XANDER WEHRENS to Tachycardia, Ventricular
This is a "connection" page, showing publications XANDER WEHRENS has written about Tachycardia, Ventricular.
Connection Strength
6.119
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Genetics, manifestations, and management of catecholaminergic polymorphic ventricular tachycardia. Curr Opin Cardiol. 2025 May 01; 40(3):150-157.
Score: 0.781
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Structure-activity optimization of ryanodine receptor modulators for the treatment of catecholaminergic polymorphic ventricular tachycardia. Heart Rhythm. 2025 Jul; 22(7):e192-e204.
Score: 0.765
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Genome Editing and Cardiac Arrhythmias. Cells. 2023 05 11; 12(10).
Score: 0.694
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Role of Ca2+ in healthy and pathologic cardiac function: from normal excitation-contraction coupling to mutations that cause inherited arrhythmia. Arch Toxicol. 2023 01; 97(1):73-92.
Score: 0.667
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In Vivo Ryr2 Editing Corrects Catecholaminergic Polymorphic Ventricular Tachycardia. Circ Res. 2018 Sep 28; 123(8):953-963.
Score: 0.504
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Treatment of catecholaminergic polymorphic ventricular tachycardia in mice using novel RyR2-modifying drugs. Int J Cardiol. 2017 Jan 15; 227:668-673.
Score: 0.441
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Inhibition of CaMKII phosphorylation of RyR2 prevents inducible ventricular arrhythmias in mice with Duchenne muscular dystrophy. Heart Rhythm. 2013 Apr; 10(4):592-9.
Score: 0.337
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Ryanodine receptor phosphorylation by calcium/calmodulin-dependent protein kinase II promotes life-threatening ventricular arrhythmias in mice with heart failure. Circulation. 2010 Dec 21; 122(25):2669-79.
Score: 0.292
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Leaky ryanodine receptors cause delayed afterdepolarizations and ventricular arrhythmias. Eur Heart J. 2007 May; 28(9):1054-6.
Score: 0.228
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The molecular basis of catecholaminergic polymorphic ventricular tachycardia: what are the different hypotheses regarding mechanisms? Heart Rhythm. 2007 Jun; 4(6):794-7.
Score: 0.223
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Sudden unexplained death caused by cardiac ryanodine receptor (RyR2) mutations. Mayo Clin Proc. 2004 Nov; 79(11):1367-71.
Score: 0.192
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Protection from cardiac arrhythmia through ryanodine receptor-stabilizing protein calstabin2. Science. 2004 Apr 09; 304(5668):292-6.
Score: 0.185
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Targeting pathological leak of ryanodine receptors: preclinical progress and the potential impact on treatments for cardiac arrhythmias and heart failure. Expert Opin Ther Targets. 2020 01; 24(1):25-36.
Score: 0.138
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EL20, a potent antiarrhythmic compound, selectively inhibits calmodulin-deficient ryanodine receptor type 2. Heart Rhythm. 2018 04; 15(4):578-586.
Score: 0.119
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Circadian Variation of Ventricular Arrhythmias in Catecholaminergic Polymorphic Ventricular Tachycardia. JACC Clin Electrophysiol. 2017 11; 3(11):1308-1317.
Score: 0.117
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In silico prediction of drug therapy in catecholaminergic polymorphic ventricular tachycardia. J Physiol. 2016 Feb 01; 594(3):567-93.
Score: 0.104
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Atrial arrhythmogenesis in catecholaminergic polymorphic ventricular tachycardia--is there a mechanistic link between sarcoplasmic reticulum Ca(2+) leak and re-entry? Acta Physiol (Oxf). 2013 Feb; 207(2):208-11.
Score: 0.085
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Sudden infant death syndrome in mice with an inherited mutation in RyR2. Circ Arrhythm Electrophysiol. 2009 Dec; 2(6):677-85.
Score: 0.068
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Mice with the R176Q cardiac ryanodine receptor mutation exhibit catecholamine-induced ventricular tachycardia and cardiomyopathy. Proc Natl Acad Sci U S A. 2006 Aug 08; 103(32):12179-84.
Score: 0.054
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Ryanodine receptor-targeted anti-arrhythmic therapy. Ann N Y Acad Sci. 2005 Jun; 1047:366-75.
Score: 0.050
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Sudden death in familial polymorphic ventricular tachycardia associated with calcium release channel (ryanodine receptor) leak. Circulation. 2004 Jun 29; 109(25):3208-14.
Score: 0.047
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CaMKII-dependent phosphorylation of RyR2 promotes targetable pathological RyR2 conformational shift. J Mol Cell Cardiol. 2016 09; 98:62-72.
Score: 0.027