Connection

XANDER WEHRENS to Myocardium

This is a "connection" page, showing publications XANDER WEHRENS has written about Myocardium.
Connection Strength

3.763
  1. Junctophilin-2 expression rescues atrial dysfunction through polyadic junctional membrane complex biogenesis. JCI Insight. 2019 06 20; 4(12).
    View in: PubMed
    Score: 0.433
  2. Regulating the regulator: Insights into the cardiac protein phosphatase 1 interactome. J Mol Cell Cardiol. 2016 Dec; 101:165-172.
    View in: PubMed
    Score: 0.358
  3. Emerging role of junctophilin-2 as a regulator of calcium handling in the heart. Acta Pharmacol Sin. 2010 Sep; 31(9):1019-21.
    View in: PubMed
    Score: 0.234
  4. Alternative splicing: a key mechanism for ankyrin-B functional diversity? J Mol Cell Cardiol. 2008 Dec; 45(6):709-11.
    View in: PubMed
    Score: 0.206
  5. Phosphorylation of RyR2 and shortening of RyR2 cluster spacing in spontaneously hypertensive rat with heart failure. Am J Physiol Heart Circ Physiol. 2007 Oct; 293(4):H2409-17.
    View in: PubMed
    Score: 0.189
  6. Enhancing calstabin binding to ryanodine receptors improves cardiac and skeletal muscle function in heart failure. Proc Natl Acad Sci U S A. 2005 Jul 05; 102(27):9607-12.
    View in: PubMed
    Score: 0.164
  7. Novel therapeutic approaches for heart failure by normalizing calcium cycling. Nat Rev Drug Discov. 2004 Jul; 3(7):565-73.
    View in: PubMed
    Score: 0.153
  8. Ca2+/calmodulin-dependent protein kinase II phosphorylation regulates the cardiac ryanodine receptor. Circ Res. 2004 Apr 02; 94(6):e61-70.
    View in: PubMed
    Score: 0.150
  9. Altered myocardial lipid regulation in junctophilin-2-associated familial cardiomyopathies. Life Sci Alliance. 2024 May; 7(5).
    View in: PubMed
    Score: 0.150
  10. FKBP12.6 deficiency and defective calcium release channel (ryanodine receptor) function linked to exercise-induced sudden cardiac death. Cell. 2003 Jun 27; 113(7):829-40.
    View in: PubMed
    Score: 0.143
  11. Paracrine signalling by cardiac calcitonin controls atrial fibrogenesis and arrhythmia. Nature. 2020 11; 587(7834):460-465.
    View in: PubMed
    Score: 0.119
  12. Loss of SPEG Inhibitory Phosphorylation of Ryanodine Receptor Type-2 Promotes Atrial Fibrillation. Circulation. 2020 09 22; 142(12):1159-1172.
    View in: PubMed
    Score: 0.117
  13. Prevention of connexin-43 remodeling protects against Duchenne muscular dystrophy cardiomyopathy. J Clin Invest. 2020 04 01; 130(4):1713-1727.
    View in: PubMed
    Score: 0.114
  14. Mouse Models of Cardiac Arrhythmias. Circ Res. 2018 07 20; 123(3):332-334.
    View in: PubMed
    Score: 0.102
  15. Protein phosphatase 2A regulatory subunit B56a limits phosphatase activity in the heart. Sci Signal. 2015 Jul 21; 8(386):ra72.
    View in: PubMed
    Score: 0.083
  16. PHD2/3-dependent hydroxylation tunes cardiac response to ?-adrenergic stress via phospholamban. J Clin Invest. 2015 Jul 01; 125(7):2759-71.
    View in: PubMed
    Score: 0.082
  17. Loss of microRNA-106b-25 cluster promotes atrial fibrillation by enhancing ryanodine receptor type-2 expression and calcium release. Circ Arrhythm Electrophysiol. 2014 Dec; 7(6):1214-22.
    View in: PubMed
    Score: 0.079
  18. Impaired local regulation of ryanodine receptor type 2 by protein phosphatase 1 promotes atrial fibrillation. Cardiovasc Res. 2014 Jul 01; 103(1):178-87.
    View in: PubMed
    Score: 0.076
  19. The junctophilin family of proteins: from bench to bedside. Trends Mol Med. 2014 Jun; 20(6):353-62.
    View in: PubMed
    Score: 0.075
  20. Role of RyR2 phosphorylation at S2814 during heart failure progression. Circ Res. 2012 May 25; 110(11):1474-83.
    View in: PubMed
    Score: 0.066
  21. Overexpression of cAMP-response element modulator causes abnormal growth and development of the atrial myocardium resulting in a substrate for sustained atrial fibrillation in mice. Int J Cardiol. 2013 Jun 20; 166(2):366-74.
    View in: PubMed
    Score: 0.064
  22. Genetic inhibition of PKA phosphorylation of RyR2 prevents dystrophic cardiomyopathy. Proc Natl Acad Sci U S A. 2010 Jul 20; 107(29):13165-70.
    View in: PubMed
    Score: 0.058
  23. Accelerated development of pressure overload-induced cardiac hypertrophy and dysfunction in an RyR2-R176Q knockin mouse model. Hypertension. 2010 Apr; 55(4):932-8.
    View in: PubMed
    Score: 0.057
  24. Heart-specific overexpression of CUGBP1 reproduces functional and molecular abnormalities of myotonic dystrophy type 1. Hum Mol Genet. 2010 Mar 15; 19(6):1066-75.
    View in: PubMed
    Score: 0.056
  25. Sudden infant death syndrome in mice with an inherited mutation in RyR2. Circ Arrhythm Electrophysiol. 2009 Dec; 2(6):677-85.
    View in: PubMed
    Score: 0.056
  26. Exercise training during diabetes attenuates cardiac ryanodine receptor dysregulation. J Appl Physiol (1985). 2009 Apr; 106(4):1280-92.
    View in: PubMed
    Score: 0.052
  27. Mice with the R176Q cardiac ryanodine receptor mutation exhibit catecholamine-induced ventricular tachycardia and cardiomyopathy. Proc Natl Acad Sci U S A. 2006 Aug 08; 103(32):12179-84.
    View in: PubMed
    Score: 0.044
  28. Stabilization of cardiac ryanodine receptor prevents intracellular calcium leak and arrhythmias. Proc Natl Acad Sci U S A. 2006 May 16; 103(20):7906-10.
    View in: PubMed
    Score: 0.044
  29. Phosphodiesterase 4D deficiency in the ryanodine-receptor complex promotes heart failure and arrhythmias. Cell. 2005 Oct 07; 123(1):25-35.
    View in: PubMed
    Score: 0.042
  30. Defective cardiac ryanodine receptor regulation during atrial fibrillation. Circulation. 2005 Apr 26; 111(16):2025-32.
    View in: PubMed
    Score: 0.041
  31. Angiogenesis-independent cardioprotection in FGF-1 transgenic mice. Cardiovasc Res. 2002 Sep; 55(4):768-77.
    View in: PubMed
    Score: 0.034
  32. Tead1 is required for maintaining adult cardiomyocyte function, and its loss results in lethal dilated cardiomyopathy. JCI Insight. 2017 09 07; 2(17).
    View in: PubMed
    Score: 0.024
  33. Dysregulation of RBFOX2 Is an Early Event in Cardiac Pathogenesis of Diabetes. Cell Rep. 2016 06 07; 15(10):2200-2213.
    View in: PubMed
    Score: 0.022
  34. Atrial identity is determined by a COUP-TFII regulatory network. Dev Cell. 2013 May 28; 25(4):417-26.
    View in: PubMed
    Score: 0.018
  35. CaMKII effects on inotropic but not lusitropic force frequency responses require phospholamban. J Mol Cell Cardiol. 2012 Sep; 53(3):429-36.
    View in: PubMed
    Score: 0.017
  36. Targeted deletion of microRNA-22 promotes stress-induced cardiac dilation and contractile dysfunction. Circulation. 2012 Jun 05; 125(22):2751-61.
    View in: PubMed
    Score: 0.017
  37. PKC inhibition ameliorates the cardiac phenotype in a mouse model of myotonic dystrophy type 1. J Clin Invest. 2009 Dec; 119(12):3797-806.
    View in: PubMed
    Score: 0.014
  38. NFATc2 is a necessary mediator of calcineurin-dependent cardiac hypertrophy and heart failure. J Biol Chem. 2008 Aug 08; 283(32):22295-303.
    View in: PubMed
    Score: 0.013
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.