MARIA BOTTAZZI to Necator americanus
This is a "connection" page, showing publications MARIA BOTTAZZI has written about Necator americanus.
Connection Strength
3.461
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Expression, purification, and characterization of the Necator americanus aspartic protease-1 (Na-APR-1 (M74)) antigen, a component of the bivalent human hookworm vaccine. Hum Vaccin Immunother. 2015; 11(6):1474-88.
Score: 0.418
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Fusion of Na-ASP-2 with human immunoglobulin Fc? abrogates histamine release from basophils sensitized with anti-Na-ASP-2 IgE. Parasite Immunol. 2012 Aug-Sep; 34(8-9):404-11.
Score: 0.353
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Expression, purification, and molecular analysis of the Necator americanus glutathione S-transferase 1 (Na-GST-1): a production process developed for a lead candidate recombinant hookworm vaccine antigen. Protein Expr Purif. 2012 Jun; 83(2):145-51.
Score: 0.345
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Na-GST-1 adsorbed on Alhydrogel co-administered with different Toll-like receptor agonists in hookworm-naive adults using a controlled human infection model in the USA: a phase 2, double-blind, randomised controlled trial. Lancet Infect Dis. 2026 07; 26(7):692-704.
Score: 0.227
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Proteomic characterization and comparison of the infective and adult life stage secretomes from Necator americanus and Ancylostoma ceylanicum. PLoS Negl Trop Dis. 2025 Jan; 19(1):e0012780.
Score: 0.210
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Altering the intracellular trafficking of Necator americanus GST-1 antigen yields novel hookworm mRNA vaccine candidates. PLoS Negl Trop Dis. 2025 Jan; 19(1):e0012809.
Score: 0.209
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Randomized, observer-blind, controlled Phase 1 study of the safety and immunogenicity of the Na-GST-1/Alhydrogel hookworm vaccine with or without a CpG ODN adjuvant in hookworm-na?ve adults. PLoS Negl Trop Dis. 2024 12; 18(12):e0012788.
Score: 0.209
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Safety and immunogenicity of the co-administered Na-APR-1 and Na-GST-1 hookworm vaccines in school-aged children in Gabon: a randomised, controlled, observer-blind, phase 1, dose-escalation trial. Lancet Infect Dis. 2024 07; 24(7):760-774.
Score: 0.198
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Optimization and revision of the production process of the Necator americanus glutathione S-transferase 1 (Na-GST-1), the lead hookworm vaccine recombinant protein candidate. Hum Vaccin Immunother. 2014; 10(7):1914-25.
Score: 0.195
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Controlled Infection of Humans with the Hookworm Parasite Necator americanus to Accelerate Vaccine Development : The Human Hookworm Vaccination/Challenge Model (HVCM). Curr Top Microbiol Immunol. 2024; 445:367-377.
Score: 0.195
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Safety and immunogenicity of co-administered hookworm vaccine candidates Na-GST-1 and Na-APR-1 in Gabonese adults: a randomised, controlled, double-blind, phase 1 dose-escalation trial. Lancet Infect Dis. 2021 02; 21(2):275-285.
Score: 0.155
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A novel blood-feeding detoxification pathway in Nippostrongylus brasiliensis L3 reveals a potential checkpoint for arresting hookworm development. PLoS Pathog. 2018 03; 14(3):e1006931.
Score: 0.131
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Advancing a vaccine to prevent hookworm disease and anemia. Vaccine. 2016 06 03; 34(26):3001-3005.
Score: 0.114
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Advances in vaccines against neglected tropical diseases: enhancing physical stability of a recombinant hookworm vaccine through biophysical and formulation studies. Hum Vaccin Immunother. 2012 Jun; 8(6):765-76.
Score: 0.086
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Potency testing for the experimental Na-GST-1 hookworm vaccine. Expert Rev Vaccines. 2010 Oct; 9(10):1219-30.
Score: 0.078
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Molecular cloning, biochemical characterization, and partial protective immunity of the heme-binding glutathione S-transferases from the human hookworm Necator americanus. Infect Immun. 2010 Apr; 78(4):1552-63.
Score: 0.074
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An enzymatically inactivated hemoglobinase from Necator americanus induces neutralizing antibodies against multiple hookworm species and protects dogs against heterologous hookworm infection. FASEB J. 2009 Sep; 23(9):3007-19.
Score: 0.070
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Expression of the Necator americanus hookworm larval antigen Na-ASP-2 in Pichia pastoris and purification of the recombinant protein for use in human clinical trials. Vaccine. 2005 Sep 15; 23(39):4754-64.
Score: 0.055
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Antibodies against a secreted protein from hookworm larvae reduce the intensity of hookworm infection in humans and vaccinated laboratory animals. FASEB J. 2005 Oct; 19(12):1743-5.
Score: 0.054
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Immunogenicity of the hookworm Na-ASP-2 vaccine candidate: characterization of humoral and cellular responses after vaccination in the Sprague Dawley rat. Hum Vaccin. 2005 May-Jun; 1(3):123-8.
Score: 0.054
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Human Intestinal Parasite Burden and Poor Sanitation in Rural Alabama. Am J Trop Med Hyg. 2017 Nov; 97(5):1623-1628.
Score: 0.032