"Pyroptosis" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Type of programmed cell death associated with infection by intracellular pathogens. It is characterized by INFLAMMASOME formation; activation of CASPASE 1; and CYTOKINES mediated inflammation.
Descriptor ID |
D000069292
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MeSH Number(s) |
G04.146.160.530
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Concept/Terms |
Pyroptosis- Pyroptosis
- Pyroptoses
- Pyroptotic Cell Death
- Cell Death, Pyroptotic
- Cell Deaths, Pyroptotic
- Death, Pyroptotic Cell
- Deaths, Pyroptotic Cell
- Pyroptotic Cell Deaths
- Inflammatory Apoptosis
- Apoptoses, Inflammatory
- Apoptosis, Inflammatory
- Inflammatory Apoptoses
- Caspase-1 Dependent Cell Death
- Caspase 1 Dependent Cell Death
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Below are MeSH descriptors whose meaning is more general than "Pyroptosis".
Below are MeSH descriptors whose meaning is more specific than "Pyroptosis".
This graph shows the total number of publications written about "Pyroptosis" by people in this website by year, and whether "Pyroptosis" was a major or minor topic of these publications.
To see the data from this visualization as text,
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Year | Major Topic | Minor Topic | Total |
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2016 | 1 | 0 | 1 |
2018 | 1 | 1 | 2 |
2019 | 0 | 1 | 1 |
2020 | 1 | 1 | 2 |
2021 | 1 | 2 | 3 |
2022 | 1 | 1 | 2 |
2023 | 2 | 1 | 3 |
2024 | 4 | 3 | 7 |
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Below are the most recent publications written about "Pyroptosis" by people in Profiles.
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IRE1a silences dsRNA to prevent taxane-induced pyroptosis in triple-negative breast cancer. Cell. 2024 Dec 12; 187(25):7248-7266.e34.
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Determining the Feasibility of a Cadmium Exposure Model to Activate the Inflammatory Arm of PANoptosis in Murine Monocytes. Int J Mol Sci. 2024 Sep 26; 25(19).
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Potentially functional variants of CHMP4A and PANX1 in the pyroptosis-related pathway predict survival of patients with non-oropharyngeal head and neck squamous cell carcinoma. Mol Carcinog. 2024 Sep; 63(9):1712-1721.
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Role of hypoxia-mediated pyroptosis?in the development of extending knee joint contracture in rats. Eur J Med Res. 2024 May 27; 29(1):298.
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Mitochondrial (mt)DNA-cyclic GMP-AMP synthase (cGAS)-stimulator of interferon genes (STING) signaling promotes pyroptosis of macrophages via interferon regulatory factor (IRF)7/IRF3 activation to aggravate lung injury during severe acute pancreatitis. Cell Mol Biol Lett. 2024 Apr 27; 29(1):61.
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LncRNA Malat1 suppresses pyroptosis and T cell-mediated killing of incipient metastatic cells. Nat Cancer. 2024 Feb; 5(2):262-282.
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Gasdermin C sensitizes tumor cells to PARP inhibitor therapy in cancer models. J Clin Invest. 2024 Jan 02; 134(1).
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Gasdermins and cancers. Semin Immunol. 2023 11; 70:101833.
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Alternative splicing of GSDMB modulates killer lymphocyte-triggered pyroptosis. Sci Immunol. 2023 04 28; 8(82):eadg3196.
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Detection of Gasdermin C-Mediated Cancer Cell Pyroptosis. Methods Mol Biol. 2023; 2641:135-146.