MAKOTO FUKUDA to Animals
This is a "connection" page, showing publications MAKOTO FUKUDA has written about Animals.
Connection Strength
0.613
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Low-dose metformin requires brain Rap1 for its antidiabetic action. Sci Adv. 2025 Aug; 11(31):eadu3700.
Score: 0.053
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Advanced glycation end products alter the structural integrity, increase the permeability and transform the biocompatibility of collagen within the peritoneal membrane. Hum Cell. 2025 May 12; 38(4):99.
Score: 0.052
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The small GTPase Rap1 in POMC neurons regulates leptin actions and glucose metabolism. Mol Metab. 2025 May; 95:102117.
Score: 0.051
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The Role of GIP Receptor in the CNS for the Pathogenesis of Obesity. Diabetes. 2021 09; 70(9):1929-1937.
Score: 0.040
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Rap1 in the VMH regulates glucose homeostasis. JCI Insight. 2021 06 08; 6(11).
Score: 0.040
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Gut Hormone GIP Induces Inflammation and Insulin Resistance in the Hypothalamus. Endocrinology. 2020 09 01; 161(9).
Score: 0.038
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Gut-derived GIP activates central Rap1 to impair neural leptin sensitivity during overnutrition. J Clin Invest. 2019 08 12; 129(9):3786-3791.
Score: 0.035
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Neuronal Rap1 Regulates Energy Balance, Glucose Homeostasis, and Leptin Actions. Cell Rep. 2016 09 13; 16(11):3003-3015.
Score: 0.029
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Central nervous control of energy and glucose balance: focus on the central melanocortin system. Ann N Y Acad Sci. 2011 Dec; 1243:1-14.
Score: 0.021
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Induction of leptin resistance by activation of cAMP-Epac signaling. Cell Metab. 2011 Mar 02; 13(3):331-9.
Score: 0.019
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Monitoring FoxO1 localization in chemically identified neurons. J Neurosci. 2008 Dec 10; 28(50):13640-8.
Score: 0.017
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Vestibular neurons link motion sickness, behavioural thermoregulation and metabolic balance in mice. Nat Metab. 2025 Apr; 7(4):742-758.
Score: 0.013
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Anoctamin 4 channel currents activate glucose-inhibited neurons in the mouse ventromedial hypothalamus during hypoglycemia. J Clin Invest. 2023 07 17; 133(14).
Score: 0.011
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Hypothalamic steroid receptor coactivator-2 regulates adaptations to fasting and overnutrition. Cell Rep. 2021 12 07; 37(10):110075.
Score: 0.010
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Barbadin Potentiates Long-Term Effects of Lorcaserin on POMC Neurons and Weight Loss. J Neurosci. 2021 06 30; 41(26):5734-5746.
Score: 0.010
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AgRP neurons trigger long-term potentiation and facilitate food seeking. Transl Psychiatry. 2021 01 05; 11(1):11.
Score: 0.010
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A POMC-originated circuit regulates stress-induced hypophagia, depression, and anhedonia. Mol Psychiatry. 2020 05; 25(5):1006-1021.
Score: 0.009
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A novel regulatory mechanism in the mitogen-activated protein (MAP) kinase cascade. Role of nuclear export signal of MAP kinase kinase. J Biol Chem. 1997 Dec 19; 272(51):32642-8.
Score: 0.008
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CRM1 is responsible for intracellular transport mediated by the nuclear export signal. Nature. 1997 Nov 20; 390(6657):308-11.
Score: 0.008
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Interaction of MAP kinase with MAP kinase kinase: its possible role in the control of nucleocytoplasmic transport of MAP kinase. EMBO J. 1997 Apr 15; 16(8):1901-8.
Score: 0.007
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Cytoplasmic localization of mitogen-activated protein kinase kinase directed by its NH2-terminal, leucine-rich short amino acid sequence, which acts as a nuclear export signal. J Biol Chem. 1996 Aug 16; 271(33):20024-8.
Score: 0.007
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PI3K in the ventromedial hypothalamic nucleus mediates estrogenic actions on energy expenditure in female mice. Sci Rep. 2016 Mar 18; 6:23459.
Score: 0.007
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The ERa-PI3K Cascade in Proopiomelanocortin Progenitor Neurons Regulates Feeding and Glucose Balance in Female Mice. Endocrinology. 2015 Dec; 156(12):4474-91.
Score: 0.007
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Induction of neurite outgrowth by MAP kinase in PC12 cells. Oncogene. 1995 Jul 20; 11(2):239-44.
Score: 0.007
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Meta-chlorophenylpiperazine enhances leptin sensitivity in diet-induced obese mice. Br J Pharmacol. 2015 Jul; 172(14):3510-21.
Score: 0.007
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Estrogens prevent metabolic dysfunctions induced by circadian disruptions in female mice. Endocrinology. 2015 Jun; 156(6):2114-23.
Score: 0.006
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Analysis of the Ras p21/mitogen-activated protein kinase signaling in vitro and in Xenopus oocytes. J Biol Chem. 1994 Dec 30; 269(52):33097-101.
Score: 0.006
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Xbp1s in Pomc neurons connects ER stress with energy balance and glucose homeostasis. Cell Metab. 2014 Sep 02; 20(3):471-82.
Score: 0.006
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Galanin-like peptide (GALP) neurone-specific phosphoinositide 3-kinase signalling regulates GALP mRNA levels in the hypothalamus of males and luteinising hormone levels in both sexes. J Neuroendocrinol. 2014 Jul; 26(7):426-38.
Score: 0.006
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Hepatocyte Toll-like receptor 4 regulates obesity-induced inflammation and insulin resistance. Nat Commun. 2014 May 12; 5:3878.
Score: 0.006
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Elevated resistin levels induce central leptin resistance and increased atherosclerotic progression in mice. Diabetologia. 2014 Jun; 57(6):1209-18.
Score: 0.006
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Central GLP-2 enhances hepatic insulin sensitivity via activating PI3K signaling in POMC neurons. Cell Metab. 2013 Jul 02; 18(1):86-98.
Score: 0.006
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5-HT2CRs expressed by pro-opiomelanocortin neurons regulate insulin sensitivity in liver. Nat Neurosci. 2010 Dec; 13(12):1457-9.
Score: 0.005
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Leptin induces phosphorylation of neuronal nitric oxide synthase in defined hypothalamic neurons. Endocrinology. 2010 Nov; 151(11):5415-27.
Score: 0.005
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SIRT1 deacetylase in POMC neurons is required for homeostatic defenses against diet-induced obesity. Cell Metab. 2010 Jul 07; 12(1):78-87.
Score: 0.005
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PI3K signaling in the ventromedial hypothalamic nucleus is required for normal energy homeostasis. Cell Metab. 2010 Jul 07; 12(1):88-95.
Score: 0.005
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Direct insulin and leptin action on pro-opiomelanocortin neurons is required for normal glucose homeostasis and fertility. Cell Metab. 2010 Apr 07; 11(4):286-97.
Score: 0.005
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Phosphatidyl inositol 3-kinase signaling in hypothalamic proopiomelanocortin neurons contributes to the regulation of glucose homeostasis. Endocrinology. 2009 Nov; 150(11):4874-82.
Score: 0.004
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Identification of a DAF-16 transcriptional target gene, scl-1, that regulates longevity and stress resistance in Caenorhabditis elegans. Curr Biol. 2003 Mar 04; 13(5):427-31.
Score: 0.003
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The GTPase Ran regulates chromosome positioning and nuclear envelope assembly in vivo. Curr Biol. 2002 Mar 19; 12(6):503-7.
Score: 0.003
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Identification and characterization of Caenorhabditis elegans gamma-tubulin in dividing cells and differentiated tissues. J Cell Sci. 2000 Nov; 113 Pt 21:3747-59.
Score: 0.002
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Identification of a nuclear export signal in MKK6, an activator of the carp p38 mitogen-activated protein kinases. Eur J Biochem. 2000 Jul; 267(14):4362-71.
Score: 0.002
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Nuclear export of MAP kinase (ERK) involves a MAP kinase kinase (MEK)-dependent active transport mechanism. J Cell Biol. 2000 Mar 06; 148(5):849-56.
Score: 0.002
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Two co-existing mechanisms for nuclear import of MAP kinase: passive diffusion of a monomer and active transport of a dimer. EMBO J. 1999 Oct 01; 18(19):5347-58.
Score: 0.002
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Phosphorylation of WAVE downstream of mitogen-activated protein kinase signaling. J Biol Chem. 1999 Sep 24; 274(39):27605-9.
Score: 0.002
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Involvement of CRM1, a nuclear export receptor, in mRNA export in mammalian cells and fission yeast. Genes Cells. 1999 May; 4(5):291-7.
Score: 0.002
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Control of the cell morphology and the S phase entry by mitogen-activated protein kinase kinase. A regulatory role of its n-terminal region. J Biol Chem. 1999 Apr 23; 274(17):11874-80.
Score: 0.002
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Nuclear export of cyclin B1 and its possible role in the DNA damage-induced G2 checkpoint. EMBO J. 1998 May 15; 17(10):2728-35.
Score: 0.002
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Nuclear export of actin: a novel mechanism regulating the subcellular localization of a major cytoskeletal protein. EMBO J. 1998 Mar 16; 17(6):1635-41.
Score: 0.002
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Direct triggering of the type I interferon system by virus infection: activation of a transcription factor complex containing IRF-3 and CBP/p300. EMBO J. 1998 Feb 16; 17(4):1087-95.
Score: 0.002
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Activation of mitogen-activated protein kinase and its activator by ras in intact cells and in a cell-free system. J Biol Chem. 1992 Oct 05; 267(28):20346-51.
Score: 0.001