Connection

ORLA CONNEELY to Animals

This is a "connection" page, showing publications ORLA CONNEELY has written about Animals.
Connection Strength

0.619
  1. Targeting Oncogenic Super Enhancers in MYC-Dependent AML Using a Small Molecule Activator of NR4A Nuclear Receptors. Sci Rep. 2020 02 18; 10(1):2851.
    View in: PubMed
    Score: 0.032
  2. Drug targeting of NR4A nuclear receptors for treatment of acute myeloid leukemia. Leukemia. 2019 01; 33(1):52-63.
    View in: PubMed
    Score: 0.028
  3. Reprogramming of the estrogen responsive transcriptome contributes to tamoxifen-dependent protection against tumorigenesis in the p53 null mammary epithelial cells. PLoS One. 2018; 13(3):e0194913.
    View in: PubMed
    Score: 0.028
  4. NR4A1 and NR4A3 restrict HSC proliferation via reciprocal regulation of C/EBPa and inflammatory signaling. Blood. 2018 03 08; 131(10):1081-1093.
    View in: PubMed
    Score: 0.027
  5. Research resource: progesterone receptor targetome underlying mammary gland branching morphogenesis. Mol Endocrinol. 2013 Oct; 27(10):1743-61.
    View in: PubMed
    Score: 0.020
  6. Reduced NR4A gene dosage leads to mixed myelodysplastic/myeloproliferative neoplasms in mice. Blood. 2011 Mar 03; 117(9):2681-90.
    View in: PubMed
    Score: 0.017
  7. Progesterone receptors and ovulation. Handb Exp Pharmacol. 2010; (198):37-44.
    View in: PubMed
    Score: 0.016
  8. Stimulus-dependent impairment of the neutrophil oxidative burst response in lactoferrin-deficient mice. Am J Pathol. 2008 Apr; 172(4):1019-29.
    View in: PubMed
    Score: 0.014
  9. Abrogation of nuclear receptors Nr4a3 and Nr4a1 leads to development of acute myeloid leukemia. Nat Med. 2007 Jun; 13(6):730-5.
    View in: PubMed
    Score: 0.013
  10. Progestins and the mammary gland. From basic science to clinical applications. Preface. Ernst Schering Found Symp Proc. 2007; (1):V-VII.
    View in: PubMed
    Score: 0.013
  11. Progesterone signaling in mammary gland development. Ernst Schering Found Symp Proc. 2007; (1):45-54.
    View in: PubMed
    Score: 0.013
  12. Differential response of progesterone receptor isoforms in hormone-dependent and -independent facilitation of female sexual receptivity. Mol Endocrinol. 2006 Jun; 20(6):1322-32.
    View in: PubMed
    Score: 0.012
  13. Multifunctional roles of lactoferrin: a critical overview. Cell Mol Life Sci. 2005 Nov; 62(22):2540-8.
    View in: PubMed
    Score: 0.012
  14. Reproductive tissue-selective actions of progesterone receptors. Ernst Schering Res Found Workshop. 2005; (52):19-37.
    View in: PubMed
    Score: 0.011
  15. nor-1 regulates hippocampal axon guidance, pyramidal cell survival, and seizure susceptibility. Mol Cell Biol. 2004 Oct; 24(20):9070-8.
    View in: PubMed
    Score: 0.011
  16. Reproductive tissue selective actions of progesterone receptors. Reproduction. 2004 Aug; 128(2):139-46.
    View in: PubMed
    Score: 0.011
  17. Progesterone-dependent regulation of female reproductive activity by two distinct progesterone receptor isoforms. Steroids. 2003 Nov; 68(10-13):771-8.
    View in: PubMed
    Score: 0.010
  18. Defective mammary gland morphogenesis in mice lacking the progesterone receptor B isoform. Proc Natl Acad Sci U S A. 2003 Aug 19; 100(17):9744-9.
    View in: PubMed
    Score: 0.010
  19. Progesterone receptors in mammary gland development and tumorigenesis. J Mammary Gland Biol Neoplasia. 2003 Apr; 8(2):205-14.
    View in: PubMed
    Score: 0.010
  20. Iron status in mice carrying a targeted disruption of lactoferrin. Mol Cell Biol. 2003 Jan; 23(1):178-85.
    View in: PubMed
    Score: 0.010
  21. The nuclear receptor Nor-1 is essential for proliferation of the semicircular canals of the mouse inner ear. Mol Cell Biol. 2002 Feb; 22(3):935-45.
    View in: PubMed
    Score: 0.009
  22. Lactoferrin and host defense. Biochem Cell Biol. 2002; 80(1):95-102.
    View in: PubMed
    Score: 0.009
  23. Reproductive functions of progesterone receptors. Recent Prog Horm Res. 2002; 57:339-55.
    View in: PubMed
    Score: 0.009
  24. Antiinflammatory activities of lactoferrin. J Am Coll Nutr. 2001 Oct; 20(5 Suppl):389S-395S; discussion 396S-397S.
    View in: PubMed
    Score: 0.009
  25. Reproductive functions of the progesterone receptor isoforms: lessons from knock-out mice. Mol Cell Endocrinol. 2001 Jun 20; 179(1-2):97-103.
    View in: PubMed
    Score: 0.009
  26. Perspective: female steroid hormone action. Endocrinology. 2001 Jun; 142(6):2194-9.
    View in: PubMed
    Score: 0.009
  27. Progesterone receptors in reproduction: functional impact of the A and B isoforms. Steroids. 2000 Oct-Nov; 65(10-11):571-7.
    View in: PubMed
    Score: 0.008
  28. Subgroup of reproductive functions of progesterone mediated by progesterone receptor-B isoform. Science. 2000 Sep 08; 289(5485):1751-4.
    View in: PubMed
    Score: 0.008
  29. A reappraisal of progesterone action in the mammary gland. J Mammary Gland Biol Neoplasia. 2000 Jul; 5(3):325-38.
    View in: PubMed
    Score: 0.008
  30. Reproductive functions of the progesterone receptor. J Soc Gynecol Investig. 2000 Jan-Feb; 7(1 Suppl):S25-32.
    View in: PubMed
    Score: 0.008
  31. Restricted spatiotemporal expression of lactoferrin during murine embryonic development. Endocrinology. 1999 Apr; 140(4):1852-60.
    View in: PubMed
    Score: 0.007
  32. Mutual and intercompartmental regulation of estrogen receptor and progesterone receptor expression in the mouse uterus. Biol Reprod. 1998 Nov; 59(5):1143-52.
    View in: PubMed
    Score: 0.007
  33. Nurr1 is essential for the induction of the dopaminergic phenotype and the survival of ventral mesencephalic late dopaminergic precursor neurons. Proc Natl Acad Sci U S A. 1998 Mar 31; 95(7):4013-8.
    View in: PubMed
    Score: 0.007
  34. Restricted spatiotemporal expression of lactoferrin during murine embryogenesis. Adv Exp Med Biol. 1998; 443:91-100.
    View in: PubMed
    Score: 0.007
  35. Regulation by lactoferrin of epidermal Langerhans cell migration. Adv Exp Med Biol. 1998; 443:251-5.
    View in: PubMed
    Score: 0.007
  36. Expression and characterization of recombinant murine lactoferrin. Gene. 1997 Dec 19; 204(1-2):171-6.
    View in: PubMed
    Score: 0.007
  37. Cloning and structural organization of the gene encoding the murine nuclear receptor transcription factor, NURR1. Gene. 1997 Mar 10; 187(1):135-9.
    View in: PubMed
    Score: 0.006
  38. Neuroendocrine regulation of the hypothalamic pituitary adrenal axis by the nurr1/nur77 subfamily of nuclear receptors. Mol Endocrinol. 1997 Jan; 11(1):39-47.
    View in: PubMed
    Score: 0.006
  39. Commercial production of lactoferrin, a multifunctional iron-binding glycoprotein. Biotechnol Genet Eng Rev. 1997; 14:303-19.
    View in: PubMed
    Score: 0.006
  40. Comparative distribution of NURR1 and NUR77 nuclear receptors in the mouse central nervous system. J Mol Neurosci. 1996; 7(1):51-63.
    View in: PubMed
    Score: 0.006
  41. A system for production of commercial quantities of human lactoferrin: a broad spectrum natural antibiotic. Biotechnology (N Y). 1995 May; 13(5):498-503.
    View in: PubMed
    Score: 0.006
  42. The orphan nuclear receptor Nur77 is a determinant of myofiber size and muscle mass in mice. Mol Cell Biol. 2015 Apr; 35(7):1125-38.
    View in: PubMed
    Score: 0.006
  43. Nuclear receptor 4a3 (nr4a3) regulates murine mast cell responses and granule content. PLoS One. 2014; 9(2):e89311.
    View in: PubMed
    Score: 0.005
  44. Bone marrow NR4A expression is not a dominant factor in the development of atherosclerosis or macrophage polarization in mice. J Lipid Res. 2013 Mar; 54(3):806-815.
    View in: PubMed
    Score: 0.005
  45. Structural organization of the mouse lactoferrin gene. Biochem Biophys Res Commun. 1992 Dec 30; 189(3):1725-31.
    View in: PubMed
    Score: 0.005
  46. Orphan receptors: in search of a unifying hypothesis for activation. Mol Endocrinol. 1992 Sep; 6(9):1359-61.
    View in: PubMed
    Score: 0.005
  47. Nucleotide and primary amino acid sequence of porcine lactoferrin. Biochim Biophys Acta. 1992 Aug 17; 1132(1):97-9.
    View in: PubMed
    Score: 0.005
  48. A novel, highly regulated, rapidly inducible system for the expression of chicken progesterone receptor, cPRA, in Saccharomyces cerevisiae. Gene. 1992 May 01; 114(1):51-8.
    View in: PubMed
    Score: 0.005
  49. Regulation of gene expression by dopamine: implications in drug addiction. NIDA Res Monogr. 1992; 126:84-97.
    View in: PubMed
    Score: 0.005
  50. The orphan nuclear receptor Nurr1 restricts the proliferation of haematopoietic stem cells. Nat Cell Biol. 2010 Dec; 12(12):1213-9.
    View in: PubMed
    Score: 0.004
  51. Deficiency of the NR4A orphan nuclear receptor NOR1 decreases monocyte adhesion and atherosclerosis. Circ Res. 2010 Aug 20; 107(4):501-11.
    View in: PubMed
    Score: 0.004
  52. The chicken progesterone receptor A and B isoforms are products of an alternate translation initiation event. J Biol Chem. 1989 Aug 25; 264(24):14062-4.
    View in: PubMed
    Score: 0.004
  53. Deficiency of the NR4A neuron-derived orphan receptor-1 attenuates neointima formation after vascular injury. Circulation. 2009 Feb 03; 119(4):577-86.
    View in: PubMed
    Score: 0.004
  54. Structure-function relationships of the chicken progesterone receptor. Biochem Soc Trans. 1988 Oct; 16(5):683-7.
    View in: PubMed
    Score: 0.004
  55. The A and B forms of the chicken progesterone receptor arise by alternate initiation of translation of a unique mRNA. Biochem Biophys Res Commun. 1987 Dec 16; 149(2):493-501.
    View in: PubMed
    Score: 0.003
  56. Ataxia telangiectasia-mutated and p53 are potential mediators of chloroquine-induced resistance to mammary carcinogenesis. Cancer Res. 2007 Dec 15; 67(24):12026-33.
    View in: PubMed
    Score: 0.003
  57. Sequence and expression of a functional chicken progesterone receptor. Mol Endocrinol. 1987 Aug; 1(8):517-25.
    View in: PubMed
    Score: 0.003
  58. Overlapping and distinct expression of progesterone receptors A and B in mouse uterus and mammary gland during the estrous cycle. Endocrinology. 2006 Dec; 147(12):5503-12.
    View in: PubMed
    Score: 0.003
  59. The NR4A orphan nuclear receptor NOR1 is induced by platelet-derived growth factor and mediates vascular smooth muscle cell proliferation. J Biol Chem. 2006 Nov 03; 281(44):33467-76.
    View in: PubMed
    Score: 0.003
  60. Molecular cloning of the chicken progesterone receptor. Science. 1986 Aug 15; 233(4765):767-70.
    View in: PubMed
    Score: 0.003
  61. Progesterone receptor isoforms A and B differentially regulate MUC1 expression in uterine epithelial cells. Mol Endocrinol. 2006 Oct; 20(10):2278-91.
    View in: PubMed
    Score: 0.003
  62. Nitric oxide mediates increased susceptibility to dopaminergic damage in Nurr1 heterozygous mice. FASEB J. 2005 Sep; 19(11):1441-50.
    View in: PubMed
    Score: 0.003
  63. Revealing progesterone's role in uterine and mammary gland biology: insights from the mouse. Semin Reprod Med. 2005 Feb; 23(1):22-37.
    View in: PubMed
    Score: 0.003
  64. Progesterone involvement in breast development and tumorigenesis--as revealed by progesterone receptor "knockout" and "knockin" mouse models. Steroids. 2003 Nov; 68(10-13):779-87.
    View in: PubMed
    Score: 0.003
  65. Involvement of Nurr1 in specifying the neurotransmitter identity of ventral midbrain dopaminergic neurons. Eur J Neurosci. 2003 Oct; 18(7):1731-8.
    View in: PubMed
    Score: 0.003
  66. Progesterone's role in mammary gland development and tumorigenesis as disclosed by experimental mouse genetics. Breast Cancer Res. 2002; 4(5):191-6.
    View in: PubMed
    Score: 0.002
  67. Effect of selective ablation of proliferating mammary epithelial cells on MNU induced rat mammary tumorigenesis. Breast Cancer Res Treat. 2002 May; 73(1):75-83.
    View in: PubMed
    Score: 0.002
  68. Mechanisms of hormonal prevention of breast cancer. Ann N Y Acad Sci. 2001 Dec; 952:23-35.
    View in: PubMed
    Score: 0.002
  69. p53 is a potential mediator of pregnancy and hormone-induced resistance to mammary carcinogenesis. Proc Natl Acad Sci U S A. 2001 Oct 23; 98(22):12379-84.
    View in: PubMed
    Score: 0.002
  70. The dual function steroid receptor coactivator/ubiquitin protein-ligase integrator E6-AP is overexpressed in mouse mammary tumorigenesis. Breast Cancer Res Treat. 2000 Aug; 62(3):185-95.
    View in: PubMed
    Score: 0.002
  71. Regulation of epidermal Langerhans cell migration by lactoferrin. Immunology. 2000 May; 100(1):21-8.
    View in: PubMed
    Score: 0.002
  72. Reduced Nurr1 expression increases the vulnerability of mesencephalic dopamine neurons to MPTP-induced injury. J Neurochem. 1999 Nov; 73(5):2218-21.
    View in: PubMed
    Score: 0.002
  73. Progesterone receptors in the thymus are required for thymic involution during pregnancy and for normal fertility. Proc Natl Acad Sci U S A. 1999 Oct 12; 96(21):12021-6.
    View in: PubMed
    Score: 0.002
  74. Selective agenesis of mesencephalic dopaminergic neurons in Nurr1-deficient mice. Exp Neurol. 1999 Oct; 159(2):451-8.
    View in: PubMed
    Score: 0.002
  75. Progesterone via its receptor antagonizes the pro-inflammatory activity of estrogen in the mouse uterus. Biol Reprod. 1999 May; 60(5):1158-65.
    View in: PubMed
    Score: 0.002
  76. Hormone-induced refractoriness to mammary carcinogenesis in Wistar-Furth rats. Carcinogenesis. 1998 Sep; 19(9):1573-81.
    View in: PubMed
    Score: 0.002
  77. Reconstitution of estrogen-dependent transcriptional activation of an adenoviral target gene in select regions of the rat mammary gland. Endocrinology. 1998 Jun; 139(6):2916-25.
    View in: PubMed
    Score: 0.002
  78. Endocrine defects in mice carrying a null mutation for the progesterone receptor gene. Endocrinology. 1997 Oct; 138(10):4147-52.
    View in: PubMed
    Score: 0.002
  79. Progesterone, in addition to estrogen, induces cyclin D1 expression in the murine mammary epithelial cell, in vivo. Endocrinology. 1997 Sep; 138(9):3933-9.
    View in: PubMed
    Score: 0.002
  80. Dopamine requires the unoccupied progesterone receptor to induce sexual behavior in mice. Mol Endocrinol. 1996 Dec; 10(12):1728-37.
    View in: PubMed
    Score: 0.002
  81. Reproductive phenotpes of the progesterone receptor null mutant mouse. J Steroid Biochem Mol Biol. 1996 Jan; 56(1-6 Spec No):67-77.
    View in: PubMed
    Score: 0.001
  82. Mice lacking progesterone receptor exhibit pleiotropic reproductive abnormalities. Genes Dev. 1995 Sep 15; 9(18):2266-78.
    View in: PubMed
    Score: 0.001
  83. An alternative ligand-independent pathway for activation of steroid receptors. Recent Prog Horm Res. 1995; 50:333-47.
    View in: PubMed
    Score: 0.001
  84. Molecular cloning of a novel member of the nuclear receptor superfamily related to the orphan receptor, TR2. Gene Expr. 1994; 4(1-2):77-84.
    View in: PubMed
    Score: 0.001
  85. Chicken progesterone receptor expressed in Saccharomyces cerevisiae is correctly phosphorylated at all four Ser-Pro phosphorylation sites. Biochemistry. 1993 Sep 21; 32(37):9563-9.
    View in: PubMed
    Score: 0.001
  86. Identification of a new brain-specific transcription factor, NURR1. Mol Endocrinol. 1992 Dec; 6(12):2129-35.
    View in: PubMed
    Score: 0.001
  87. New insights into activation of the steroid hormone receptor superfamily. Trends Pharmacol Sci. 1992 Aug; 13(8):318-23.
    View in: PubMed
    Score: 0.001
  88. Dopaminergic and ligand-independent activation of steroid hormone receptors. Science. 1991 Dec 13; 254(5038):1636-9.
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    Score: 0.001
  89. Characterization of progesterone receptor binding to the 90- and 70-kDa heat shock proteins. J Biol Chem. 1991 Nov 05; 266(31):21165-73.
    View in: PubMed
    Score: 0.001
  90. Dopamine activation of an orphan of the steroid receptor superfamily. Science. 1991 Jun 14; 252(5012):1546-8.
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    Score: 0.001
  91. High level expression of a truncated chicken progesterone receptor in Escherichia coli. J Biol Chem. 1990 Jan 25; 265(3):1419-24.
    View in: PubMed
    Score: 0.001
  92. In situ detection of progesterone receptor mRNA in the chicken oviduct using probe-on slides. Biotechniques. 1989 Nov-Dec; 7(10):1104-8.
    View in: PubMed
    Score: 0.001
  93. Mutational analysis of the chicken progesterone receptor. J Biol Chem. 1989 Mar 05; 264(7):4207-11.
    View in: PubMed
    Score: 0.001
  94. Interaction of the chicken progesterone receptor with heat shock protein (HSP) 90. J Steroid Biochem. 1989; 34(1-6):1-9.
    View in: PubMed
    Score: 0.001
  95. Structure of the chromosomal chicken progesterone receptor gene. Proc Natl Acad Sci U S A. 1987 Dec; 84(23):8380-4.
    View in: PubMed
    Score: 0.001
  96. Structure-function properties of the chicken progesterone receptor A synthesized from complementary deoxyribonucleic acid. Mol Endocrinol. 1987 Nov; 1(11):791-801.
    View in: PubMed
    Score: 0.001
  97. The progesterone receptor gene maps to human chromosome band 11q13, the site of the mammary oncogene int-2. Proc Natl Acad Sci U S A. 1987 May; 84(9):2877-81.
    View in: PubMed
    Score: 0.001
  98. Molecular cloning of the chicken avidin cDNA. Nucleic Acids Res. 1987 Apr 24; 15(8):3595-606.
    View in: PubMed
    Score: 0.001
  99. Structural organization and regulation of the chicken estrogen receptor. Mol Endocrinol. 1987 Jan; 1(1):25-35.
    View in: PubMed
    Score: 0.001
  100. Amino acid sequence of a chicken heat shock protein derived from the complementary DNA nucleotide sequence. Biochemistry. 1986 Oct 07; 25(20):6244-51.
    View in: PubMed
    Score: 0.001
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.