Connection

Co-Authors

This is a "connection" page, showing publications co-authored by DAMIAN YOUNG and KEVIN MACKENZIE.
Connection Strength

1.903
  1. Chemical Catalysis Guides Structural Identification for the Major In Vivo Metabolite of the BET Inhibitor JQ1. ACS Med Chem Lett. 2024 Jan 11; 15(1):107-115.
    View in: PubMed
    Score: 0.234
  2. A Concise Synthetic Method for Constructing 3-Substituted Piperazine-2-Acetic Acid Esters from 1,2-Diamines. Molecules. 2022 May 25; 27(11).
    View in: PubMed
    Score: 0.209
  3. Discovery of small molecules targeting the tandem tudor domain of the epigenetic factor UHRF1 using fragment-based ligand discovery. Sci Rep. 2021 01 13; 11(1):1121.
    View in: PubMed
    Score: 0.190
  4. Synthesis of Enantiomerically Pure 5-Substituted Piperazine-2-Acetic Acid Esters as Intermediates for Library Production. J Org Chem. 2019 05 17; 84(10):6040-6064.
    View in: PubMed
    Score: 0.169
  5. Correction to Synthesis of Enantiomerically Pure 6-Substituted-Piperazine-2-Acetic Acid Esters as Intermediates for Library Production. J Org Chem. 2019 Apr 05; 84(7):4575.
    View in: PubMed
    Score: 0.167
  6. Synthesis of Enantiomerically Pure 3-Substituted Piperazine-2-acetic Acid Esters as Intermediates for Library Production. J Org Chem. 2018 10 05; 83(19):11777-11793.
    View in: PubMed
    Score: 0.162
  7. Synthesis of Enantiomerically Pure 6-Substituted-Piperazine-2-Acetic Acid Esters as Intermediates for Library Production. J Org Chem. 2018 06 15; 83(12):6541-6555.
    View in: PubMed
    Score: 0.159
  8. Discovery of highly potent and ALK2/ALK1 selective kinase inhibitors using DNA-encoded chemistry technology. Proc Natl Acad Sci U S A. 2024 Nov 19; 121(47):e2413108121.
    View in: PubMed
    Score: 0.062
  9. CYP3A Mediates an Unusual C(sp2)-C(sp3) Bond Cleavage via Ipso-Addition of Oxygen in Drug Metabolism. Angew Chem Int Ed Engl. 2024 06 03; 63(23):e202405197.
    View in: PubMed
    Score: 0.060
  10. Expanding Complex Morpholines Using Systematic Chemical Diversity. Org Lett. 2024 May 03; 26(17):3493-3497.
    View in: PubMed
    Score: 0.059
  11. SPA-STOCSY: an automated tool for identifying annotated and non-annotated metabolites in high-throughput NMR spectra. Bioinformatics. 2023 10 03; 39(10).
    View in: PubMed
    Score: 0.057
  12. Heterocyclic Merging of Stereochemically Diverse Chiral Piperazines and Morpholines with Indazoles. Chemistry. 2023 Oct 02; 29(55):e202301888.
    View in: PubMed
    Score: 0.057
  13. Identifying the Reactive Metabolites of Tyrosine Kinase Inhibitor Pexidartinib In Vitro Using LC-MS-Based Metabolomic Approaches. Chem Res Toxicol. 2023 08 21; 36(8):1427-1438.
    View in: PubMed
    Score: 0.057
  14. SPA-STOCSY: An Automated Tool for Identification of Annotated and Non-Annotated Metabolites in High-Throughput NMR Spectra. bioRxiv. 2023 Feb 22.
    View in: PubMed
    Score: 0.055
  15. The roles of Cyp1a2 and Cyp2d in pharmacokinetic profiles of serotonin and norepinephrine reuptake inhibitor duloxetine and its metabolites in mice. Eur J Pharm Sci. 2023 Feb 01; 181:106358.
    View in: PubMed
    Score: 0.054
  16. Advancing ASMS with LC-MS/MS for the discovery of novel PDCL2 ligands from DNA-encoded chemical library selections. Andrology. 2023 07; 11(5):808-815.
    View in: PubMed
    Score: 0.054
  17. Oleic acid is an endogenous ligand of TLX/NR2E1 that triggers hippocampal neurogenesis. Proc Natl Acad Sci U S A. 2022 03 29; 119(13):e2023784119.
    View in: PubMed
    Score: 0.052
  18. Metabolism of JQ1, an inhibitor of bromodomain and extra terminal bromodomain proteins, in human and mouse liver microsomes?. Biol Reprod. 2020 08 04; 103(2):427-436.
    View in: PubMed
    Score: 0.046
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.