PETER HOTEZ to Necator americanus
This is a "connection" page, showing publications PETER HOTEZ has written about Necator americanus.
Connection Strength
6.203
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Molecular cloning, biochemical characterization, and partial protective immunity of the heme-binding glutathione S-transferases from the human hookworm Necator americanus. Infect Immun. 2010 Apr; 78(4):1552-63.
Score: 0.301
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Crystallization and preliminary X-ray analysis of Na-SAA-2 from the human hookworm parasite Necator americanus. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2010 Feb 01; 66(Pt 2):172-6.
Score: 0.300
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Randomized, placebo-controlled, double-blind trial of the Na-ASP-2 hookworm vaccine in unexposed adults. Vaccine. 2008 May 02; 26(19):2408-17.
Score: 0.263
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Hookworm vaccines. Clin Infect Dis. 2008 Jan 15; 46(2):282-8.
Score: 0.261
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The evaluation of recombinant hookworm antigens as vaccines in hamsters (Mesocricetus auratus) challenged with human hookworm, Necator americanus. Exp Parasitol. 2008 Jan; 118(1):32-40.
Score: 0.250
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Na-GST-1 adsorbed on Alhydrogel co-administered with different Toll-like receptor agonists in hookworm-naive adults using a controlled human infection model in the USA: a phase 2, double-blind, randomised controlled trial. Lancet Infect Dis. 2026 Jul; 26(7):692-704.
Score: 0.230
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Expression of the Necator americanus hookworm larval antigen Na-ASP-2 in Pichia pastoris and purification of the recombinant protein for use in human clinical trials. Vaccine. 2005 Sep 15; 23(39):4754-64.
Score: 0.222
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Antibodies against a secreted protein from hookworm larvae reduce the intensity of hookworm infection in humans and vaccinated laboratory animals. FASEB J. 2005 Oct; 19(12):1743-5.
Score: 0.219
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Crystallization and preliminary X-ray analysis of Na-ASP-1, a multi-domain pathogenesis-related-1 protein from the human hookworm parasite Necator americanus. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2005 Apr 01; 61(Pt 4):391-4.
Score: 0.215
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X-ray structure of Na-ASP-2, a pathogenesis-related-1 protein from the nematode parasite, Necator americanus, and a vaccine antigen for human hookworm infection. J Mol Biol. 2005 Feb 25; 346(3):801-14.
Score: 0.212
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Altering the intracellular trafficking of Necator americanus GST-1 antigen yields novel hookworm mRNA vaccine candidates. PLoS Negl Trop Dis. 2025 Jan; 19(1):e0012809.
Score: 0.212
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Randomized, observer-blind, controlled Phase 1 study of the safety and immunogenicity of the Na-GST-1/Alhydrogel hookworm vaccine with or without a CpG ODN adjuvant in hookworm-na?ve adults. PLoS Negl Trop Dis. 2024 12; 18(12):e0012788.
Score: 0.211
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Safety and immunogenicity of the co-administered Na-APR-1 and Na-GST-1 hookworm vaccines in school-aged children in Gabon: a randomised, controlled, observer-blind, phase 1, dose-escalation trial. Lancet Infect Dis. 2024 07; 24(7):760-774.
Score: 0.200
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Emerging patterns of hookworm infection: influence of aging on the intensity of Necator infection in Hainan Province, People's Republic of China. Clin Infect Dis. 2002 Dec 01; 35(11):1336-44.
Score: 0.182
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Epidemiology of Necator americanus hookworm infections in Xiulongkan Village, Hainan Province, China: high prevalence and intensity among middle-aged and elderly residents. J Parasitol. 2001 Aug; 87(4):739-43.
Score: 0.167
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Safety and immunogenicity of co-administered hookworm vaccine candidates Na-GST-1 and Na-APR-1 in Gabonese adults: a randomised, controlled, double-blind, phase 1 dose-escalation trial. Lancet Infect Dis. 2021 02; 21(2):275-285.
Score: 0.157
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Hookworm burden reductions in BALB/c mice vaccinated with recombinant Ancylostoma secreted proteins (ASPs) from Ancylostoma duodenale, Ancylostoma caninum and Necator americanus. Vaccine. 2000 Jan 06; 18(11-12):1096-102.
Score: 0.149
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Construction and analysis of cDNA library of Necator americanus third stage larvae. Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi. 2000; 18(1):26-8.
Score: 0.149
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Ancylostoma secreted protein 1 (ASP-1) homologues in human hookworms. Mol Biochem Parasitol. 1999 Jan 05; 98(1):143-9.
Score: 0.139
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[Sequencing of cytochrome C oxidase 1 gene of Ancylostoma duodenale and Necator americanus]. Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi. 1999; 17(2):81-3.
Score: 0.139
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A novel blood-feeding detoxification pathway in Nippostrongylus brasiliensis L3 reveals a potential checkpoint for arresting hookworm development. PLoS Pathog. 2018 03; 14(3):e1006931.
Score: 0.132
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Advancing a vaccine to prevent hookworm disease and anemia. Vaccine. 2016 06 03; 34(26):3001-3005.
Score: 0.115
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Expression, purification, and characterization of the Necator americanus aspartic protease-1 (Na-APR-1 (M74)) antigen, a component of the bivalent human hookworm vaccine. Hum Vaccin Immunother. 2015; 11(6):1474-88.
Score: 0.106
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Genome of the human hookworm Necator americanus. Nat Genet. 2014 Mar; 46(3):261-269.
Score: 0.099
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Optimization and revision of the production process of the Necator americanus glutathione S-transferase 1 (Na-GST-1), the lead hookworm vaccine recombinant protein candidate. Hum Vaccin Immunother. 2014; 10(7):1914-25.
Score: 0.099
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Fusion of Na-ASP-2 with human immunoglobulin Fc? abrogates histamine release from basophils sensitized with anti-Na-ASP-2 IgE. Parasite Immunol. 2012 Aug-Sep; 34(8-9):404-11.
Score: 0.089
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Generalized urticaria induced by the Na-ASP-2 hookworm vaccine: implications for the development of vaccines against helminths. J Allergy Clin Immunol. 2012 Jul; 130(1):169-76.e6.
Score: 0.088
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Expression, purification, and molecular analysis of the Necator americanus glutathione S-transferase 1 (Na-GST-1): a production process developed for a lead candidate recombinant hookworm vaccine antigen. Protein Expr Purif. 2012 Jun; 83(2):145-51.
Score: 0.087
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Acquired hookworm immunity in the golden hamster (Mesocricetus auratus) elicited by living Necator americanus third-stage infective larvae. Exp Parasitol. 2012 Jan; 130(1):6-12.
Score: 0.085
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Developing vaccines to combat hookworm infection and intestinal schistosomiasis. Nat Rev Microbiol. 2010 Nov; 8(11):814-26.
Score: 0.079
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Potency testing for the experimental Na-GST-1 hookworm vaccine. Expert Rev Vaccines. 2010 Oct; 9(10):1219-30.
Score: 0.079
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Neutralizing antibodies to the hookworm hemoglobinase Na-APR-1: implications for a multivalent vaccine against hookworm infection and schistosomiasis. J Infect Dis. 2010 May 15; 201(10):1561-9.
Score: 0.077
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An enzymatically inactivated hemoglobinase from Necator americanus induces neutralizing antibodies against multiple hookworm species and protects dogs against heterologous hookworm infection. FASEB J. 2009 Sep; 23(9):3007-19.
Score: 0.071
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Proteolytic degradation of hemoglobin in the intestine of the human hookworm Necator americanus. J Infect Dis. 2009 Mar 15; 199(6):904-12.
Score: 0.071
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A family of cathepsin B cysteine proteases expressed in the gut of the human hookworm, Necator americanus. Mol Biochem Parasitol. 2008 Aug; 160(2):90-9.
Score: 0.066
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Use of the air pouch model to investigate immune responses to a hookworm vaccine containing the Na-ASP-2 protein in rats. Parasite Immunol. 2008 Jan; 30(1):53-6.
Score: 0.065
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Protective immunity elicited by ultraviolet-irradiated third-stage infective hookworm (Necator americanus and Ancylostoma caninum) larvae in mice and hamsters. Southeast Asian J Trop Med Public Health. 2006 Sep; 37(5):885-95.
Score: 0.059
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Necator americanus: optimization of the golden hamster model for testing anthelmintic drugs. Exp Parasitol. 2005 Dec; 111(4):219-23.
Score: 0.056
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Immunogenicity of the hookworm Na-ASP-2 vaccine candidate: characterization of humoral and cellular responses after vaccination in the Sprague Dawley rat. Hum Vaccin. 2005 May-Jun; 1(3):123-8.
Score: 0.054
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A secreted protein from the human hookworm necator americanus binds selectively to NK cells and induces IFN-gamma production. J Immunol. 2004 Aug 15; 173(4):2699-704.
Score: 0.051
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Necator americanus: maintenance through one hundred generations in golden hamsters (Mesocricetus auratus). II. Morphological development of the adult and its comparison with humans. Exp Parasitol. 2003 Nov-Dec; 105(3-4):192-200.
Score: 0.049
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Necator americanus: maintenance through one hundred generations in golden hamsters (Mesocricetus auratus). I. Host sex-associated differences in hookworm burden and fecundity. Exp Parasitol. 2003 May-Jun; 104(1-2):62-6.
Score: 0.047
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Hookworm aspartic protease, Na-APR-2, cleaves human hemoglobin and serum proteins in a host-specific fashion. J Infect Dis. 2003 Feb 01; 187(3):484-94.
Score: 0.046
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Epidemiology of human hookworm infections among adult villagers in Hejiang and Santai Counties, Sichuan Province, China. Acta Trop. 1999 Oct 15; 73(3):243-9.
Score: 0.037
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Experimental approaches to the development of a recombinant hookworm vaccine. Immunol Rev. 1999 Oct; 171:163-71.
Score: 0.037
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Epidemiology of human intestinal nematode infections in Wujiang and Pizhou counties, Jiangsu Province, China. Southeast Asian J Trop Med Public Health. 1998 Sep; 29(3):605-10.
Score: 0.034
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Human Intestinal Parasite Burden and Poor Sanitation in Rural Alabama. Am J Trop Med Hyg. 2017 Nov; 97(5):1623-1628.
Score: 0.032
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Hookworm infection. Nat Rev Dis Primers. 2016 12 08; 2:16088.
Score: 0.030
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Hookworm infection. Sci Am. 1995 Jun; 272(6):68-74.
Score: 0.027
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Advances in vaccines against neglected tropical diseases: enhancing physical stability of a recombinant hookworm vaccine through biophysical and formulation studies. Hum Vaccin Immunother. 2012 Jun; 8(6):765-76.
Score: 0.022
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A history of hookworm vaccine development. Hum Vaccin. 2011 Nov; 7(11):1234-44.
Score: 0.021
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Age-related changes in hookworm infection, anaemia and iron deficiency in an area of high Necator americanus hookworm transmission in south-eastern Brazil. Trans R Soc Trop Med Hyg. 2007 Feb; 101(2):146-54.
Score: 0.015