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A medicinal chemistry perspective for targeting histone H3 lysine-79 methyltransferase DOT1L.
Academic Article
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Application of NMR spectroscopy in medicinal chemistry and drug discovery.
Academic Article
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Bioorganic and Medicinal Chemistry Letters
Academic Article
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Bioorganic and Medicinal Chemistry Letters
Academic Article
Why?
Chemistry, Pharmaceutical
Concept
Why?
LI, XIN
Person
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Case-based studies in teaching medicinal chemistry in PharmD curriculum: Perspectives of students, faculty, and pharmacists from academia.
Academic Article
Why?
Investigation of antibody disulfide reduction and re-oxidation and impact to biological activities.
Academic Article
Why?
Potent and selective phosphopeptide mimetic prodrugs targeted to the Src homology 2 (SH2) domain of signal transducer and activator of transcription 3.
Academic Article
Why?
Small-molecule activators of insulin-degrading enzyme discovered through high-throughput compound screening.
Academic Article
Why?
Structure-activity relationship, kinetic mechanism, and selectivity for a new class of ubiquitin C-terminal hydrolase-L1 (UCH-L1) inhibitors.
Academic Article
Why?
Synthesis of fused imidazoles, pyrroles, and indoles with a defined stereocenter a to nitrogen utilizing Mitsunobu alkylation followed by palladium-catalyzed cyclization.
Academic Article
Why?
SONG, YONGCHENG
Person
Why?
Novel inhibitors of 1-deoxy-D-xylulose-5-phosphate reductoisomerase (DXR)
Grant
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CUNY, GREG
Person
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