"Pentoxifylline" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A METHYLXANTHINE derivative that inhibits phosphodiesterase and affects blood rheology. It improves blood flow by increasing erythrocyte and leukocyte flexibility. It also inhibits platelet aggregation. Pentoxifylline modulates immunologic activity by stimulating cytokine production.
| Descriptor ID |
D010431
|
| MeSH Number(s) |
D03.633.100.759.758.824.651.700
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Pentoxifylline".
Below are MeSH descriptors whose meaning is more specific than "Pentoxifylline".
This graph shows the total number of publications written about "Pentoxifylline" by people in this website by year, and whether "Pentoxifylline" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 1 | 0 | 1 |
| 2001 | 0 | 1 | 1 |
| 2003 | 2 | 0 | 2 |
| 2004 | 0 | 1 | 1 |
| 2005 | 1 | 0 | 1 |
| 2007 | 1 | 0 | 1 |
| 2011 | 1 | 0 | 1 |
| 2012 | 0 | 1 | 1 |
| 2015 | 1 | 0 | 1 |
| 2017 | 0 | 2 | 2 |
| 2020 | 1 | 0 | 1 |
| 2023 | 1 | 0 | 1 |
| 2024 | 1 | 0 | 1 |
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Below are the most recent publications written about "Pentoxifylline" by people in Profiles.
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Pentoxifylline protects memory performance in streptozotocin-induced diabetic rats. Brain Res. 2025 Jan 15; 1847:149319.
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Pentoxifylline for treatment of sepsis and necrotising enterocolitis in neonates. Cochrane Database Syst Rev. 2023 06 20; 6:CD004205.
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Granuloma Annulare: An Updated Review of Epidemiology, Pathogenesis, and Treatment Options. Am J Clin Dermatol. 2022 Jan; 23(1):37-50.
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Pentoxifylline and Tocopherol in the Management of Temporal Bone Osteoradionecrosis: A Case Series. Otol Neurotol. 2020 12; 41(10):1438-1446.
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Severe pretibial myxedema refractory to systemic immunosuppressants. Cutis. 2019 Sep; 104(3):E1-E3.
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Novel Indications for Commonly Used Medications as Radiation Protectants in Spaceflight. Aerosp Med Hum Perform. 2017 Jul 01; 88(7):665-676.
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Neonatal sepsis. Lancet. 2017 Oct 14; 390(10104):1770-1780.
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Pentoxifylline Ameliorates Mechanical Hyperalgesia in a Rat Model of Chemotherapy-Induced Neuropathic Pain. Pain Physician. 2016 05; 19(4):E589-600.
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Pentoxifylline for treatment of sepsis and necrotizing enterocolitis in neonates. Cochrane Database Syst Rev. 2015 Mar 09; (3):CD004205.
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Novel treatments for NEC: keeping IBD in mind. Curr Gastroenterol Rep. 2012 Oct; 14(5):373-9.