MICHAEL LEWIS to Signal Transduction
This is a "connection" page, showing publications MICHAEL LEWIS has written about Signal Transduction.
Connection Strength
1.605
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New paradigms for the Hedgehog signaling network in mammary gland development and breast Cancer. Biochim Biophys Acta Rev Cancer. 2017 Aug; 1868(1):315-332.
Score: 0.240
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An essential role for Ga(i2) in Smoothened-stimulated epithelial cell proliferation in the mammary gland. Sci Signal. 2015 Sep 15; 8(394):ra92.
Score: 0.213
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STAT3 signaling is activated preferentially in tumor-initiating cells in claudin-low models of human breast cancer. Stem Cells. 2014 Oct; 32(10):2571-82.
Score: 0.199
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Hedgehog signaling in the normal and neoplastic mammary gland. Curr Drug Targets. 2010 Sep; 11(9):1103-11.
Score: 0.150
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The hedgehog signaling network, mammary stem cells, and breast cancer: connections and controversies. Ernst Schering Found Symp Proc. 2006; (5):181-217.
Score: 0.108
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Hedgehog signaling in mouse mammary gland development and neoplasia. J Mammary Gland Biol Neoplasia. 2001 Jan; 6(1):53-66.
Score: 0.077
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Pharmacological targeting of MYC-regulated IRE1/XBP1 pathway suppresses MYC-driven breast cancer. J Clin Invest. 2018 04 02; 128(4):1283-1299.
Score: 0.063
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Epithelial and non-epithelial Ptch1 play opposing roles to regulate proliferation and morphogenesis of the mouse mammary gland. Development. 2017 04 01; 144(7):1317-1327.
Score: 0.059
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Identifying and targeting tumor-initiating cells in the treatment of breast cancer. Endocr Relat Cancer. 2015 Jun; 22(3):R135-55.
Score: 0.052
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Altered differentiation and paracrine stimulation of mammary epithelial cell proliferation by conditionally activated Smoothened. Dev Biol. 2011 Apr 01; 352(1):116-27.
Score: 0.039
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Activation of Erk by sonic hedgehog independent of canonical hedgehog signalling. Int J Biochem Cell Biol. 2010 Sep; 42(9):1462-71.
Score: 0.037
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Decreased TGFbeta signaling and increased COX2 expression in high risk women with increased mammographic breast density. Breast Cancer Res Treat. 2010 Jan; 119(2):305-14.
Score: 0.034
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Cyclopamine inhibition of human breast cancer cell growth independent of Smoothened (Smo). Breast Cancer Res Treat. 2009 Jun; 115(3):505-21.
Score: 0.032
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MTOR inhibition reversed drug resistance after combination radiation with erlotinib in lung adenocarcinoma. Oncotarget. 2016 Dec 20; 7(51):84688-84694.
Score: 0.029
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Next stop, the twilight zone: hedgehog network regulation of mammary gland development. J Mammary Gland Biol Neoplasia. 2004 Apr; 9(2):165-81.
Score: 0.024
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MAPK4 promotes triple negative breast cancer growth and reduces tumor sensitivity to PI3K blockade. Nat Commun. 2022 01 11; 13(1):245.
Score: 0.021
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The Gli2 transcription factor is required for normal mouse mammary gland development. Dev Biol. 2001 Oct 01; 238(1):133-44.
Score: 0.020
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Spliceosome-targeted therapies trigger an antiviral immune response in triple-negative breast cancer. Cell. 2021 01 21; 184(2):384-403.e21.
Score: 0.019
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VEGF-C mediates tumor growth and metastasis through promoting EMT-epithelial breast cancer cell crosstalk. Oncogene. 2021 02; 40(5):964-979.
Score: 0.019
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Two Sides of the Same Coin: The Role of Developmental pathways and pluripotency factors in normal mammary stem cells and breast cancer metastasis. J Mammary Gland Biol Neoplasia. 2020 06; 25(2):85-102.
Score: 0.018
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Homeobox genes in mammary gland development and neoplasia. Breast Cancer Res. 2000; 2(3):158-69.
Score: 0.018
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Defects in mouse mammary gland development caused by conditional haploinsufficiency of Patched-1. Development. 1999 Nov; 126(22):5181-93.
Score: 0.018
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S100a4-Cre-mediated deletion of Patched1 causes hypogonadotropic hypogonadism: role of pituitary hematopoietic cells in endocrine regulation. JCI Insight. 2019 07 02; 5.
Score: 0.017
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C/EBPd links IL-6 and HIF-1 signaling to promote breast cancer stem cell-associated phenotypes. Oncogene. 2019 05; 38(20):3765-3780.
Score: 0.016
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Combinatorial inhibition of PTPN12-regulated receptors leads to a broadly effective therapeutic strategy in triple-negative breast cancer. Nat Med. 2018 05; 24(4):505-511.
Score: 0.016
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Ubr3, a Novel Modulator of Hh Signaling Affects the Degradation of Costal-2 and Kif7 through Poly-ubiquitination. PLoS Genet. 2016 05; 12(5):e1006054.
Score: 0.014
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Wild-Type N-Ras, Overexpressed in Basal-like Breast Cancer, Promotes Tumor Formation by Inducing IL-8 Secretion via JAK2 Activation. Cell Rep. 2015 Jul 21; 12(3):511-24.
Score: 0.013
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Drug-repositioning screening identified piperlongumine as a direct STAT3 inhibitor with potent activity against breast cancer. Oncogene. 2015 Mar 12; 34(11):1341-53.
Score: 0.012
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Preclinical and clinical studies of gamma secretase inhibitors with docetaxel on human breast tumors. Clin Cancer Res. 2013 Mar 15; 19(6):1512-24.
Score: 0.011
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Cancer stem cell, niche and EGFR decide tumor development and treatment response: A bio-computational simulation study. J Theor Biol. 2011 Jan 21; 269(1):138-49.
Score: 0.009
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Constitutive activation of smoothened leads to female infertility and altered uterine differentiation in the mouse. Biol Reprod. 2010 May; 82(5):991-9.
Score: 0.009