"Proof of Concept Study" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An empirical investigation which pertains to the development of prototypes or models that demonstrate the feasibility of novel concepts, ideas, principles, schema or their practical application.
| Descriptor ID |
D000075082
|
| MeSH Number(s) |
H01.770.644.578
|
| Concept/Terms |
Proof of Concept Study- Proof of Concept Study
- Concept Study Proof
- Study Proof, Concept
- Proof of Concept Investigation
- Concept Investigation Proof
- Investigation Proof, Concept
- Proof of Concept Research
- Concept Research Proof
- Concept Research Proofs
- Research Proof, Concept
- Proof of Concept Testing
- Concept Testing Proof
- Concept Testing Proofs
- Testing Proof, Concept
- Testing Proofs, Concept
- Proof of Concept Experiment
- Concept Experiment Proof
- Concept Experiment Proofs
- Experiment Proof, Concept
- Proof of Concept Approach
- Approach Proof, Concept
- Approach Proofs, Concept
- Concept Approach Proof
- Concept Approach Proofs
- Proof of Concept Studies
Proof of Concept Prototype- Proof of Concept Prototype
- Concept Prototype Proof
- Concept Prototype Proofs
- Prototype Proof, Concept
- Proof of Concept Model
- Concept Model Proof
- Concept Model Proofs
- Model Proof, Concept
Proof of Concept Evaluation- Proof of Concept Evaluation
- Concept Evaluation Proof
- Concept Evaluation Proofs
- Evaluation Proof, Concept
- Proof of Concept Demonstration
- Concept Demonstration Proof
- Demonstration Proof, Concept
|
Below are MeSH descriptors whose meaning is more general than "Proof of Concept Study".
Below are MeSH descriptors whose meaning is more specific than "Proof of Concept Study".
This graph shows the total number of publications written about "Proof of Concept Study" by people in this website by year, and whether "Proof of Concept Study" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2016 | 0 | 1 | 1 |
| 2017 | 0 | 1 | 1 |
| 2018 | 0 | 5 | 5 |
| 2019 | 0 | 5 | 5 |
| 2020 | 0 | 3 | 3 |
| 2021 | 0 | 3 | 3 |
| 2024 | 1 | 3 | 4 |
| 2025 | 0 | 3 | 3 |
To return to the timeline,
click here.
Below are the most recent publications written about "Proof of Concept Study" by people in Profiles.
-
A Phase 2 Randomized Trial of NBI-1065846 (TAK-041) in Patients With Anhedonia Associated With Major Depressive Disorder: Results of the TERPSIS Study. J Clin Psychopharmacol. 2025 Sep-Oct 01; 45(5):432-440.
-
A Proof-of-Concept Study Investigating the Effects of Transcranial Plus Intranasal Photobiomodulation on Cognitive Function after Repetitive Head Acceleration Events. Photobiomodul Photomed Laser Surg. 2025 Sep; 43(9):400-410.
-
CRISPR-Cas9 mediated proteinase 3 autoantigen deletion as a treatment strategy for anti-neutrophil cytoplasmic autoantibody-associated vasculitis. Kidney Int. 2025 Jul; 108(1):145-149.
-
Individualized functional magnetic resonance imaging neuromodulation enhances visuospatial perception: a proof-of-concept study. Philos Trans R Soc Lond B Biol Sci. 2024 Dec 02; 379(1915):20230083.
-
The Effect of Intranasal Plus Transcranial Photobiomodulation on Neuromuscular Control in Individuals with Repetitive Head Acceleration Events. Photobiomodul Photomed Laser Surg. 2024 Jun; 42(6):404-413.
-
Evolving growth hormone deficiency: proof of concept. Front Endocrinol (Lausanne). 2024; 15:1398171.
-
Weight Loss for Patients With Gout and Concomitant Obesity: A Proof-of-Concept Randomized Trial. Arthritis Rheumatol. 2024 May; 76(5):806-812.
-
The expression of pregnancy-associated plasma protein-A (PAPP-A) in human blastocoel fluid-conditioned media: a proof of concept study. J Assist Reprod Genet. 2022 Feb; 39(2):389-394.
-
A phase 1 trial of lipid-encapsulated mRNA encoding a monoclonal antibody with neutralizing activity against Chikungunya virus. Nat Med. 2021 12; 27(12):2224-2233.
-
Development of a Health Disparities Index: Proof of Concept with Chest Radiography in Asthma. J Pediatr. 2021 11; 238:290-295.e1.