Recombinant, chimaeric live, attenuated vaccine (ChimeriVax) incorporating the envelope genes of Japanese encephalitis (SA14-14-2) virus and the capsid and nonstructural genes of yellow fever (17D) virus is safe, immunogenic and protective in non-human primates.

Recombinant, chimaeric live, attenuated vaccine (ChimeriVax) incorporating the envelope genes of Japanese encephalitis (SA14-14-2) virus and the capsid and nonstructural genes of yellow fever (17D) virus is safe, immunogenic and protective in non-human primates. Vaccine. 1999 Apr 09; 17(15-16):1869-82.

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subject areas

Animals
Capsid
Cell Line
Central Nervous System
Dose-Response Relationship, Immunologic
Drug Evaluation, Preclinical
Encephalitis Virus, Japanese
Encephalitis, Japanese
Macaca mulatta
Neutralization Tests
Sequence Analysis, DNA
Vaccination
Vaccines, Attenuated
Vaccines, Synthetic
Viral Envelope Proteins
Viral Nonstructural Proteins
Viral Proteins
Viral Vaccines
Viremia
Yellow fever virus

authors with profiles

THOMAS MONATH