptotic regulators that helps in sensitization of chronic lymphocytic leukemia cells to venetoclax (ABT-199).
Academic Article	Ruxolitinib for symptom control in patients with chronic lymphocytic leukaemia: a single-group, phase 2 trial.
Academic Article	NCCN Guidelines Insights: Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma, Version 1.2017.
Academic Article	Long-term follow-up of patients receiving allogeneic stem cell transplant for chronic lymphocytic leukaemia: mixed T-cell chimerism is associated with high relapse risk and inferior survival.
Academic Article	Characteristics, outcomes, prognostic factors and treatment of patients with T-cell prolymphocytic leukemia (T-PLL).
Academic Article	TP53 mutation does not confer a poor outcome in adult patients with acute lymphoblastic leukemia who are treated with frontline hyper-CVAD-based regimens.
Academic Article	A phase I study of moxetumomab pasudotox in adults with relapsed or refractory B-cell acute lymphoblastic leukaemia.
Academic Article	A phase I/II randomized trial of clofarabine or fludarabine added to idarubicin and cytarabine for adults with relapsed or refractory acute myeloid leukemia.
Academic Article	Activation of the B-cell receptor successively activates NF-?B and STAT3 in chronic lymphocytic leukemia cells.
Academic Article	Clinical characteristics and outcomes of previously untreated patients with adult onset T-acute lymphoblastic leukemia and T-lymphoblastic lymphoma with hyper-CVAD based regimens.
Academic Article	Long-term outcomes for patients with chronic lymphocytic leukemia who discontinue ibrutinib.
Academic Article	Outcomes of adults with relapsed or refractory Burkitt and high-grade B-cell leukemia/lymphoma.
Academic Article	Characteristics and outcomes of older patients with secondary acute myeloid leukemia according to treatment approach.
Academic Article	Chlorinated adenosine analogue induces AMPK and autophagy in chronic lymphocytic leukaemia cells during therapy.
Academic Article	Prognostic factors and survival outcomes in patients with chronic myeloid leukemia in blast phase in the tyrosine kinase inhibitor era: Cohort study of 477 patients.
Academic Article	Consolidation treatment with lenalidomide following front-line or salvage chemoimmunotherapy in chronic lymphocytic leukemia.
Academic Article	Co-occurrence of CRLF2-rearranged and Ph+ acute lymphoblastic leukemia: a report of four patients.
Academic Article	The Stromal Microenvironment Modulates Mitochondrial Oxidative Phosphorylation in Chronic Lymphocytic Leukemia Cells.
Academic Article	Phase 1 dose escalation multicenter trial of pracinostat alone and in combination with azacitidine in patients with advanced hematologic malignancies.
Academic Article	Safety and Efficacy of Blinatumomab in Combination With a Tyrosine Kinase Inhibitor for the Treatment of Relapsed Philadelphia Chromosome-positive Leukemia.
Academic Article	Proteomics profiling identifies induction of caveolin-1 in chronic lymphocytic leukemia cells by bone marrow stromal cells.
Academic Article	Ibrutinib modulates the immunosuppressive CLL microenvironment through STAT3-mediated suppression of regulatory B-cell function and inhibition of the PD-1/PD-L1 pathway.
Academic Article	Hairy Cell Leukemia, Version 2.2018, NCCN Clinical Practice Guidelines in Oncology.
Academic Article	Outcome of patients with relapsed/refractory acute lymphoblastic leukemia after blinatumomab failure: No change in the level of CD19 expression.
Academic Article	A randomized phase 2 study of idarubicin and cytarabine with clofarabine or fludarabine in patients with newly diagnosed acute myeloid leukemia.
Academic Article	Acute promyelocytic leukemia in a patient with chronic lymphocytic leukemia-A case report.
Academic Article	Clonal chromosomal abnormalities appearing in Philadelphia chromosome-negative metaphases during CML treatment.
Academic Article	Hyper-CVAD plus nelarabine in newly diagnosed adult T-cell acute lymphoblastic leukemia and T-lymphoblastic lymphoma.
Academic Article	Pharmacodynamics and proteomic analysis of acalabrutinib therapy: similarity of on-target effects to ibrutinib and rationale for combination therapy.
Academic Article	The absolute percent deviation of IGHV mutation rather than a 98% cut-off predicts survival of chronic lymphocytic leukaemia patients treated with fludarabine, cyclophosphamide and rituximab.
Academic Article	Calreticulin as a novel B-cell receptor antigen in chronic lymphocytic leukemia.
Academic Article	Prognostic significance of additional chromosomal abnormalities at the time of diagnosis in patients with chronic myeloid leukemia treated with frontline tyrosine kinase inhibitors.
Academic Article	Characteristics and outcome of chronic myeloid leukemia patients with E255K/V BCR-ABL kinase domain mutations.
Academic Article	Ibrutinib inhibits free fatty acid metabolism in chronic lymphocytic leukemia.
Academic Article	Sustained long-lasting responses after lenalidomide discontinuation in patients with chronic lymphocytic leukemia.
Academic Article	The CXCR4-STAT3-IL-10 Pathway Controls the Immunoregulatory Function of Chronic Lymphocytic Leukemia and Is Modulated by Lenalidomide.
Academic Article	Clinical implications of cancer gene mutations in patients with chronic lymphocytic leukemia treated with lenalidomide.
Academic Article	Single-agent ibrutinib in treatment-na?ve and relapsed/refractory chronic lymphocytic leukemia: a 5-year experience.
Academic Article	Prediction for sustained deep molecular response of BCR-ABL1 levels in patients with chronic myeloid leukemia in chronic phase.
Academic Article	Inotuzumab ozogamicin in combination with low-intensity chemotherapy for older patients with Philadelphia chromosome-negative acute lymphoblastic leukaemia: a single-arm, phase 2 study.
Academic Article	Biological and metabolic effects of IACS-010759, an OxPhos inhibitor, on chronic lymphocytic leukemia cells.
Academic Article	A Pilot Phase II Study of Erlotinib for the Treatment of Patients with Relapsed/Refractory Acute Myeloid Leukemia.
Academic Article	STAT3 is constitutively acetylated on lysine 685 residues in chronic lymphocytic leukemia cells.
Academic Article	A phase II trial of eltrombopag for patients with chronic lymphocytic leukaemia (CLL) and thrombocytopenia.
Academic Article	Comprehensive Safety Analysis of Venetoclax Monotherapy for Patients with Relapsed/Refractory Chronic Lymphocytic Leukemia.
Academic Article	A prospective analysis of symptom burden for patients with chronic myeloid leukemia in chronic phase treated with frontline second- and third-generation tyrosine kinase inhibitors.
Academic Article	Initial Report of a Phase I Study of LY2510924, Idarubicin, and Cytarabine in Relapsed/Refractory Acute Myeloid Leukemia.
Academic Article	Venetoclax for Patients With Chronic Lymphocytic Leukemia With 17p Deletion: Results From the Full Population of a Phase II Pivotal Trial.
Academic Article	STAT3-activated CD36 facilitates fatty acid uptake in chronic lymphocytic leukemia cells.
Academic Article	Serial minimal residual disease (MRD) monitoring during first-line FCR treatment for CLL may direct individualized therapeutic strategies.
Academic Article	Evaluation of 230 patients with relapsed/refractory deletion 17p chronic lymphocytic?leukaemia treated with ibrutinib from 3 clinical trials.
Academic Article	NCCN Guidelines Insights: Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma, Version 2.2019.
Academic Article	Tumour debulking and reduction in predicted risk of tumour lysis syndrome with single-agent ibrutinib in patients with chronic lymphocytic leukaemia.
Academic Article	Venetoclax for chronic lymphocytic leukaemia patients who progress after more than one B-cell receptor pathway inhibitor.
Academic Article	Combination of hyper-CVAD with ponatinib as first-line therapy for patients with Philadelphia chromosome-positive acute lymphoblastic leukaemia: long-term follow-up of a single-centre, phase 2 study.
Academic Article	Targeted multigene deep sequencing of Bruton tyrosine kinase inhibitor-resistant chronic lymphocytic leukemia with disease progression and Richter transformation.
Academic Article	Tolerability and activity of ublituximab, umbralisib, and ibrutinib in patients with chronic lymphocytic leukaemia and non-Hodgkin lymphoma: a phase 1 dose escalation and expansion trial.
Academic Article	Distinguishing thymoma from T-lymphoblastic leukaemia/lymphoma: a case-based evaluation.
Academic Article	Creating novel translation inhibitors to target pro-survival proteins in chronic lymphocytic leukemia.
Academic Article	Cerebral edema secondary to chimeric antigen receptor T-cell immunotherapy.
Academic Article	Randomized trial of ibrutinib vs ibrutinib plus rituximab in patients with chronic lymphocytic leukemia.
Academic Article	Incidence of second malignancies in patients with chronic myeloid leukemia in the era of tyrosine kinase inhibitors.
Academic Article	Phase 1b study of venetoclax-obinutuzumab in previously untreated and relapsed/refractory chronic lymphocytic leukemia.
Academic Article	Utility of positron emission tomography-computed tomography in patients with chronic lymphocytic leukemia following B-cell receptor pathway inhibitor therapy.
Academic Article	Routine sequencing in CLL has prognostic implications and provides new insight into pathogenesis and targeted treatments.
Academic Article	A pilot study of lower doses of ibrutinib in patients with chronic lymphocytic leukemia.
Academic Article	Ofatumumab is safe and effective as front-line treatment in older patients with chronic lymphocytic leukemia and severe co-morbidities, including other malignancies.
Academic Article	Efficacy of venetoclax in relapsed chronic lymphocytic leukemia is influenced by disease and response variables.
Academic Article	PIM kinase inhibitor, AZD1208, inhibits protein translation and induces autophagy in primary chronic lymphocytic leukemia cells.
Academic Article	Efficacy and predictors of response of lenalidomide and rituximab in patients with treatment-naive and relapsed CLL.
Concept	Myeloid Cell Leukemia Sequence 1 Protein
Academic Article	Ibrutinib and Venetoclax for First-Line Treatment of CLL.
Academic Article	Induction of apoptosis by MCL-1 inhibitors in chronic lymphocytic leukemia cells.
Academic Article	Does FCR have the potential to cure a subgroup of patients with chronic lymphocytic leukemia?
Academic Article	Association of gene mutations with time-to-first treatment in 384 treatment-naive chronic lymphocytic leukaemia patients.
Academic Article	Developmental subtypes assessed by DNA methylation-iPLEX forecast the natural history of chronic lymphocytic leukemia.
Academic Article	Targeting BCL2 in Chronic Lymphocytic Leukemia and Other Hematologic Malignancies.
Academic Article	The landscape of genetic mutations in patients with chronic lymphocytic leukaemia and complex karyotype.
Academic Article	Trabectedin Reveals a Strategy of Immunomodulation in Chronic Lymphocytic Leukemia.
Academic Article	Minimal residual disease undetectable by next-generation sequencing predicts improved outcome in CLL after chemoimmunotherapy.
Academic Article	Mitochondrial Reprogramming Underlies Resistance to BCL-2 Inhibition in Lymphoid Malignancies.
Academic Article	Ublituximab and umbralisib in relapsed/refractory B-cell non-Hodgkin lymphoma and chronic lymphocytic leukemia.
Academic Article	First report of clinical response to venetoclax combination with pentostatin in T-cell-prolymphocytic leukemia (T-PLL).
Academic Article	STAT3-Induced Wnt5a Provides Chronic Lymphocytic Leukemia Cells with Survival Advantage.
Academic Article	The early achievement of measurable residual disease negativity in the treatment of adults with Philadelphia-negative B-cell acute lymphoblastic leukemia is a strong predictor for survival.
Academic Article	Evolving Strategies in First-Line Chronic Lymphocytic Leukemia: Is There a Role for Chemoimmunotherapy?
Academic Article	The BET inhibitor GS-5829 targets chronic lymphocytic leukemia cells and their supportive microenvironment.
Academic Article	Acalabrutinib monotherapy in patients with relapsed/refractory chronic lymphocytic leukemia: updated phase 2 results.
Academic Article	Achieving complete remission in CLL patients treated with ibrutinib: clinical significance and predictive factors.
Academic Article	AMG-176, an Mcl-1 Antagonist, Shows Preclinical Efficacy in Chronic Lymphocytic Leukemia.
Academic Article	Tumour lysis syndrome in patients with chronic lymphocytic leukaemia treated with BCL-2 inhibitors: risk factors, prophylaxis, and treatment recommendations.
Academic Article	Use of CAR-Transduced Natural Killer Cells in CD19-Positive Lymphoid Tumors.
Academic Article	Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma, Version 4.2020, NCCN Clinical Practice Guidelines in Oncology.
Academic Article	How I manage CLL with venetoclax-based treatments.
Academic Article	Phase 2 study of hyper-CMAD with liposomal vincristine for patients with newly diagnosed acute lymphoblastic leukemia.
Academic Article	Ibrutinib Treatment for First-Line and Relapsed/Refractory Chronic Lymphocytic Leukemia: Final Analysis of the Pivotal Phase Ib/II PCYC-1102 Study.
Academic Article	International prognostic score for asymptomatic early-stage chronic lymphocytic leukemia.
Academic Article	Clinical value of event-free survival in acute myeloid leukemia.
Academic Article	Acalabrutinib with or without obinutuzumab versus chlorambucil and obinutuzmab for treatment-naive chronic lymphocytic leukaemia (ELEVATE TN): a randomised, controlled, phase 3 trial.
Academic Article	Treating Leukemia in the Time of COVID-19.
Academic Article	Incidence and characterization of fungal infections in chronic lymphocytic leukemia patients receiving ibrutinib.
Academic Article	Phase II trial of CPX-351 in patients with acute myeloid leukemia at high risk for induction mortality.
Academic Article	Survivorship in AML - a landmark analysis on the outcomes of acute myelogenous leukemia patients after maintaining complete remission for at least 3 years.
Academic Article	Integrated Mechanistic Model of Minimal Residual Disease Kinetics With Venetoclax Therapy in Chronic Lymphocytic Leukemia.
Academic Article	Incidental Richter transformation in chronic lymphocytic leukemia patients during temporary interruption of ibrutinib.
Academic Article	Translocation t(1;19)(q23;p13) in adult acute lymphoblastic leukemia - a distinct subtype with favorable prognosis.
Academic Article	Complete remission in refractory acute lymphoblastic leukemia using blinatumomab after failure of response to CD-19 chimeric antigen receptor T-cell therapy.
Academic Article	CXCL13 plasma levels function as a biomarker for disease activity in patients with chronic lymphocytic leukemia.
Academic Article	The LEukemia Artificial Intelligence Program (LEAP) in chronic myeloid leukemia in chronic phase: A model to improve patient outcomes.
Academic Article	Expression of BCL2 alternative proteins and association with outcome in CLL patients treated with venetoclax.
Academic Article	Triplet therapy with venetoclax, FLT3 inhibitor and decitabine for FLT3-mutated acute myeloid leukemia.
Academic Article	Clinical Outcomes of Patients With Chronic Myeloid Leukemia With Concurrent Core Binding Factor Rearrangement and Philadelphia Chromosome.
Academic Article	Pirtobrutinib in relapsed or refractory B-cell malignancies (BRUIN): a phase 1/2 study.
Academic Article	The multi-kinase inhibitor TG02 induces apoptosis and blocks B-cell receptor signaling in chronic lymphocytic leukemia through dual mechanisms of action.
Academic Article	STAT3 induces the expression of GLI1 in chronic lymphocytic leukemia cells.
Academic Article	KTE-X19 anti-CD19 CAR T-cell therapy in adult relapsed/refractory acute lymphoblastic leukemia: ZUMA-3 phase 1 results.
Academic Article	Autologous CD33-CAR-T cells for treatment of relapsed/refractory acute myelogenous leukemia.
Academic Article	Acalabrutinib in treatment-naive chronic lymphocytic leukemia.
Academic Article	Prognostic factors for progression in patients with Philadelphia chromosome-positive acute lymphoblastic leukemia in complete molecular response within 3 months of therapy with tyrosine kinase inhibitors.
Academic Article	A phase I/II study of the combination of quizartinib with azacitidine or low-dose cytarabine for the treatment of patients with acute myeloid leukemia and myelodysplastic syndrome.
Academic Article	Ibrutinib, fludarabine, cyclophosphamide, and obinutuzumab (iFCG) regimen for chronic lymphocytic leukemia (CLL) with mutated IGHV and without TP53 aberrations.
Academic Article	Ibrutinib Plus Venetoclax for First-line Treatment of Chronic Lymphocytic Leukemia: A Nonrandomized Phase 2 Trial.
Academic Article	KTE-X19 for relapsed or refractory adult B-cell acute lymphoblastic leukaemia: phase 2 results of the single-arm, open-label, multicentre ZUMA-3 study.
Academic Article	Measurable residual disease in chronic lymphocytic leukemia: expert review and consensus recommendations.
Academic Article	Vecabrutinib inhibits B-cell receptor signal transduction in chronic lymphocytic leukemia cell types with wild-type or mutant Bruton tyrosine kinase.
Academic Article	Ibrutinib induces durable remissions in treatment-na?ve patients with CLL and 17p deletion and/or TP53 mutations.
Academic Article	The cure of leukemia through the optimist's prism.
Academic Article	Ibrutinib Plus Venetoclax for First-Line Treatment of Chronic Lymphocytic Leukemia: Primary Analysis Results From the Minimal Residual Disease Cohort of the Randomized Phase II CAPTIVATE Study.
Academic Article	RPPA-based proteomics recognizes distinct epigenetic signatures in chronic lymphocytic leukemia with clinical consequences.
Academic Article	Value of measurable residual disease monitoring in patients with acute promyelocytic leukemia in the era of frontline 'chemotherapy-free' therapy.
Academic Article	Phase 1 TRANSCEND CLL 004 study of lisocabtagene maraleucel in patients with relapsed/refractory CLL or SLL.
Academic Article	Acalabrutinib monotherapy for treatment of chronic lymphocytic leukaemia (ACE-CL-001): analysis of the Richter transformation cohort of an open-label, single-arm, phase 1-2 study.
Academic Article	The Role of BTK Inhibition in the Treatment of Chronic Lymphocytic Leukemia: A Clinical View.
Academic Article	Non-coding NOTCH1 mutations in chronic lymphocytic leukemia negatively impact prognosis.
Academic Article	Efficacy and safety in a 4-year follow-up of the ELEVATE-TN study comparing acalabrutinib with or without obinutuzumab versus obinutuzumab plus chlorambucil in treatment-na?ve chronic lymphocytic leukemia.
Academic Article	The TKI Era in Chronic Leukemias.
Academic Article	Clinical outcome of allogeneic stem cell transplantation in patients with B-cell lymphoid malignancies following treatment with targeted small molecule inhibitors.
Academic Article	Lenalidomide enhances CD23.CAR T cell therapy in chronic lymphocytic leukemia.
Academic Article	Dismal outcomes of patients with relapsed/refractory Philadelphia chromosome-negative B-cell acute lymphoblastic leukemia after failure of both inotuzumab ozogamicin and blinatumomab.
Academic Article	Targeting Mcl-1 by AMG-176 During Ibrutinib and Venetoclax Therapy in Chronic Lymphocytic Leukemia.
Academic Article	Activation and expansion of T-follicular helper cells in chronic lymphocytic leukemia nurselike cell co-cultures.
Academic Article	Landscape of NOTCH1 mutations and co-occurring biomarker alterations in chronic lymphocytic leukemia.
Academic Article	Cyclin-dependent kinase inhibitor fadraciclib (CYC065) depletes anti-apoptotic protein and synergizes with venetoclax in primary chronic lymphocytic leukemia cells.
Academic Article	STAT3 Activates the Pentraxin 3 Gene in Chronic Lymphocytic Leukemia Cells.
Academic Article	Pirtobrutinib inhibits wild-type and mutant Bruton's tyrosine kinase-mediated signaling in chronic lymphocytic leukemia.
Academic Article	TP53-altered chronic lymphocytic leukemia treated with firstline Bruton's tyrosine kinase inhibitor-based therapy: A retrospective analysis.
Academic Article	NCCN Guidelines? Insights: Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma, Version 3.2022.
Academic Article	High-Risk Acute Myeloid Leukemia: A Pediatric Prospective.
Academic Article	A review of the incidence of tumor lysis syndrome in patients with chronic lymphocytic leukemia treated with venetoclax and debulking strategies.
Academic Article	A phase two study of high dose blinatumomab in Richter's syndrome.
Academic Article	Two-year follow-up of KTE-X19 in patients with relapsed or refractory adult B-cell acute lymphoblastic leukemia in ZUMA-3 and its contextualization with SCHOLAR-3, an external historical control study.
Academic Article	Frontline combination of ponatinib and hyper-CVAD in Philadelphia chromosome-positive acute lymphoblastic leukemia: 80-months follow-up results.
Academic Article	Effective Tumor Debulking with Ibrutinib Before Initiation of Venetoclax: Results from the CAPTIVATE Minimal Residual Disease and Fixed-Duration Cohorts.
Academic Article	Evolutionary history of transformation from chronic lymphocytic leukemia to Richter syndrome.
Academic Article	A phase 2 study of nivolumab combined with ibrutinib in patients with diffuse large B-cell Richter transformation of CLL.
Academic Article	Utility of measurable residual disease for predicting treatment outcomes with BCR- and BCL2-Targeted therapies in patients with CLL.
Academic Article	Mechanisms of MCL-1 Protein Stability Induced by MCL-1 Antagonists in B-Cell Malignancies.
Academic Article	Immunophenotypic and genomic landscape of Richter transformation diffuse large B-cell lymphoma.
Academic Article	Reverse Phase Protein Array Profiling Identifies Recurrent Protein Expression Patterns of DNA Damage-Related Proteins across Acute and Chronic Leukemia: Samples from Adults and the Children's Oncology Group.
Academic Article	Prognostication of DNA Damage Response Protein Expression Patterns in Chronic Lymphocytic Leukemia.
Academic Article	Long-term outcomes in patients with chronic lymphocytic leukemia treated with ibrutinib: Focus on hypertension and cardiovascular toxicity.
Academic Article	Venetoclax consolidation in high-risk CLL treated with ibrutinib for =1 year achieves a high rate of undetectable MRD.
Academic Article	Mini-hyper-CVD plus inotuzumab ozogamicin, with or without blinatumomab, in the subgroup of older patients with newly diagnosed Philadelphia chromosome-negative B-cell acute lymphocytic leukaemia: long-term results of an open-label phase 2 trial.
Academic Article	Incidence of major bleeding in patients with chronic lymphocytic leukemia receiving ibrutinib and therapeutic anticoagulation.
Academic Article	Outcomes in Patients with High-Risk Features after Fixed-Duration Ibrutinib plus Venetoclax: Phase II CAPTIVATE Study in First-Line Chronic Lymphocytic Leukemia.
Academic Article	Pirtobrutinib after a Covalent BTK Inhibitor in Chronic Lymphocytic Leukemia.
Academic Article	Geographic Disparity of Outcome in Patients With Cancer Over Decades: The Surveillance, Epidemiology, and End Results.
Academic Article	Impact of prior therapies and subsequent transplantation on outcomes in adult patients with relapsed or refractory B-cell acute lymphoblastic leukemia treated with brexucabtagene autoleucel in ZUMA-3.
Academic Article	Global miRNA profiling reveals key molecules that contribute to different chronic lymphocytic leukemia incidences in Asian and Western populations.
Academic Article	A phase 1/2 study of mini-hyper-CVD plus venetoclax in patients with relapsed/refractory acute lymphoblastic leukemia.
Academic Article	Six-year follow-up and subgroup analyses of a phase 2 trial of venetoclax for del(17p) chronic lymphocytic leukemia.
Academic Article	Ibrutinib Plus Venetoclax for First-Line Chronic Lymphocytic Leukemia Treatment.
Academic Article	A multicenter study of venetoclax-based treatment for patients with Richter transformation of chronic lymphocytic leukemia.

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