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XANDER WEHRENS to Mice, Transgenic

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This is a "connection" page, showing publications XANDER WEHRENS has written about Mice, Transgenic.
XANDER WEHRENS
Connection Strength
2.346
Mice, Transgenic
  1. Pathways to precision medicine: deciphering the secrets of physiological and pathological atrial enlargement. Clin Sci (Lond). 2024 Sep 18; 138(18):1173-1177.
    View in: PubMed
    Score: 0.635
  2. Ca2+/calmodulin-dependent kinase IIdC-induced chronic heart failure does not depend on sarcoplasmic reticulum Ca2+ leak. ESC Heart Fail. 2024 Aug; 11(4):2191-2199.
    View in: PubMed
    Score: 0.154
  3. Atrial proteomic profiling reveals a switch towards profibrotic gene expression program in CREM-Ib?C-X mice with persistent atrial fibrillation. J Mol Cell Cardiol. 2024 May; 190:1-12.
    View in: PubMed
    Score: 0.153
  4. Determinants of Ca2+ release restitution: Insights from genetically altered animals and mathematical modeling. J Gen Physiol. 2020 11 02; 152(11).
    View in: PubMed
    Score: 0.121
  5. Atrial-Specific Gene Delivery Using an Adeno-Associated Viral Vector. Circ Res. 2019 01 18; 124(2):256-262.
    View in: PubMed
    Score: 0.107
  6. In Vivo Ryr2 Editing Corrects Catecholaminergic Polymorphic Ventricular Tachycardia. Circ Res. 2018 Sep 28; 123(8):953-963.
    View in: PubMed
    Score: 0.105
  7. Oxidized CaMKII (Ca2+/Calmodulin-Dependent Protein Kinase II) Is Essential for Ventricular Arrhythmia in a Mouse Model of Duchenne Muscular Dystrophy. Circ Arrhythm Electrophysiol. 2018 04; 11(4):e005682.
    View in: PubMed
    Score: 0.101
  8. Early effects of Epac depend on the fine-tuning of the sarcoplasmic reticulum Ca2+ handling in cardiomyocytes. J Mol Cell Cardiol. 2018 01; 114:1-9.
    View in: PubMed
    Score: 0.098
  9. Treatment of catecholaminergic polymorphic ventricular tachycardia in mice using novel RyR2-modifying drugs. Int J Cardiol. 2017 Jan 15; 227:668-673.
    View in: PubMed
    Score: 0.092
  10. Disrupted junctional membrane complexes and hyperactive ryanodine receptors after acute junctophilin knockdown in mice. Circulation. 2011 Mar 08; 123(9):979-88.
    View in: PubMed
    Score: 0.062
  11. Ryanodine receptor phosphorylation by calcium/calmodulin-dependent protein kinase II promotes life-threatening ventricular arrhythmias in mice with heart failure. Circulation. 2010 Dec 21; 122(25):2669-79.
    View in: PubMed
    Score: 0.061
  12. Transthoracic echocardiography in mice. J Vis Exp. 2010 May 28; (39).
    View in: PubMed
    Score: 0.059
  13. Genetic inhibition of nuclear factor of activated T-cell c2 prevents atrial fibrillation in CREM transgenic mice. Cardiovasc Res. 2022 10 21; 118(13):2805-2818.
    View in: PubMed
    Score: 0.035
  14. Reversible cardiac disease features in an inducible CUG repeat RNA-expressing mouse model of myotonic dystrophy. JCI Insight. 2021 03 08; 6(5).
    View in: PubMed
    Score: 0.031
  15. Exercise restores dysregulated gene expression in a mouse model of arrhythmogenic cardiomyopathy. Cardiovasc Res. 2020 05 01; 116(6):1199-1213.
    View in: PubMed
    Score: 0.029
  16. Prevention of connexin-43 remodeling protects against Duchenne muscular dystrophy cardiomyopathy. J Clin Invest. 2020 04 01; 130(4):1713-1727.
    View in: PubMed
    Score: 0.029
  17. Depletion of Endothelial Prolyl Hydroxylase Domain Protein 2 and 3 Promotes Cardiomyocyte Proliferation and Prevents Ventricular Failure Induced by Myocardial Infarction. Circulation. 2019 07 30; 140(5):440-442.
    View in: PubMed
    Score: 0.028
  18. YAP Partially Reprograms Chromatin Accessibility to Directly Induce Adult Cardiogenesis In?Vivo. Dev Cell. 2019 03 25; 48(6):765-779.e7.
    View in: PubMed
    Score: 0.027
  19. CRISPR -Mediated Expression of the Fetal Scn5a Isoform in Adult Mice Causes Conduction Defects and Arrhythmias. J Am Heart Assoc. 2018 10 02; 7(19):e010393.
    View in: PubMed
    Score: 0.026
  20. Reversible redox modifications of ryanodine receptor ameliorate ventricular arrhythmias in the ischemic-reperfused heart. Am J Physiol Heart Circ Physiol. 2016 09 01; 311(3):H713-24.
    View in: PubMed
    Score: 0.023
  21. Phospholamban ablation rescues the enhanced propensity to arrhythmias of mice with CaMKII-constitutive phosphorylation of RyR2 at site S2814. J Physiol. 2016 06 01; 594(11):3005-30.
    View in: PubMed
    Score: 0.022
  22. A Single Protein Kinase A or Calmodulin Kinase II Site Does Not Control the Cardiac Pacemaker Ca2+ Clock. Circ Arrhythm Electrophysiol. 2016 Feb; 9(2):e003180.
    View in: PubMed
    Score: 0.022
  23. Cardiac expression of the CREM repressor isoform CREM-Ib?C-X in mice leads to arrhythmogenic alterations in ventricular cardiomyocytes. Basic Res Cardiol. 2016 Mar; 111(2):15.
    View in: PubMed
    Score: 0.022
  24. PHD2/3-dependent hydroxylation tunes cardiac response to ?-adrenergic stress via phospholamban. J Clin Invest. 2015 Jul 01; 125(7):2759-71.
    View in: PubMed
    Score: 0.021
  25. The mitochondrial uniporter controls fight or flight heart rate increases. Nat Commun. 2015 Jan 20; 6:6081.
    View in: PubMed
    Score: 0.020
  26. CaMKII-dependent phosphorylation of cardiac ryanodine receptors regulates cell death in cardiac ischemia/reperfusion injury. J Mol Cell Cardiol. 2014 Sep; 74:274-83.
    View in: PubMed
    Score: 0.019
  27. Ryanodine receptor-mediated calcium leak drives progressive development of an atrial fibrillation substrate in a transgenic mouse model. Circulation. 2014 Mar 25; 129(12):1276-1285.
    View in: PubMed
    Score: 0.019
  28. microRNA-22 promotes heart failure through coordinate suppression of PPAR/ERR-nuclear hormone receptor transcription. PLoS One. 2013; 8(9):e75882.
    View in: PubMed
    Score: 0.019
  29. CaMKII effects on inotropic but not lusitropic force frequency responses require phospholamban. J Mol Cell Cardiol. 2012 Sep; 53(3):429-36.
    View in: PubMed
    Score: 0.017
  30. Human stanniocalcin-1 suppresses angiotensin II-induced superoxide generation in cardiomyocytes through UCP3-mediated anti-oxidant pathway. PLoS One. 2012; 7(5):e36994.
    View in: PubMed
    Score: 0.017
  31. Role of RyR2 phosphorylation at S2814 during heart failure progression. Circ Res. 2012 May 25; 110(11):1474-83.
    View in: PubMed
    Score: 0.017
  32. Overexpression of cAMP-response element modulator causes abnormal growth and development of the atrial myocardium resulting in a substrate for sustained atrial fibrillation in mice. Int J Cardiol. 2013 Jun 20; 166(2):366-74.
    View in: PubMed
    Score: 0.016
  33. Calcium-calmodulin dependent protein kinase II (CaMKII): a main signal responsible for early reperfusion arrhythmias. J Mol Cell Cardiol. 2011 Dec; 51(6):936-44.
    View in: PubMed
    Score: 0.016
  34. Heart-specific overexpression of CUGBP1 reproduces functional and molecular abnormalities of myotonic dystrophy type 1. Hum Mol Genet. 2010 Mar 15; 19(6):1066-75.
    View in: PubMed
    Score: 0.014
  35. Sudden infant death syndrome in mice with an inherited mutation in RyR2. Circ Arrhythm Electrophysiol. 2009 Dec; 2(6):677-85.
    View in: PubMed
    Score: 0.014
  36. PKC inhibition ameliorates the cardiac phenotype in a mouse model of myotonic dystrophy type 1. J Clin Invest. 2009 Dec; 119(12):3797-806.
    View in: PubMed
    Score: 0.014
  37. Calmodulin kinase II-mediated sarcoplasmic reticulum Ca2+ leak promotes atrial fibrillation in mice. J Clin Invest. 2009 Jul; 119(7):1940-51.
    View in: PubMed
    Score: 0.014
  38. 20p12.3 microdeletion predisposes to Wolff-Parkinson-White syndrome with variable neurocognitive deficits. J Med Genet. 2009 Mar; 46(3):168-75.
    View in: PubMed
    Score: 0.013
  39. NFATc2 is a necessary mediator of calcineurin-dependent cardiac hypertrophy and heart failure. J Biol Chem. 2008 Aug 08; 283(32):22295-303.
    View in: PubMed
    Score: 0.013
  40. Mice with the R176Q cardiac ryanodine receptor mutation exhibit catecholamine-induced ventricular tachycardia and cardiomyopathy. Proc Natl Acad Sci U S A. 2006 Aug 08; 103(32):12179-84.
    View in: PubMed
    Score: 0.011
  41. Analysis of calstabin2 (FKBP12.6)-ryanodine receptor interactions: rescue of heart failure by calstabin2 in mice. Proc Natl Acad Sci U S A. 2006 Feb 28; 103(9):3456-61.
    View in: PubMed
    Score: 0.011
  42. Phosphodiesterase 4D deficiency in the ryanodine-receptor complex promotes heart failure and arrhythmias. Cell. 2005 Oct 07; 123(1):25-35.
    View in: PubMed
    Score: 0.011
  43. Angiogenesis-independent cardioprotection in FGF-1 transgenic mice. Cardiovasc Res. 2002 Sep; 55(4):768-77.
    View in: PubMed
    Score: 0.009
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.