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THOMAS KOSTEN to Double-Blind Method

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This is a "connection" page, showing publications THOMAS KOSTEN has written about Double-Blind Method.
THOMAS KOSTEN
Connection Strength
3.242
Double-Blind Method
  1. Dexmedetomidine HCL (BXCL501) as a potential treatment for alcohol use disorder and comorbid PTSD: A phase 1b, placebo-controlled crossover laboratory study. Am J Addict. 2025 Jan; 34(1):7-14.
    View in: PubMed
    Score: 0.167
  2. Ginkgo biloba for Tardive Dyskinesia and Plasma MnSOD Activity: Association with MnSOD Ala-9Val Variant: A Randomized, Double-blind Trial. Curr Neuropharmacol. 2024; 22(14):2443-2452.
    View in: PubMed
    Score: 0.160
  3. Pharmacogenetics of Dopamine ?-Hydroxylase in cocaine dependence therapy with doxazosin. Addict Biol. 2019 05; 24(3):531-538.
    View in: PubMed
    Score: 0.107
  4. Dopamine D3 receptor-preferring agonist enhances the subjective effects of cocaine in humans. Psychiatry Res. 2015 Nov 30; 230(1):44-9.
    View in: PubMed
    Score: 0.089
  5. Vaccine for cocaine dependence: a randomized double-blind placebo-controlled efficacy trial. Drug Alcohol Depend. 2014 Jul 01; 140:42-7.
    View in: PubMed
    Score: 0.082
  6. Randomized clinical trial of disulfiram for cocaine dependence or abuse during buprenorphine treatment. Drug Alcohol Depend. 2014 Mar 01; 136:36-42.
    View in: PubMed
    Score: 0.080
  7. Naltrexone with or without guanfacine for preventing relapse to opiate addiction in St.-Petersburg, Russia. Drug Alcohol Depend. 2013 Oct 01; 132(3):674-80.
    View in: PubMed
    Score: 0.077
  8. Spontaneous development of IgM anti-cocaine antibodies in habitual cocaine users: effect on IgG antibody responses to a cocaine cholera toxin B conjugate vaccine. Am J Addict. 2013 Mar-Apr; 22(2):169-74.
    View in: PubMed
    Score: 0.075
  9. Short-term tropisetron treatment and cognitive and P50 auditory gating deficits in schizophrenia. Am J Psychiatry. 2012 Sep; 169(9):974-81.
    View in: PubMed
    Score: 0.073
  10. Effects of risperidone and haloperidol on superoxide dismutase and nitric oxide in schizophrenia. Neuropharmacology. 2012 Apr; 62(5-6):1928-34.
    View in: PubMed
    Score: 0.070
  11. Sertraline delays relapse in recently abstinent cocaine-dependent patients with depressive symptoms. Addiction. 2012 Jan; 107(1):131-41.
    View in: PubMed
    Score: 0.069
  12. Cocaine vaccine for the treatment of cocaine dependence in methadone-maintained patients: a randomized, double-blind, placebo-controlled efficacy trial. Arch Gen Psychiatry. 2009 Oct; 66(10):1116-23.
    View in: PubMed
    Score: 0.060
  13. Superoxide dismutase and cytokines in chronic patients with schizophrenia: association with psychopathology and response to antipsychotics. Psychopharmacology (Berl). 2009 May; 204(1):177-84.
    View in: PubMed
    Score: 0.057
  14. Progesterone effects on cocaine use in male cocaine users maintained on methadone: a randomized, double-blind, pilot study. Exp Clin Psychopharmacol. 2007 Oct; 15(5):453-60.
    View in: PubMed
    Score: 0.052
  15. Effects of lofexidine on stress-induced and cue-induced opioid craving and opioid abstinence rates: preliminary findings. Psychopharmacology (Berl). 2007 Mar; 190(4):569-74.
    View in: PubMed
    Score: 0.049
  16. Cue-induced brain activity changes and relapse in cocaine-dependent patients. Neuropsychopharmacology. 2006 Mar; 31(3):644-50.
    View in: PubMed
    Score: 0.046
  17. Six-month trial of bupropion with contingency management for cocaine dependence in a methadone-maintained population. Arch Gen Psychiatry. 2006 Feb; 63(2):219-28.
    View in: PubMed
    Score: 0.046
  18. Effects of topiramate in combination with intravenous nicotine in overnight abstinent smokers. Psychopharmacology (Berl). 2006 Mar; 184(3-4):645-51.
    View in: PubMed
    Score: 0.046
  19. Cocaine withdrawal symptoms predict medication response in cocaine users. Am J Drug Alcohol Abuse. 2006; 32(4):617-27.
    View in: PubMed
    Score: 0.046
  20. Effects of tiagabine in combination with intravenous nicotine in overnight abstinent smokers. Psychopharmacology (Berl). 2005 Sep; 181(3):504-10.
    View in: PubMed
    Score: 0.045
  21. Efficacy of dose and contingency management procedures in LAAM-maintained cocaine-dependent patients. Drug Alcohol Depend. 2005 Aug 01; 79(2):157-65.
    View in: PubMed
    Score: 0.045
  22. Long-Term Safety and Efficacy of Esmethadone in Patients With Major Depressive Disorder: Findings From a 12-Month Open-Label Study. J Clin Psychiatry. 2025 Feb 17; 86(1).
    View in: PubMed
    Score: 0.043
  23. Transcranial Direct Current Stimulation Combined With Repetitive Transcranial Magnetic Stimulation for Depression: A Randomized Clinical Trial. JAMA Netw Open. 2024 11 04; 7(11):e2444306.
    View in: PubMed
    Score: 0.042
  24. Effects of progesterone treatment on cocaine responses in male and female cocaine users. Pharmacol Biochem Behav. 2004 Aug; 78(4):699-705.
    View in: PubMed
    Score: 0.042
  25. Cognitive enhancing effect of rTMS combined with tDCS in patients with major depressive disorder: a double-blind, randomized, sham-controlled study. BMC Med. 2024 06 20; 22(1):253.
    View in: PubMed
    Score: 0.041
  26. Efficacy and Safety of Esmethadone (REL-1017) in Patients With Major Depressive Disorder and Inadequate Response to Standard Antidepressants: A Phase 3 Randomized Controlled Trial. J Clin Psychiatry. 2024 Jun 17; 85(3).
    View in: PubMed
    Score: 0.041
  27. Tiagabine increases cocaine-free urines in cocaine-dependent methadone-treated patients: results of a randomized pilot study. Addiction. 2003 Nov; 98(11):1625-32.
    View in: PubMed
    Score: 0.040
  28. A double-blind, randomized controlled study of the effects of celecoxib on clinical symptoms and cognitive impairment in patients with drug-na?ve first episode schizophrenia: pharmacogenetic impact of cyclooxygenase-2 functional polymorphisms. Neuropsychopharmacology. 2024 Apr; 49(5):893-902.
    View in: PubMed
    Score: 0.040
  29. Aspirin or amiloride for cerebral perfusion defects in cocaine dependence. Drug Alcohol Depend. 2003 Aug 20; 71(2):187-94.
    View in: PubMed
    Score: 0.039
  30. Comorbid major depressive disorder as a prognostic factor in cocaine-abusing buprenorphine-maintained patients treated with desipramine and contingency management. Am J Drug Alcohol Abuse. 2003 Aug; 29(3):497-514.
    View in: PubMed
    Score: 0.039
  31. The novel uncompetitive NMDA receptor antagonist esmethadone (REL-1017) has no meaningful abuse potential in recreational drug users. Transl Psychiatry. 2023 06 07; 13(1):192.
    View in: PubMed
    Score: 0.038
  32. A placebo controlled trial of bupropion for smoking cessation in schizophrenia. Biol Psychiatry. 2002 Jul 01; 52(1):53-61.
    View in: PubMed
    Score: 0.036
  33. Low-Dose Ziprasidone in Combination with Sertraline for First-Episode Drug-Na?ve Patients with Schizophrenia: a Randomized Controlled Trial. Neurotherapeutics. 2022 04; 19(3):1037-1046.
    View in: PubMed
    Score: 0.036
  34. Ketoconazole increases cocaine and opioid use in methadone maintained patients. Drug Alcohol Depend. 2002 Apr 01; 66(2):173-80.
    View in: PubMed
    Score: 0.035
  35. Human therapeutic cocaine vaccine: safety and immunogenicity. Vaccine. 2002 Jan 15; 20(7-8):1196-204.
    View in: PubMed
    Score: 0.035
  36. Utility of crossover designs in clinical trials: efficacy of desipramine vs. placebo in opioid-dependent cocaine abusers. Am J Addict. 2002; 11(2):111-23.
    View in: PubMed
    Score: 0.035
  37. A randomized trial of safety and pharmacodynamic interactions between a selective glucocorticoid receptor antagonist, PT150, and ethanol in healthy volunteers. Sci Rep. 2021 05 10; 11(1):9876.
    View in: PubMed
    Score: 0.033
  38. Thrice-weekly versus daily buprenorphine maintenance. Biol Psychiatry. 2000 Jun 15; 47(12):1072-9.
    View in: PubMed
    Score: 0.031
  39. Doxazosin treatment in cocaine use disorder: pharmacogenetic response based on an alpha-1 adrenoreceptor subtype D genetic variant. Am J Drug Alcohol Abuse. 2020; 46(2):184-193.
    View in: PubMed
    Score: 0.030
  40. Lofexidine in Combination With Oral Naltrexone for Opioid Use Disorder Relapse Prevention: A Pilot Randomized, Double-Blind, Placebo-Controlled Study. Am J Addict. 2019 11; 28(6):480-488.
    View in: PubMed
    Score: 0.030
  41. The effect of minocycline on amelioration of cognitive deficits and pro-inflammatory cytokines levels in patients with schizophrenia. Schizophr Res. 2019 10; 212:92-98.
    View in: PubMed
    Score: 0.030
  42. Interactions of cocaine with nimodipine: a brief report. Am J Addict. 1999; 8(1):77-81.
    View in: PubMed
    Score: 0.028
  43. The effect of lamotrigine on naloxone-precipitated opiate withdrawal. Drug Alcohol Depend. 1998 Oct 01; 52(2):173-6.
    View in: PubMed
    Score: 0.028
  44. Minocycline adjunctive treatment to risperidone for negative symptoms in schizophrenia: Association with pro-inflammatory cytokine levels. Prog Neuropsychopharmacol Biol Psychiatry. 2018 07 13; 85:69-76.
    View in: PubMed
    Score: 0.027
  45. Outpatient transition to extended-release injectable naltrexone for patients with opioid use disorder: A phase 3 randomized trial. Drug Alcohol Depend. 2018 06 01; 187:171-178.
    View in: PubMed
    Score: 0.027
  46. Prognostic factors in Buprenorphine- versus methadone-maintained patients. J Nerv Ment Dis. 1998 Jan; 186(1):35-43.
    View in: PubMed
    Score: 0.026
  47. Exenatide once weekly for smoking cessation: study protocol for a randomized clinical trial. Medicine (Baltimore). 2018 Jan; 97(2):e9567.
    View in: PubMed
    Score: 0.026
  48. Moderators of response to sertraline versus placebo among recently abstinent, cocaine dependent patients: A retrospective analysis of two clinical trials. Am J Addict. 2017 Dec; 26(8):807-814.
    View in: PubMed
    Score: 0.026
  49. Treatment of early AIDS dementia in intravenous drug users: high versus low dose peptide T. Am J Drug Alcohol Abuse. 1997 Nov; 23(4):543-53.
    View in: PubMed
    Score: 0.026
  50. Buprenorphine vs methadone maintenance treatment for concurrent opioid dependence and cocaine abuse. Arch Gen Psychiatry. 1997 Aug; 54(8):713-20.
    View in: PubMed
    Score: 0.026
  51. Guanfacine Attenuates Adverse Effects of Dronabinol (THC) on Working Memory in Adolescent-Onset Heavy Cannabis Users: A Pilot Study. J Neuropsychiatry Clin Neurosci. 2018; 30(1):66-76.
    View in: PubMed
    Score: 0.025
  52. Dose dependent effects of yohimbine on methadone maintained patients. Am J Drug Alcohol Abuse. 1997 May; 23(2):327-33.
    View in: PubMed
    Score: 0.025
  53. Effects of gamma-hydroxybutyric acid (GHB) in opioid-dependent patients. J Subst Abuse Treat. 1997 Mar-Apr; 14(2):149-54.
    View in: PubMed
    Score: 0.025
  54. Sustained-release methylphenidate for cognitive impairment in HIV-1-infected drug abusers: a pilot study. J Neuropsychiatry Clin Neurosci. 1997; 9(1):29-36.
    View in: PubMed
    Score: 0.025
  55. The a-1 adrenoceptor (ADRA1A) genotype moderates the magnitude of acute cocaine-induced subjective effects in cocaine-dependent individuals. Pharmacogenet Genomics. 2016 09; 26(9):428-35.
    View in: PubMed
    Score: 0.024
  56. Subjective and Cardiovascular Effects of Intravenous Methamphetamine during Perindopril Maintenance: A Randomized, Double-Blind, Placebo-Controlled Human Laboratory Study. Int J Neuropsychopharmacol. 2016 07; 19(7).
    View in: PubMed
    Score: 0.024
  57. A pilot study of dextromethorphan in naloxone-precipitated opiate withdrawal. Eur J Pharmacol. 1996 Jul 04; 307(3):251-7.
    View in: PubMed
    Score: 0.024
  58. Mazindol for relapse prevention to cocaine abuse in methadone-maintained patients. Am J Drug Alcohol Abuse. 1995 Nov; 21(4):469-81.
    View in: PubMed
    Score: 0.023
  59. Behavioral, physiological, and pharmacological interaction of cocaine and disulfiram in humans. Biol Psychiatry. 1995 Apr 15; 37(8):560-3.
    View in: PubMed
    Score: 0.022
  60. Effects of ethnicity on low-dose opiate stabilization. J Subst Abuse Treat. 1995 Mar-Apr; 12(2):111-6.
    View in: PubMed
    Score: 0.022
  61. A Double-Blind, Placebo-Controlled Trial to Evaluate the Safety, Tolerability, and Pharmacokinetics of Single, Escalating Oral Doses of JDTic. Neuropsychopharmacology. 2015 Aug; 40(9):2059-65.
    View in: PubMed
    Score: 0.022
  62. Reduction of opiate withdrawal-like symptoms by cocaine abuse during methadone and buprenorphine maintenance. Am J Drug Alcohol Abuse. 1994 Nov; 20(4):445-58.
    View in: PubMed
    Score: 0.021
  63. The influence of dopamine ?-hydroxylase gene polymorphism rs1611115 on levodopa/carbidopa treatment for cocaine dependence: a preliminary study. Pharmacogenet Genomics. 2014 Jul; 24(7):370-3.
    View in: PubMed
    Score: 0.021
  64. Clinical efficacy of sertraline alone and augmented with gabapentin in recently abstinent cocaine-dependent patients with depressive symptoms. J Clin Psychopharmacol. 2014 Apr; 34(2):234-9.
    View in: PubMed
    Score: 0.020
  65. Buprenorphine versus methadone maintenance for opioid dependence. J Nerv Ment Dis. 1993 Jun; 181(6):358-64.
    View in: PubMed
    Score: 0.019
  66. Gender differences in cocaine use and treatment response. J Subst Abuse Treat. 1993 Jan-Feb; 10(1):63-6.
    View in: PubMed
    Score: 0.019
  67. The impact of disulfiram treatment on the reinforcing effects of cocaine: a randomized clinical trial. PLoS One. 2012; 7(11):e47702.
    View in: PubMed
    Score: 0.018
  68. Pharmacotherapy for cocaine-abusing methadone-maintained patients using amantadine or desipramine. Arch Gen Psychiatry. 1992 Nov; 49(11):894-8.
    View in: PubMed
    Score: 0.018
  69. Association of functional COMT Val108/Met polymorphism with smoking cessation in a nicotine replacement therapy. J Neural Transm (Vienna). 2012 Dec; 119(12):1491-8.
    View in: PubMed
    Score: 0.018
  70. Phase II clinical trials of buprenorphine: detoxification and induction onto naltrexone. NIDA Res Monogr. 1992; 121:101-19.
    View in: PubMed
    Score: 0.017
  71. Pharmacotherapy improves treatment outcome in depressed cocaine addicts. J Psychoactive Drugs. 1991 Oct-Dec; 23(4):417-25.
    View in: PubMed
    Score: 0.017
  72. Pharmacotherapy for posttraumatic stress disorder using phenelzine or imipramine. J Nerv Ment Dis. 1991 Jun; 179(6):366-70.
    View in: PubMed
    Score: 0.017
  73. Behavioral effects of gamma-hydroxybutyrate in humans. Behav Pharmacol. 2010 Jul; 21(4):332-42.
    View in: PubMed
    Score: 0.016
  74. Mazindol treatment of cocaine abuse. A double-blind investigation. NIDA Res Monogr. 1990; 105:514.
    View in: PubMed
    Score: 0.015
  75. Rapid detoxification from opioid dependence. Am J Psychiatry. 1989 Oct; 146(10):1349.
    View in: PubMed
    Score: 0.015
  76. Effect of rapamycin on cue-induced drug craving in abstinent heroin addicts. Eur J Pharmacol. 2009 Aug 01; 615(1-3):108-12.
    View in: PubMed
    Score: 0.015
  77. Family support and employment as predictors of smoking cessation success: a randomized, double-blind, placebo-controlled trial of nicotine sublingual tablets in chinese smokers. Am J Drug Alcohol Abuse. 2009; 35(3):183-8.
    View in: PubMed
    Score: 0.014
  78. Preliminary study of buprenorphine and bupropion for opioid-dependent smokers. Am J Addict. 2008 Jul-Aug; 17(4):287-92.
    View in: PubMed
    Score: 0.014
  79. Clinical efficacy of citalopram alone or augmented with bupropion in methadone-stabilized patients. Am J Addict. 2007 May-Jun; 16(3):187-94.
    View in: PubMed
    Score: 0.013
  80. Clinical efficacy of gabapentin versus tiagabine for reducing cocaine use among cocaine dependent methadone-treated patients. Drug Alcohol Depend. 2007 Feb 23; 87(1):1-9.
    View in: PubMed
    Score: 0.012
  81. Comparison of clinician ratings to self reports of withdrawal during clonidine detoxification of opiate addicts. Am J Drug Alcohol Abuse. 1985; 11(1-2):1-10.
    View in: PubMed
    Score: 0.011
  82. Effects of naltrexone and isradipine, alone or in combination, on cocaine responses in humans. Pharmacol Biochem Behav. 2003 Jul; 75(4):801-8.
    View in: PubMed
    Score: 0.010
  83. Yohimbine-induced withdrawal and anxiety symptoms in opioid-dependent patients. Biol Psychiatry. 2002 Apr 15; 51(8):642-51.
    View in: PubMed
    Score: 0.009
  84. Methadone patients exhibit increased startle and cortisol response after intravenous yohimbine. Psychopharmacology (Berl). 2001 Mar; 154(3):274-81.
    View in: PubMed
    Score: 0.008
  85. Sex differences in self-reported and physiological response to oral cocaine and placebo in humans. Am J Drug Alcohol Abuse. 2000 Nov; 26(4):643-57.
    View in: PubMed
    Score: 0.008
  86. The effects of naltrexone maintenance on the response to yohimbine in healthy volunteers. Biol Psychiatry. 1999 Jun 15; 45(12):1636-45.
    View in: PubMed
    Score: 0.007
  87. Disulfiram effects on acute cocaine administration. Drug Alcohol Depend. 1998 Sep 01; 52(1):27-39.
    View in: PubMed
    Score: 0.007
  88. Concurrent use of cocaine and alcohol is more potent and potentially more toxic than use of either alone--a multiple-dose study. Biol Psychiatry. 1998 Aug 15; 44(4):250-9.
    View in: PubMed
    Score: 0.007
  89. Chronic disulfiram treatment effects on intranasal cocaine administration: initial results. Biol Psychiatry. 1998 Apr 01; 43(7):540-3.
    View in: PubMed
    Score: 0.007
  90. Three methods of opioid detoxification in a primary care setting. A randomized trial. Ann Intern Med. 1997 Oct 01; 127(7):526-30.
    View in: PubMed
    Score: 0.006
  91. Effect of alpha-methyl-para-tyrosine on response to cocaine challenge. Biol Psychiatry. 1997 Aug 01; 42(3):181-90.
    View in: PubMed
    Score: 0.006
  92. Decreased digital flow persists after the abatement of cocaine-induced hemodynamic stimulation. Anesth Analg. 1997 Jan; 84(1):46-50.
    View in: PubMed
    Score: 0.006
  93. A multicenter trial of bupropion for cocaine dependence in methadone-maintained patients. Drug Alcohol Depend. 1995 Dec; 40(2):125-31.
    View in: PubMed
    Score: 0.006
  94. Desipramine, amantadine, or fluoxetine in buprenorphine-maintained cocaine users. J Subst Abuse Treat. 1995 Nov-Dec; 12(6):423-8.
    View in: PubMed
    Score: 0.006
  95. Mazindol treatment for cocaine dependence. Drug Alcohol Depend. 1995 Oct; 39(3):245-52.
    View in: PubMed
    Score: 0.006
  96. Cocaethylene: pharmacology, physiology and behavioral effects in humans. J Pharmacol Exp Ther. 1995 Jul; 274(1):215-23.
    View in: PubMed
    Score: 0.006
  97. Tryptophan depletion and attenuation of cue-induced craving for cocaine. Am J Psychiatry. 1995 May; 152(5):778-83.
    View in: PubMed
    Score: 0.005
  98. Opiate dependence and withdrawal: preliminary assessment using single photon emission computerized tomography (SPECT). Am J Drug Alcohol Abuse. 1995 Feb; 21(1):47-63.
    View in: PubMed
    Score: 0.005
  99. Noradrenergic dysregulation during discontinuation of cocaine use in addicts. Arch Gen Psychiatry. 1994 Sep; 51(9):713-9.
    View in: PubMed
    Score: 0.005
  100. Concurrent cocaine-ethanol ingestion in humans: pharmacology, physiology, behavior, and the role of cocaethylene. Psychopharmacology (Berl). 1993; 111(1):39-46.
    View in: PubMed
    Score: 0.005
  101. Desipramine facilitation of initial cocaine abstinence. Arch Gen Psychiatry. 1989 Feb; 46(2):117-21.
    View in: PubMed
    Score: 0.004
  102. Double-blind evaluation of the effect of acute amantadine on cocaine craving. Psychopharmacology (Berl). 1989; 97(3):402-3.
    View in: PubMed
    Score: 0.004
  103. Nontolerance to the opioid antagonism of naltrexone. Biol Psychiatry. 1985 Jan; 20(1):66-72.
    View in: PubMed
    Score: 0.003
Connection Strength

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Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.