"Pyroptosis" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Type of programmed cell death associated with infection by intracellular pathogens. It is characterized by INFLAMMASOME formation; activation of CASPASE 1; and CYTOKINES mediated inflammation.
Descriptor ID |
D000069292
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MeSH Number(s) |
G04.146.160.530
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Concept/Terms |
Pyroptosis- Pyroptosis
- Pyroptoses
- Pyroptotic Cell Death
- Cell Death, Pyroptotic
- Cell Deaths, Pyroptotic
- Death, Pyroptotic Cell
- Deaths, Pyroptotic Cell
- Pyroptotic Cell Deaths
- Inflammatory Apoptosis
- Apoptoses, Inflammatory
- Apoptosis, Inflammatory
- Inflammatory Apoptoses
- Caspase-1 Dependent Cell Death
- Caspase 1 Dependent Cell Death
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Below are MeSH descriptors whose meaning is more general than "Pyroptosis".
Below are MeSH descriptors whose meaning is more specific than "Pyroptosis".
This graph shows the total number of publications written about "Pyroptosis" by people in this website by year, and whether "Pyroptosis" was a major or minor topic of these publications.
To see the data from this visualization as text,
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Year | Major Topic | Minor Topic | Total |
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2016 | 1 | 0 | 1 |
2018 | 1 | 0 | 1 |
2019 | 0 | 1 | 1 |
2020 | 1 | 0 | 1 |
2021 | 1 | 2 | 3 |
2022 | 1 | 1 | 2 |
2023 | 2 | 1 | 3 |
2024 | 0 | 2 | 2 |
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Below are the most recent publications written about "Pyroptosis" by people in Profiles.
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LncRNA Malat1 suppresses pyroptosis and T cell-mediated killing of incipient metastatic cells. Nat Cancer. 2024 Feb; 5(2):262-282.
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Gasdermin C sensitizes tumor cells to PARP inhibitor therapy in cancer models. J Clin Invest. 2024 Jan 02; 134(1).
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Gasdermins and cancers. Semin Immunol. 2023 11; 70:101833.
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Alternative splicing of GSDMB modulates killer lymphocyte-triggered pyroptosis. Sci Immunol. 2023 04 28; 8(82):eadg3196.
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Detection of Gasdermin C-Mediated Cancer Cell Pyroptosis. Methods Mol Biol. 2023; 2641:135-146.
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Visualization of Inflammatory Caspases Induced Proximity in Human Monocyte-Derived Macrophages. J Vis Exp. 2022 04 06; (182).
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GSDMB is increased in IBD and regulates epithelial restitution/repair independent of pyroptosis. Cell. 2022 01 20; 185(2):283-298.e17.
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The molecular mosaic of regulated cell death in the cardiovascular system. Biochim Biophys Acta Mol Basis Dis. 2022 01 01; 1868(1):166297.
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Genetic targeting of Card19 is linked to disrupted NINJ1 expression, impaired cell lysis, and increased susceptibility to Yersinia infection. PLoS Pathog. 2021 10; 17(10):e1009967.
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Molecular mechanisms and functions of pyroptosis in inflammation and antitumor immunity. Mol Cell. 2021 11 18; 81(22):4579-4590.