Connection

MING HU to Animals

This is a "connection" page, showing publications MING HU has written about Animals.
Connection Strength

0.542
  1. Bioavailability and pharmacokinetics of genistein: mechanistic studies on its ADME. Anticancer Agents Med Chem. 2012 Dec; 12(10):1264-80.
    View in: PubMed
    Score: 0.019
  2. Effects of estrogen and estrus cycle on pharmacokinetics, absorption, and disposition of genistein in female Sprague-Dawley rats. J Agric Food Chem. 2012 Aug 15; 60(32):7949-56.
    View in: PubMed
    Score: 0.019
  3. Breast cancer resistance protein (ABCG2) determines distribution of genistein phase II metabolites: reevaluation of the roles of ABCG2 in the disposition of genistein. Drug Metab Dispos. 2012 Oct; 40(10):1883-93.
    View in: PubMed
    Score: 0.019
  4. Inhibition of P-glycoprotein leads to improved oral bioavailability of compound K, an anticancer metabolite of red ginseng extract produced by gut microflora. Drug Metab Dispos. 2012 Aug; 40(8):1538-44.
    View in: PubMed
    Score: 0.019
  5. Substrate selectivity of drug-metabolizing cytochrome P450s predicted from crystal structures and in silico modeling. Drug Metab Rev. 2012 May; 44(2):192-208.
    View in: PubMed
    Score: 0.018
  6. Regioselective sulfation and glucuronidation of phenolics: insights into the structural basis. Curr Drug Metab. 2011 Nov; 12(9):900-16.
    View in: PubMed
    Score: 0.018
  7. Enhancement of oral bioavailability of 20(S)-ginsenoside Rh2 through improved understanding of its absorption and efflux mechanisms. Drug Metab Dispos. 2011 Oct; 39(10):1866-72.
    View in: PubMed
    Score: 0.017
  8. First-pass metabolism via UDP-glucuronosyltransferase: a barrier to oral bioavailability of phenolics. J Pharm Sci. 2011 Sep; 100(9):3655-81.
    View in: PubMed
    Score: 0.017
  9. Role of intestinal hydrolase in the absorption of prenylated flavonoids present in Yinyanghuo. Molecules. 2011 Feb 01; 16(2):1336-48.
    View in: PubMed
    Score: 0.017
  10. Validated LC-MS/MS method for the determination of maackiain and its sulfate and glucuronide in blood: application to pharmacokinetic and disposition studies. J Pharm Biomed Anal. 2011 May 15; 55(2):288-93.
    View in: PubMed
    Score: 0.017
  11. The pharmacokinetics of raloxifene and its interaction with apigenin in rat. Molecules. 2010 Nov 18; 15(11):8478-87.
    View in: PubMed
    Score: 0.017
  12. Breast cancer resistance protein (BCRP) and sulfotransferases contribute significantly to the disposition of genistein in mouse intestine. AAPS J. 2010 Dec; 12(4):525-36.
    View in: PubMed
    Score: 0.016
  13. Bioavailability challenges associated with development of anti-cancer phenolics. Mini Rev Med Chem. 2010 Jun; 10(6):550-67.
    View in: PubMed
    Score: 0.016
  14. Simultaneous determination of genistein and its four phase II metabolites in blood by a sensitive and robust UPLC-MS/MS method: Application to an oral bioavailability study of genistein in mice. J Pharm Biomed Anal. 2010 Sep 21; 53(1):81-9.
    View in: PubMed
    Score: 0.016
  15. Biopharmaceutical and pharmacokinetic characterization of matrine as determined by a sensitive and robust UPLC-MS/MS method. J Pharm Biomed Anal. 2010 Apr 06; 51(5):1120-7.
    View in: PubMed
    Score: 0.016
  16. Disposition of naringenin via glucuronidation pathway is affected by compensating efflux transporters of hydrophilic glucuronides. Mol Pharm. 2009 Nov-Dec; 6(6):1703-15.
    View in: PubMed
    Score: 0.016
  17. Disposition of flavonoids via enteric recycling: UDP-glucuronosyltransferase (UGT) 1As deficiency in Gunn rats is compensated by increases in UGT2Bs activities. J Pharmacol Exp Ther. 2009 Jun; 329(3):1023-31.
    View in: PubMed
    Score: 0.015
  18. Intestinal absorption mechanisms of prenylated flavonoids present in the heat-processed Epimedium koreanum Nakai (Yin Yanghuo). Pharm Res. 2008 Sep; 25(9):2190-9.
    View in: PubMed
    Score: 0.014
  19. Commentary: bioavailability of flavonoids and polyphenols: call to arms. Mol Pharm. 2007 Nov-Dec; 4(6):803-6.
    View in: PubMed
    Score: 0.014
  20. Disposition of flavonoids via enteric recycling: enzyme stability affects characterization of prunetin glucuronidation across species, organs, and UGT isoforms. Mol Pharm. 2007 Nov-Dec; 4(6):883-94.
    View in: PubMed
    Score: 0.014
  21. Natural polyphenol disposition via coupled metabolic pathways. Expert Opin Drug Metab Toxicol. 2007 Jun; 3(3):389-406.
    View in: PubMed
    Score: 0.013
  22. Mechanisms responsible for poor oral bioavailability of paeoniflorin: Role of intestinal disposition and interactions with sinomenine. Pharm Res. 2006 Dec; 23(12):2768-80.
    View in: PubMed
    Score: 0.013
  23. Disposition of flavonoids via enteric recycling: structural effects and lack of correlations between in vitro and in situ metabolic properties. Drug Metab Dispos. 2006 Nov; 34(11):1837-48.
    View in: PubMed
    Score: 0.012
  24. Disposition of flavonoids via recycling: comparison of intestinal versus hepatic disposition. Drug Metab Dispos. 2005 Dec; 33(12):1777-84.
    View in: PubMed
    Score: 0.012
  25. Disposition of formononetin via enteric recycling: metabolism and excretion in mouse intestinal perfusion and Caco-2 cell models. Mol Pharm. 2005 Jul-Aug; 2(4):319-28.
    View in: PubMed
    Score: 0.012
  26. Species- and disposition model-dependent metabolism of raloxifene in gut and liver: role of UGT1A10. Drug Metab Dispos. 2005 Jun; 33(6):785-94.
    View in: PubMed
    Score: 0.011
  27. Disposition of flavonoids via enteric recycling: enzyme-transporter coupling affects metabolism of biochanin A and formononetin and excretion of their phase II conjugates. J Pharmacol Exp Ther. 2004 Sep; 310(3):1103-13.
    View in: PubMed
    Score: 0.011
  28. Enteric disposition and recycling of flavonoids and ginkgo flavonoids. J Altern Complement Med. 2003 Oct; 9(5):631-40.
    View in: PubMed
    Score: 0.010
  29. Functional and molecular characterization of rat intestinal prolidase. Pediatr Res. 2003 Jun; 53(6):905-14.
    View in: PubMed
    Score: 0.010
  30. Metabolism of flavonoids via enteric recycling: role of intestinal disposition. J Pharmacol Exp Ther. 2003 Mar; 304(3):1228-35.
    View in: PubMed
    Score: 0.010
  31. Absorption and metabolism of flavonoids in the caco-2 cell culture model and a perused rat intestinal model. Drug Metab Dispos. 2002 Apr; 30(4):370-7.
    View in: PubMed
    Score: 0.009
  32. P-glycoprotein and bioavailability-implication of polymorphism. Clin Chem Lab Med. 2000 Sep; 38(9):877-81.
    View in: PubMed
    Score: 0.008
  33. Determination of absorption characteristics of AG337, a novel thymidylate synthase inhibitor, using a perfused rat intestinal model. J Pharm Sci. 1998 Jul; 87(7):886-90.
    View in: PubMed
    Score: 0.007
  34. Comparison of the transport characteristics of D- and L-methionine in a human intestinal epithelial model (Caco-2) and in a perfused rat intestinal model. Pharm Res. 1994 Dec; 11(12):1771-6.
    View in: PubMed
    Score: 0.006
  35. A novel local recycling mechanism that enhances enteric bioavailability of flavonoids and prolongs their residence time in the gut. Mol Pharm. 2012 Nov 05; 9(11):3246-58.
    View in: PubMed
    Score: 0.005
  36. Pharmacokinetics and renal disposition of polymyxin B in an animal model. Antimicrob Agents Chemother. 2012 Nov; 56(11):5724-7.
    View in: PubMed
    Score: 0.005
  37. CYP3A-dependent drug metabolism is reduced in bacterial inflammation in mice. Br J Pharmacol. 2012 Aug; 166(7):2176-87.
    View in: PubMed
    Score: 0.005
  38. Characterization of polymyxin B-induced nephrotoxicity: implications for dosing regimen design. Antimicrob Agents Chemother. 2012 Sep; 56(9):4625-9.
    View in: PubMed
    Score: 0.005
  39. Systematic studies of sulfation and glucuronidation of 12 flavonoids in the mouse liver S9 fraction reveal both unique and shared positional preferences. J Agric Food Chem. 2012 Mar 28; 60(12):3223-33.
    View in: PubMed
    Score: 0.005
  40. Development and validation of a highly sensitive UPLC-MS/MS method for simultaneous determination of aconitine, mesaconitine, hypaconitine, and five of their metabolites in rat blood and its application to a pharmacokinetics study of aconitine, mesaconitine, and hypaconitine. Xenobiotica. 2012 Jun; 42(6):518-25.
    View in: PubMed
    Score: 0.005
  41. Chemopreventive effect of a mixture of Chinese Herbs (antitumor B) on chemically induced oral carcinogenesis. Mol Carcinog. 2013 Jan; 52(1):49-56.
    View in: PubMed
    Score: 0.004
  42. Sulfation of selected mono-hydroxyflavones by sulfotransferases in vitro: a species and gender comparison. J Pharm Pharmacol. 2011 Jul; 63(7):967-70.
    View in: PubMed
    Score: 0.004
  43. Poor oral bioavailability of a promising anticancer agent andrographolide is due to extensive metabolism and efflux by P-glycoprotein. J Pharm Sci. 2011 Nov; 100(11):5007-17.
    View in: PubMed
    Score: 0.004
  44. Sensitive and robust UPLC-MS/MS method to determine the gender-dependent pharmacokinetics in rats of emodin and its glucuronide. J Pharm Biomed Anal. 2011 Apr 05; 54(5):1157-62.
    View in: PubMed
    Score: 0.004
  45. Species and gender differences affect the metabolism of emodin via glucuronidation. AAPS J. 2010 Sep; 12(3):424-36.
    View in: PubMed
    Score: 0.004
  46. Use of the peptide carrier system to improve the intestinal absorption of L-alpha-methyldopa: carrier kinetics, intestinal permeabilities, and in vitro hydrolysis of dipeptidyl derivatives of L-alpha-methyldopa. Pharm Res. 1989 Jan; 6(1):66-70.
    View in: PubMed
    Score: 0.004
  47. Passive and carrier-mediated intestinal absorption components of captopril. J Pharm Sci. 1988 Dec; 77(12):1007-11.
    View in: PubMed
    Score: 0.004
  48. In vivo pharmacokinetics of hesperidin are affected by treatment with glucosidase-like BglA protein isolated from yeasts. J Agric Food Chem. 2008 Jul 23; 56(14):5550-7.
    View in: PubMed
    Score: 0.004
  49. Membrane permeability parameters for some amino acids and beta-lactam antibiotics: application of the boundary layer approach. J Theor Biol. 1988 Mar 07; 131(1):107-14.
    View in: PubMed
    Score: 0.003
  50. Analysis of drug transport and metabolism in cell monolayer systems that have been modified by cytochrome P4503A4 cDNA-expression. Eur J Pharm Sci. 2000 Nov; 12(1):63-8.
    View in: PubMed
    Score: 0.002
  51. Utilization of peptide carrier system to improve intestinal absorption: targeting prolidase as a prodrug-converting enzyme. J Pharm Sci. 1992 Feb; 81(2):113-6.
    View in: PubMed
    Score: 0.001
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.