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WILLIAM LAGOR to Animals

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This is a "connection" page, showing publications WILLIAM LAGOR has written about Animals.
WILLIAM LAGOR
Connection Strength
0.915
Animals
  1. In vivo expansion of gene-targeted hepatocytes through transient inhibition of an essential gene. Sci Transl Med. 2025 Feb 12; 17(785):eadk3920.
    View in: PubMed
    Score: 0.051
  2. A comprehensive atlas of AAV tropism in the mouse. Mol Ther. 2025 Mar 05; 33(3):1282-1299.
    View in: PubMed
    Score: 0.051
  3. Liver directed adeno-associated viral vectors to treat metabolic disease. J Inherit Metab Dis. 2024 01; 47(1):22-40.
    View in: PubMed
    Score: 0.046
  4. Treating Cardiovascular Disease with Liver Genome Engineering. Curr Atheroscler Rep. 2022 02; 24(2):75-84.
    View in: PubMed
    Score: 0.042
  5. Intestinal Deletion of 3-Hydroxy-3-Methylglutaryl-Coenzyme A Reductase Promotes Expansion of the Resident Stem Cell Compartment. Arterioscler Thromb Vasc Biol. 2022 04; 42(4):381-394.
    View in: PubMed
    Score: 0.042
  6. In Vivo Gene Editing in Lipid and Atherosclerosis Research. Methods Mol Biol. 2022; 2419:673-713.
    View in: PubMed
    Score: 0.041
  7. Depletion of essential isoprenoids and ER stress induction following acute liver-specific deletion of HMG-CoA reductase. J Lipid Res. 2020 Dec; 61(12):1675-1686.
    View in: PubMed
    Score: 0.038
  8. Recent advances in genome editing for cardiovascular disease. Curr Opin Cardiol. 2020 05; 35(3):242-248.
    View in: PubMed
    Score: 0.037
  9. AAV-CRISPR Gene Editing Is Negated by Pre-existing Immunity to Cas9. Mol Ther. 2020 Jun 03; 28(6):1432-1441.
    View in: PubMed
    Score: 0.037
  10. CRISPR: a promising tool for lipid physiology and therapeutics. Curr Opin Lipidol. 2019 06; 30(3):172-176.
    View in: PubMed
    Score: 0.035
  11. Gene Delivery in Lipid Research and Therapies. Methodist Debakey Cardiovasc J. 2019 Jan-Mar; 15(1):62-69.
    View in: PubMed
    Score: 0.034
  12. Somatic Editing of Ldlr With Adeno-Associated Viral-CRISPR Is an Efficient Tool for Atherosclerosis Research. Arterioscler Thromb Vasc Biol. 2018 09; 38(9):1997-2006.
    View in: PubMed
    Score: 0.033
  13. Somatic genome editing with CRISPR/Cas9 generates and corrects a metabolic disease. Sci Rep. 2017 03 16; 7:44624.
    View in: PubMed
    Score: 0.030
  14. Genetic manipulation of the ApoF/Stat2 locus supports an important role for type I interferon signaling in atherosclerosis. Atherosclerosis. 2014 Mar; 233(1):234-41.
    View in: PubMed
    Score: 0.024
  15. Adeno-associated viruses as liver-directed gene delivery vehicles: focus on lipoprotein metabolism. Methods Mol Biol. 2013; 1027:273-307.
    View in: PubMed
    Score: 0.022
  16. The effects of apolipoprotein F deficiency on high density lipoprotein cholesterol metabolism in mice. PLoS One. 2012; 7(2):e31616.
    View in: PubMed
    Score: 0.021
  17. Phospholipidation of HDL--how much is too much? Clin Chem. 2011 Jan; 57(1):4-6.
    View in: PubMed
    Score: 0.019
  18. Overexpression of apolipoprotein F reduces HDL cholesterol levels in vivo. Arterioscler Thromb Vasc Biol. 2009 Jan; 29(1):40-6.
    View in: PubMed
    Score: 0.017
  19. Functional analysis of the hepatic HMG-CoA reductase promoter by in vivo electroporation. Exp Biol Med (Maywood). 2007 Mar; 232(3):353-61.
    View in: PubMed
    Score: 0.015
  20. Diabetes alters the occupancy of the hepatic 3-hydroxy-3-methylglutaryl-CoA reductase promoter. J Biol Chem. 2005 Nov 04; 280(44):36601-8.
    View in: PubMed
    Score: 0.013
  21. MBNL overexpression rescues cardiac phenotypes in a myotonic dystrophy type 1 heart mouse model. J Clin Invest. 2025 Feb 11; 135(7).
    View in: PubMed
    Score: 0.013
  22. Speg interactions that regulate the stability of excitation-contraction coupling protein complexes in triads and dyads. Commun Biol. 2023 09 14; 6(1):942.
    View in: PubMed
    Score: 0.012
  23. Targeting AAV vectors to the central nervous system by engineering capsid-receptor interactions that enable crossing of the blood-brain barrier. PLoS Biol. 2023 07; 21(7):e3002112.
    View in: PubMed
    Score: 0.012
  24. High levels of lipoprotein(a) in transgenic mice exacerbate atherosclerosis and promote vulnerable plaque features in a sex-specific manner. Atherosclerosis. 2023 11; 384:117150.
    View in: PubMed
    Score: 0.011
  25. Rescue of glutaric aciduria type I in mice by liver-directed therapies. Sci Transl Med. 2023 04 19; 15(692):eadf4086.
    View in: PubMed
    Score: 0.011
  26. Adeno-Associated virus 8 delivers an immunomodulatory peptide to mouse liver more efficiently than to rat liver. PLoS One. 2023; 18(4):e0283996.
    View in: PubMed
    Score: 0.011
  27. In vivo editing of the pan-endothelium by immunity evading simian adenoviral vector. Biomed Pharmacother. 2023 Feb; 158:114189.
    View in: PubMed
    Score: 0.011
  28. Temporospatial regulation of intraflagellar transport is required for the endochondral ossification in mice. Dev Biol. 2022 02; 482:91-100.
    View in: PubMed
    Score: 0.010
  29. AAV5 delivery of CRISPR-Cas9 supports effective genome editing in mouse lung airway. Mol Ther. 2022 Jan 05; 30(1):238-243.
    View in: PubMed
    Score: 0.010
  30. The NIH Somatic Cell Genome Editing program. Nature. 2021 04; 592(7853):195-204.
    View in: PubMed
    Score: 0.010
  31. TFEB regulates murine liver cell fate during development and regeneration. Nat Commun. 2020 05 18; 11(1):2461.
    View in: PubMed
    Score: 0.009
  32. Integrating Mouse and Human Genetic Data to Move beyond GWAS and Identify Causal Genes in Cholesterol Metabolism. Cell Metab. 2020 04 07; 31(4):741-754.e5.
    View in: PubMed
    Score: 0.009
  33. Replacing Saturated Fat With Unsaturated Fat in Western Diet Reduces Foamy Monocytes and Atherosclerosis in Male Ldlr-/- Mice. Arterioscler Thromb Vasc Biol. 2020 01; 40(1):72-85.
    View in: PubMed
    Score: 0.009
  34. Depletion of Endothelial Prolyl Hydroxylase Domain Protein 2 and 3 Promotes Cardiomyocyte Proliferation and Prevents Ventricular Failure Induced by Myocardial Infarction. Circulation. 2019 07 30; 140(5):440-442.
    View in: PubMed
    Score: 0.009
  35. Atrial-Specific Gene Delivery Using an Adeno-Associated Viral Vector. Circ Res. 2019 01 18; 124(2):256-262.
    View in: PubMed
    Score: 0.008
  36. In Vivo Ryr2 Editing Corrects Catecholaminergic Polymorphic Ventricular Tachycardia. Circ Res. 2018 Sep 28; 123(8):953-963.
    View in: PubMed
    Score: 0.008
  37. Rapid Disruption of Genes Specifically in Livers of Mice Using Multiplex CRISPR/Cas9 Editing. Gastroenterology. 2018 12; 155(6):1967-1970.e6.
    View in: PubMed
    Score: 0.008
  38. TAp63 contributes to sexual dimorphism in POMC neuron functions and energy homeostasis. Nat Commun. 2018 04 18; 9(1):1544.
    View in: PubMed
    Score: 0.008
  39. CRISPR/Cas9: at the cutting edge of hepatology. Gut. 2017 07; 66(7):1329-1340.
    View in: PubMed
    Score: 0.008
  40. A chemical chaperone improves muscle function in mice with a RyR1 mutation. Nat Commun. 2017 03 24; 8:14659.
    View in: PubMed
    Score: 0.007
  41. Overexpression and deletion of phospholipid transfer protein reduce HDL mass and cholesterol efflux capacity but not macrophage reverse cholesterol transport. J Lipid Res. 2017 04; 58(4):731-741.
    View in: PubMed
    Score: 0.007
  42. Streptococcal serum opacity factor promotes cholesterol ester metabolism and bile acid secretion in vitro and in vivo. Biochim Biophys Acta. 2016 Mar; 1861(3):196-204.
    View in: PubMed
    Score: 0.007
  43. Ca2+ Binding/Permeation via Calcium Channel, CaV1.1, Regulates the Intracellular Distribution of the Fatty Acid Transport Protein, CD36, and Fatty Acid Metabolism. J Biol Chem. 2015 Sep 25; 290(39):23751-65.
    View in: PubMed
    Score: 0.007
  44. Development and rescue of human familial hypercholesterolaemia in a xenograft mouse model. Nat Commun. 2015 Jun 17; 6:7339.
    View in: PubMed
    Score: 0.007
  45. Targeting adipose tissue via systemic gene therapy. Gene Ther. 2014 Jul; 21(7):653-61.
    View in: PubMed
    Score: 0.006
  46. Lipidomic analyses of female mice lacking hepatic lipase and endothelial lipase indicate selective modulation of plasma lipid species. Lipids. 2014 Jun; 49(6):505-15.
    View in: PubMed
    Score: 0.006
  47. Adeno-associated virus serotype 8 gene therapy leads to significant lowering of plasma cholesterol levels in humanized mouse models of homozygous and heterozygous familial hypercholesterolemia. Hum Gene Ther. 2013 Jan; 24(1):19-26.
    View in: PubMed
    Score: 0.006
  48. Thyroid hormone enhances the ability of serum to accept cellular cholesterol via the ABCA1 transporter. Atherosclerosis. 2011 Sep; 218(1):77-82.
    View in: PubMed
    Score: 0.005
  49. Overexpression of apolipoprotein O does not impact on plasma HDL levels or functionality in human apolipoprotein A-I transgenic mice. Biochim Biophys Acta. 2011 Apr; 1811(4):294-9.
    View in: PubMed
    Score: 0.005
  50. Trib1 is a lipid- and myocardial infarction-associated gene that regulates hepatic lipogenesis and VLDL production in mice. J Clin Invest. 2010 Dec; 120(12):4410-4.
    View in: PubMed
    Score: 0.005
  51. Impact of combined deficiency of hepatic lipase and endothelial lipase on the metabolism of both high-density lipoproteins and apolipoprotein B-containing lipoproteins. Circ Res. 2010 Aug 06; 107(3):357-64.
    View in: PubMed
    Score: 0.005
  52. Technological advances in the study of HLA-DRA promoter regulation: extending the functions of CIITA, Oct-1, Rb, and RFX. Acta Biochim Biophys Sin (Shanghai). 2009 Mar; 41(3):198-205.
    View in: PubMed
    Score: 0.004
  53. Identification of insulin-responsive regions in the HMG-CoA reductase promoter. Biochem Biophys Res Commun. 2004 Jun 11; 318(4):814-8.
    View in: PubMed
    Score: 0.003
Connection Strength

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