OLIVIER LICHTARGE to Signal Transduction
This is a "connection" page, showing publications OLIVIER LICHTARGE has written about Signal Transduction.
Connection Strength
0.645
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Evolutionary traces of functional surfaces along G protein signaling pathway. Methods Enzymol. 2002; 344:536-56.
Score: 0.080
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A regulator of G protein signaling interaction surface linked to effector specificity. Proc Natl Acad Sci U S A. 2000 Feb 15; 97(4):1483-8.
Score: 0.070
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Residues and residue pairs of evolutionary importance differentially direct signaling bias of D2 dopamine receptors. J Biol Chem. 2019 12 13; 294(50):19279-19291.
Score: 0.069
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Exploring use of unsupervised clustering to associate signaling profiles of GPCR ligands to clinical response. Nat Commun. 2019 09 09; 10(1):4075.
Score: 0.068
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Type 2 diabetes-associated variants of the MT2 melatonin receptor affect distinct modes of signaling. Sci Signal. 2018 08 28; 11(545).
Score: 0.063
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Human muscle-specific A-kinase anchoring protein polymorphisms modulate the susceptibility to cardiovascular diseases by altering cAMP/PKA signaling. Am J Physiol Heart Circ Physiol. 2018 07 01; 315(1):H109-H121.
Score: 0.062
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Evolutionary action and structural basis of the allosteric switch controlling ?2AR functional selectivity. Nat Commun. 2017 12 18; 8(1):2169.
Score: 0.060
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Evolution-guided discovery and recoding of allosteric pathway specificity determinants in psychoactive bioamine receptors. Proc Natl Acad Sci U S A. 2010 Apr 27; 107(17):7787-92.
Score: 0.035
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Character and evolution of protein-protein interfaces. Phys Biol. 2005 Jun; 2(2):S36-43.
Score: 0.025
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Evolutionary trace of G protein-coupled receptors reveals clusters of residues that determine global and class-specific functions. J Biol Chem. 2004 Feb 27; 279(9):8126-32.
Score: 0.023
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Combinatorial inhibition of PTPN12-regulated receptors leads to a broadly effective therapeutic strategy in triple-negative breast cancer. Nat Med. 2018 05; 24(4):505-511.
Score: 0.015
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Determinants of endogenous ligand specificity divergence among metabotropic glutamate receptors. J Biol Chem. 2015 Jan 30; 290(5):2870-8.
Score: 0.012
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Selectivity and evolutionary divergence of metabotropic glutamate receptors for endogenous ligands and G proteins coupled to phospholipase C or TRP channels. J Biol Chem. 2014 Oct 24; 289(43):29961-74.
Score: 0.012
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The maternal-to-zygotic transition targets actin to promote robustness during morphogenesis. PLoS Genet. 2013 Nov; 9(11):e1003901.
Score: 0.011
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An angiotensin II type 1 receptor activation switch patch revealed through evolutionary trace analysis. Biochem Pharmacol. 2010 Jul 01; 80(1):86-94.
Score: 0.009
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Role for the regulator of G-protein signaling homology domain of G protein-coupled receptor kinases 5 and 6 in beta 2-adrenergic receptor and rhodopsin phosphorylation. Mol Pharmacol. 2010 Mar; 77(3):405-15.
Score: 0.009
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beta-arrestin-dependent, G protein-independent ERK1/2 activation by the beta2 adrenergic receptor. J Biol Chem. 2006 Jan 13; 281(2):1261-73.
Score: 0.007
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Conserved motifs in somatostatin, D2-dopamine, and alpha 2B-adrenergic receptors for inhibiting the Na-H exchanger, NHE1. J Biol Chem. 2003 Apr 25; 278(17):15128-35.
Score: 0.005
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Similar structures and shared switch mechanisms of the beta2-adrenoceptor and the parathyroid hormone receptor. Zn(II) bridges between helices III and VI block activation. J Biol Chem. 1999 Jun 11; 274(24):17033-41.
Score: 0.004
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C5a receptor activation. Genetic identification of critical residues in four transmembrane helices. J Biol Chem. 1999 May 28; 274(22):15757-65.
Score: 0.004