Co-Authors
This is a "connection" page, showing publications co-authored by MARGARET SPITZ and CHRIS AMOS.
Connection Strength
6.993
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BRCA2-branching out too? J Natl Cancer Inst. 2015 May; 107(5).
Score: 0.507
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Multistage analysis of variants in the inflammation pathway and lung cancer risk in smokers. Cancer Epidemiol Biomarkers Prev. 2012 Jul; 21(7):1213-21.
Score: 0.415
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Nicotinic acetylcholine receptor region on chromosome 15q25 and lung cancer risk among African Americans: a case-control study. J Natl Cancer Inst. 2010 Aug 04; 102(15):1199-205.
Score: 0.363
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Cross-ancestry genome-wide meta-analysis of 61,047 cases and 947,237 controls identifies new susceptibility loci contributing to lung cancer. Nat Genet. 2022 08; 54(8):1167-1177.
Score: 0.211
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Rare deleterious germline variants and risk of lung cancer. NPJ Precis Oncol. 2021 Feb 16; 5(1):12.
Score: 0.190
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Is there a genetic basis for lung cancer susceptibility? Recent Results Cancer Res. 1999; 151:3-12.
Score: 0.164
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Rare Variants in Known Susceptibility Loci and Their Contribution to Risk of Lung Cancer. J Thorac Oncol. 2018 10; 13(10):1483-1495.
Score: 0.159
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Focused Analysis of Exome Sequencing Data for Rare Germline Mutations in Familial and Sporadic Lung Cancer. J Thorac Oncol. 2016 Jan; 11(1):52-61.
Score: 0.133
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Role of selected genetic variants in lung cancer risk in African Americans. J Thorac Oncol. 2013 Apr; 8(4):391-7.
Score: 0.110
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Fine-mapping of the 5p15.33, 6p22.1-p21.31, and 15q25.1 regions identifies functional and histology-specific lung cancer susceptibility loci in African-Americans. Cancer Epidemiol Biomarkers Prev. 2013 Feb; 22(2):251-60.
Score: 0.108
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Cotinine conundrum--a step forward but questions remain. J Natl Cancer Inst. 2012 May 16; 104(10):720-2.
Score: 0.103
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A case-control study of a sex-specific association between a 15q25 variant and lung cancer risk. Cancer Epidemiol Biomarkers Prev. 2011 Dec; 20(12):2603-9.
Score: 0.100
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Variants in inflammation genes are implicated in risk of lung cancer in never smokers exposed to second-hand smoke. Cancer Discov. 2011 Oct; 1(5):420-9.
Score: 0.099
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Novel genetic variants in the chromosome 5p15.33 region associate with lung cancer risk. Carcinogenesis. 2011 Oct; 32(10):1493-9.
Score: 0.098
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Evolutionary evidence of the effect of rare variants on disease etiology. Clin Genet. 2011 Mar; 79(3):199-206.
Score: 0.092
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Chipping away at the genetics of smoking behavior. Nat Genet. 2010 May; 42(5):366-8.
Score: 0.090
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Re: Discriminatory accuracy from single-nucleotide polymorphisms in models to predict breast cancer risk. J Natl Cancer Inst. 2009 Dec 16; 101(24):1731-2; author reply 1732.
Score: 0.088
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The CHRNA5-A3 region on chromosome 15q24-25.1 is a risk factor both for nicotine dependence and for lung cancer. J Natl Cancer Inst. 2008 Nov 05; 100(21):1552-6.
Score: 0.081
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Smoking-related genomic signatures in non-small cell lung cancer. Am J Respir Crit Care Med. 2008 Dec 01; 178(11):1164-72.
Score: 0.080
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An expanded risk prediction model for lung cancer. Cancer Prev Res (Phila). 2008 Sep; 1(4):250-4.
Score: 0.080
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Genome-wide association scan of tag SNPs identifies a susceptibility locus for lung cancer at 15q25.1. Nat Genet. 2008 May; 40(5):616-22.
Score: 0.078
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Shifting paradigm of association studies: value of rare single-nucleotide polymorphisms. Am J Hum Genet. 2008 Jan; 82(1):100-12.
Score: 0.077
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Projecting individualized probabilities of developing bladder cancer in white individuals. J Clin Oncol. 2007 Nov 01; 25(31):4974-81.
Score: 0.076
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Seizure 6-like (SEZ6L) gene and risk for lung cancer. Cancer Res. 2007 Sep 01; 67(17):8406-11.
Score: 0.075
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Aggregation of cancer among relatives of never-smoking lung cancer patients. Int J Cancer. 2007 Jul 01; 121(1):111-8.
Score: 0.074
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Interplay between mutagen sensitivity and epidemiological factors in modulatinglung cancer risk. Int J Cancer. 2007 Jun 15; 120(12):2687-95.
Score: 0.074
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A risk model for prediction of lung cancer. J Natl Cancer Inst. 2007 May 02; 99(9):715-26.
Score: 0.073
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Never smokers and lung cancer risk: a case-control study of epidemiological factors. Int J Cancer. 2006 Apr 01; 118(7):1798-804.
Score: 0.068
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Bladder cancer predisposition: a multigenic approach to DNA-repair and cell-cycle-control genes. Am J Hum Genet. 2006 Mar; 78(3):464-79.
Score: 0.067
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Stratifying Lung Adenocarcinoma Risk with Multi-ancestry Polygenic Risk Scores in East Asian Never-Smokers. medRxiv. 2024 Nov 06.
Score: 0.062
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Risk for smoking-related cancer among relatives of lung cancer patients. Cancer Res. 2003 Dec 01; 63(23):8531-5.
Score: 0.058
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Dietary folate intake and lung cancer risk in former smokers: a case-control analysis. Cancer Epidemiol Biomarkers Prev. 2003 Oct; 12(10):980-6.
Score: 0.057
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Telomere dysfunction: a potential cancer predisposition factor. J Natl Cancer Inst. 2003 Aug 20; 95(16):1211-8.
Score: 0.057
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Genetic susceptibility to lung cancer: the role of DNA damage and repair. Cancer Epidemiol Biomarkers Prev. 2003 Aug; 12(8):689-98.
Score: 0.056
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Genome-wide association study of lung adenocarcinoma in East Asia and comparison with a European population. Nat Commun. 2023 05 26; 14(1):3043.
Score: 0.056
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XPA polymorphism associated with reduced lung cancer risk and a modulating effect on nucleotide excision repair capacity. Carcinogenesis. 2003 Mar; 24(3):505-9.
Score: 0.055
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An analysis of DNA repair as a determinant of survival in patients with non-small-cell lung cancer. J Natl Cancer Inst. 2002 Jul 17; 94(14):1091-9.
Score: 0.052
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p53 Genotypes and Haplotypes Associated With Lung Cancer Susceptibility and Ethnicity. J Natl Cancer Inst. 2002 May 01; 94(9):681-90.
Score: 0.052
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The association of microsomal epoxide hydrolase polymorphisms and lung cancer risk in African-Americans and Mexican-Americans. Carcinogenesis. 2001 Jun; 22(6):923-8.
Score: 0.049
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Discovery and fine-mapping of height loci via high-density imputation of GWASs in individuals of African ancestry. Am J Hum Genet. 2021 04 01; 108(4):564-582.
Score: 0.048
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Modulation of nucleotide excision repair capacity by XPD polymorphisms in lung cancer patients. Cancer Res. 2001 Feb 15; 61(4):1354-7.
Score: 0.048
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Leptin and prostate cancer. Prostate. 2001 Jan 01; 46(1):62-7.
Score: 0.047
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Repair of tobacco carcinogen-induced DNA adducts and lung cancer risk: a molecular epidemiologic study. J Natl Cancer Inst. 2000 Nov 01; 92(21):1764-72.
Score: 0.047
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Dietary intake of isothiocyanates: evidence of a joint effect with glutathione S-transferase polymorphisms in lung cancer risk. Cancer Epidemiol Biomarkers Prev. 2000 Oct; 9(10):1017-20.
Score: 0.046
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Epidemiologic determinants of clinically relevant prostate cancer. Int J Cancer. 2000 May 20; 89(3):259-64.
Score: 0.045
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Joint effect of insulin-like growth factors and mutagen sensitivity in lung cancer risk. J Natl Cancer Inst. 2000 May 03; 92(9):737-43.
Score: 0.045
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Joint effect of insulin-like growth factors and mutagen sensitivity in lung cancer risk. Growth Horm IGF Res. 2000 Apr; 10 Suppl A:S26-7.
Score: 0.045
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Associations among telomerase activity, p53 protein overexpression, and genetic instability in lung cancer. Br J Cancer. 1999 May; 80(3-4):453-7.
Score: 0.042
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Lung Cancer Risk in Never-Smokers of European Descent is Associated With Genetic Variation in the 5p15.33 TERT-CLPTM1Ll Region. J Thorac Oncol. 2019 08; 14(8):1360-1369.
Score: 0.042
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Cross-Cancer Pleiotropic Associations with Lung Cancer Risk in African Americans. Cancer Epidemiol Biomarkers Prev. 2019 04; 28(4):715-723.
Score: 0.042
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Chromosome 5 aberrations and genetic predisposition to lung cancer. Int J Cancer. 1998 Oct 23; 79(5):490-3.
Score: 0.041
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Benzo[a]pyrene diol epoxide and bleomycin sensitivity and susceptibility to cancer of upper aerodigestive tract. J Natl Cancer Inst. 1998 Sep 16; 90(18):1393-9.
Score: 0.040
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A parallel study of in vitro sensitivity to benzo[a]pyrene diol epoxide and bleomycin in lung carcinoma cases and controls. Cancer. 1998 Sep 15; 83(6):1118-27.
Score: 0.040
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Case-control study of the D2 dopamine receptor gene and smoking status in lung cancer patients. J Natl Cancer Inst. 1998 Mar 04; 90(5):358-63.
Score: 0.039
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Cytochrome P450 2E1 DraI polymorphisms in lung cancer in minority populations. Cancer Epidemiol Biomarkers Prev. 1998 Jan; 7(1):13-8.
Score: 0.038
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Deletion in poly(ADP-ribose)polymerase pseudogene and lung cancer risk. Carcinogenesis. 1998 Jan; 19(1):93-8.
Score: 0.038
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A clinical trial to evaluate the effect of vitamin C supplementation on in vitro mutagen sensitivity. The University of Texas M. D. Anderson Clinical Community Oncology Program Network. Cancer Epidemiol Biomarkers Prev. 1997 Jul; 6(7):537-42.
Score: 0.037
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Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes. Nat Genet. 2017 Jul; 49(7):1126-1132.
Score: 0.037
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Corrigendum: Rare variants of large effect in BRCA2 and CHEK2 affect risk of lung cancer. Nat Genet. 2017 03 30; 49(4):651.
Score: 0.036
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Genetic Risk Can Be Decreased: Quitting Smoking Decreases and Delays Lung Cancer for Smokers With High and Low CHRNA5 Risk Genotypes - A Meta-Analysis. EBioMedicine. 2016 Sep; 11:219-226.
Score: 0.035
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Erratum to: Hierarchical modeling identifies novel lung cancer susceptibility variants in inflammation pathways among 10,140 cases and 11,012 controls. Hum Genet. 2016 08; 135(8):963.
Score: 0.035
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Female chromosome X mosaicism is age-related and preferentially affects the inactivated X chromosome. Nat Commun. 2016 06 13; 7:11843.
Score: 0.034
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Genome-wide association study confirms lung cancer susceptibility loci on chromosomes 5p15 and 15q25 in an African-American population. Lung Cancer. 2016 08; 98:33-42.
Score: 0.034
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Gene by Environment Investigation of Incident Lung Cancer Risk in African-Americans. EBioMedicine. 2016 Feb; 4:153-61.
Score: 0.033
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Identification of lung cancer histology-specific variants applying Bayesian framework variant prioritization approaches within the TRICL and ILCCO consortia. Carcinogenesis. 2015 Nov; 36(11):1314-26.
Score: 0.033
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Higher lung cancer risk for younger African-Americans with the Pro/Pro p53 genotype. Carcinogenesis. 1995 Sep; 16(9):2205-8.
Score: 0.033
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Cross Cancer Genomic Investigation of Inflammation Pathway for Five Common Cancers: Lung, Ovary, Prostate, Breast, and Colorectal Cancer. J Natl Cancer Inst. 2015 Nov; 107(11).
Score: 0.033
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CHRNA5 risk variant predicts delayed smoking cessation and earlier lung cancer diagnosis--a meta-analysis. J Natl Cancer Inst. 2015 May; 107(5).
Score: 0.032
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Characterization of large structural genetic mosaicism in human autosomes. Am J Hum Genet. 2015 Mar 05; 96(3):487-97.
Score: 0.032
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Mutagen sensitivity as a biological marker of lung cancer risk in African Americans. Cancer Epidemiol Biomarkers Prev. 1995 Mar; 4(2):99-103.
Score: 0.031
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A case-control study of nonrandom distribution of bleomycin-induced chromatid breaks in lymphocytes of lung cancer cases. Cancer Res. 1995 Feb 01; 55(3):557-61.
Score: 0.031
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A recurrent mutation in PARK2 is associated with familial lung cancer. Am J Hum Genet. 2015 Feb 05; 96(2):301-8.
Score: 0.031
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Informed genome-wide association analysis with family history as a secondary phenotype identifies novel loci of lung cancer. Genet Epidemiol. 2015 Mar; 39(3):197-206.
Score: 0.031
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Mutagen sensitivity as a risk factor for second malignant tumors following malignancies of the upper aerodigestive tract. J Natl Cancer Inst. 1994 Nov 16; 86(22):1681-4.
Score: 0.031
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Genome-wide scan of 29,141 African Americans finds no evidence of directional selection since admixture. Am J Hum Genet. 2014 Oct 02; 95(4):437-44.
Score: 0.031
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Imputation and subset-based association analysis across different cancer types identifies multiple independent risk loci in the TERT-CLPTM1L region on chromosome 5p15.33. Hum Mol Genet. 2014 Dec 15; 23(24):6616-33.
Score: 0.030
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Rare variants of large effect in BRCA2 and CHEK2 affect risk of lung cancer. Nat Genet. 2014 Jul; 46(7):736-41.
Score: 0.030
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Distinct loci in the CHRNA5/CHRNA3/CHRNB4 gene cluster are associated with onset of regular smoking. Genet Epidemiol. 2013 Dec; 37(8):846-59.
Score: 0.029
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Pilot study of CYP2B6 genetic variation to explore the contribution of nitrosamine activation to lung carcinogenesis. Int J Mol Sci. 2013 Apr 16; 14(4):8381-92.
Score: 0.028
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A meta-analysis identifies new loci associated with body mass index in individuals of African ancestry. Nat Genet. 2013 Jun; 45(6):690-6.
Score: 0.028
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Hierarchical modeling identifies novel lung cancer susceptibility variants in inflammation pathways among 10,140 cases and 11,012 controls. Hum Genet. 2013 05; 132(5):579-89.
Score: 0.027
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Association study of nicotinic acetylcholine receptor genes identifies a novel lung cancer susceptibility locus near CHRNA1 in African-Americans. Oncotarget. 2012 Nov; 3(11):1428-38.
Score: 0.027
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Genome-wide association study reveals novel genetic determinants of DNA repair capacity in lung cancer. Cancer Res. 2013 Jan 01; 73(1):256-64.
Score: 0.027
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Method for evaluating multiple mediators: mediating effects of smoking and COPD on the association between the CHRNA5-A3 variant and lung cancer risk. PLoS One. 2012; 7(10):e47705.
Score: 0.027
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Influence of common genetic variation on lung cancer risk: meta-analysis of 14 900 cases and 29 485 controls. Hum Mol Genet. 2012 Nov 15; 21(22):4980-95.
Score: 0.026
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Increased genetic vulnerability to smoking at CHRNA5 in early-onset smokers. Arch Gen Psychiatry. 2012 Aug; 69(8):854-60.
Score: 0.026
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Genome-wide gene-environment interaction analysis for asbestos exposure in lung cancer susceptibility. Carcinogenesis. 2012 Aug; 33(8):1531-7.
Score: 0.026
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Detectable clonal mosaicism and its relationship to aging and cancer. Nat Genet. 2012 May 06; 44(6):651-8.
Score: 0.026
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Smoking and genetic risk variation across populations of European, Asian, and African American ancestry--a meta-analysis of chromosome 15q25. Genet Epidemiol. 2012 May; 36(4):340-51.
Score: 0.026
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Derived SNP alleles are used more frequently than ancestral alleles as risk-associated variants in common human diseases. J Bioinform Comput Biol. 2012 Apr; 10(2):1241008.
Score: 0.026
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Comparison of pathway analysis approaches using lung cancer GWAS data sets. PLoS One. 2012; 7(2):e31816.
Score: 0.026
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Genetic variants on 15q25.1, smoking, and lung cancer: an assessment of mediation and interaction. Am J Epidemiol. 2012 May 15; 175(10):1013-20.
Score: 0.025
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Inherited variation at chromosome 12p13.33, including RAD52, influences the risk of squamous cell lung carcinoma. Cancer Discov. 2012 Feb; 2(2):131-9.
Score: 0.025
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DNA repair capacity in peripheral lymphocytes predicts survival of patients with non-small-cell lung cancer treated with first-line platinum-based chemotherapy. J Clin Oncol. 2011 Nov 01; 29(31):4121-8.
Score: 0.025
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Relationship between CYP2A6 and CHRNA5-CHRNA3-CHRNB4 variation and smoking behaviors and lung cancer risk. J Natl Cancer Inst. 2011 Sep 07; 103(17):1342-6.
Score: 0.024
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A Genome-wide Association Study of Lung Cancer Identifies a Region of Chromosome 5p15 Associated with Risk for Adenocarcinoma. Am J Hum Genet. 2011 Jun 10; 88(6):861.
Score: 0.024
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Association of smoking with tumor size at diagnosis in non-small cell lung cancer. Lung Cancer. 2011 Dec; 74(3):378-83.
Score: 0.024
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Genome-wide association study of survival in non-small cell lung cancer patients receiving platinum-based chemotherapy. J Natl Cancer Inst. 2011 May 18; 103(10):817-25.
Score: 0.024
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An analysis of single nucleotide polymorphisms of 125 DNA repair genes in the Texas genome-wide association study of lung cancer with a replication for the XRCC4 SNPs. DNA Repair (Amst). 2011 Apr 03; 10(4):398-407.
Score: 0.024
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Association of a novel functional promoter variant (rs2075533 C>T) in the apoptosis gene TNFSF8 with risk of lung cancer--a finding from Texas lung cancer genome-wide association study. Carcinogenesis. 2011 Apr; 32(4):507-15.
Score: 0.024
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Admixture mapping of lung cancer in 1812 African-Americans. Carcinogenesis. 2011 Mar; 32(3):312-7.
Score: 0.023
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Multiple independent loci at chromosome 15q25.1 affect smoking quantity: a meta-analysis and comparison with lung cancer and COPD. PLoS Genet. 2010 Aug 05; 6(8).
Score: 0.023
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Mediating effects of smoking and chronic obstructive pulmonary disease on the relation between the CHRNA5-A3 genetic locus and lung cancer risk. Cancer. 2010 Jul 15; 116(14):3458-62.
Score: 0.023
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Replication of lung cancer susceptibility loci at chromosomes 15q25, 5p15, and 6p21: a pooled analysis from the International Lung Cancer Consortium. J Natl Cancer Inst. 2010 Jul 07; 102(13):959-71.
Score: 0.023
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Evaluation of association of HNF1B variants with diverse cancers: collaborative analysis of data from 19 genome-wide association studies. PLoS One. 2010 May 28; 5(5):e10858.
Score: 0.023
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Reduced DNA repair capacity for removing tobacco carcinogen-induced DNA adducts contributes to risk of head and neck cancer but not tumor characteristics. Clin Cancer Res. 2010 Jan 15; 16(2):764-74.
Score: 0.022
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A genome-wide association study of lung cancer identifies a region of chromosome 5p15 associated with risk for adenocarcinoma. Am J Hum Genet. 2009 11; 85(5):679-91.
Score: 0.022
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Deciphering the impact of common genetic variation on lung cancer risk: a genome-wide association study. Cancer Res. 2009 Aug 15; 69(16):6633-41.
Score: 0.021
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Common 5p15.33 and 6p21.33 variants influence lung cancer risk. Nat Genet. 2008 Dec; 40(12):1407-9.
Score: 0.020
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Familial aggregation of common sequence variants on 15q24-25.1 in lung cancer. J Natl Cancer Inst. 2008 Sep 17; 100(18):1326-30.
Score: 0.020
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Mitochondrial DNA content: its genetic heritability and association with renal cell carcinoma. J Natl Cancer Inst. 2008 Aug 06; 100(15):1104-12.
Score: 0.020
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Trends in prevalence of prognostic factors and survival in lung cancer patients from 1985 to 2004 at a tertiary care center. Cancer Detect Prev. 2008; 32(2):101-8.
Score: 0.020
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DNA repair capacity and lung cancer risk in never smokers. Cancer Epidemiol Biomarkers Prev. 2008 Jun; 17(6):1322-8.
Score: 0.020
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Mutagen sensitivity and genetic variants in nucleotide excision repair pathway: genotype-phenotype correlation. Cancer Epidemiol Biomarkers Prev. 2007 Oct; 16(10):2065-71.
Score: 0.019
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Polymorphisms of FAS and FAS ligand genes involved in the death pathway and risk and progression of squamous cell carcinoma of the head and neck. Clin Cancer Res. 2006 Sep 15; 12(18):5596-602.
Score: 0.018
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Mutagen sensitivity has high heritability: evidence from a twin study. Cancer Res. 2006 Jun 15; 66(12):5993-6.
Score: 0.017
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In vitro sensitivity to ultraviolet B light and skin cancer risk: a case-control analysis. J Natl Cancer Inst. 2005 Dec 21; 97(24):1822-31.
Score: 0.017
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Relationship between plasma carotenoids and prostate cancer. Nutr Cancer. 2005; 53(2):127-34.
Score: 0.016
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Complex segregation analysis reveals a multigene model for lung cancer. Hum Genet. 2005 Jan; 116(1-2):121-7.
Score: 0.015
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p73 G4C14-to-A4T14 polymorphism and risk of lung cancer. Cancer Res. 2004 Oct 01; 64(19):6863-6.
Score: 0.015
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Association of a p73 exon 2 G4C14-to-A4T14 polymorphism with risk of squamous cell carcinoma of the head and neck. Carcinogenesis. 2004 Oct; 25(10):1911-6.
Score: 0.015
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An evolutionary perspective on single-nucleotide polymorphism screening in molecular cancer epidemiology. Cancer Res. 2004 Mar 15; 64(6):2251-7.
Score: 0.015
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Smoking, DNA repair capacity and risk of nonsmall cell lung cancer. Int J Cancer. 2003 Oct 20; 107(1):84-8.
Score: 0.014
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XRCC3 genetic polymorphism, smoking, and lung carcinoma risk in minority populations. Cancer. 2003 Oct 15; 98(8):1701-6.
Score: 0.014
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Repair of UV light-induced DNA damage and risk of cutaneous malignant melanoma. J Natl Cancer Inst. 2003 Feb 19; 95(4):308-15.
Score: 0.014
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A case-control analysis of lymphocytic chromosome 9 aberrations in lung cancer. Int J Cancer. 2002 Dec 10; 102(5):536-40.
Score: 0.013
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Chromosome breaks and sister chromatid exchange as predictors of second cancers in Hodgkin's disease. Leuk Lymphoma. 1998 Feb; 28(5-6):561-6.
Score: 0.010