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TIMOTHY PALZKILL to beta-Lactamase Inhibitors

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This is a "connection" page, showing publications TIMOTHY PALZKILL has written about beta-Lactamase Inhibitors.
TIMOTHY PALZKILL
Connection Strength
7.820
beta-Lactamase Inhibitors
  1. Exploiting the Carboxylate-Binding Pocket of ?-Lactamase Enzymes Using a Focused DNA-Encoded Chemical Library. J Med Chem. 2024 01 11; 67(1):620-642.
    View in: PubMed
    Score: 0.819
  2. Deep Sequencing of a Systematic Peptide Library Reveals Conformationally-Constrained Protein Interface Peptides that Disrupt a Protein-Protein Interaction. Chembiochem. 2022 02 04; 23(3):e202100504.
    View in: PubMed
    Score: 0.711
  3. A drug-resistant ?-lactamase variant changes the conformation of its active-site proton shuttle to alter substrate specificity and inhibitor potency. J Biol Chem. 2020 12 25; 295(52):18239-18255.
    View in: PubMed
    Score: 0.659
  4. Identifying Oxacillinase-48 Carbapenemase Inhibitors Using DNA-Encoded Chemical Libraries. ACS Infect Dis. 2020 05 08; 6(5):1214-1227.
    View in: PubMed
    Score: 0.632
  5. Engineering Specificity from Broad to Narrow: Design of a ?-Lactamase Inhibitory Protein (BLIP) Variant That Exclusively Binds and Detects KPC ?-Lactamase. ACS Infect Dis. 2016 12 09; 2(12):969-979.
    View in: PubMed
    Score: 0.499
  6. Role of ?-lactamase residues in a common interface for binding the structurally unrelated inhibitory proteins BLIP and BLIP-II. Protein Sci. 2014 Sep; 23(9):1235-46.
    View in: PubMed
    Score: 0.425
  7. Identification of the ?-lactamase inhibitor protein-II (BLIP-II) interface residues essential for binding affinity and specificity for class A ?-lactamases. J Biol Chem. 2013 Jun 14; 288(24):17156-66.
    View in: PubMed
    Score: 0.392
  8. BLIP-II is a highly potent inhibitor of Klebsiella pneumoniae carbapenemase (KPC-2). Antimicrob Agents Chemother. 2013 Jul; 57(7):3398-401.
    View in: PubMed
    Score: 0.391
  9. Use of periplasmic target protein capture for phage display engineering of tight-binding protein-protein interactions. Protein Eng Des Sel. 2011 Nov; 24(11):819-28.
    View in: PubMed
    Score: 0.350
  10. Analysis of the binding forces driving the tight interactions between beta-lactamase inhibitory protein-II (BLIP-II) and class A beta-lactamases. J Biol Chem. 2011 Sep 16; 286(37):32723-35.
    View in: PubMed
    Score: 0.346
  11. Identification of a ?-lactamase inhibitory protein variant that is a potent inhibitor of Staphylococcus PC1 ?-lactamase. J Mol Biol. 2011 Mar 11; 406(5):730-44.
    View in: PubMed
    Score: 0.334
  12. Identification and characterization of beta-lactamase inhibitor protein-II (BLIP-II) interactions with beta-lactamases using phage display. Protein Eng Des Sel. 2010 Jun; 23(6):469-78.
    View in: PubMed
    Score: 0.316
  13. Fine mapping of the sequence requirements for binding of beta-lactamase inhibitory protein (BLIP) to TEM-1 beta-lactamase using a genetic screen for BLIP function. J Mol Biol. 2009 Jun 05; 389(2):401-12.
    View in: PubMed
    Score: 0.296
  14. A broad-spectrum peptide inhibitor of beta-lactamase identified using phage display and peptide arrays. Protein Eng. 2003 Nov; 16(11):853-60.
    View in: PubMed
    Score: 0.203
  15. Consensus on ?-Lactamase Nomenclature. Antimicrob Agents Chemother. 2022 04 19; 66(4):e0033322.
    View in: PubMed
    Score: 0.182
  16. Binding properties of a peptide derived from beta-lactamase inhibitory protein. Antimicrob Agents Chemother. 2001 Dec; 45(12):3279-86.
    View in: PubMed
    Score: 0.178
  17. Mapping Protein-Protein Interaction Interface Peptides with Jun-Fos Assisted Phage Display and Deep Sequencing. ACS Synth Biol. 2020 07 17; 9(7):1882-1896.
    View in: PubMed
    Score: 0.161
  18. Design of potent beta-lactamase inhibitors by phage display of beta-lactamase inhibitory protein. J Biol Chem. 2000 May 19; 275(20):14964-8.
    View in: PubMed
    Score: 0.160
  19. Development and Evaluation of a Novel Protein-Based Assay for Specific Detection of KPC ?-Lactamases from Klebsiella pneumoniae Clinical Isolates. mSphere. 2020 01 08; 5(1).
    View in: PubMed
    Score: 0.156
  20. Contributions of aspartate 49 and phenylalanine 142 residues of a tight binding inhibitory protein of beta-lactamases. J Biol Chem. 1999 Jan 22; 274(4):2394-400.
    View in: PubMed
    Score: 0.146
  21. Display of functional beta-lactamase inhibitory protein on the surface of M13 bacteriophage. Antimicrob Agents Chemother. 1998 Nov; 42(11):2893-7.
    View in: PubMed
    Score: 0.143
  22. 2-Substituted 4,5-dihydrothiazole-4-carboxylic acids are novel inhibitors of metallo-?-lactamases. Bioorg Med Chem Lett. 2012 Oct 01; 22(19):6229-32.
    View in: PubMed
    Score: 0.093
  23. Penicillin-derived inhibitors that simultaneously target both metallo- and serine-beta-lactamases. Bioorg Med Chem Lett. 2004 Mar 08; 14(5):1299-304.
    View in: PubMed
    Score: 0.052
  24. An analysis of why highly similar enzymes evolve differently. Genetics. 2003 Feb; 163(2):457-66.
    View in: PubMed
    Score: 0.048
  25. Protein minimization by random fragmentation and selection. Protein Eng. 2001 Jul; 14(7):487-92.
    View in: PubMed
    Score: 0.043
  26. A Standard Numbering Scheme for Class C ?-Lactamases. Antimicrob Agents Chemother. 2020 02 21; 64(3).
    View in: PubMed
    Score: 0.039
  27. Characterization of a PSE-4 mutant with different properties in relation to penicillanic acid sulfones: importance of residues 216 to 218 in class A beta-lactamases. Antimicrob Agents Chemother. 1998 Sep; 42(9):2319-25.
    View in: PubMed
    Score: 0.035
  28. Structure-function analysis of alpha-helix H4 using PSE-4 as a model enzyme representative of class A beta-lactamases. Protein Eng. 2000 Apr; 13(4):267-74.
    View in: PubMed
    Score: 0.010
Connection Strength

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Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.