Connection

TIMOTHY PALZKILL to Protein Structure, Tertiary

This is a "connection" page, showing publications TIMOTHY PALZKILL has written about Protein Structure, Tertiary.
Connection Strength

1.118
  1. Klebsiella pneumoniae carbapenemase variant 44 acquires ceftazidime-avibactam resistance by altering the conformation of active-site loops. J Biol Chem. 2024 01; 300(1):105493.
    View in: PubMed
    Score: 0.191
  2. Mutagenesis and structural analysis reveal the CTX-M ?-lactamase active site is optimized for cephalosporin catalysis and drug resistance. J Biol Chem. 2023 05; 299(5):104630.
    View in: PubMed
    Score: 0.182
  3. Systematic substitutions at BLIP position 50 result in changes in binding specificity for class A ?-lactamases. BMC Biochem. 2017 03 06; 18(1):2.
    View in: PubMed
    Score: 0.120
  4. A triple mutant in the O-loop of TEM-1 ?-lactamase changes the substrate profile via a large conformational change and an altered general base for catalysis. J Biol Chem. 2015 Apr 17; 290(16):10382-94.
    View in: PubMed
    Score: 0.104
  5. Evolution of antibiotic resistance: several different amino acid substitutions in an active site loop alter the substrate profile of beta-lactamase. Mol Microbiol. 1994 Apr; 12(2):217-29.
    View in: PubMed
    Score: 0.098
  6. Identification of a ?-lactamase inhibitory protein variant that is a potent inhibitor of Staphylococcus PC1 ?-lactamase. J Mol Biol. 2011 Mar 11; 406(5):730-44.
    View in: PubMed
    Score: 0.078
  7. Multiple global suppressors of protein stability defects facilitate the evolution of extended-spectrum TEM ?-lactamases. J Mol Biol. 2010 Dec 17; 404(5):832-46.
    View in: PubMed
    Score: 0.077
  8. Structural and biochemical evidence that a TEM-1 beta-lactamase N170G active site mutant acts via substrate-assisted catalysis. J Biol Chem. 2009 Nov 27; 284(48):33703-12.
    View in: PubMed
    Score: 0.072
  9. Dissecting the protein-protein interface between beta-lactamase inhibitory protein and class A beta-lactamases. J Biol Chem. 2004 Oct 08; 279(41):42860-6.
    View in: PubMed
    Score: 0.050
  10. Determinants of binding affinity and specificity for the interaction of TEM-1 and SME-1 beta-lactamase with beta-lactamase inhibitory protein. J Biol Chem. 2003 Nov 14; 278(46):45706-12.
    View in: PubMed
    Score: 0.047
  11. Identification of residues critical for metallo-beta-lactamase function by codon randomization and selection. Protein Sci. 2001 Dec; 10(12):2556-65.
    View in: PubMed
    Score: 0.042
  12. Crystallographic Analysis of Rotavirus NSP2-RNA Complex Reveals Specific Recognition of 5' GG Sequence for RTPase Activity. J Virol. 2012 Oct; 86(19):10547-57.
    View in: PubMed
    Score: 0.022
  13. Co-crystal structures of PKG I? (92-227) with cGMP and cAMP reveal the molecular details of cyclic-nucleotide binding. PLoS One. 2011 Apr 19; 6(4):e18413.
    View in: PubMed
    Score: 0.020
  14. Thermodynamic investigation of the role of contact residues of beta-lactamase-inhibitory protein for binding to TEM-1 beta-lactamase. J Biol Chem. 2007 Jun 15; 282(24):17676-84.
    View in: PubMed
    Score: 0.015
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.