"Proof of Concept Study" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An empirical investigation which pertains to the development of prototypes or models that demonstrate the feasibility of novel concepts, ideas, principles, schema or their practical application.
| Descriptor ID |
D000075082
|
| MeSH Number(s) |
H01.770.644.578
|
| Concept/Terms |
Proof of Concept Study- Proof of Concept Study
- Concept Study Proof
- Study Proof, Concept
- Proof of Concept Investigation
- Concept Investigation Proof
- Investigation Proof, Concept
- Proof of Concept Research
- Concept Research Proof
- Concept Research Proofs
- Research Proof, Concept
- Proof of Concept Testing
- Concept Testing Proof
- Concept Testing Proofs
- Testing Proof, Concept
- Testing Proofs, Concept
- Proof of Concept Experiment
- Concept Experiment Proof
- Concept Experiment Proofs
- Experiment Proof, Concept
- Proof of Concept Approach
- Approach Proof, Concept
- Approach Proofs, Concept
- Concept Approach Proof
- Concept Approach Proofs
- Proof of Concept Studies
Proof of Concept Prototype- Proof of Concept Prototype
- Concept Prototype Proof
- Concept Prototype Proofs
- Prototype Proof, Concept
- Proof of Concept Model
- Concept Model Proof
- Concept Model Proofs
- Model Proof, Concept
Proof of Concept Evaluation- Proof of Concept Evaluation
- Concept Evaluation Proof
- Concept Evaluation Proofs
- Evaluation Proof, Concept
- Proof of Concept Demonstration
- Concept Demonstration Proof
- Demonstration Proof, Concept
|
Below are MeSH descriptors whose meaning is more general than "Proof of Concept Study".
Below are MeSH descriptors whose meaning is more specific than "Proof of Concept Study".
This graph shows the total number of publications written about "Proof of Concept Study" by people in this website by year, and whether "Proof of Concept Study" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2016 | 0 | 1 | 1 |
| 2017 | 0 | 1 | 1 |
| 2018 | 0 | 5 | 5 |
| 2019 | 1 | 5 | 6 |
| 2020 | 0 | 3 | 3 |
| 2021 | 0 | 4 | 4 |
| 2024 | 1 | 3 | 4 |
| 2025 | 1 | 5 | 6 |
| 2026 | 0 | 1 | 1 |
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Below are the most recent publications written about "Proof of Concept Study" by people in Profiles.
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Remote alcohol biomarker monitoring to promote drinking reductions among people with HIV: A proof-of-concept pilot study. J Subst Use Addict Treat. 2026 Aug; 187:209957.
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A proof-of-concept study of pitolisant for excessive daytime sleepiness in patients with Prader-Willi syndrome. J Clin Sleep Med. 2025 11 01; 21(11):1893-1902.
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Impact of Anthelmintic Therapy for Invasive Helminth Infection on Microbial Translocation, Inflammation, and Immune Response among Ugandans Living with HIV: A Randomized Proof of Concept Study. Am J Trop Med Hyg. 2025 Dec 03; 113(6):1300-1310.
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A Proof-of-Concept Study Investigating the Effects of Transcranial Plus Intranasal Photobiomodulation on Cognitive Function after Repetitive Head Acceleration Events. Photobiomodul Photomed Laser Surg. 2025 Sep; 43(9):400-410.
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A Technical Assessment of a Commercial GFAP Lateral Flow Assay to Establish Proof-of-Concept for Use in Traumatic Brain Injury. Cell Mol Neurobiol. 2025 Jul 12; 45(1):69.
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A Computed Tomography-Based Score to Predict Survival in Patients With Adrenocortical Carcinoma: A Proof-of-Concept Study. Can Assoc Radiol J. 2025 Nov; 76(4):683-691.
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CRISPR-Cas9 mediated proteinase 3 autoantigen deletion as a treatment strategy for anti-neutrophil cytoplasmic autoantibody-associated vasculitis. Kidney Int. 2025 Jul; 108(1):145-149.
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Individualized functional magnetic resonance imaging neuromodulation enhances visuospatial perception: a proof-of-concept study. Philos Trans R Soc Lond B Biol Sci. 2024 12 02; 379(1915):20230083.
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The Effect of Intranasal Plus Transcranial Photobiomodulation on Neuromuscular Control in Individuals with Repetitive Head Acceleration Events. Photobiomodul Photomed Laser Surg. 2024 Jun; 42(6):404-413.
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Evolving growth hormone deficiency: proof of concept. Front Endocrinol (Lausanne). 2024; 15:1398171.