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MARGARET GOODELL to DNA (Cytosine-5-)-Methyltransferases

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This is a "connection" page, showing publications MARGARET GOODELL has written about DNA (Cytosine-5-)-Methyltransferases.
MARGARET GOODELL
Connection Strength
8.401
DNA (Cytosine-5-)-Methyltransferases
  1. DNMT3A-coordinated splicing governs the stem state switch towards differentiation in embryonic and haematopoietic stem cells. Nat Cell Biol. 2023 04; 25(4):528-539.
    View in: PubMed
    Score: 0.751
  2. Tissue-Biased Expansion of DNMT3A-Mutant Clones in a Mosaic Individual Is Associated with Conserved Epigenetic Erosion. Cell Stem Cell. 2020 08 06; 27(2):326-335.e4.
    View in: PubMed
    Score: 0.622
  3. Dnmt3a loss and Idh2 neomorphic mutations mutually potentiate malignant hematopoiesis. Blood. 2020 03 12; 135(11):845-856.
    View in: PubMed
    Score: 0.607
  4. DNMT3A and TET1 cooperate to regulate promoter epigenetic landscapes in mouse embryonic stem cells. Genome Biol. 2018 07 12; 19(1):88.
    View in: PubMed
    Score: 0.541
  5. DNA epigenome editing using CRISPR-Cas SunTag-directed DNMT3A. Genome Biol. 2017 09 18; 18(1):176.
    View in: PubMed
    Score: 0.511
  6. DNMT3A in Leukemia. Cold Spring Harb Perspect Med. 2017 Feb 01; 7(2).
    View in: PubMed
    Score: 0.489
  7. DNMT3A and TET2 compete and cooperate to repress lineage-specific transcription factors in hematopoietic stem cells. Nat Genet. 2016 09; 48(9):1014-23.
    View in: PubMed
    Score: 0.471
  8. DOT1L as a therapeutic target for the treatment of DNMT3A-mutant acute myeloid leukemia. Blood. 2016 08 18; 128(7):971-81.
    View in: PubMed
    Score: 0.469
  9. DNMT3A Loss Drives Enhancer Hypomethylation in FLT3-ITD-Associated Leukemias. Cancer Cell. 2016 06 13; 29(6):922-934.
    View in: PubMed
    Score: 0.468
  10. DNMT3A in haematological malignancies. Nat Rev Cancer. 2015 Mar; 15(3):152-65.
    View in: PubMed
    Score: 0.428
  11. Dnmt3a loss predisposes murine hematopoietic stem cells to malignant transformation. Blood. 2015 Jan 22; 125(4):629-38.
    View in: PubMed
    Score: 0.425
  12. Dnmt3a and Dnmt3b have overlapping and distinct functions in hematopoietic stem cells. Cell Stem Cell. 2014 Sep 04; 15(3):350-364.
    View in: PubMed
    Score: 0.412
  13. Dnmt3a is essential for hematopoietic stem cell differentiation. Nat Genet. 2011 Dec 04; 44(1):23-31.
    View in: PubMed
    Score: 0.342
  14. First-in-Class Allosteric Inhibitors of DNMT3A Disrupt Protein-Protein Interactions and Induce Acute Myeloid Leukemia Cell Differentiation. J Med Chem. 2022 08 11; 65(15):10554-10566.
    View in: PubMed
    Score: 0.179
  15. Constitutive loss of DNMT3A causes morbid obesity through misregulation of adipogenesis. Elife. 2022 05 30; 11.
    View in: PubMed
    Score: 0.177
  16. Perturbed hematopoiesis in individuals with germline DNMT3A overgrowth Tatton-Brown-Rahman syndrome. Haematologica. 2022 04 01; 107(4):887-898.
    View in: PubMed
    Score: 0.175
  17. Bcor deficiency perturbs erythro-megakaryopoiesis and cooperates with Dnmt3a loss in acute erythroid leukemia onset in mice. Leukemia. 2021 07; 35(7):1949-1963.
    View in: PubMed
    Score: 0.159
  18. Clonal hematopoiesis: mechanisms driving dominance of stem cell clones. Blood. 2020 10 01; 136(14):1590-1598.
    View in: PubMed
    Score: 0.158
  19. Losing Dnmt3a dependent methylation in inhibitory neurons impairs neural function by a mechanism impacting Rett syndrome. Elife. 2020 03 11; 9.
    View in: PubMed
    Score: 0.152
  20. Mutations in the DNMT3A DNA methyltransferase in acute myeloid leukemia patients cause both loss and gain of function and differential regulation by protein partners. J Biol Chem. 2019 03 29; 294(13):4898-4910.
    View in: PubMed
    Score: 0.141
  21. Loss of Dnmt3a Immortalizes Hematopoietic Stem Cells In?Vivo. Cell Rep. 2018 04 03; 23(1):1-10.
    View in: PubMed
    Score: 0.133
  22. Mixed-phenotype acute leukemia (MPAL) exhibits frequent mutations in DNMT3A and activated signaling genes. Exp Hematol. 2016 08; 44(8):740-4.
    View in: PubMed
    Score: 0.117
  23. Long non-coding RNAs control hematopoietic stem cell function. Cell Stem Cell. 2015 Apr 02; 16(4):426-38.
    View in: PubMed
    Score: 0.107
  24. New answers to old questions from genome-wide maps of DNA methylation in hematopoietic cells. Exp Hematol. 2014 Aug; 42(8):609-17.
    View in: PubMed
    Score: 0.102
  25. Large conserved domains of low DNA methylation maintained by Dnmt3a. Nat Genet. 2014 Jan; 46(1):17-23.
    View in: PubMed
    Score: 0.098
  26. A DNMT3A mutation common in AML exhibits dominant-negative effects in murine ES cells. Blood. 2013 Dec 12; 122(25):4086-9.
    View in: PubMed
    Score: 0.098
  27. Global DNA methylation remodeling during direct reprogramming of fibroblasts to neurons. Elife. 2019 01 15; 8.
    View in: PubMed
    Score: 0.035
  28. Homeobox oncogene activation by pan-cancer DNA hypermethylation. Genome Biol. 2018 08 10; 19(1):108.
    View in: PubMed
    Score: 0.034
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.