"Landau-Kleffner Syndrome" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A syndrome characterized by the onset of isolated language dysfunction in otherwise normal children (age of onset 4-7 years) and epileptiform discharges on ELECTROENCEPHALOGRAPHY. Seizures, including atypical absence (EPILEPSY, ABSENCE), complex partial (EPILEPSY, COMPLEX PARTIAL), and other types may occur. The electroencephalographic abnormalities and seizures tend to resolve by puberty. The language disorder may also resolve although some individuals are left with severe language dysfunction, including APHASIA and auditory AGNOSIA. (From Menkes, Textbook of Child Neurology, 5th ed, pp749-50; J Child Neurol 1997 Nov;12(8):489-495).
| Descriptor ID |
D018887
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| MeSH Number(s) |
C10.228.140.490.493.500
|
| Concept/Terms |
Landau-Kleffner Syndrome- Landau-Kleffner Syndrome
- Landau Kleffner Syndrome
- Syndrome, Landau-Kleffner
- Aphasia, Epileptic, Acquired
- Aphasia, Acquired, With Convulsive Disorder
- Landau-Kleffner Acquired Epileptiform Aphasia
- Landau Kleffner Acquired Epileptiform Aphasia
- Acquired Aphasia with Convulsive Disorder
- Acquired Epileptiform Aphasia
- Acquired Epileptiform Aphasias
- Epileptiform Aphasia, Acquired
- Epileptiform Aphasias, Acquired
- Aphasia, Acquired Epileptic
- Acquired Epileptic Aphasia
- Acquired Epileptic Aphasias
- Epileptic Aphasia, Acquired
- Epileptic Aphasias, Acquired
- Acquired Childhoood Aphasia with Convulsive Disorder
|
Below are MeSH descriptors whose meaning is more general than "Landau-Kleffner Syndrome".
Below are MeSH descriptors whose meaning is more specific than "Landau-Kleffner Syndrome".
This graph shows the total number of publications written about "Landau-Kleffner Syndrome" by people in this website by year, and whether "Landau-Kleffner Syndrome" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 1 | 0 | 1 |
| 2004 | 1 | 0 | 1 |
| 2005 | 1 | 0 | 1 |
| 2014 | 1 | 0 | 1 |
| 2017 | 1 | 0 | 1 |
| 2022 | 2 | 0 | 2 |
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Below are the most recent publications written about "Landau-Kleffner Syndrome" by people in Profiles.
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Koolen-de Vries syndrome associated with continuous spike-wave in sleep Epileptic Disord. 2022 10 01; 24(5):928-933.
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Mild neurological phenotype in a family carrying a novel N-terminal null GRIN2A variant. Eur J Med Genet. 2022 May; 65(5):104500.
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A de novo loss-of-function GRIN2A mutation associated with childhood focal epilepsy and acquired epileptic aphasia. PLoS One. 2017; 12(2):e0170818.
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Increasing blurriness of the borders between focal and generalized as well as cryptogenic and idiopathic epilepsies in defining the role for focal epilepsy surgery. Semin Pediatr Neurol. 2014 Jun; 21(2):104-5.
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Episodic epileptic verbal auditory agnosia in Landau Kleffner syndrome treated with combination diazepam and corticosteroids. J Child Neurol. 2014 Oct; 29(10):1291-8.
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Brain-derived neurotrophic factor and autoantibodies to neural antigens in sera of children with autistic spectrum disorders, Landau-Kleffner syndrome, and epilepsy. Biol Psychiatry. 2006 Feb 15; 59(4):354-63.
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Bilateral volume reduction of the superior temporal areas in Landau-Kleffner syndrome. Neurology. 2004 Oct 12; 63(7):1289-92.
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Visual hallucinations associated with zonisamide. Pharmacotherapy. 2003 Jan; 23(1):93-6.