KE-HE RUAN to Mutagenesis, Site-Directed
This is a "connection" page, showing publications KE-HE RUAN has written about Mutagenesis, Site-Directed.
Connection Strength
0.509
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The key residue within the second extracellular loop of human EP3 involved in selectively turning down PGE2- and retaining PGE1-mediated signaling in live cells. Arch Biochem Biophys. 2017 02 15; 616:20-29.
Score: 0.131
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Identification of the two-phase mechanism of arachidonic acid regulating inflammatory prostaglandin E2 biosynthesis by targeting COX-2 and mPGES-1. Arch Biochem Biophys. 2016 08 01; 603:29-37.
Score: 0.126
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Involvement of non-conserved residues important for PGE2 binding to the constrained EP3 eLP2 using NMR and site-directed mutagenesis. FEBS Lett. 2008 Aug 20; 582(19):2863-8.
Score: 0.073
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A profile of the residues in the second extracellular loop that are critical for ligand recognition of human prostacyclin receptor. FEBS J. 2008 Jan; 275(1):128-37.
Score: 0.070
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Identification of the residues in the helix F/G loop important to catalytic function of membrane-bound prostacyclin synthase. Biochemistry. 2003 May 20; 42(19):5609-17.
Score: 0.051
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Identification of residues important for ligand binding of thromboxane A2 receptor in the second extracellular loop using the NMR experiment-guided mutagenesis approach. J Biol Chem. 2003 Mar 28; 278(13):10922-7.
Score: 0.050
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Role of Val509 in time-dependent inhibition of human prostaglandin H synthase-2 cyclooxygenase activity by isoform-selective agents. J Biol Chem. 1996 Aug 09; 271(32):19134-9.
Score: 0.008