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XANDER WEHRENS to Atrial Fibrillation

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This is a "connection" page, showing publications XANDER WEHRENS has written about Atrial Fibrillation.
XANDER WEHRENS
Connection Strength
12.954
Atrial Fibrillation
  1. Multiomic and electrophysiologic analyses reveal that an inherited MRC2 variant causes fibroblast dysfunction and increased atrial fibrillation susceptibility. Am J Physiol Heart Circ Physiol. 2025 Nov 01; 329(5):H1055-H1071.
    View in: PubMed
    Score: 0.571
  2. Atrial fibroblast-derived macrophage migration inhibitory factor promotes atrial macrophage accumulation in postoperative atrial fibrillation. JCI Insight. 2025 Sep 23; 10(18).
    View in: PubMed
    Score: 0.567
  3. Mechanisms underlying atrial fibrillation in chronic kidney disease. J Mol Cell Cardiol. 2025 Aug; 205:37-51.
    View in: PubMed
    Score: 0.560
  4. Diabetes and Atrial Fibrillation: Insight From Basic to Translational Science Into the Mechanisms and Management. J Cardiovasc Electrophysiol. 2025 Oct; 36(10):2755-2766.
    View in: PubMed
    Score: 0.552
  5. Macrophage-mediated IL-6 signaling drives ryanodine receptor-2 calcium leak in postoperative atrial fibrillation. J Clin Invest. 2025 May 01; 135(9).
    View in: PubMed
    Score: 0.550
  6. Hypertension and Atrial Fibrillation: Insight From Basic to Translational Science Into the Mechanisms and Management. J Cardiovasc Electrophysiol. 2025 Oct; 36(10):2712-2719.
    View in: PubMed
    Score: 0.550
  7. A mechanistic LNK between inflammation and atrial fibrillation? Cardiovasc Res. 2024 07 02; 120(8):814-816.
    View in: PubMed
    Score: 0.524
  8. Tachycardia and Atrial Fibrillation-Related Cardiomyopathies: Potential Mechanisms and Current Therapies. JACC Heart Fail. 2024 Apr; 12(4):605-615.
    View in: PubMed
    Score: 0.507
  9. Kinase Inhibitors and Atrial Fibrillation: Mechanisms of Action and Clinical Implications. JACC Clin Electrophysiol. 2023 04; 9(4):591-602.
    View in: PubMed
    Score: 0.477
  10. Mouse models of spontaneous atrial fibrillation. Mamm Genome. 2023 Jun; 34(2):298-311.
    View in: PubMed
    Score: 0.464
  11. Diagnosing atrial fibrillation: Can we do better than the ECG? Heart Rhythm. 2022 09; 19(9):1459-1460.
    View in: PubMed
    Score: 0.455
  12. Gut microbiota: a key regulator of ageing-associated atrial fibrillation? Cardiovasc Res. 2022 02 21; 118(3):657-659.
    View in: PubMed
    Score: 0.445
  13. Atrial-Specific LKB1 Knockdown Represents a Novel Mouse Model of Atrial Cardiomyopathy With Spontaneous Atrial Fibrillation. Circulation. 2021 09 14; 144(11):909-912.
    View in: PubMed
    Score: 0.432
  14. Junctophilin-2 expression rescues atrial dysfunction through polyadic junctional membrane complex biogenesis. JCI Insight. 2019 06 20; 4(12).
    View in: PubMed
    Score: 0.370
  15. Genetics of atrial fibrillation: an update. Curr Opin Cardiol. 2018 05; 33(3):304-310.
    View in: PubMed
    Score: 0.342
  16. Calcium-mediated cellular triggered activity in atrial fibrillation. J Physiol. 2017 06 15; 595(12):4001-4008.
    View in: PubMed
    Score: 0.317
  17. PITX2: a master regulator of cardiac channelopathy in atrial fibrillation? Cardiovasc Res. 2016 Mar 01; 109(3):345-7.
    View in: PubMed
    Score: 0.292
  18. Expression and function of Kv1.1 potassium channels in human atria from patients with atrial fibrillation. Basic Res Cardiol. 2015 Sep; 110(5):505.
    View in: PubMed
    Score: 0.281
  19. Progress toward the prevention and treatment of atrial fibrillation: A summary of the Heart Rhythm Society Research Forum on the Treatment and Prevention of Atrial Fibrillation, Washington, DC, December 9-10, 2013. Heart Rhythm. 2015 Jan; 12(1):e5-e29.
    View in: PubMed
    Score: 0.269
  20. Impaired local regulation of ryanodine receptor type 2 by protein phosphatase 1 promotes atrial fibrillation. Cardiovasc Res. 2014 Jul 01; 103(1):178-87.
    View in: PubMed
    Score: 0.259
  21. Mutation E169K in junctophilin-2 causes atrial fibrillation due to impaired RyR2 stabilization. J Am Coll Cardiol. 2013 Nov 19; 62(21):2010-9.
    View in: PubMed
    Score: 0.247
  22. Chronic exercise: a contributing factor to atrial fibrillation? J Am Coll Cardiol. 2013 Jul 02; 62(1):78-80.
    View in: PubMed
    Score: 0.241
  23. Inhibition of CaMKII phosphorylation of RyR2 prevents induction of atrial fibrillation in FKBP12.6 knockout mice. Circ Res. 2012 Feb 03; 110(3):465-70.
    View in: PubMed
    Score: 0.219
  24. The ryanodine receptor channel as a molecular motif in atrial fibrillation: pathophysiological and therapeutic implications. Cardiovasc Res. 2011 Mar 01; 89(4):734-43.
    View in: PubMed
    Score: 0.203
  25. Calmodulin kinase II, sarcoplasmic reticulum Ca2+ leak, and atrial fibrillation. Trends Cardiovasc Med. 2010 Jan; 20(1):30-4.
    View in: PubMed
    Score: 0.192
  26. Intracellular calcium leak due to FKBP12.6 deficiency in mice facilitates the inducibility of atrial fibrillation. Heart Rhythm. 2008 Jul; 5(7):1047-54.
    View in: PubMed
    Score: 0.170
  27. Pathways to precision medicine: deciphering the secrets of physiological and pathological atrial enlargement. Clin Sci (Lond). 2024 Sep 18; 138(18):1173-1177.
    View in: PubMed
    Score: 0.133
  28. Atrial proteomic profiling reveals a switch towards profibrotic gene expression program in CREM-Ib?C-X mice with persistent atrial fibrillation. J Mol Cell Cardiol. 2024 05; 190:1-12.
    View in: PubMed
    Score: 0.129
  29. Chronic kidney disease promotes atrial fibrillation via inflammasome pathway activation. J Clin Invest. 2023 10 02; 133(19).
    View in: PubMed
    Score: 0.124
  30. PPP1R12C Promotes Atrial Hypocontractility in Atrial Fibrillation. Circ Res. 2023 10 13; 133(9):758-771.
    View in: PubMed
    Score: 0.124
  31. Downregulation of FKBP5 Promotes Atrial Arrhythmogenesis. Circ Res. 2023 06 23; 133(1):e1-e16.
    View in: PubMed
    Score: 0.121
  32. Genetic inhibition of nuclear factor of activated T-cell c2 prevents atrial fibrillation in CREM transgenic mice. Cardiovasc Res. 2022 10 21; 118(13):2805-2818.
    View in: PubMed
    Score: 0.117
  33. Common disease-promoting signalling pathways in heart failure and atrial fibrillation: putative underlying mechanisms and potential therapeutic consequences. Cardiovasc Res. 2022 08 24; 118(11):2397-2399.
    View in: PubMed
    Score: 0.115
  34. SPEG: a key regulator of cardiac calcium homeostasis. Cardiovasc Res. 2021 08 29; 117(10):2175-2185.
    View in: PubMed
    Score: 0.108
  35. Oxidized CaMKII and O-GlcNAcylation cause increased atrial fibrillation in diabetic mice by distinct mechanisms. J Clin Invest. 2021 01 19; 131(2).
    View in: PubMed
    Score: 0.103
  36. Atrial Myocyte NLRP3/CaMKII Nexus Forms a Substrate for Postoperative Atrial Fibrillation. Circ Res. 2020 09 25; 127(8):1036-1055.
    View in: PubMed
    Score: 0.100
  37. Loss of SPEG Inhibitory Phosphorylation of Ryanodine Receptor Type-2 Promotes Atrial Fibrillation. Circulation. 2020 09 22; 142(12):1159-1172.
    View in: PubMed
    Score: 0.100
  38. Wolff-Parkinson-White syndrome: De novo variants and evidence for mutational burden in genes associated with atrial fibrillation. Am J Med Genet A. 2020 06; 182(6):1387-1399.
    View in: PubMed
    Score: 0.098
  39. Targeting pathological leak of ryanodine receptors: preclinical progress and the potential impact on treatments for cardiac arrhythmias and heart failure. Expert Opin Ther Targets. 2020 01; 24(1):25-36.
    View in: PubMed
    Score: 0.096
  40. Calmodulin kinase II regulates atrial myocyte late sodium current, calcium handling, and atrial arrhythmia. Heart Rhythm. 2020 03; 17(3):503-511.
    View in: PubMed
    Score: 0.095
  41. Loss of Protein Phosphatase 1 Regulatory Subunit PPP1R3A Promotes Atrial Fibrillation. Circulation. 2019 08 20; 140(8):681-693.
    View in: PubMed
    Score: 0.092
  42. Enhanced Cardiomyocyte NLRP3 Inflammasome Signaling Promotes Atrial Fibrillation. Circulation. 2018 11 13; 138(20):2227-2242.
    View in: PubMed
    Score: 0.089
  43. Serine/Threonine Phosphatases in Atrial Fibrillation. J Mol Cell Cardiol. 2017 02; 103:110-120.
    View in: PubMed
    Score: 0.078
  44. Regulating the regulator: Insights into the cardiac protein phosphatase 1 interactome. J Mol Cell Cardiol. 2016 Dec; 101:165-172.
    View in: PubMed
    Score: 0.076
  45. The value of basic research insights into atrial fibrillation mechanisms as a guide to therapeutic innovation: a critical analysis. Cardiovasc Res. 2016 Apr 01; 109(4):467-79.
    View in: PubMed
    Score: 0.073
  46. Neuronally released vasoactive intestinal polypeptide alters atrial electrophysiological properties and may promote atrial fibrillation. Heart Rhythm. 2015 Jun; 12(6):1352-61.
    View in: PubMed
    Score: 0.069
  47. Identification of microRNA-mRNA dysregulations in paroxysmal atrial fibrillation. Int J Cardiol. 2015 Apr 01; 184:190-197.
    View in: PubMed
    Score: 0.068
  48. Alterations in the interactome of serine/threonine protein phosphatase type-1 in atrial fibrillation patients. J Am Coll Cardiol. 2015 Jan 20; 65(2):163-73.
    View in: PubMed
    Score: 0.068
  49. Increased atrial arrhythmia susceptibility induced by intense endurance exercise in mice requires TNFa. Nat Commun. 2015 Jan 19; 6:6018.
    View in: PubMed
    Score: 0.068
  50. Loss of microRNA-106b-25 cluster promotes atrial fibrillation by enhancing ryanodine receptor type-2 expression and calcium release. Circ Arrhythm Electrophysiol. 2014 Dec; 7(6):1214-22.
    View in: PubMed
    Score: 0.067
  51. Pitx2-microRNA pathway that delimits sinoatrial node development and inhibits predisposition to atrial fibrillation. Proc Natl Acad Sci U S A. 2014 Jun 24; 111(25):9181-6.
    View in: PubMed
    Score: 0.065
  52. Ryanodine receptor-mediated calcium leak drives progressive development of an atrial fibrillation substrate in a transgenic mouse model. Circulation. 2014 Mar 25; 129(12):1276-1285.
    View in: PubMed
    Score: 0.063
  53. Cellular and molecular mechanisms of atrial arrhythmogenesis in patients with paroxysmal atrial fibrillation. Circulation. 2014 Jan 14; 129(2):145-156.
    View in: PubMed
    Score: 0.063
  54. Oxidized Ca(2+)/calmodulin-dependent protein kinase II triggers atrial fibrillation. Circulation. 2013 Oct 15; 128(16):1748-57.
    View in: PubMed
    Score: 0.062
  55. Enhanced sarcoplasmic reticulum Ca2+ leak and increased Na+-Ca2+ exchanger function underlie delayed afterdepolarizations in patients with chronic atrial fibrillation. Circulation. 2012 May 01; 125(17):2059-70.
    View in: PubMed
    Score: 0.056
  56. Overexpression of cAMP-response element modulator causes abnormal growth and development of the atrial myocardium resulting in a substrate for sustained atrial fibrillation in mice. Int J Cardiol. 2013 Jun 20; 166(2):366-74.
    View in: PubMed
    Score: 0.055
  57. Defects in ankyrin-based membrane protein targeting pathways underlie atrial fibrillation. Circulation. 2011 Sep 13; 124(11):1212-22.
    View in: PubMed
    Score: 0.054
  58. CaMKII regulation of the cardiac ryanodine receptor and sarcoplasmic reticulum calcium release. Heart Rhythm. 2011 Feb; 8(2):323-5.
    View in: PubMed
    Score: 0.051
  59. Calmodulin kinase II-mediated sarcoplasmic reticulum Ca2+ leak promotes atrial fibrillation in mice. J Clin Invest. 2009 Jul; 119(7):1940-51.
    View in: PubMed
    Score: 0.046
  60. Defective cardiac ryanodine receptor regulation during atrial fibrillation. Circulation. 2005 Apr 26; 111(16):2025-32.
    View in: PubMed
    Score: 0.035
  61. Paracrine signalling by cardiac calcitonin controls atrial fibrogenesis and arrhythmia. Nature. 2020 11; 587(7834):460-465.
    View in: PubMed
    Score: 0.025
  62. Pitx2 prevents susceptibility to atrial arrhythmias by inhibiting left-sided pacemaker specification. Proc Natl Acad Sci U S A. 2010 May 25; 107(21):9753-8.
    View in: PubMed
    Score: 0.012
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Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.