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DENNIS VILLAREAL to Aged

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This is a "connection" page, showing publications DENNIS VILLAREAL has written about Aged.
DENNIS VILLAREAL
Connection Strength
2.453
Aged
  1. Exercise but not diet-induced weight loss decreases skeletal muscle inflammatory gene expression in frail obese elderly persons. J Appl Physiol (1985). 2008 Aug; 105(2):473-8.
    View in: PubMed
    Score: 0.080
  2. High-Fidelity Finite Element Modeling Technique to Improve Sensitivity to Bone Tissue Changes of Older Adults with Obesity undergoing Intensive Lifestyle Intervention. Ann Biomed Eng. 2025 Sep; 53(9):2359-2371.
    View in: PubMed
    Score: 0.065
  3. Effect of aerobic or resistance exercise, or both on insulin secretion, ciliary neurotrophic factor, and insulin-like growth factor-1 in dieting older adults with obesity. Clin Nutr. 2025 Aug; 51:50-62.
    View in: PubMed
    Score: 0.065
  4. Metabolic Effects of Testosterone Added to Intensive Lifestyle Intervention in Older Men With Obesity and Hypogonadism. J Clin Endocrinol Metab. 2025 Feb 18; 110(3):e814-e826.
    View in: PubMed
    Score: 0.063
  5. Testosterone Modulation of Muscle Transcriptomic Profile During Lifestyle Therapy in Older Men with Obesity and Hypogonadism. J Cachexia Sarcopenia Muscle. 2025 Feb; 16(1):e13697.
    View in: PubMed
    Score: 0.063
  6. What weight changes really happened during COVID-19 among older adults? J Nutr Health Aging. 2024 04; 28(4):100221.
    View in: PubMed
    Score: 0.060
  7. Should the Incretin hype be the same for older adults: Promise + cautions. J Am Geriatr Soc. 2024 Jul; 72(7):2266-2268.
    View in: PubMed
    Score: 0.059
  8. Indices of sarcopenic obesity are important predictors of finite element analysis-derived bone strength in older adults with obesity. Front Endocrinol (Lausanne). 2023; 14:1279321.
    View in: PubMed
    Score: 0.058
  9. Targeting Energy Intake and Circadian Biology to Engage Mechanisms of Aging in Older Adults With Obesity: Calorie Restriction and Time-Restricted Eating. J Gerontol A Biol Sci Med Sci. 2023 06 16; 78(Suppl 1):79-85.
    View in: PubMed
    Score: 0.056
  10. Weight strategy in older adults with obesity: calorie restriction or not? Curr Opin Clin Nutr Metab Care. 2023 01 01; 26(1):17-22.
    View in: PubMed
    Score: 0.054
  11. Lifestyle Intervention Strategy to Treat Diabetes in Older Adults: A Randomized Controlled Trial. Diabetes Care. 2022 09 01; 45(9):1943-1952.
    View in: PubMed
    Score: 0.053
  12. Effect of Aerobic or Resistance Exercise, or Both, on Intermuscular and Visceral Fat and Physical and Metabolic Function in Older Adults With Obesity While Dieting. J Gerontol A Biol Sci Med Sci. 2022 01 07; 77(1):131-139.
    View in: PubMed
    Score: 0.051
  13. Truncal Fat and Frailty Are Important Predictors of Cognitive Performance among Aging Adults with Obesity. J Nutr Health Aging. 2022; 26(5):425-429.
    View in: PubMed
    Score: 0.051
  14. Effect of Diet, Exercise, or Both on Biological Age and Healthy Aging in Older Adults with Obesity: Secondary Analysis of a Randomized Controlled Trial. J Nutr Health Aging. 2022; 26(6):552-557.
    View in: PubMed
    Score: 0.051
  15. Cognitive response to testosterone replacement added to intensive lifestyle intervention in older men with obesity and hypogonadism: prespecified secondary analyses of a randomized clinical trial. Am J Clin Nutr. 2021 11 08; 114(5):1590-1599.
    View in: PubMed
    Score: 0.050
  16. Aging, obesity, sarcopenia and the effect of diet and exercise intervention. Exp Gerontol. 2021 11; 155:111561.
    View in: PubMed
    Score: 0.050
  17. Testosterone Replacement Therapy Added to Intensive Lifestyle Intervention in Older Men With Obesity and Hypogonadism. J Clin Endocrinol Metab. 2021 03 08; 106(3):e1096-e1110.
    View in: PubMed
    Score: 0.048
  18. Effect of Aerobic or Resistance Exercise, or Both, on Bone Mineral Density and Bone Metabolism in Obese Older Adults While Dieting: A Randomized Controlled Trial. J Bone Miner Res. 2020 03; 35(3):430-439.
    View in: PubMed
    Score: 0.044
  19. Aerobic Plus Resistance Exercise in Obese Older Adults Improves Muscle Protein Synthesis and Preserves Myocellular Quality Despite Weight Loss. Cell Metab. 2019 08 06; 30(2):261-273.e6.
    View in: PubMed
    Score: 0.043
  20. Weight Loss-Induced Reduction of Bone Mineral Density in Older Adults with Obesity. J Nutr Gerontol Geriatr. 2019 Jan-Mar; 38(1):100-114.
    View in: PubMed
    Score: 0.042
  21. Therapeutic and lifestyle approaches to obesity in older persons. Curr Opin Clin Nutr Metab Care. 2019 01; 22(1):30-36.
    View in: PubMed
    Score: 0.041
  22. Sarcopenic obesity in older adults: aetiology, epidemiology and treatment strategies. Nat Rev Endocrinol. 2018 09; 14(9):513-537.
    View in: PubMed
    Score: 0.040
  23. Effect of Weight Loss, Exercise, or Both on Undercarboxylated Osteocalcin and Insulin Secretion in Frail, Obese Older Adults. Oxid Med Cell Longev. 2017; 2017:4807046.
    View in: PubMed
    Score: 0.038
  24. Aerobic or Resistance Exercise, or Both, in Dieting Obese Older Adults. N Engl J Med. 2017 05 18; 376(20):1943-1955.
    View in: PubMed
    Score: 0.037
  25. Effects of Weight Loss on Lean Mass, Strength, Bone, and Aerobic Capacity. Med Sci Sports Exerc. 2017 01; 49(1):206-217.
    View in: PubMed
    Score: 0.036
  26. Circulating cytokines as determinants of weight loss-induced improvements in insulin sensitivity. Endocrine. 2017 Jan; 55(1):153-164.
    View in: PubMed
    Score: 0.035
  27. Effects of matched weight loss from calorie restriction, exercise, or both on cardiovascular disease risk factors: a randomized intervention trial. Am J Clin Nutr. 2016 Sep; 104(3):576-86.
    View in: PubMed
    Score: 0.035
  28. Effect of Lifestyle Intervention on the Hormonal Profile of Frail, Obese Older Men. J Nutr Health Aging. 2016 Mar; 20(3):334-40.
    View in: PubMed
    Score: 0.034
  29. Physical Exercise as Therapy for Frailty. Nestle Nutr Inst Workshop Ser. 2015; 83:83-92.
    View in: PubMed
    Score: 0.033
  30. Calorie Restriction and Matched Weight Loss From Exercise: Independent and Additive Effects on Glucoregulation and the Incretin System in Overweight Women and Men. Diabetes Care. 2015 Jul; 38(7):1253-62.
    View in: PubMed
    Score: 0.032
  31. Effect of weight loss, exercise, or both on cognition and quality of life in obese older adults. Am J Clin Nutr. 2014 Jul; 100(1):189-98.
    View in: PubMed
    Score: 0.030
  32. Sarcopenic obesity: how do we treat it? Curr Opin Endocrinol Diabetes Obes. 2013 Oct; 20(5):412-9.
    View in: PubMed
    Score: 0.029
  33. Changes in thigh muscle volume predict bone mineral density response to lifestyle therapy in frail, obese older adults. Osteoporos Int. 2014 Feb; 25(2):551-8.
    View in: PubMed
    Score: 0.028
  34. Weight loss, exercise or both and cardiometabolic risk factors in obese older adults: results of a randomized controlled trial. Int J Obes (Lond). 2014 Mar; 38(3):423-31.
    View in: PubMed
    Score: 0.028
  35. Weight loss in obese adults 65years and older: a review of the controversy. Exp Gerontol. 2013 Oct; 48(10):1054-61.
    View in: PubMed
    Score: 0.028
  36. Long-term maintenance of weight loss after lifestyle intervention in frail, obese older adults. J Nutr Health Aging. 2013 Jan; 17(1):3-7.
    View in: PubMed
    Score: 0.027
  37. Weight loss in obese older adults increases serum sclerostin and impairs hip geometry but both are prevented by exercise training. J Bone Miner Res. 2012 May; 27(5):1215-21.
    View in: PubMed
    Score: 0.026
  38. Exercise training in obese older adults prevents increase in bone turnover and attenuates decrease in hip bone mineral density induced by weight loss despite decline in bone-active hormones. J Bone Miner Res. 2011 Dec; 26(12):2851-9.
    View in: PubMed
    Score: 0.025
  39. Effect of weight loss on the rate of muscle protein synthesis during fasted and fed conditions in obese older adults. Obesity (Silver Spring). 2012 Sep; 20(9):1780-6.
    View in: PubMed
    Score: 0.025
  40. Weight loss, exercise, or both and physical function in obese older adults. N Engl J Med. 2011 Mar 31; 364(13):1218-29.
    View in: PubMed
    Score: 0.024
  41. Regular multicomponent exercise increases physical fitness and muscle protein anabolism in frail, obese, older adults. Obesity (Silver Spring). 2011 Feb; 19(2):312-8.
    View in: PubMed
    Score: 0.023
  42. Diet and exercise interventions reduce intrahepatic fat content and improve insulin sensitivity in obese older adults. Obesity (Silver Spring). 2009 Dec; 17(12):2162-8.
    View in: PubMed
    Score: 0.021
  43. Dehydroepiandrosterone replacement therapy in older adults: 1- and 2-y effects on bone. Am J Clin Nutr. 2009 May; 89(5):1459-67.
    View in: PubMed
    Score: 0.021
  44. Exercise attenuates the weight-loss-induced reduction in muscle mass in frail obese older adults. Med Sci Sports Exerc. 2008 Jul; 40(7):1213-9.
    View in: PubMed
    Score: 0.020
  45. Weight-loss therapy improves endurance capacity in obese older adults. J Am Geriatr Soc. 2008 Jun; 56(6):1157-9.
    View in: PubMed
    Score: 0.020
  46. Weight loss therapy improves pancreatic endocrine function in obese older adults. Obesity (Silver Spring). 2008 Jun; 16(6):1349-54.
    View in: PubMed
    Score: 0.020
  47. Effect of weight loss and exercise therapy on bone metabolism and mass in obese older adults: a one-year randomized controlled trial. J Clin Endocrinol Metab. 2008 Jun; 93(6):2181-7.
    View in: PubMed
    Score: 0.020
  48. Effects of soy protein isolate and moderate exercise on bone turnover and bone mineral density in postmenopausal women. Menopause. 2007 May-Jun; 14(3 Pt 1):481-8.
    View in: PubMed
    Score: 0.018
  49. Effect of lifestyle intervention on metabolic coronary heart disease risk factors in obese older adults. Am J Clin Nutr. 2006 Dec; 84(6):1317-23.
    View in: PubMed
    Score: 0.018
  50. DHEA enhances effects of weight training on muscle mass and strength in elderly women and men. Am J Physiol Endocrinol Metab. 2006 Nov; 291(5):E1003-8.
    View in: PubMed
    Score: 0.017
  51. Effect of weight loss and exercise on frailty in obese older adults. Arch Intern Med. 2006 Apr 24; 166(8):860-6.
    View in: PubMed
    Score: 0.017
  52. Obesity in older adults: technical review and position statement of the American Society for Nutrition and NAASO, The Obesity Society. Am J Clin Nutr. 2005 Nov; 82(5):923-34.
    View in: PubMed
    Score: 0.017
  53. Obesity in older adults: technical review and position statement of the American Society for Nutrition and NAASO, The Obesity Society. Obes Res. 2005 Nov; 13(11):1849-63.
    View in: PubMed
    Score: 0.017
  54. BIO101 in Sarcopenic Seniors at Risk of Mobility Disability: Results of a Double-Blind Randomised Interventional Phase 2b Trial. J Cachexia Sarcopenia Muscle. 2025 Apr; 16(2):e13750.
    View in: PubMed
    Score: 0.016
  55. Global consensus on optimal exercise recommendations for enhancing healthy longevity in older adults (ICFSR). J Nutr Health Aging. 2025 Jan; 29(1):100401.
    View in: PubMed
    Score: 0.016
  56. Effect of DHEA on abdominal fat and insulin action in elderly women and men: a randomized controlled trial. JAMA. 2004 Nov 10; 292(18):2243-8.
    View in: PubMed
    Score: 0.016
  57. A PRDM16-driven signal regulates body composition in testosterone-treated hypogonadal men. Front Endocrinol (Lausanne). 2024; 15:1426175.
    View in: PubMed
    Score: 0.015
  58. Physical frailty and body composition in obese elderly men and women. Obes Res. 2004 Jun; 12(6):913-20.
    View in: PubMed
    Score: 0.015
  59. Effects of exercise training on bone mineral density in frail older women and men: a randomised controlled trial. Age Ageing. 2004 May; 33(3):309-12.
    View in: PubMed
    Score: 0.015
  60. Depressive Symptoms are Associated With C-Reactive Protein in Older Adults With Obesity. J Geriatr Psychiatry Neurol. 2024 Jul; 37(4):332-338.
    View in: PubMed
    Score: 0.015
  61. Clinical outcomes of possible versus probable Alzheimer's disease. Neurology. 2003 Sep 09; 61(5):661-7.
    View in: PubMed
    Score: 0.014
  62. Effects of exercise training added to ongoing hormone replacement therapy on bone mineral density in frail elderly women. J Am Geriatr Soc. 2003 Jul; 51(7):985-90.
    View in: PubMed
    Score: 0.014
  63. Circulating osteogenic progenitors and osteoclast precursors are associated with long-term glycemic control, sex steroids, and visceral adipose tissue in men with type 2 diabetes mellitus. Front Endocrinol (Lausanne). 2022; 13:936159.
    View in: PubMed
    Score: 0.013
  64. Outcomes addressed in randomized controlled lifestyle intervention trials in community-dwelling older people with (sarcopenic) obesity-An evidence map. Obes Rev. 2022 10; 23(10):e13497.
    View in: PubMed
    Score: 0.013
  65. Baseline Testosterone Predicts Body Composition and Metabolic Response to Testosterone Therapy. Front Endocrinol (Lausanne). 2022; 13:915309.
    View in: PubMed
    Score: 0.013
  66. Hemoglobin A1c Threshold for Reduction in Bone Turnover in Men With Type 2 Diabetes Mellitus. Front Endocrinol (Lausanne). 2021; 12:788107.
    View in: PubMed
    Score: 0.013
  67. Bone mineral density response to estrogen replacement in frail elderly women: a randomized controlled trial. JAMA. 2001 Aug 15; 286(7):815-20.
    View in: PubMed
    Score: 0.012
  68. Testosterone Therapy Effects on Bone Mass and Turnover in Hypogonadal Men with Type 2 Diabetes. J Clin Endocrinol Metab. 2021 07 13; 106(8):e3058-e3068.
    View in: PubMed
    Score: 0.012
  69. In Men With Obesity, T2DM Is Associated With Poor Trabecular Microarchitecture and Bone Strength and Low Bone Turnover. J Clin Endocrinol Metab. 2021 04 23; 106(5):1362-1376.
    View in: PubMed
    Score: 0.012
  70. International Exercise Recommendations in Older Adults (ICFSR): Expert Consensus Guidelines. J Nutr Health Aging. 2021; 25(7):824-853.
    View in: PubMed
    Score: 0.012
  71. Plasma Dehydroepiandrosterone Sulfate and Cardiovascular Disease Risk in Older Men and Women. J Clin Endocrinol Metab. 2020 12 01; 105(12).
    View in: PubMed
    Score: 0.012
  72. Effects of DHEA replacement on bone mineral density and body composition in elderly women and men. Clin Endocrinol (Oxf). 2000 Nov; 53(5):561-8.
    View in: PubMed
    Score: 0.012
  73. Effective SLOPE: EffectS of Lifestyle interventions in Older PEople with obesity: a systematic review and network meta-analysis protocol. BMJ Open. 2020 10 07; 10(10):e038330.
    View in: PubMed
    Score: 0.012
  74. Aromatase Inhibitors Plus Weight Loss Improves the Hormonal Profile of Obese Hypogonadal Men Without Causing Major Side Effects. Front Endocrinol (Lausanne). 2020; 11:277.
    View in: PubMed
    Score: 0.011
  75. Bone and body composition response to testosterone therapy vary according to polymorphisms in the CYP19A1 gene. Endocrine. 2019 09; 65(3):692-706.
    View in: PubMed
    Score: 0.011
  76. Sex-specific effects of dehydroepiandrosterone (DHEA) on bone mineral density and body composition: A pooled analysis of four clinical trials. Clin Endocrinol (Oxf). 2019 02; 90(2):293-300.
    View in: PubMed
    Score: 0.010
  77. Adipocytes ESR1 Expression, Body Fat and Response to Testosterone Therapy in Hypogonadal Men Vary According to Estradiol Levels. Nutrients. 2018 Sep 04; 10(9).
    View in: PubMed
    Score: 0.010
  78. Designing Drug Trials for Frailty: ICFSR Task Force 2018. J Frailty Aging. 2018; 7(3):150-154.
    View in: PubMed
    Score: 0.010
  79. International Clinical Practice Guidelines for Sarcopenia (ICFSR): Screening, Diagnosis and Management. J Nutr Health Aging. 2018; 22(10):1148-1161.
    View in: PubMed
    Score: 0.010
  80. Hypogonadal Men with Higher Body Mass Index have Higher Bone Density and Better Bone Quality but Reduced Muscle Density. Calcif Tissue Int. 2017 12; 101(6):602-611.
    View in: PubMed
    Score: 0.009
  81. Hypogonadal men with type 2 diabetes mellitus have smaller bone size and lower bone turnover. Bone. 2017 06; 99:14-19.
    View in: PubMed
    Score: 0.009
  82. Reversible States of Physical and/or Cognitive Dysfunction: A 9-Year Longitudinal Study. J Nutr Health Aging. 2017; 21(3):271-275.
    View in: PubMed
    Score: 0.009
  83. High aromatase activity in hypogonadal men is associated with higher spine bone mineral density, increased truncal fat and reduced lean mass. Eur J Endocrinol. 2015 Aug; 173(2):167-74.
    View in: PubMed
    Score: 0.008
  84. Trophic factors in aging. Should older people receive hormonal replacement therapy? Drugs Aging. 1994 Jun; 4(6):492-509.
    View in: PubMed
    Score: 0.008
  85. Increasing adiposity is associated with higher adipokine levels and lower bone mineral density in obese older adults. J Clin Endocrinol Metab. 2014 Sep; 99(9):3290-7.
    View in: PubMed
    Score: 0.008
  86. Sexually dimorphic patterns of nutritional intake and eating behaviors in community-dwelling older adults with normal and slow gait speed. J Nutr Health Aging. 2014 Mar; 18(3):228-33.
    View in: PubMed
    Score: 0.007
  87. Dehydroepiandrosterone replacement therapy in older adults improves indices of arterial stiffness. Aging Cell. 2012 Oct; 11(5):876-84.
    View in: PubMed
    Score: 0.007
  88. Muscle protein synthesis response to exercise training in obese, older men and women. Med Sci Sports Exerc. 2012 Jul; 44(7):1259-66.
    View in: PubMed
    Score: 0.007
  89. Effect of estrogen and calcitonin on vertebral bone density and vertebral height in osteoporotic women. Osteoporos Int. 1992 Mar; 2(2):70-3.
    View in: PubMed
    Score: 0.006
  90. Cognitive and neural correlates of aerobic fitness in obese older adults. Exp Aging Res. 2012; 38(2):131-45.
    View in: PubMed
    Score: 0.006
  91. Dehydroepiandrosterone (DHEA) replacement decreases insulin resistance and lowers inflammatory cytokines in aging humans. Aging (Albany NY). 2011 May; 3(5):533-42.
    View in: PubMed
    Score: 0.006
  92. Subclinical vitamin D deficiency in postmenopausal women with low vertebral bone mass. J Clin Endocrinol Metab. 1991 Mar; 72(3):628-34.
    View in: PubMed
    Score: 0.006
  93. Endothelial function after high-sugar-food ingestion improves with endurance exercise performed on the previous day. Am J Clin Nutr. 2008 Jul; 88(1):51-7.
    View in: PubMed
    Score: 0.005
  94. Differences in muscle protein synthesis and anabolic signaling in the postabsorptive state and in response to food in 65-80 year old men and women. PLoS One. 2008 Mar 26; 3(3):e1875.
    View in: PubMed
    Score: 0.005
  95. Aerobic power and insulin action improve in response to endurance exercise training in healthy 77-87 yr olds. J Appl Physiol (1985). 2005 Jan; 98(1):40-5.
    View in: PubMed
    Score: 0.004
  96. Effect of CYP1A1 gene polymorphisms on estrogen metabolism and bone density. J Bone Miner Res. 2005 Feb; 20(2):232-9.
    View in: PubMed
    Score: 0.004
  97. Absence of left ventricular and arterial adaptations to exercise in octogenarians. J Appl Physiol (1985). 2004 Nov; 97(5):1654-9.
    View in: PubMed
    Score: 0.004
  98. Attenuation of cardiovascular adaptations to exercise in frail octogenarians. J Appl Physiol (1985). 2003 Nov; 95(5):1781-8.
    View in: PubMed
    Score: 0.004
  99. Peak exercise stroke volume: associations with cardiac structure and diastolic function. J Appl Physiol (1985). 2003 Mar; 94(3):1108-14.
    View in: PubMed
    Score: 0.003
  100. Estrogen status and bone mass in the premenopausal period: is osteoporosis a developmental disease? J Endocrinol Invest. 1993 Nov; 16(10):829-39.
    View in: PubMed
    Score: 0.002
  101. Dietary L-lysine and calcium metabolism in humans. Nutrition. 1992 Nov-Dec; 8(6):400-5.
    View in: PubMed
    Score: 0.002
  102. Paget's disease of bone affecting a single vertebra: clinical, radiologic, and histopathologic correlations. Calcif Tissue Int. 1992 Feb; 50(2):115-7.
    View in: PubMed
    Score: 0.002
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