Chandra Bhushan Mishra to Drug Design
This is a "connection" page, showing publications Chandra Bhushan Mishra has written about Drug Design.
Connection Strength
3.613
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Development of novel carbazole derivatives with effective multifunctional action against Alzheimer's diseases: Design, synthesis, in silico, in vitro and in vivo investigation. Bioorg Chem. 2020 01; 95:103524.
Score: 0.627
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Design, synthesis, in-silico and biological evaluation of novel donepezil derivatives as multi-target-directed ligands for the treatment of Alzheimer's disease. Eur J Med Chem. 2017 Jan 05; 125:736-750.
Score: 0.500
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Design, synthesis and biological evaluation of N-(5-methyl-isoxazol-3-yl/1,3,4-thiadiazol-2-yl)-4-(3-substitutedphenylureido) benzenesulfonamides as human carbonic anhydrase isoenzymes I, II, VII and XII inhibitors. J Enzyme Inhib Med Chem. 2016; 31(sup2):174-179.
Score: 0.491
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Design and synthesis of some new 1-phenyl-3/4-[4-(aryl/heteroaryl/alkyl-piperazine1-yl)-phenyl-ureas as potent anticonvulsant and antidepressant agents. Arch Pharm Res. 2016 May; 39(5):603-17.
Score: 0.480
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Design and synthesis of (4E)-4-(4-substitutedbenzylideneamino)-3-substituted-2,3-dihydro-2-thioxothiazole-5-carbonitrile as novel A2A receptor antagonists. Bioorg Med Chem. 2013 Oct 01; 21(19):6077-83.
Score: 0.401
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Discovery of Potent Carbonic Anhydrase Inhibitors as Effective Anticonvulsant Agents: Drug Design, Synthesis, and In Vitro and In Vivo Investigations. J Med Chem. 2021 03 25; 64(6):3100-3114.
Score: 0.170
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Discovery of potent anti-convulsant carbonic anhydrase inhibitors: Design, synthesis, in?vitro and in?vivo appraisal. Eur J Med Chem. 2018 Aug 05; 156:430-443.
Score: 0.142
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Discovery of novel Methylsulfonyl phenyl derivatives as potent human Cyclooxygenase-2 inhibitors with effective anticonvulsant action: Design, synthesis, in-silico, in-vitro and in-vivo evaluation. Eur J Med Chem. 2018 May 10; 151:520-532.
Score: 0.139
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Discovery of Benzenesulfonamide Derivatives as Carbonic Anhydrase Inhibitors with Effective Anticonvulsant Action: Design, Synthesis, and Pharmacological Evaluation. J Med Chem. 2018 04 12; 61(7):3151-3165.
Score: 0.139
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Discovery of Benzenesulfonamides with Potent Human Carbonic Anhydrase Inhibitory and Effective Anticonvulsant Action: Design, Synthesis, and Pharmacological Assessment. J Med Chem. 2017 03 23; 60(6):2456-2469.
Score: 0.129
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Design, synthesis, in silico and biological evaluation of novel 2-(4-(4-substituted piperazin-1-yl)benzylidene)hydrazine carboxamides. Mol Divers. 2017 Feb; 21(1):163-174.
Score: 0.127
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Design, synthesis and evaluation of novel indandione derivatives as multifunctional agents with cholinesterase inhibition, anti-?-amyloid aggregation, antioxidant and neuroprotection properties against Alzheimer's disease. Bioorg Med Chem. 2016 08 15; 24(16):3829-41.
Score: 0.123
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Design and synthesis of a novel class of carbonic anhydrase-IX inhibitor 1-(3-(phenyl/4-fluorophenyl)-7-imino-3H-[1,2,3]triazolo[4,5d]pyrimidin 6(7H)yl)urea. J Mol Graph Model. 2016 Mar; 64:101-109.
Score: 0.119
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Design, synthesis and pharmacological evaluation of N-[4-(4-(alkyl/aryl/heteroaryl)-piperazin-1-yl)-phenyl]-carbamic acid ethyl ester derivatives as novel anticonvulsant agents. Bioorg Med Chem Lett. 2015 Mar 01; 25(5):1092-9.
Score: 0.028