WILLIAM MITCH to Signal Transduction
This is a "connection" page, showing publications WILLIAM MITCH has written about Signal Transduction.
Connection Strength
1.249
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Targeting the myostatin signaling pathway to treat muscle wasting diseases. Curr Opin Support Palliat Care. 2011 Dec; 5(4):334-41.
Score: 0.146
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Endogenous glucocorticoids and impaired insulin signaling are both required to stimulate muscle wasting under pathophysiological conditions in mice. J Clin Invest. 2009 Oct; 119(10):3059-69.
Score: 0.125
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Cellular signals activating muscle proteolysis in chronic kidney disease: a two-stage process. Int J Biochem Cell Biol. 2005 Oct; 37(10):2147-55.
Score: 0.095
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Identification of pathways controlling muscle protein metabolism in uremia and other catabolic conditions. Curr Opin Nephrol Hypertens. 2005 Jul; 14(4):378-82.
Score: 0.094
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Mechanisms Regulating Muscle Protein Synthesis in CKD. J Am Soc Nephrol. 2020 11; 31(11):2573-2587.
Score: 0.067
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Stat3 activation induces insulin resistance via a muscle-specific E3 ubiquitin ligase Fbxo40. Am J Physiol Endocrinol Metab. 2020 05 01; 318(5):E625-E635.
Score: 0.065
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Parathyroid hormone stimulates adipose tissue browning: a pathway to muscle wasting. Curr Opin Clin Nutr Metab Care. 2017 May; 20(3):153-157.
Score: 0.053
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Mechanisms of muscle wasting in chronic kidney disease. Nat Rev Nephrol. 2014 Sep; 10(9):504-16.
Score: 0.044
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Stat3 activation links a C/EBPd to myostatin pathway to stimulate loss of muscle mass. Cell Metab. 2013 Sep 03; 18(3):368-79.
Score: 0.041
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Muscle wasting from kidney failure-a model for catabolic conditions. Int J Biochem Cell Biol. 2013 Oct; 45(10):2230-8.
Score: 0.041
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Signal regulatory protein-a interacts with the insulin receptor contributing to muscle wasting in chronic kidney disease. Kidney Int. 2013 Aug; 84(2):308-16.
Score: 0.040
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Angiotensin II upregulates protein phosphatase 2Ca and inhibits AMP-activated protein kinase signaling and energy balance leading to skeletal muscle wasting. Hypertension. 2011 Oct; 58(4):643-9.
Score: 0.036
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Pharmacological inhibition of myostatin suppresses systemic inflammation and muscle atrophy in mice with chronic kidney disease. FASEB J. 2011 May; 25(5):1653-63.
Score: 0.034
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Satellite cell dysfunction and impaired IGF-1 signaling cause CKD-induced muscle atrophy. J Am Soc Nephrol. 2010 Mar; 21(3):419-27.
Score: 0.032
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PTEN expression contributes to the regulation of muscle protein degradation in diabetes. Diabetes. 2007 Oct; 56(10):2449-56.
Score: 0.027
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Proteolytic mechanisms, not malnutrition, cause loss of muscle mass in kidney failure. J Ren Nutr. 2006 Jul; 16(3):208-11.
Score: 0.025
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Insulin resistance accelerates muscle protein degradation: Activation of the ubiquitin-proteasome pathway by defects in muscle cell signaling. Endocrinology. 2006 Sep; 147(9):4160-8.
Score: 0.025
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Chronic kidney disease causes defects in signaling through the insulin receptor substrate/phosphatidylinositol 3-kinase/Akt pathway: implications for muscle atrophy. J Am Soc Nephrol. 2006 May; 17(5):1388-94.
Score: 0.025
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Myokine SIRPa exacerbates kidney disease in diabetes. JCI Insight. 2026 02 09; 11(3).
Score: 0.024
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Muscle-specific expression of IGF-1 blocks angiotensin II-induced skeletal muscle wasting. J Clin Invest. 2005 Feb; 115(2):451-8.
Score: 0.023
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Strategies for suppressing muscle atrophy in chronic kidney disease: mechanisms activating distinct proteolytic systems. J Ren Nutr. 2005 Jan; 15(1):23-7.
Score: 0.023
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Regulation of muscle protein degradation: coordinated control of apoptotic and ubiquitin-proteasome systems by phosphatidylinositol 3 kinase. J Am Soc Nephrol. 2004 Jun; 15(6):1537-45.
Score: 0.022
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Decreased Jagged1 expression in vascular smooth muscle cells delays endothelial regeneration in arteriovenous graft. Cardiovasc Res. 2020 11 01; 116(13):2142-2155.
Score: 0.017
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Signal regulatory protein alpha initiates cachexia through muscle to adipose tissue crosstalk. J Cachexia Sarcopenia Muscle. 2019 12; 10(6):1210-1227.
Score: 0.016
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Notch signaling in bone marrow-derived FSP-1?cells initiates neointima formation in arteriovenous?fistulas. Kidney Int. 2019 06; 95(6):1347-1358.
Score: 0.015
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The IL-4 receptor a has a critical role in bone marrow-derived fibroblast activation and renal fibrosis. Kidney Int. 2017 12; 92(6):1433-1443.
Score: 0.013
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AMP-activated protein kinase/myocardin-related transcription factor-A signaling regulates fibroblast activation and renal fibrosis. Kidney Int. 2018 01; 93(1):81-94.
Score: 0.013
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JAK3/STAT6 Stimulates Bone Marrow-Derived Fibroblast Activation in Renal Fibrosis. J Am Soc Nephrol. 2015 Dec; 26(12):3060-71.
Score: 0.012
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Migration of smooth muscle cells from the arterial anastomosis of arteriovenous fistulas requires Notch activation to form neointima. Kidney Int. 2015 Sep; 88(3):490-502.
Score: 0.011
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MicroRNA-29 induces cellular senescence in aging muscle through multiple signaling pathways. Aging (Albany NY). 2014 Mar; 6(3):160-75.
Score: 0.011
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Blocking Notch in endothelial cells prevents arteriovenous fistula failure despite CKD. J Am Soc Nephrol. 2014 Apr; 25(4):773-83.
Score: 0.011
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Molecular mechanisms and signaling pathways of angiotensin II-induced muscle wasting: potential therapeutic targets for cardiac cachexia. Int J Biochem Cell Biol. 2013 Oct; 45(10):2322-32.
Score: 0.010
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Myostatin/activin pathway antagonism: molecular basis and therapeutic potential. Int J Biochem Cell Biol. 2013 Oct; 45(10):2333-47.
Score: 0.010
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Ubiquitin (UbC) expression in muscle cells is increased by glucocorticoids through a mechanism involving Sp1 and MEK1. J Biol Chem. 2002 May 10; 277(19):16673-81.
Score: 0.005