Voltage-Gated Sodium Channel Blockers
"Voltage-Gated Sodium Channel Blockers" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A class of drugs that inhibit the activation of VOLTAGE-GATED SODIUM CHANNELS.
| Descriptor ID |
D061567
|
| MeSH Number(s) |
D27.505.519.562.750.500 D27.505.954.411.720.500
|
| Concept/Terms |
Voltage-Gated Sodium Channel Blockers- Voltage-Gated Sodium Channel Blockers
- Voltage Gated Sodium Channel Blockers
- Voltage-Gated Sodium Channel Inhibitors
- Voltage Gated Sodium Channel Inhibitors
- Channel Blockers, Voltage-Gated Sodium
- Channel Blockers, Voltage Gated Sodium
- Voltage-Gated Sodium Channel Antagonists
- Voltage Gated Sodium Channel Antagonists
|
Below are MeSH descriptors whose meaning is more general than "Voltage-Gated Sodium Channel Blockers".
Below are MeSH descriptors whose meaning is more specific than "Voltage-Gated Sodium Channel Blockers".
This graph shows the total number of publications written about "Voltage-Gated Sodium Channel Blockers" by people in this website by year, and whether "Voltage-Gated Sodium Channel Blockers" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2016 | 1 | 0 | 1 |
| 2017 | 2 | 0 | 2 |
| 2020 | 0 | 1 | 1 |
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Below are the most recent publications written about "Voltage-Gated Sodium Channel Blockers" by people in Profiles.
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Lacosamide induced Brugada I morphology in the setting of septicemia: A case report. Medicine (Baltimore). 2021 May 07; 100(18):e25577.
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A pilot study on the acute conversion and maintenance of sinus rhythm in rheumatic atrial fibrillation using oral flecainide. Indian Heart J. 2020 Sep - Oct; 72(5):383-388.
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Discovery of aminocyclohexene analogues as selective and orally bioavailable hNav1.7 inhibitors for analgesia. Bioorg Med Chem Lett. 2017 11 15; 27(22):4979-4984.
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The discovery of tetrahydropyridine analogs as hNav1.7 selective inhibitors for analgesia. Bioorg Med Chem Lett. 2017 05 15; 27(10):2210-2215.
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HYP-17, a novel voltage-gated sodium channel blocker, relieves inflammatory and neuropathic pain in rats. Pharmacol Biochem Behav. 2017 02; 153:116-129.
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Application of a Parallel Synthetic Strategy in the Discovery of Biaryl Acyl Sulfonamides as Efficient and Selective NaV1.7 Inhibitors. J Med Chem. 2016 09 08; 59(17):7818-39.