Connection

SUZANNE FUQUA to Estrogen Receptor alpha

This is a "connection" page, showing publications SUZANNE FUQUA has written about Estrogen Receptor alpha.
Connection Strength

5.983
  1. ESR1 mutations and therapeutic resistance in metastatic breast cancer: progress and remaining challenges. Br J Cancer. 2022 02; 126(2):174-186.
    View in: PubMed
    Score: 0.580
  2. ESR1 mutations in breast cancer. Cancer. 2019 11 01; 125(21):3714-3728.
    View in: PubMed
    Score: 0.497
  3. The Impact of ESR1 Mutations on the Treatment of Metastatic Breast Cancer. Horm Cancer. 2018 08; 9(4):215-228.
    View in: PubMed
    Score: 0.457
  4. Androgen receptor promotes tamoxifen agonist activity by activation of EGFR in ERa-positive breast cancer. Breast Cancer Res Treat. 2015 Nov; 154(2):225-37.
    View in: PubMed
    Score: 0.383
  5. Estrogen receptor (ER) a mutations in breast cancer: hidden in plain sight. Breast Cancer Res Treat. 2014 Feb; 144(1):11-9.
    View in: PubMed
    Score: 0.340
  6. A hypersensitive estrogen receptor alpha mutation that alters dynamic protein interactions. Breast Cancer Res Treat. 2010 Jul; 122(2):381-93.
    View in: PubMed
    Score: 0.253
  7. Accelerated mammary maturation and differentiation, and delayed MMTVneu-induced tumorigenesis of K303R mutant ERalpha transgenic mice. Oncogene. 2009 Sep 10; 28(36):3177-87.
    View in: PubMed
    Score: 0.248
  8. Growth factor-induced resistance to tamoxifen is associated with a mutation of estrogen receptor alpha and its phosphorylation at serine 305. Breast Cancer Res Treat. 2010 Jan; 119(1):71-85.
    View in: PubMed
    Score: 0.241
  9. Hormone Action and Clinical Significance of the Estrogen Receptor a. Cancer Treat Res. 2009; 147:1-16.
    View in: PubMed
    Score: 0.239
  10. Association between the estrogen receptor alpha A908G mutation and outcomes in invasive breast cancer. Clin Cancer Res. 2007 Jun 01; 13(11):3235-43.
    View in: PubMed
    Score: 0.214
  11. Cooperative action of tamoxifen and c-Src inhibition in preventing the growth of estrogen receptor-positive human breast cancer cells. Mol Cancer Ther. 2006 Dec; 5(12):3023-31.
    View in: PubMed
    Score: 0.207
  12. Metastasis-associated protein 2 is a repressor of estrogen receptor alpha whose overexpression leads to estrogen-independent growth of human breast cancer cells. Mol Endocrinol. 2006 Sep; 20(9):2020-35.
    View in: PubMed
    Score: 0.199
  13. Phosphorylation of estrogen receptor alpha blocks its acetylation and regulates estrogen sensitivity. Cancer Res. 2004 Dec 15; 64(24):9199-208.
    View in: PubMed
    Score: 0.181
  14. Hormonal modulation of ESR1 mutant metastasis. Oncogene. 2021 02; 40(5):997-1011.
    View in: PubMed
    Score: 0.137
  15. RON signalling promotes therapeutic resistance in ESR1 mutant breast cancer. Br J Cancer. 2021 01; 124(1):191-206.
    View in: PubMed
    Score: 0.137
  16. Proteomic profiling identifies key coactivators utilized by mutant ERa proteins as potential new therapeutic targets. Oncogene. 2018 08; 37(33):4581-4598.
    View in: PubMed
    Score: 0.114
  17. Mutations in the estrogen receptor alpha hormone binding domain promote stem cell phenotype through notch activation in breast cancer cell lines. Cancer Lett. 2018 08 01; 428:12-20.
    View in: PubMed
    Score: 0.114
  18. Estrogen receptors in breast and bone: from virtue of remodeling to vileness of metastasis. Oncogene. 2017 08 10; 36(32):4527-4537.
    View in: PubMed
    Score: 0.106
  19. ESR1 Mutations in Cell-Free DNA of Breast Cancer: Predictive "Tip of the Iceberg". JAMA Oncol. 2016 10 01; 2(10):1315-1316.
    View in: PubMed
    Score: 0.102
  20. ESR1 mutations affect anti-proliferative responses to tamoxifen through enhanced cross-talk with IGF signaling. Breast Cancer Res Treat. 2016 06; 157(2):253-265.
    View in: PubMed
    Score: 0.100
  21. AR collaborates with ERa in aromatase inhibitor-resistant breast cancer. Breast Cancer Res Treat. 2014 Oct; 147(3):473-85.
    View in: PubMed
    Score: 0.089
  22. In vitro mechanism for downregulation of ER-a expression by epigallocatechin gallate in ER+/PR+ human breast cancer cells. Mol Nutr Food Res. 2013 May; 57(5):840-53.
    View in: PubMed
    Score: 0.079
  23. Estrogen receptor beta binds Sp1 and recruits a corepressor complex to the estrogen receptor alpha gene promoter. Breast Cancer Res Treat. 2012 Jul; 134(2):569-81.
    View in: PubMed
    Score: 0.076
  24. Lactoferrin-endothelin-1 axis contributes to the development and invasiveness of triple-negative breast cancer phenotypes. Cancer Res. 2011 Dec 01; 71(23):7259-69.
    View in: PubMed
    Score: 0.073
  25. Loss of Rho GDIa and resistance to tamoxifen via effects on estrogen receptor a. J Natl Cancer Inst. 2011 Apr 06; 103(7):538-52.
    View in: PubMed
    Score: 0.070
  26. Identification of a novel estrogen receptor-alpha variant and its upstream splicing regulator. Mol Endocrinol. 2010 May; 24(5):914-22.
    View in: PubMed
    Score: 0.065
  27. Phosphorylation of the mutant K303R estrogen receptor alpha at serine 305 affects aromatase inhibitor sensitivity. Oncogene. 2010 Apr 22; 29(16):2404-14.
    View in: PubMed
    Score: 0.064
  28. BRCA1 regulates acetylation and ubiquitination of estrogen receptor-alpha. Mol Endocrinol. 2010 Jan; 24(1):76-90.
    View in: PubMed
    Score: 0.063
  29. G protein-coupled receptor 30 expression is up-regulated by EGF and TGF alpha in estrogen receptor alpha-positive cancer cells. Mol Endocrinol. 2009 Nov; 23(11):1815-26.
    View in: PubMed
    Score: 0.063
  30. Expression of the K303R estrogen receptor-alpha breast cancer mutation induces resistance to an aromatase inhibitor via addiction to the PI3K/Akt kinase pathway. Cancer Res. 2009 Jun 01; 69(11):4724-32.
    View in: PubMed
    Score: 0.062
  31. Progesterone receptor B recruits a repressor complex to a half-PRE site of the estrogen receptor alpha gene promoter. Mol Endocrinol. 2009 Apr; 23(4):454-65.
    View in: PubMed
    Score: 0.060
  32. Elevated expression of mitogen-activated protein kinase phosphatase 3 in breast tumors: a mechanism of tamoxifen resistance. Cancer Res. 2006 Jun 01; 66(11):5950-9.
    View in: PubMed
    Score: 0.050
  33. Negative regulation of estrogen receptor alpha transactivation functions by LIM domain only 4 protein. Cancer Res. 2005 Nov 15; 65(22):10594-601.
    View in: PubMed
    Score: 0.048
  34. Estrogen receptor alpha-negative breast cancer tissues express significant levels of estrogen-independent transcription factors, ERbeta1 and ERbeta5: potential molecular targets for chemoprevention. Clin Cancer Res. 2005 Oct 15; 11(20):7579-85.
    View in: PubMed
    Score: 0.048
  35. Evidence that CRISPR-Cas9 Y537S-mutant expressing breast cancer cells activate Yes-associated protein 1 to driving the conversion of normal fibroblasts into cancer-associated fibroblasts. Cell Commun Signal. 2024 Nov 14; 22(1):545.
    View in: PubMed
    Score: 0.045
  36. Regulation of the estrogen receptor alpha minimal promoter by Sp1, USF-1 and ERalpha. Breast Cancer Res Treat. 2004 May; 85(2):111-20.
    View in: PubMed
    Score: 0.043
  37. Sp1 is essential for estrogen receptor alpha gene transcription. J Steroid Biochem Mol Biol. 2002 Sep; 82(1):7-18.
    View in: PubMed
    Score: 0.039
  38. A hypersensitive estrogen receptor-alpha mutation in premalignant breast lesions. Cancer Res. 2000 Aug 01; 60(15):4026-9.
    View in: PubMed
    Score: 0.033
  39. Leptin mediates tumor-stromal interactions that promote the invasive growth of breast cancer cells. Cancer Res. 2012 Mar 15; 72(6):1416-27.
    View in: PubMed
    Score: 0.019
  40. Dicer-mediated upregulation of BCRP confers tamoxifen resistance in human breast cancer cells. Clin Cancer Res. 2011 Oct 15; 17(20):6510-21.
    View in: PubMed
    Score: 0.018
  41. Resveratrol, through NF-Y/p53/Sin3/HDAC1 complex phosphorylation, inhibits estrogen receptor alpha gene expression via p38MAPK/CK2 signaling in human breast cancer cells. FASEB J. 2011 Oct; 25(10):3695-707.
    View in: PubMed
    Score: 0.018
  42. Direct acetylation of the estrogen receptor alpha hinge region by p300 regulates transactivation and hormone sensitivity. J Biol Chem. 2001 May 25; 276(21):18375-83.
    View in: PubMed
    Score: 0.009
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.