KE-HE RUAN to Prostaglandin-E Synthases
This is a "connection" page, showing publications KE-HE RUAN has written about Prostaglandin-E Synthases.
Connection Strength
1.375
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Identification of the two-phase mechanism of arachidonic acid regulating inflammatory prostaglandin E2 biosynthesis by targeting COX-2 and mPGES-1. Arch Biochem Biophys. 2016 08 01; 603:29-37.
Score: 0.531
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Latest advancements in the study of the relationship between NSAIDs and three prostaglandin E2 synthases. Future Med Chem. 2023 09; 15(17):1549-1552.
Score: 0.221
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Design, synthesis and characterization of lead compounds as anti-inflammatory drugs targeting mPGES-1 via enzymelink screening. Future Med Chem. 2023 05; 15(9):757-767.
Score: 0.217
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Latest progress in the development of cyclooxygenase-2 pathway inhibitors targeting microsomal prostaglandin E2 synthase-1. Future Med Chem. 2022 03; 14(6):385-388.
Score: 0.197
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Relationship of the Topological Distances and Activities between mPGES-1 and COX-2 versus COX-1: Implications of the Different Post-Translational Endoplasmic Reticulum Organizations of COX-1 and COX-2. Biochemistry. 2015 Jun 16; 54(23):3707-15.
Score: 0.125
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Engineering of a novel hybrid enzyme: an anti-inflammatory drug target with triple catalytic activities directly converting arachidonic acid into the inflammatory prostaglandin E2. Protein Eng Des Sel. 2009 Dec; 22(12):733-40.
Score: 0.084