Connection

HUI ZHENG to Mice

This is a "connection" page, showing publications HUI ZHENG has written about Mice.
Connection Strength

1.036
  1. TFEB-vacuolar ATPase signaling regulates lysosomal function and microglial activation in tauopathy. Nat Neurosci. 2024 Jan; 27(1):48-62.
    View in: PubMed
    Score: 0.054
  2. Oleoylethanolamide facilitates PPARa and TFEB signaling and attenuates A? pathology in a mouse model of Alzheimer's disease. Mol Neurodegener. 2023 08 15; 18(1):56.
    View in: PubMed
    Score: 0.053
  3. FoxO3 deficiency in cortical astrocytes leads to impaired lipid metabolism and aggravated amyloid pathology. Aging Cell. 2021 08; 20(8):e13432.
    View in: PubMed
    Score: 0.046
  4. An epoxide hydrolase inhibitor reduces neuroinflammation in a mouse model of Alzheimer's disease. Sci Transl Med. 2020 12 09; 12(573).
    View in: PubMed
    Score: 0.044
  5. TFEB regulates lysosomal exocytosis of tau and its loss of function exacerbates tau pathology and spreading. Mol Psychiatry. 2021 10; 26(10):5925-5939.
    View in: PubMed
    Score: 0.042
  6. Complement C3aR Inactivation Attenuates Tau Pathology and Reverses an Immune Network Deregulated in Tauopathy Models and Alzheimer's Disease. Neuron. 2018 12 19; 100(6):1337-1353.e5.
    View in: PubMed
    Score: 0.038
  7. The cargo receptor SQSTM1 ameliorates neurofibrillary tangle pathology and spreading through selective targeting of pathological MAPT (microtubule associated protein tau). Autophagy. 2019 04; 15(4):583-598.
    View in: PubMed
    Score: 0.038
  8. TFEB enhances astroglial uptake of extracellular tau species and reduces tau spreading. J Exp Med. 2018 09 03; 215(9):2355-2377.
    View in: PubMed
    Score: 0.037
  9. Practical considerations for choosing a mouse model of Alzheimer's disease. Mol Neurodegener. 2017 12 22; 12(1):89.
    View in: PubMed
    Score: 0.036
  10. Synaptic Adhesion Molecule Pcdh-?C5 Mediates Synaptic Dysfunction in Alzheimer's Disease. J Neurosci. 2017 09 20; 37(38):9259-9268.
    View in: PubMed
    Score: 0.035
  11. The Amyloid Precursor Protein Is a Conserved Receptor for Slit to Mediate Axon Guidance. eNeuro. 2017 May-Jun; 4(3).
    View in: PubMed
    Score: 0.034
  12. Posttraumatic stress disorder-like induction elevates ?-amyloid levels, which directly activates corticotropin-releasing factor neurons to exacerbate stress responses. J Neurosci. 2015 Feb 11; 35(6):2612-23.
    View in: PubMed
    Score: 0.029
  13. NF?B-activated astroglial release of complement C3 compromises neuronal morphology and function associated with Alzheimer's disease. Neuron. 2015 Jan 07; 85(1):101-115.
    View in: PubMed
    Score: 0.029
  14. The amyloid precursor protein controls adult hippocampal neurogenesis through GABAergic interneurons. J Neurosci. 2014 Oct 01; 34(40):13314-25.
    View in: PubMed
    Score: 0.029
  15. Modeling Alzheimer's disease in mouse without mutant protein overexpression: cooperative and independent effects of A? and tau. PLoS One. 2013; 8(11):e80706.
    View in: PubMed
    Score: 0.027
  16. I?Ba deficiency in brain leads to elevated basal neuroinflammation and attenuated response following traumatic brain injury: implications for functional recovery. Mol Neurodegener. 2012 Sep 19; 7:47.
    View in: PubMed
    Score: 0.025
  17. Amyloid precursor protein revisited: neuron-specific expression and highly stable nature of soluble derivatives. J Biol Chem. 2012 Jan 20; 287(4):2437-45.
    View in: PubMed
    Score: 0.023
  18. Transposon mutagenesis with coat color genotyping identifies an essential role for Skor2 in sonic hedgehog signaling and cerebellum development. Development. 2011 Oct; 138(20):4487-97.
    View in: PubMed
    Score: 0.023
  19. APP physiological and pathophysiological functions: insights from animal models. Cell Res. 2012 Jan; 22(1):78-89.
    View in: PubMed
    Score: 0.023
  20. Amyloid precursor protein regulates Cav1.2 L-type calcium channel levels and function to influence GABAergic short-term plasticity. J Neurosci. 2009 Dec 16; 29(50):15660-8.
    View in: PubMed
    Score: 0.020
  21. Presynaptic and postsynaptic interaction of the amyloid precursor protein promotes peripheral and central synaptogenesis. J Neurosci. 2009 Sep 02; 29(35):10788-801.
    View in: PubMed
    Score: 0.020
  22. Genetic dissection of gamma-secretase-dependent and -independent functions of presenilin in regulating neuronal cell cycle and cell death. J Neurosci. 2008 Oct 29; 28(44):11421-31.
    View in: PubMed
    Score: 0.019
  23. Increased asynchronous release and aberrant calcium channel activation in amyloid precursor protein deficient neuromuscular synapses. Neuroscience. 2007 Nov 23; 149(4):768-78.
    View in: PubMed
    Score: 0.017
  24. Deletion of presenilin 1 hydrophilic loop sequence leads to impaired gamma-secretase activity and exacerbated amyloid pathology. J Neurosci. 2006 Apr 05; 26(14):3845-54.
    View in: PubMed
    Score: 0.016
  25. Wild-type presenilin 1 protects against Alzheimer disease mutation-induced amyloid pathology. J Biol Chem. 2006 Jun 02; 281(22):15330-6.
    View in: PubMed
    Score: 0.016
  26. Regulation of tyrosinase trafficking and processing by presenilins: partial loss of function by familial Alzheimer's disease mutation. Proc Natl Acad Sci U S A. 2006 Jan 10; 103(2):353-8.
    View in: PubMed
    Score: 0.016
  27. Defective neuromuscular synapses in mice lacking amyloid precursor protein (APP) and APP-Like protein 2. J Neurosci. 2005 Feb 02; 25(5):1219-25.
    View in: PubMed
    Score: 0.015
  28. Myeloproliferative disease in mice with reduced presenilin gene dosage: effect of gamma-secretase blockage. Biochemistry. 2004 May 11; 43(18):5352-9.
    View in: PubMed
    Score: 0.014
  29. Presenilin 1 familial Alzheimer's disease mutation leads to defective associative learning and impaired adult neurogenesis. Neuroscience. 2004; 126(2):305-12.
    View in: PubMed
    Score: 0.014
  30. Toll-like receptor 4 and CD11b expressed on microglia coordinate eradication of Candida albicans cerebral mycosis. Cell Rep. 2023 10 31; 42(10):113240.
    View in: PubMed
    Score: 0.013
  31. Presenilins are required for the formation of comma- and S-shaped bodies during nephrogenesis. Development. 2003 Oct; 130(20):5019-29.
    View in: PubMed
    Score: 0.013
  32. Droplet-based transcriptome profiling of individual synapses. Nat Biotechnol. 2023 09; 41(9):1332-1344.
    View in: PubMed
    Score: 0.013
  33. Concerted type I interferon signaling in microglia and neural cells promotes memory impairment associated with amyloid ? plaques. Immunity. 2022 05 10; 55(5):879-894.e6.
    View in: PubMed
    Score: 0.012
  34. Accelerated plaque accumulation, associative learning deficits, and up-regulation of alpha 7 nicotinic receptor protein in transgenic mice co-expressing mutant human presenilin 1 and amyloid precursor proteins. J Biol Chem. 2002 Jun 21; 277(25):22768-80.
    View in: PubMed
    Score: 0.012
  35. RNA-Seq Reveals Sub-Zones in Mouse Adrenal Zona Fasciculata and the Sexually Dimorphic Responses to Thyroid Hormone. Endocrinology. 2020 09 01; 161(9).
    View in: PubMed
    Score: 0.011
  36. Meta-Analysis of the Alzheimer's Disease Human Brain Transcriptome and Functional Dissection in Mouse Models. Cell Rep. 2020 07 14; 32(2):107908.
    View in: PubMed
    Score: 0.011
  37. Microwaving and Fluorophore-Tyramide for Multiplex Immunostaining on Mouse Adrenals - Using Unconjugated Primary Antibodies from the Same Host Species. J Vis Exp. 2020 02 21; (156).
    View in: PubMed
    Score: 0.010
  38. Microglia and amyloid precursor protein coordinate control of transient Candida cerebritis with memory deficits. Nat Commun. 2019 01 04; 10(1):58.
    View in: PubMed
    Score: 0.010
  39. Neuronal Deletion of Ghrelin Receptor Almost Completely Prevents Diet-Induced Obesity. Diabetes. 2016 08; 65(8):2169-78.
    View in: PubMed
    Score: 0.008
  40. Genetic suppression of transgenic APP rescues Hypersynchronous network activity in a mouse model of Alzeimer's disease. J Neurosci. 2014 Mar 12; 34(11):3826-40.
    View in: PubMed
    Score: 0.007
  41. Central CRF system perturbation in an Alzheimer's disease knockin mouse model. Neurobiol Aging. 2012 Nov; 33(11):2678-91.
    View in: PubMed
    Score: 0.006
  42. The intracellular threonine of amyloid precursor protein that is essential for docking of Pin1 is dispensable for developmental function. PLoS One. 2011 Mar 22; 6(3):e18006.
    View in: PubMed
    Score: 0.006
  43. A single tyrosine residue in the amyloid precursor protein intracellular domain is essential for developmental function. J Biol Chem. 2011 Mar 18; 286(11):8717-21.
    View in: PubMed
    Score: 0.006
  44. Convergence of presenilin- and tau-mediated pathways on axonal trafficking and neuronal function. J Neurosci. 2010 Oct 06; 30(40):13409-18.
    View in: PubMed
    Score: 0.005
  45. Soluble amyloid precursor protein (APP) regulates transthyretin and Klotho gene expression without rescuing the essential function of APP. Proc Natl Acad Sci U S A. 2010 Oct 05; 107(40):17362-7.
    View in: PubMed
    Score: 0.005
  46. Defective feedback regulation of NF-kappaB underlies Sjogren's syndrome in mice with mutated kappaB enhancers of the IkappaBalpha promoter. Proc Natl Acad Sci U S A. 2010 Aug 24; 107(34):15193-8.
    View in: PubMed
    Score: 0.005
  47. Genetic dissection of the amyloid precursor protein in developmental function and amyloid pathogenesis. J Biol Chem. 2010 Oct 01; 285(40):30598-605.
    View in: PubMed
    Score: 0.005
  48. Regulation of cholesterol efflux by amyloid beta secretion. J Neurosci Res. 2010 Jul; 88(9):1985-94.
    View in: PubMed
    Score: 0.005
  49. Loss of alpha7 nicotinic receptors enhances beta-amyloid oligomer accumulation, exacerbating early-stage cognitive decline and septohippocampal pathology in a mouse model of Alzheimer's disease. J Neurosci. 2010 Feb 17; 30(7):2442-53.
    View in: PubMed
    Score: 0.005
  50. Pen2 and presenilin-1 modulate the dynamic equilibrium of presenilin-1 and presenilin-2 gamma-secretase complexes. J Biol Chem. 2009 Jan 30; 284(5):2967-2977.
    View in: PubMed
    Score: 0.005
  51. Dimorphic effects of Notch signaling in bone homeostasis. Nat Med. 2008 Mar; 14(3):299-305.
    View in: PubMed
    Score: 0.005
  52. Presenilin 1 regulates epidermal growth factor receptor turnover and signaling in the endosomal-lysosomal pathway. J Biol Chem. 2007 Oct 26; 282(43):31504-16.
    View in: PubMed
    Score: 0.004
  53. In vivo axonal transport rates decrease in a mouse model of Alzheimer's disease. Neuroimage. 2007 May 01; 35(4):1401-8.
    View in: PubMed
    Score: 0.004
  54. Phospholipase D1 corrects impaired betaAPP trafficking and neurite outgrowth in familial Alzheimer's disease-linked presenilin-1 mutant neurons. Proc Natl Acad Sci U S A. 2006 Feb 07; 103(6):1936-40.
    View in: PubMed
    Score: 0.004
  55. Suppression of cyclin-dependent kinase 5 activation by amyloid precursor protein: a novel excitoprotective mechanism involving modulation of tau phosphorylation. J Neurosci. 2005 Dec 14; 25(50):11542-52.
    View in: PubMed
    Score: 0.004
  56. Presenilin 1 mediates the turnover of telencephalin in hippocampal neurons via an autophagic degradative pathway. J Cell Biol. 2004 Sep 27; 166(7):1041-54.
    View in: PubMed
    Score: 0.004
  57. Ghrelin stimulation of growth hormone release and appetite is mediated through the growth hormone secretagogue receptor. Proc Natl Acad Sci U S A. 2004 Mar 30; 101(13):4679-84.
    View in: PubMed
    Score: 0.003
  58. Presenilin-1 regulates intracellular trafficking and cell surface delivery of beta-amyloid precursor protein. J Biol Chem. 2003 Jan 31; 278(5):3446-54.
    View in: PubMed
    Score: 0.003
  59. Impairment in hippocampal long-term potentiation in mice under-expressing the Alzheimer's disease related gene presenilin-1. Neurosci Lett. 2002 Feb 08; 319(1):37-40.
    View in: PubMed
    Score: 0.003
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.