Connection

MING HU to Rats

This is a "connection" page, showing publications MING HU has written about Rats.
Connection Strength

1.515
  1. Rapid intestinal glucuronidation and hepatic glucuronide recycling contributes significantly to the enterohepatic circulation of icaritin and its glucuronides in vivo. Arch Toxicol. 2020 11; 94(11):3737-3749.
    View in: PubMed
    Score: 0.105
  2. Accurate quantification of PGE2 in the polyposis in rat colon (Pirc) model by surrogate analyte-based UPLC-MS/MS. J Pharm Biomed Anal. 2018 Jan 30; 148:42-50.
    View in: PubMed
    Score: 0.085
  3. Development and validation of an UPLC-MS/MS method for the quantification of irinotecan, SN-38 and SN-38 glucuronide in plasma, urine, feces, liver and kidney: Application to a pharmacokinetic study of irinotecan in rats. J Chromatogr B Analyt Technol Biomed Life Sci. 2016 Mar 15; 1015-1016:34-41.
    View in: PubMed
    Score: 0.077
  4. Factors Influencing Oral Bioavailability of Thai Mango Seed Kernel Extract and Its Key Phenolic Principles. Molecules. 2015 Nov 30; 20(12):21254-73.
    View in: PubMed
    Score: 0.076
  5. Development and validation of an UPLC-MS/MS method for the quantification of columbin in biological matrices: Applications to absorption, metabolism, and pharmacokinetic studies. J Chromatogr B Analyt Technol Biomed Life Sci. 2015 Oct 01; 1002:13-8.
    View in: PubMed
    Score: 0.074
  6. Quantitation of celecoxib and four of its metabolites in rat blood by UPLC-MS/MS clarifies their blood distribution patterns and provides more accurate pharmacokinetics profiles. J Chromatogr B Analyt Technol Biomed Life Sci. 2015 Sep 15; 1001:202-11.
    View in: PubMed
    Score: 0.074
  7. Effects of estrogen and estrus cycle on pharmacokinetics, absorption, and disposition of genistein in female Sprague-Dawley rats. J Agric Food Chem. 2012 Aug 15; 60(32):7949-56.
    View in: PubMed
    Score: 0.060
  8. Role of intestinal hydrolase in the absorption of prenylated flavonoids present in Yinyanghuo. Molecules. 2011 Feb 01; 16(2):1336-48.
    View in: PubMed
    Score: 0.054
  9. The pharmacokinetics of raloxifene and its interaction with apigenin in rat. Molecules. 2010 Nov 18; 15(11):8478-87.
    View in: PubMed
    Score: 0.053
  10. Breast cancer resistance protein (BCRP) and sulfotransferases contribute significantly to the disposition of genistein in mouse intestine. AAPS J. 2010 Dec; 12(4):525-36.
    View in: PubMed
    Score: 0.052
  11. Bioavailability challenges associated with development of anti-cancer phenolics. Mini Rev Med Chem. 2010 Jun; 10(6):550-67.
    View in: PubMed
    Score: 0.052
  12. Biopharmaceutical and pharmacokinetic characterization of matrine as determined by a sensitive and robust UPLC-MS/MS method. J Pharm Biomed Anal. 2010 Apr 06; 51(5):1120-7.
    View in: PubMed
    Score: 0.050
  13. Disposition of naringenin via glucuronidation pathway is affected by compensating efflux transporters of hydrophilic glucuronides. Mol Pharm. 2009 Nov-Dec; 6(6):1703-15.
    View in: PubMed
    Score: 0.050
  14. Disposition of flavonoids via enteric recycling: UDP-glucuronosyltransferase (UGT) 1As deficiency in Gunn rats is compensated by increases in UGT2Bs activities. J Pharmacol Exp Ther. 2009 Jun; 329(3):1023-31.
    View in: PubMed
    Score: 0.047
  15. Intestinal absorption mechanisms of prenylated flavonoids present in the heat-processed Epimedium koreanum Nakai (Yin Yanghuo). Pharm Res. 2008 Sep; 25(9):2190-9.
    View in: PubMed
    Score: 0.045
  16. Disposition of flavonoids via enteric recycling: enzyme stability affects characterization of prunetin glucuronidation across species, organs, and UGT isoforms. Mol Pharm. 2007 Nov-Dec; 4(6):883-94.
    View in: PubMed
    Score: 0.043
  17. Mechanisms responsible for poor oral bioavailability of paeoniflorin: Role of intestinal disposition and interactions with sinomenine. Pharm Res. 2006 Dec; 23(12):2768-80.
    View in: PubMed
    Score: 0.040
  18. Disposition of flavonoids via enteric recycling: structural effects and lack of correlations between in vitro and in situ metabolic properties. Drug Metab Dispos. 2006 Nov; 34(11):1837-48.
    View in: PubMed
    Score: 0.040
  19. Disposition of flavonoids via recycling: comparison of intestinal versus hepatic disposition. Drug Metab Dispos. 2005 Dec; 33(12):1777-84.
    View in: PubMed
    Score: 0.037
  20. Species- and disposition model-dependent metabolism of raloxifene in gut and liver: role of UGT1A10. Drug Metab Dispos. 2005 Jun; 33(6):785-94.
    View in: PubMed
    Score: 0.036
  21. Disposition of flavonoids via enteric recycling: enzyme-transporter coupling affects metabolism of biochanin A and formononetin and excretion of their phase II conjugates. J Pharmacol Exp Ther. 2004 Sep; 310(3):1103-13.
    View in: PubMed
    Score: 0.034
  22. Enteric disposition and recycling of flavonoids and ginkgo flavonoids. J Altern Complement Med. 2003 Oct; 9(5):631-40.
    View in: PubMed
    Score: 0.033
  23. Functional and molecular characterization of rat intestinal prolidase. Pediatr Res. 2003 Jun; 53(6):905-14.
    View in: PubMed
    Score: 0.031
  24. Metabolism of flavonoids via enteric recycling: role of intestinal disposition. J Pharmacol Exp Ther. 2003 Mar; 304(3):1228-35.
    View in: PubMed
    Score: 0.031
  25. Absorption and metabolism of flavonoids in the caco-2 cell culture model and a perused rat intestinal model. Drug Metab Dispos. 2002 Apr; 30(4):370-7.
    View in: PubMed
    Score: 0.029
  26. Age-and Region-Dependent Disposition of Raloxifene in Rats. Pharm Res. 2021 Aug; 38(8):1357-1367.
    View in: PubMed
    Score: 0.028
  27. Determination of absorption characteristics of AG337, a novel thymidylate synthase inhibitor, using a perfused rat intestinal model. J Pharm Sci. 1998 Jul; 87(7):886-90.
    View in: PubMed
    Score: 0.023
  28. Comparison of the transport characteristics of D- and L-methionine in a human intestinal epithelial model (Caco-2) and in a perfused rat intestinal model. Pharm Res. 1994 Dec; 11(12):1771-6.
    View in: PubMed
    Score: 0.018
  29. A novel local recycling mechanism that enhances enteric bioavailability of flavonoids and prolongs their residence time in the gut. Mol Pharm. 2012 Nov 05; 9(11):3246-58.
    View in: PubMed
    Score: 0.015
  30. Pharmacokinetics and renal disposition of polymyxin B in an animal model. Antimicrob Agents Chemother. 2012 Nov; 56(11):5724-7.
    View in: PubMed
    Score: 0.015
  31. Characterization of polymyxin B-induced nephrotoxicity: implications for dosing regimen design. Antimicrob Agents Chemother. 2012 Sep; 56(9):4625-9.
    View in: PubMed
    Score: 0.015
  32. Development and validation of a highly sensitive UPLC-MS/MS method for simultaneous determination of aconitine, mesaconitine, hypaconitine, and five of their metabolites in rat blood and its application to a pharmacokinetics study of aconitine, mesaconitine, and hypaconitine. Xenobiotica. 2012 Jun; 42(6):518-25.
    View in: PubMed
    Score: 0.014
  33. Sulfation of selected mono-hydroxyflavones by sulfotransferases in vitro: a species and gender comparison. J Pharm Pharmacol. 2011 Jul; 63(7):967-70.
    View in: PubMed
    Score: 0.014
  34. Poor oral bioavailability of a promising anticancer agent andrographolide is due to extensive metabolism and efflux by P-glycoprotein. J Pharm Sci. 2011 Nov; 100(11):5007-17.
    View in: PubMed
    Score: 0.014
  35. Sensitive and robust UPLC-MS/MS method to determine the gender-dependent pharmacokinetics in rats of emodin and its glucuronide. J Pharm Biomed Anal. 2011 Apr 05; 54(5):1157-62.
    View in: PubMed
    Score: 0.013
  36. Passive and carrier-mediated intestinal absorption components of captopril. J Pharm Sci. 1988 Dec; 77(12):1007-11.
    View in: PubMed
    Score: 0.012
  37. In vivo pharmacokinetics of hesperidin are affected by treatment with glucosidase-like BglA protein isolated from yeasts. J Agric Food Chem. 2008 Jul 23; 56(14):5550-7.
    View in: PubMed
    Score: 0.011
  38. Membrane permeability parameters for some amino acids and beta-lactam antibiotics: application of the boundary layer approach. J Theor Biol. 1988 Mar 07; 131(1):107-14.
    View in: PubMed
    Score: 0.011
  39. Utilization of peptide carrier system to improve intestinal absorption: targeting prolidase as a prodrug-converting enzyme. J Pharm Sci. 1992 Feb; 81(2):113-6.
    View in: PubMed
    Score: 0.004
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.