"MutS Homolog 3 Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A MutS homolog protein and component of post-replicative DNA MISMATCH REPAIR. It forms a heterodimer with MUTS HOMOLOG 2 PROTEIN (MSH2) and recognizes large insertion-deletion loops up to 13 nucleotides in length. This directs downstream events such as strand discrimination, excision, and resynthesis.
| Descriptor ID |
D000074081
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| MeSH Number(s) |
D12.776.260.556.875
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "MutS Homolog 3 Protein".
Below are MeSH descriptors whose meaning is more specific than "MutS Homolog 3 Protein".
This graph shows the total number of publications written about "MutS Homolog 3 Protein" by people in this website by year, and whether "MutS Homolog 3 Protein" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 |
| 1999 | 0 | 1 | 1 |
| 2000 | 0 | 4 | 4 |
| 2002 | 0 | 2 | 2 |
| 2004 | 0 | 1 | 1 |
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Below are the most recent publications written about "MutS Homolog 3 Protein" by people in Profiles.
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The role of hMSH3 and hMSH6 in ovarian endometrioid carcinoma and relationship with microsatellite instability phenotype. Oncol Rep. 2004 Dec; 12(6):1217-9.
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Cellular and molecular biology of biliary tract cancers. Surg Oncol Clin N Am. 2002 Oct; 11(4):995-1009.
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Expression of heavy subunit of gamma-glutamylcysteine synthetase (gamma-GCSh) in human colorectal carcinoma. Int J Cancer. 2002 Jan 01; 97(1):21-7.
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Multidrug resistance protein functionality: no effect of intracellular or extracellular pH changes. Biochem Pharmacol. 2000 Nov 15; 60(10):1485-9.
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Multidrug resistance transporters and modulation. Curr Opin Oncol. 2000 Sep; 12(5):450-8.
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Genetic progression in microsatellite instability high (MSI-H) colon cancers correlates with clinico-pathological parameters: A study of the TGRbetaRII, BAX, hMSH3, hMSH6, IGFIIR and BLM genes. Int J Cancer. 2000 May 20; 89(3):230-5.
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The effect of glutathione on the ATPase activity of MRP1 in its natural membranes. FEBS Lett. 2000 Mar 03; 469(1):47-51.
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Correlation between the kinetics of anthracycline uptake and the resistance factor in cancer cells expressing the multidrug resistance protein or the P-glycoprotein. Biochim Biophys Acta. 1999 Jul 08; 1450(3):374-84.
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Mutation of hMSH3 and hMSH6 mismatch repair genes in genetically unstable human colorectal and gastric carcinomas. Hum Mutat. 1997; 10(6):474-8.