Header Logo

Connection

BHAGAVATULA MOORTHY to Cytochrome P-450 CYP1A1

Back to Details
This is a "connection" page, showing publications BHAGAVATULA MOORTHY has written about Cytochrome P-450 CYP1A1.
BHAGAVATULA MOORTHY
Connection Strength
7.640
Cytochrome P-450 CYP1A1
  1. Role of Cytochrome P450 (CYP)1A in Hyperoxic Lung Injury: Analysis of the Transcriptome and Proteome. Sci Rep. 2017 04 04; 7(1):642.
    View in: PubMed
    Score: 0.538
  2. Sex-specific differences in hyperoxic lung injury in mice: role of cytochrome P450 (CYP)1A. Toxicology. 2015 May 04; 331:14-23.
    View in: PubMed
    Score: 0.465
  3. Mice deficient in the gene for cytochrome P450 (CYP)1A1 are more susceptible than wild-type to hyperoxic lung injury: evidence for protective role of CYP1A1 against oxidative stress. Toxicol Sci. 2014 Sep; 141(1):68-77.
    View in: PubMed
    Score: 0.442
  4. Prenatal administration of the cytochrome P4501A inducer, ?-naphthoflavone (BNF), attenuates hyperoxic lung injury in newborn mice: implications for bronchopulmonary dysplasia (BPD) in premature infants. Toxicol Appl Pharmacol. 2011 Oct 15; 256(2):83-94.
    View in: PubMed
    Score: 0.361
  5. Augmented oxygen-mediated transcriptional activation of cytochrome P450 (CYP)1A expression and increased susceptibilities to hyperoxic lung injury in transgenic mice carrying the human CYP1A1 or mouse 1A2 promoter in vivo. Biochem Biophys Res Commun. 2011 Apr 01; 407(1):79-85.
    View in: PubMed
    Score: 0.353
  6. Disruption of the gene for CYP1A2, which is expressed primarily in liver, leads to differential regulation of hepatic and pulmonary mouse CYP1A1 expression and augmented human CYP1A1 transcriptional activation in response to 3-methylcholanthrene in vivo. J Pharmacol Exp Ther. 2010 Nov; 335(2):369-79.
    View in: PubMed
    Score: 0.340
  7. Persistent induction of cytochrome P4501A1 in human hepatoma cells by 3-methylcholanthrene: evidence for sustained transcriptional activation of the CYP1A1 promoter. J Pharmacol Exp Ther. 2010 Apr; 333(1):99-109.
    View in: PubMed
    Score: 0.326
  8. Persistent induction of cytochrome P450 (CYP)1A enzymes by 3-methylcholanthrene in vivo in mice is mediated by sustained transcriptional activation of the corresponding promoters. Biochem Biophys Res Commun. 2009 Dec 25; 390(4):1419-24.
    View in: PubMed
    Score: 0.322
  9. Regulation of cytochrome P4501A1 expression by hyperoxia in human lung cell lines: Implications for hyperoxic lung injury. Toxicol Appl Pharmacol. 2008 Dec 01; 233(2):169-78.
    View in: PubMed
    Score: 0.297
  10. 3-Methylcholanthrene elicits DNA adduct formation in the CYP1A1 promoter region and attenuates reporter gene expression in rat H4IIE cells. Biochem Biophys Res Commun. 2007 Mar 23; 354(4):1071-7.
    View in: PubMed
    Score: 0.266
  11. Modulation of pulmonary cytochrome P4501A1 expression by hyperoxia and inhaled nitric oxide in the newborn rat: implications for lung injury. Pediatr Res. 2006 Mar; 59(3):401-6.
    View in: PubMed
    Score: 0.250
  12. Attenuation of oxygen-induced abnormal lung maturation in rats by retinoic acid: possible role of cytochrome P4501A enzymes. J Pharmacol Exp Ther. 2006 Jun; 317(3):946-54.
    View in: PubMed
    Score: 0.249
  13. Attenuation of hyperoxic lung injury by the CYP1A inducer beta-naphthoflavone. Toxicol Sci. 2005 Sep; 87(1):204-12.
    View in: PubMed
    Score: 0.238
  14. Disruption of the Ah receptor gene alters the susceptibility of mice to oxygen-mediated regulation of pulmonary and hepatic cytochromes P4501A expression and exacerbates hyperoxic lung injury. J Pharmacol Exp Ther. 2004 Aug; 310(2):512-9.
    View in: PubMed
    Score: 0.220
  15. Prenatal exposure to polycyclic aromatic hydrocarbons (PAHs) augments neonatal hyperoxic lung injury: Role of cytochrome P450 (CYP)1A1, 1A2, and 1B1. Free Radic Biol Med. 2024 02 01; 211:35-46.
    View in: PubMed
    Score: 0.214
  16. Loss of cytochrome P450 (CYP)1B1 mitigates hyperoxia response in adult mouse lung by reprogramming metabolism and translation. Redox Biol. 2023 08; 64:102790.
    View in: PubMed
    Score: 0.207
  17. Polycyclic aromatic hydrocarbon-inducible DNA adducts: evidence by 32P-postlabeling and use of knockout mice for Ah receptor-independent mechanisms of metabolic activation in vivo. Int J Cancer. 2003 Jan 01; 103(1):5-11.
    View in: PubMed
    Score: 0.200
  18. Differential regulation of expression of hepatic and pulmonary cytochrome P4501A enzymes by 3-methylcholanthrene in mice lacking the CYP1A2 gene. J Pharmacol Exp Ther. 2002 Dec; 303(3):945-51.
    View in: PubMed
    Score: 0.199
  19. Regulation of pulmonary and hepatic cytochrome P4501A expression in the rat by hyperoxia: implications for hyperoxic lung injury. Mol Pharmacol. 2002 Mar; 61(3):507-15.
    View in: PubMed
    Score: 0.189
  20. 3-Methylcholanthrene-inducible hepatic DNA adducts: a mechanistic hypothesis linking sequence-specific DNA adducts to sustained cytochrome P4501A1 induction by 3-methylcholanthrene. Redox Rep. 2002; 7(1):9-13.
    View in: PubMed
    Score: 0.187
  21. Polycyclic Aromatic Hydrocarbon-induced Pulmonary Carcinogenesis in Cytochrome P450 (CYP)1A1- and 1A2-Null Mice: Roles of CYP1A1 and CYP1A2. Toxicol Sci. 2020 10 01; 177(2):347-361.
    View in: PubMed
    Score: 0.171
  22. Oxygen-mediated lung injury in mice lacking the gene for NRF2: Rescue with the cytochrome P4501A-inducer, beta-naphthoflavone (BNF), and differential sex-specific effects. Free Radic Biol Med. 2020 11 20; 160:208-218.
    View in: PubMed
    Score: 0.170
  23. Persistent expression of 3-methylcholanthrene-inducible cytochromes P4501A in rat hepatic and extrahepatic tissues. J Pharmacol Exp Ther. 2000 Jul; 294(1):313-22.
    View in: PubMed
    Score: 0.169
  24. Newborn Mice Lacking the Gene for Cyp1a1 Are More Susceptible to Oxygen-Mediated Lung Injury, and Are Rescued by Postnatal ?-Naphthoflavone Administration: Implications for Bronchopulmonary Dysplasia in Premature Infants. Toxicol Sci. 2017 05 01; 157(1):260-271.
    View in: PubMed
    Score: 0.135
  25. Leflunomide induces NAD(P)H quinone dehydrogenase 1 enzyme via the aryl hydrocarbon receptor in neonatal mice. Biochem Biophys Res Commun. 2017 03 25; 485(1):195-200.
    View in: PubMed
    Score: 0.133
  26. Induction and decline of hepatic cytochromes P4501A1 and 1A2 in rats exposed to hyperoxia are not paralleled by changes in glutathione S-transferase-alpha. Toxicol Lett. 1997 Jan 15; 90(1):67-75.
    View in: PubMed
    Score: 0.133
  27. Sex-specific differences in neonatal hyperoxic lung injury. Am J Physiol Lung Cell Mol Physiol. 2016 Aug 01; 311(2):L481-93.
    View in: PubMed
    Score: 0.128
  28. Leflunomide Induces Pulmonary and Hepatic CYP1A Enzymes via Aryl Hydrocarbon Receptor. Drug Metab Dispos. 2015 Dec; 43(12):1966-70.
    View in: PubMed
    Score: 0.121
  29. Role of mammary epithelial and stromal P450 enzymes in the clearance and metabolic activation of 7,12-dimethylbenz(a)anthracene in mice. Toxicol Lett. 2012 Jul 20; 212(2):97-105.
    View in: PubMed
    Score: 0.096
  30. Role of retinoic acid in the modulation of benzo(a)pyrene-DNA adducts in human hepatoma cells: implications for cancer prevention. Toxicol Appl Pharmacol. 2010 Dec 15; 249(3):224-30.
    View in: PubMed
    Score: 0.086
  31. An alternatively spliced cytochrome P4501A1 in human brain fails to bioactivate polycyclic aromatic hydrocarbons to DNA-reactive metabolites. J Neurochem. 2007 Aug; 102(3):867-77.
    View in: PubMed
    Score: 0.069
  32. Effects of 3-methylcholanthrene on gene expression profiling in the rat using cDNA microarray analyses. Chem Res Toxicol. 2005 Nov; 18(11):1634-41.
    View in: PubMed
    Score: 0.061
  33. Induction of CYP1A1 and CYP1B1 in liver and lung by benzo(a)pyrene and 7,12-d imethylbenz(a)anthracene do not affect distribution of polycyclic hydrocarbons to target tissue: role of AhR and CYP1B1 in bone marrow cytotoxicity. Toxicol Appl Pharmacol. 2005 Feb 01; 202(3):244-57.
    View in: PubMed
    Score: 0.058
  34. Cytochrome P450 1A1 is essential for the microbial metabolite, Urolithin A-mediated protection against colitis. Front Immunol. 2022; 13:1004603.
    View in: PubMed
    Score: 0.049
  35. Potentiation of oxygen-induced lung injury in rats by the mechanism-based cytochrome P-450 inhibitor, 1-aminobenzotriazole. J Pharmacol Exp Ther. 2000 Feb; 292(2):553-60.
    View in: PubMed
    Score: 0.041
  36. Pentachlorophenol enhances 9-hydroxybenzo [a] pyrene-induced hepatic DNA adduct formation in vivo and inhibits microsomal epoxide hydrolase and glutathione S-transferase activities in vitro: likely inhibition of epoxide detoxication by pentachlorophenol. Arch Toxicol. 1996; 70(11):696-703.
    View in: PubMed
    Score: 0.031
  37. Effects of a single dose of the cytochrome P450 inducer, beta-naphthoflavone, on hepatic and renal covalent DNA modifications (I-compounds). Toxicology. 1995 Dec 15; 104(1-3):165-77.
    View in: PubMed
    Score: 0.031
  38. Omeprazole induces NAD(P)H quinone oxidoreductase 1 via aryl hydrocarbon receptor-independent mechanisms: Role of the transcription factor nuclear factor erythroid 2-related factor 2. Biochem Biophys Res Commun. 2015 Nov 13; 467(2):282-7.
    View in: PubMed
    Score: 0.030
  39. Increased susceptibility to hyperoxic lung injury and alveolar simplification in newborn rats by prenatal administration of benzo[a]pyrene. Toxicol Lett. 2014 Oct 15; 230(2):322-32.
    View in: PubMed
    Score: 0.027
  40. 3-Methylcholanthrene-inducible liver cytochrome(s) P450 in female Sprague-Dawley rats: possible link between P450 turnover and formation of DNA adducts and I-compounds. Carcinogenesis. 1993 May; 14(5):879-86.
    View in: PubMed
    Score: 0.026
  41. Characterization of a major aromatic DNA adduct detected in human breast tissues. Environ Mol Mutagen. 2002; 39(2-3):193-200.
    View in: PubMed
    Score: 0.012
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.