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SUZANNE FUQUA to Estrogen Receptor alpha

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This is a "connection" page, showing publications SUZANNE FUQUA has written about Estrogen Receptor alpha.
SUZANNE FUQUA
Connection Strength
6.432
Estrogen Receptor alpha
  1. Defective DNA Damage Response Is a Targetable Therapeutic Vulnerability in ESR1-Mutant Breast Cancer. Cancer Res. 2026 Apr 02; 86(7):1707-1723.
    View in: PubMed
    Score: 0.751
  2. ESR1 mutations and therapeutic resistance in metastatic breast cancer: progress and remaining challenges. Br J Cancer. 2022 02; 126(2):174-186.
    View in: PubMed
    Score: 0.551
  3. ESR1 mutations in breast cancer. Cancer. 2019 11 01; 125(21):3714-3728.
    View in: PubMed
    Score: 0.472
  4. The Impact of ESR1 Mutations on the Treatment of Metastatic Breast Cancer. Horm Cancer. 2018 08; 9(4):215-228.
    View in: PubMed
    Score: 0.434
  5. Androgen receptor promotes tamoxifen agonist activity by activation of EGFR in ERa-positive breast cancer. Breast Cancer Res Treat. 2015 Nov; 154(2):225-37.
    View in: PubMed
    Score: 0.364
  6. Estrogen receptor (ER) a mutations in breast cancer: hidden in plain sight. Breast Cancer Res Treat. 2014 Feb; 144(1):11-9.
    View in: PubMed
    Score: 0.323
  7. A hypersensitive estrogen receptor alpha mutation that alters dynamic protein interactions. Breast Cancer Res Treat. 2010 Jul; 122(2):381-93.
    View in: PubMed
    Score: 0.240
  8. Accelerated mammary maturation and differentiation, and delayed MMTVneu-induced tumorigenesis of K303R mutant ERalpha transgenic mice. Oncogene. 2009 Sep 10; 28(36):3177-87.
    View in: PubMed
    Score: 0.235
  9. Growth factor-induced resistance to tamoxifen is associated with a mutation of estrogen receptor alpha and its phosphorylation at serine 305. Breast Cancer Res Treat. 2010 Jan; 119(1):71-85.
    View in: PubMed
    Score: 0.229
  10. Hormone Action and Clinical Significance of the Estrogen Receptor a. Cancer Treat Res. 2009; 147:1-16.
    View in: PubMed
    Score: 0.227
  11. Association between the estrogen receptor alpha A908G mutation and outcomes in invasive breast cancer. Clin Cancer Res. 2007 Jun 01; 13(11):3235-43.
    View in: PubMed
    Score: 0.204
  12. Cooperative action of tamoxifen and c-Src inhibition in preventing the growth of estrogen receptor-positive human breast cancer cells. Mol Cancer Ther. 2006 Dec; 5(12):3023-31.
    View in: PubMed
    Score: 0.197
  13. Metastasis-associated protein 2 is a repressor of estrogen receptor alpha whose overexpression leads to estrogen-independent growth of human breast cancer cells. Mol Endocrinol. 2006 Sep; 20(9):2020-35.
    View in: PubMed
    Score: 0.189
  14. Phosphorylation of estrogen receptor alpha blocks its acetylation and regulates estrogen sensitivity. Cancer Res. 2004 Dec 15; 64(24):9199-208.
    View in: PubMed
    Score: 0.172
  15. Hormonal modulation of ESR1 mutant metastasis. Oncogene. 2021 02; 40(5):997-1011.
    View in: PubMed
    Score: 0.130
  16. RON signalling promotes therapeutic resistance in ESR1 mutant breast cancer. Br J Cancer. 2021 01; 124(1):191-206.
    View in: PubMed
    Score: 0.130
  17. Proteomic profiling identifies key coactivators utilized by mutant ERa proteins as potential new therapeutic targets. Oncogene. 2018 08; 37(33):4581-4598.
    View in: PubMed
    Score: 0.109
  18. Mutations in the estrogen receptor alpha hormone binding domain promote stem cell phenotype through notch activation in breast cancer cell lines. Cancer Lett. 2018 08 01; 428:12-20.
    View in: PubMed
    Score: 0.108
  19. Estrogen receptors in breast and bone: from virtue of remodeling to vileness of metastasis. Oncogene. 2017 08 10; 36(32):4527-4537.
    View in: PubMed
    Score: 0.101
  20. ESR1 Mutations in Cell-Free DNA of Breast Cancer: Predictive "Tip of the Iceberg". JAMA Oncol. 2016 10 01; 2(10):1315-1316.
    View in: PubMed
    Score: 0.097
  21. ESR1 mutations affect anti-proliferative responses to tamoxifen through enhanced cross-talk with IGF signaling. Breast Cancer Res Treat. 2016 06; 157(2):253-265.
    View in: PubMed
    Score: 0.095
  22. AR collaborates with ERa in aromatase inhibitor-resistant breast cancer. Breast Cancer Res Treat. 2014 Oct; 147(3):473-85.
    View in: PubMed
    Score: 0.084
  23. In vitro mechanism for downregulation of ER-a expression by epigallocatechin gallate in ER+/PR+ human breast cancer cells. Mol Nutr Food Res. 2013 May; 57(5):840-53.
    View in: PubMed
    Score: 0.075
  24. Estrogen receptor beta binds Sp1 and recruits a corepressor complex to the estrogen receptor alpha gene promoter. Breast Cancer Res Treat. 2012 Jul; 134(2):569-81.
    View in: PubMed
    Score: 0.072
  25. Lactoferrin-endothelin-1 axis contributes to the development and invasiveness of triple-negative breast cancer phenotypes. Cancer Res. 2011 Dec 01; 71(23):7259-69.
    View in: PubMed
    Score: 0.069
  26. Loss of Rho GDIa and resistance to tamoxifen via effects on estrogen receptor a. J Natl Cancer Inst. 2011 Apr 06; 103(7):538-52.
    View in: PubMed
    Score: 0.066
  27. Identification of a novel estrogen receptor-alpha variant and its upstream splicing regulator. Mol Endocrinol. 2010 May; 24(5):914-22.
    View in: PubMed
    Score: 0.062
  28. Phosphorylation of the mutant K303R estrogen receptor alpha at serine 305 affects aromatase inhibitor sensitivity. Oncogene. 2010 Apr 22; 29(16):2404-14.
    View in: PubMed
    Score: 0.061
  29. BRCA1 regulates acetylation and ubiquitination of estrogen receptor-alpha. Mol Endocrinol. 2010 Jan; 24(1):76-90.
    View in: PubMed
    Score: 0.060
  30. G protein-coupled receptor 30 expression is up-regulated by EGF and TGF alpha in estrogen receptor alpha-positive cancer cells. Mol Endocrinol. 2009 Nov; 23(11):1815-26.
    View in: PubMed
    Score: 0.060
  31. Expression of the K303R estrogen receptor-alpha breast cancer mutation induces resistance to an aromatase inhibitor via addiction to the PI3K/Akt kinase pathway. Cancer Res. 2009 Jun 01; 69(11):4724-32.
    View in: PubMed
    Score: 0.058
  32. Progesterone receptor B recruits a repressor complex to a half-PRE site of the estrogen receptor alpha gene promoter. Mol Endocrinol. 2009 Apr; 23(4):454-65.
    View in: PubMed
    Score: 0.057
  33. Elevated expression of mitogen-activated protein kinase phosphatase 3 in breast tumors: a mechanism of tamoxifen resistance. Cancer Res. 2006 Jun 01; 66(11):5950-9.
    View in: PubMed
    Score: 0.047
  34. Negative regulation of estrogen receptor alpha transactivation functions by LIM domain only 4 protein. Cancer Res. 2005 Nov 15; 65(22):10594-601.
    View in: PubMed
    Score: 0.046
  35. Estrogen receptor alpha-negative breast cancer tissues express significant levels of estrogen-independent transcription factors, ERbeta1 and ERbeta5: potential molecular targets for chemoprevention. Clin Cancer Res. 2005 Oct 15; 11(20):7579-85.
    View in: PubMed
    Score: 0.045
  36. Evidence that CRISPR-Cas9 Y537S-mutant expressing breast cancer cells activate Yes-associated protein 1 to driving the conversion of normal fibroblasts into cancer-associated fibroblasts. Cell Commun Signal. 2024 Nov 14; 22(1):545.
    View in: PubMed
    Score: 0.043
  37. Regulation of the estrogen receptor alpha minimal promoter by Sp1, USF-1 and ERalpha. Breast Cancer Res Treat. 2004 May; 85(2):111-20.
    View in: PubMed
    Score: 0.041
  38. Sp1 is essential for estrogen receptor alpha gene transcription. J Steroid Biochem Mol Biol. 2002 Sep; 82(1):7-18.
    View in: PubMed
    Score: 0.037
  39. A hypersensitive estrogen receptor-alpha mutation in premalignant breast lesions. Cancer Res. 2000 Aug 01; 60(15):4026-9.
    View in: PubMed
    Score: 0.032
  40. Leptin mediates tumor-stromal interactions that promote the invasive growth of breast cancer cells. Cancer Res. 2012 Mar 15; 72(6):1416-27.
    View in: PubMed
    Score: 0.018
  41. Dicer-mediated upregulation of BCRP confers tamoxifen resistance in human breast cancer cells. Clin Cancer Res. 2011 Oct 15; 17(20):6510-21.
    View in: PubMed
    Score: 0.017
  42. Resveratrol, through NF-Y/p53/Sin3/HDAC1 complex phosphorylation, inhibits estrogen receptor alpha gene expression via p38MAPK/CK2 signaling in human breast cancer cells. FASEB J. 2011 Oct; 25(10):3695-707.
    View in: PubMed
    Score: 0.017
  43. Direct acetylation of the estrogen receptor alpha hinge region by p300 regulates transactivation and hormone sensitivity. J Biol Chem. 2001 May 25; 276(21):18375-83.
    View in: PubMed
    Score: 0.008
Connection Strength

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Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.