LAWRENCE DONEHOWER to Signal Transduction
This is a "connection" page, showing publications LAWRENCE DONEHOWER has written about Signal Transduction.
Connection Strength
0.761
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The type 2C phosphatase Wip1: an oncogenic regulator of tumor suppressor and DNA damage response pathways. Cancer Metastasis Rev. 2008 Jun; 27(2):123-35.
Score: 0.128
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The Wip1 Phosphatase acts as a gatekeeper in the p53-Mdm2 autoregulatory loop. Cancer Cell. 2007 Oct; 12(4):342-54.
Score: 0.122
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PPM1D dephosphorylates Chk1 and p53 and abrogates cell cycle checkpoints. Genes Dev. 2005 May 15; 19(10):1162-74.
Score: 0.104
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Enhanced inflammation and attenuated tumor suppressor pathways are associated with oncogene-induced lung tumors in aged mice. Aging Cell. 2018 02; 17(1).
Score: 0.061
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Effects of TP53 mutational status on gene expression patterns across 10 human cancer types. J Pathol. 2014 Apr; 232(5):522-33.
Score: 0.047
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Mouse tissues that undergo neoplastic progression after K-Ras activation are distinguished by nuclear translocation of phospho-Erk1/2 and robust tumor suppressor responses. Mol Cancer Res. 2012 Jun; 10(6):845-55.
Score: 0.042
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Mdm2-p53 signaling regulates epidermal stem cell senescence and premature aging phenotypes in mouse skin. Dev Biol. 2011 May 01; 353(1):1-9.
Score: 0.039
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Disrupting circadian homeostasis of sympathetic signaling promotes tumor development in mice. PLoS One. 2010 Jun 07; 5(6):e10995.
Score: 0.037
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Notch signaling contributes to the pathogenesis of human osteosarcomas. Hum Mol Genet. 2009 Apr 15; 18(8):1464-70.
Score: 0.034
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Longevity regulation in flies: a role for p53. Aging (Albany NY). 2009 Jan 10; 1(1):6-8.
Score: 0.033
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How does suppression of IGF-1 signaling by DNA damage affect aging and longevity? Mech Ageing Dev. 2008 May; 129(5):243-53.
Score: 0.031
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Reversal of the ATM/ATR-mediated DNA damage response by the oncogenic phosphatase PPM1D. Cell Cycle. 2005 Aug; 4(8):1060-4.
Score: 0.026
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miR-130b directly targets ARHGAP1 to drive activation of a metastatic CDC42-PAK1-AP1 positive feedback loop in Ewing sarcoma. Int J Cancer. 2017 11 15; 141(10):2062-2075.
Score: 0.015
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Genomic profiling of S?zary syndrome identifies alterations of key T cell signaling and differentiation genes. Nat Genet. 2015 Dec; 47(12):1426-34.
Score: 0.013
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The tumor suppressor p53. Biochim Biophys Acta. 1993 Aug 23; 1155(2):181-205.
Score: 0.012
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Rpl27a mutation in the sooty foot ataxia mouse phenocopies high p53 mouse models. J Pathol. 2011 Aug; 224(4):540-52.
Score: 0.010
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The integrin-linked kinase regulates the cyclin D1 gene through glycogen synthase kinase 3beta and cAMP-responsive element-binding protein-dependent pathways. J Biol Chem. 2000 Oct 20; 275(42):32649-57.
Score: 0.005